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The irrigation effect on nuts' growth and yield of Carya illinoinensis.

An Acad Bras Cienc 2021 31;93(1):e20181351. Epub 2021 Mar 31.

Departamento de Agronomia, Universidade Federal da Fronteira do Sul, Rodovia SC 484, Km 02, Fronteira Sul, 89815-899 Chapecó, SC, Brazil.

Pecan trees require adequate soil moisture conditions to produce nuts with good yield and quality. Irrigation should be an important considered practice in orchards management plan, mainly in regions with water deficit periods. The objective of this research was to evaluate irrigation on pecan nuts growth and yield. Read More

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Sexually transmitted infections and human immunodeficiency virus coinfection: Scenario in Western India.

Indian J Sex Transm Dis AIDS 2020 Jul-Dec;41(2):162-168. Epub 2020 Jul 31.

Department of Dermatology, B. J. Medical College, Ahmedabad, Gujarat, India.

Context: Sexually transmitted infections (STIs) have a well-established synergistic relationship with human immunodeficiency virus (HIV) infection. Coinfection with HIV and STI can increase the probability of HIV transmission to an uninfected partner by increasing HIV concentrations in genital lesions, genital secretions, or both. Concurrent HIV infection alters the natural history of the classic STIs. Read More

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Can conditions of skeletal muscle loss be improved by combining exercise with anabolic-androgenic steroids? A systematic review and meta-analysis of testosterone-based interventions.

Rev Endocr Metab Disord 2021 Mar 30. Epub 2021 Mar 30.

Medical School, Federal University of Fronteira Sul, SC 484 - Km 02, Chapecó, Santa Catarina, Brazil.

Sarcopenia, cachexia, and atrophy due to inactivity and disease states are characterized by a loss of skeletal muscle mass, often accompanied by reduced levels of anabolic hormones (e.g. testosterone). Read More

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Risk Factors for Central and Lateral Lymph Node Metastases in Patients With Papillary Thyroid Micro-Carcinoma: Retrospective Analysis on 484 Cases.

Front Endocrinol (Lausanne) 2021 5;12:640565. Epub 2021 Mar 5.

Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Background: Papillary thyroid micro-carcinoma (PTMC) is defined as a tumor with a larger diameter ≤1 cm which has an indolent course and satisfying prognosis. However, the incidence of lymph node metastasis of PTMC cannot be ignored. The aim of this study was to assess the incidence of lymph node metastasis in PTMC patients, as well as to evaluate the risk factors for both central lymph node metastases (CLNM) and lateral lymph node metastases (LLNM). Read More

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First report of causing stem canker on L. in Oregon.

Authors:
Andrea Garfinkel

Plant Dis 2021 Mar 17. Epub 2021 Mar 17.

Oregon CBD, 3395 S Pacific Hwy W, Independence, Oregon, United States, 97351;

In August of 2020, plants of L. grown in hoop houses at two farms located in Benton County, Oregon exhibited wilting and chlorosis, followed by shoot necrosis. Symptomatic plants had dry, tan-brown lesions or cankers, often accompanied by large, round to irregular or ribbon-shaped, black sclerotia and/or profuse white mycelial growth. Read More

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By targeting apoptosis facilitator BCL2L13, microRNA miR-484 alleviates cerebral ischemia/reperfusion injury-induced neuronal apoptosis in mice.

Bioengineered 2021 Dec;12(1):948-959

Department of Cerebrovascular Disease, The Second Affiliated Hospital of Guilin Medical University, Guilin City, Guangxi Zhuang Autonomous Region, China.

Neuronal apoptosis was considered as one of the main factors of cerebral ischemia/reperfusion injury. Understanding the molecular regulatory mechanism of neuronal apoptosis under the cerebral ischemia/reperfusion injury may provide the novel therapeutic targets for cerebral ischemia/reperfusion injury. However, the molecular regulatory mechanism of neurons fate determination under the cerebral ischemia/reperfusion injury remains poorly understood. Read More

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December 2021

UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records.

BMC Public Health 2021 03 11;21(1):484. Epub 2021 Mar 11.

NIHR Health Protection Research Unit (HPRU) in Immunisation, London, UK.

Background: Characterising the size and distribution of the population at risk of severe COVID-19 is vital for effective policy and planning. Older age, and underlying health conditions, are associated with higher risk of death from COVID-19. This study aimed to describe the population at risk of severe COVID-19 due to underlying health conditions across the United Kingdom. Read More

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Endurance training alters motor unit activation strategies for the vastus lateralis, yet sex-related differences and relationships with muscle size remain.

Eur J Appl Physiol 2021 Feb 18. Epub 2021 Feb 18.

