BMC Med Imaging 2021 Sep 16;21(1):133. Epub 2021 Sep 16.
Department of Nuclear Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Rd, Jianggan District, Hangzhou, 310000, Zhejiang, People's Republic of China.
Background: To compare the changes in quantitative parameters and the size and degree of F-fluorodeoxyglucose ([F]FDG) uptake of malignant tumor lesions between Bayesian penalized-likelihood (BPL) and non-BPL reconstruction algorithms.
Methods: Positron emission tomography/computed tomography images of 86 malignant tumor lesions were reconstructed using the algorithms of ordered subset expectation maximization (OSEM), OSEM + time of flight (TOF), OSEM + TOF + point spread function (PSF), and BPL. [F]FDG parameters of maximum standardized uptake value (SUVmax), SUVmean, metabolic tumor volume (MTV), total lesion glycolysis (TLG), and signal-to-background ratio (SBR) of these lesions were measured. Read More