Department of Human Physiology, Gonzaga University, Spokane, WA, USA.

Purpose: To examine the effects of 10 weeks of endurance cycling training on mechanomyographic amplitude (MMG)-torque relationships and muscle cross-sectional area (mCSA) of the vastus lateralis (VL) for 10 sedentary males (Age ± SD; 20.2 ± 1.9 years) and 14 sedentary females (21. Read More

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February 2021

Impact of ultrasound processing parameters on physical characteristics of lycopene emulsion.

J Food Sci Technol 2021 Feb 19;58(2):484-493. Epub 2020 Jun 19.

Department of Food Science and Technology, Research Institute of Food Science and Technology, Mashhad, Iran.

Using ultrasound technology for obtaining O/W lycopene emulsions needs analyzing the parameters for the enhanced application. To this end, O/W lycopene emulsions (30:70) were processed using ultrasound with powers of 240 W and 360 W in 5, 10, and 15 min. Afterward, the poly dispersity index, droplet size, ζ-potential, turbidity, phase separation, lycopene concentration, rheological behavior, surface tension, and morphology of emulsions was investigated. Read More

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February 2021

Full-Length Genome and Partial Viral Genes Phylogenetic and Geographical Analysis of Dengue Serotype 3 Isolates.

Microorganisms 2021 Feb 4;9(2). Epub 2021 Feb 4.

Faculty of Medicine, University of Medicine and Pharmacy Carol Davila, 020021 Bucharest, Romania.

Dengue fever is among the most common vector-borne diseases. Dengue virus (DENV), responsible for dengue fever as well as dengue hemorrhagic fever, belongs to the genus flavivirus and family Flaviviridae. Flaviviruses infect various vertebrate species and arthropods and are also responsible for diseases in birds, wild animals, and primates. Read More

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February 2021

Risk factors associated with missed colorectal lesions in colonoscopy and impact of colonoscopy with anesthesia on miss rate.

Scand J Gastroenterol 2021 Apr 8;56(4):484-491. Epub 2021 Feb 8.

Department of Gastroenterology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, PR China.

Objectives: To systematically determine the miss rate and risk factors for polyps, adenomas and advanced adenomas in the same population, and to further analyze the impact of colonoscopy with anesthesia on miss rate.

Methods: We retrospectively analyzed the information of the patients undergoing the second colonoscopy within 1 year after their first. The patient and lesion miss rate were calculated. Read More

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Linking Quality and Quantity of Parental Linguistic Input to Child Language Skills: A Meta-Analysis.

Child Dev 2021 Mar 31;92(2):484-501. Epub 2021 Jan 31.

University of Calgary.

This meta-analysis examined associations between the quantity and quality of parental linguistic input and children's language. Pooled effect size for quality (i.e. Read More

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Iodopovidone pleurodesis for malignant pleural effusions: an updated systematic review and meta-analysis.

Support Care Cancer 2021 Jan 30. Epub 2021 Jan 30.

Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Sector-12, Chandigarh, 160012, India.

Background: Chemical pleurodesis is an important option for palliation in malignant pleural effusion (MPE).

Objectives: To evaluate the status of iodopovidone for pleurodesis in MPE.

Methods: We performed a systematic review of PubMed and EMBASE databases to identify studies evaluating the role of iodopovidone for pleurodesis in MPE. Read More

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January 2021

Association between plantar flexor muscle volume and dorsiflexion flexibility in healthy young males: ultrasonography and magnetic resonance imaging studies.

BMC Sports Sci Med Rehabil 2021 Jan 29;13(1). Epub 2021 Jan 29.

Faculty of Sport and Health Science, Ritsumeikan University, 1-1-1 Nojihigashi, 525-8577, Kusatsu, Shiga, Japan.

Background: Although joint flexibility is important for human locomotion, the determinants of joint flexibility are not fully understood. In this study, we examined the relationship between dorsiflexion flexibility and plantar flexor muscle size in healthy young males.

Methods And Results: The dorsiflexion flexibility was assessed using range of motion (ROM) and stiffness during active and passive dorsiflexion. Read More

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January 2021

Correlation of Fecal Immunochemical Testing Levels With Pathology Results in a National Colorectal Cancer Screening Program.

Clin Transl Gastroenterol 2021 Jan 12;12(1):e00277. Epub 2021 Jan 12.

Center for Colorectal Disease, St Vincent's University Hospital, Dublin 4, Ireland.

Introduction: Fecal immunochemical testing (FIT) positivity is determined by a threshold decided by individual screening programs. Data are limited on correlation between FIT levels and pathology identified at colonoscopy. Our aim was to examine the correlation between FIT levels and pathology identified in a national colorectal cancer screening program. Read More

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January 2021

Synthesis of ZnO/Au Nanorods for Self Cleaning Applications.

J Nanosci Nanotechnol 2021 Apr;21(4):2621-2625

Faculty of Physics, VNU-University of Science, Vietnam National University Hanoi, 334 Nguyen Trai, Thanh Xuan, 120000, Hanoi.

Zinc oxide (ZnO) is a well-known semiconductor with valuable characteristics: wide direct band gap of ˜3.3 eV, large exciton binding energy of 60 meV at room temperature, high efficient photocatalyst, etc. which have been applied in many fields such as optical devices (LEDs, laser), solar cells and sensors. Read More

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Magnesium Oxychloride Cement Composites with MWCNT for the Construction Applications.

Materials (Basel) 2021 Jan 20;14(3). Epub 2021 Jan 20.

Department of Inorganic Chemistry, Faculty of Chemical Technology, University of Chemistry and Technology, Technická 5, 166 28 Prague 6, Czech Republic.

In this contribution, composite materials based on magnesium oxychloride cement (MOC) with multi-walled carbon nanotubes (MWCNTs) used as an additive were prepared and characterized. The prepared composites contained 0.5 and 1 wt. Read More

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January 2021

Improved Safety and Anti-Glioblastoma Efficacy of CAT3-Encapsulated SMEDDS through Metabolism Modification.

Molecules 2021 Jan 18;26(2). Epub 2021 Jan 18.

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

13-()-3-pivaloyloxyl-6,7-dimethoxyphenanthro(9,10-)-indolizidine (CAT3) is a novel oral anti-glioma pro-drug with a potent anti-tumor effect against temozolomide-resistant glioma. 13()-3-hydroxyl-6,7-dimethoxyphenanthro(9,10-)-indolizidine (PF403) is the active in vivo lipase degradation metabolite of CAT3. Both CAT3 and PF403 can penetrate the blood-brain barrier to cause an anti-glioma effect. Read More

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January 2021

Comparison between laparoscopic and abdominal radical hysterectomy for stage IB1 and tumor size <2 cm cervical cancer with visible or invisible tumors: a multicentre retrospective study.

J Gynecol Oncol 2021 Mar 14;32(2):e17. Epub 2020 Dec 14.

Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Objective: To compare 5-year disease-free survival (DFS) and overall survival (OS) rates of laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) for stage IB1 and tumor size <2 cm with visible or invisible tumors.

Methods: We retrospectively compared the oncological outcomes of 1,484 cervical cancer patients with IB1 and tumor size <2 cm on final pathology, who received ARH (n=899) or LRH (n=585) between January 2004 and December 2016. Patients were divided into visible tumor subgroup (ARH: n=668, LRH: n=444) and invisible tumor subgroup (ARH: n=231, LRH: n=141) according to tumor type. Read More

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The complete chloroplast genome sequence of (Juglandaceae), an Endangered species endemic to Yunnan Province, China.

Mitochondrial DNA B Resour 2020 May 12;5(3):2021-2023. Epub 2020 May 12.

APFNet Kunming Training Center, Southwest Forestry University, Kunming, China.

, a plant species with extremely small populations endemic to Xichou county of Yunnan province, has been classified as a national second-class protected wild plant. In this study, we assembled its complete chloroplast genome. The total genome size of was 158,484 bp in length, containing a large single-copy region of 89,871 bp, a small single-copy region of 20,558 bp, and a pair of inverted repeat regions of 24,029 bp. Read More

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Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition.

Genome Res 2021 Mar 13;31(3):484-496. Epub 2021 Jan 13.

Human Genetics and Cognitive Functions, Institut Pasteur, UMR3571 CNRS, Université de Paris, Paris 75015, France.

The human brain differs from that of other primates, but the genetic basis of these differences remains unclear. We investigated the evolutionary pressures acting on almost all human protein-coding genes ( = 11,667; 1:1 orthologs in primates) based on their divergence from those of early hominins, such as Neanderthals, and non-human primates. We confirm that genes encoding brain-related proteins are among the most strongly conserved protein-coding genes in the human genome. Read More

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Comparing Safety and Efficacy of Rivaroxaban with Warfarin for Patients after Successful Stent Placement for Chronic Iliofemoral Occlusion: A Retrospective Single Institution Study.

Eur J Vasc Endovasc Surg 2021 03 31;61(3):484-489. Epub 2020 Dec 31.

Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China; Vascular Centre of Shanghai JiaoTong University, Shanghai, China. Electronic address:

Objective: The aim was to compare the safety and effectiveness of rivaroxaban and warfarin as anticoagulants for treating patients with post-thrombotic syndrome (PTS) with chronic iliofemoral venous occlusion undergoing iliofemoral venous stenting.

Methods: This single institution retrospective study analysed patients with PTS with chronic iliofemoral venous occlusion who were prescribed rivaroxaban or warfarin for one year after successfully undergoing iliofemoral venous stenting. The primary safety and efficacy endpoints were bleeding complication rate and primary patency rate at one year. Read More

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Investigating CAG/CAA trinucleotide repeat expansions in a Taiwanese cohort with ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2020 Dec 30:1-6. Epub 2020 Dec 30.

Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.

Intermediate-length CAG repeats in have been well recognized as a genetic risk factor for amyotrophic lateral sclerosis (ALS). However, the role of similar trinucleotide repeat expansions in the TATA-box binding protein gene (), another disease-associated gene for inherited ataxia, in ALS remains elusive. To assess the association between trinucleotide repeat expansions and ALS, we investigated the repeat lengths in 325 unrelated ALS patients and 1500 controls in the Taiwanese population. Read More

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December 2020

Apremilast Microemulsion as Topical Therapy for Local Inflammation: Design, Characterization and Efficacy Evaluation.

Pharmaceuticals (Basel) 2020 Dec 21;13(12). Epub 2020 Dec 21.

Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.

Apremilast (APR) is a selective phosphodiesterase 4 inhibitor administered orally in the treatment of moderate-to-severe plaque psoriasis and active psoriatic arthritis. The low solubility and permeability of this drug hinder its dermal administration. The purpose of this study was to design and characterize an apremilast-loaded microemulsion (APR-ME) as topical therapy for local skin inflammation. Read More

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December 2020

Isolation, purification and characterization of cellulase produced by cultured on shells.

Heliyon 2020 Dec 7;6(12):e05668. Epub 2020 Dec 7.

Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, P.M.B. 1515, Ilorin, Nigeria.

Cellulases are enzymes that hydrolyse cellulose and related cellu-oligosaccharides derivatives. Its applications are enormous but high cost of production is the bottle-neck against the utilization of cellulase in industries. Therefore, this study investigated the isolation, purification and characterization of cellulase produced by cultured on shells. Read More

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December 2020

Potential causal factors of CFS/ME: a concise and systematic scoping review of factors researched.

J Transl Med 2020 12 14;18(1):484. Epub 2020 Dec 14.

Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.

Background: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is understood as a complex condition, likely triggered and sustained by an interplay of biological, psychological, and social factors. Little oversight exists of the field of causal research. This systematic scoping review explores potential causal factors of CFS/ME as researched by primary studies. Read More

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December 2020

Long-Term Prognosis of Moderate to Severe Coronary Artery Calcification in Patients Undergoing Percutaneous Coronary Intervention.

Circ J 2020 Dec 9;85(1):50-58. Epub 2020 Dec 9.

Department of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College & Chinese Academy of Medical Sciences.

Background: Moderate/severe coronary artery calcification (CAC) predicts worse clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). However, to date most studies have been modest in size and with limited follow-up. We aimed to assess the association between calcification severity and long-term clinical outcomes in a large cohort undergoing PCI. Read More

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December 2020

Improving quality in general practice using the Primary Care Practice Improvement Tool (PC-PIT) with Primary Health Network support.

Aust J Prim Health 2020 Dec;26(6):484-491

Centre for Health System Reform and Integration, University of Queensland-Mater Research Institute, Level 8, Health Sciences Building, Royal Brisbane & Women's Hospital Campus, Herston, Qld 4006, Australia.

Optimal primary care sector performance is vital for ensuring the delivery of quality health services and effective clinical management of populations. The Primary Care Practice Improvement Tool (PC-PIT) incorporates subjective staff input and objective indicators to measure 13 elements of organisational performance. This study aimed to measure change in organisational performance for general practices using the PC-PIT with Primary Health Network (PHN) support. Read More

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December 2020

Arsenic geochemistry and mineralogy as a function of particle-size in naturally arsenic-enriched soils.

J Hazard Mater 2021 02 16;403:123931. Epub 2020 Sep 16.

Global Centre for Environmental Remediation (GCER), Faculty of Science, The University of Newcastle, Callaghan, New South Wales 2308, Australia; Cooperative Research Centre for Contamination Assessment and Remediation of the Environment (CRC-CARE), ATC Building, The University of Newcastle, Callaghan, New South Wales 2308, Australia. Electronic address:

Naturally arsenic (As) enriched agricultural soils represent a significant global human health risk. In this study, As fractionation and mineralogy were investigated in naturally As-enriched agricultural soils and their corresponding sand, silt and clay fractions. Median As increased generally in the order (mg/kg)∶ silt (280) < bulk (314) < sand (323)Read More

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February 2021