2,895 results match your criteria sinusitis time

Infantile orbital abscess: clinical presentation, microbiological profile, and management outcomes.

Orbit 2021 May 11:1-7. Epub 2021 May 11.

Department of Orbit, Oculoplasty, Reconstructive and Aesthetics, Chennai, India.

: Orbital abscesses in children are not uncommon. Unless managed in a timely fashion, they can potentially lead to vision-threatening as well as life-threatening complications. The objective of this study is to report the clinical and microbiological profile and management outcomes in infants presenting with orbital abscesses. Read More

View Article and Full-Text PDF

Microbiology of Acute Maxillary Sinusitis in Children.

Laryngoscope 2021 May 3. Epub 2021 May 3.

Department of Otolaryngology, Matsubara ENT Clinic, Gifu, Japan.

Objectives/hypothesis: Acute rhinosinusitis is a frequent common cold-related complication in children. Despite the need for appropriate treatment, its underlying microbiology remains unclear. This study aimed to investigate the microbiology of acute rhinosinusitis in children. Read More

View Article and Full-Text PDF

Complement Inactivation Strategy of Using Decay-Accelerating Factor and the Response of Infected HaCaT Cells.

Int J Mol Sci 2021 Apr 13;22(8). Epub 2021 Apr 13.

Graduate School of Biotechnology, Kyung Hee University, Yongin 17104, Korea.

is a species of Gram-positive staphylococcus. It can cause sinusitis, respiratory infections, skin infections, and food poisoning. Recently, it was discovered that infects epithelial cells, but the interaction between and the host is not well known. Read More

View Article and Full-Text PDF

Deep Active Learning for Automatic Segmentation of Maxillary Sinus Lesions Using a Convolutional Neural Network.

Diagnostics (Basel) 2021 Apr 12;11(4). Epub 2021 Apr 12.

Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital, Seoul 02841, Korea.

The aim of this study was to segment the maxillary sinus into the maxillary bone, air, and lesion, and to evaluate its accuracy by comparing and analyzing the results performed by the experts. We randomly selected 83 cases of deep active learning. Our active learning framework consists of three steps. Read More

View Article and Full-Text PDF

A scoping review of longitudinal airway microbiota studies.

Expert Rev Respir Med 2021 Apr 28. Epub 2021 Apr 28.

Department of Surgery, The University of Auckland, Auckland, New Zealand.

Introduction: The role of the microbiota in inflammatory airway diseases is unclear. Antimicrobial therapies have predominantly been guided by culture results. However, molecular sequencing has shown that the airway microbiota is much more complex and accurate modeling requires longitudinal analysis. Read More

View Article and Full-Text PDF

Annual trends in Google searches provides insights related to rhinosinusitis exacerbations.

Eur Arch Otorhinolaryngol 2021 Apr 20. Epub 2021 Apr 20.

Department of Otorhinolaryngology, Head and Neck Surgery, Vienna General Hospital (AKH), Medical University of Vienna, Vienna, Austria.

Purpose: Temporal trends of disease-specific internet searches may provide novel insights into seasonal dynamics of disease burden and, by extension, disease pathophysiology. The aim of this study was to define the temporal trends in rhinosinusitis-specific internet searches.

Methods: This was a cross sectional analysis of search volume for predefined search terms. Read More

View Article and Full-Text PDF

Association of US Food and Drug Administration Removal of Indications for Use of Oral Quinolones With Prescribing Trends.

JAMA Intern Med 2021 Apr 19. Epub 2021 Apr 19.

Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville.

Importance: In May 2016, due to concerns of the risks outweighing the benefits, the US Food and Drug Administration (FDA) removed systemic quinolones' indications for acute, uncomplicated urinary tract infection (uUTI), acute sinusitis (AS), and acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). How the change influenced oral quinolone use is unknown.

Objective: To assess the association of oral quinolone safety warnings and indication restrictions with use. Read More

View Article and Full-Text PDF

Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials.

Expert Rev Clin Pharmacol 2021 Apr 26:1-18. Epub 2021 Apr 26.

CIBER De Enfermedades Respiratorias (CIBERES), Instituto Salud Carlos III, Madrid, Spain.

: Scarce evidence verifying the clinical impact of baloxavir on influenza complications is found.: PubMed, Cochrane Library, and Web of Science databases were searched through December 2020. Randomized-controlled trials (RCT) that enrolled patients with laboratory-confirmed influenza receiving neuraminidase inhibitors (NAI) or baloxavir comparing to placebo were assessed. Read More

View Article and Full-Text PDF

Impact of Asynchronous Electronic Communication-Based Visits on Clinical Outcomes and Health Care Delivery: Systematic Review.

J Med Internet Res 2021 05 5;23(5):e27531. Epub 2021 May 5.

Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, United States.

Background: Electronic visits (e-visits) involve asynchronous communication between clinicians and patients through a secure web-based platform, such as a patient portal, to elicit symptoms and determine a diagnosis and treatment plan. E-visits are now reimbursable through Medicare due to the COVID-19 pandemic. The state of evidence regarding e-visits, such as the impact on clinical outcomes and health care delivery, is unclear. Read More

View Article and Full-Text PDF

Study on the effects of desloratadine citrate disodium on the postoperative complications and inflammatory response in patients with chronic sinusitis undergoing endoscopic sinus surgery.

Am J Transl Res 2021 15;13(3):1840-1846. Epub 2021 Mar 15.

Department of Otolaryngology, The First Affiliated Hospital of Anhui Medical University Hefei 238000, Anhui Province, China.

Objective: To explore the effects of desloratadine citrate disodium on the postoperative complications and inflammatory markers in patients with chronic sinusitis undergoing endoscopic sinus surgery.

Methods: From June 2019 to December 2020, the patients with chronic sinusitis who received treatment in our hospital were selected and divided into the control group (CG) and experimental group (EG). In both groups, patients were given endoscopic sinus surgery. Read More

View Article and Full-Text PDF

Pre-intervention SNOT-22 scores predict outcomes in aspirin exacerbated respiratory disease.

Am J Otolaryngol 2021 Mar 31;42(5):103025. Epub 2021 Mar 31.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, United States of America.

Purpose: This study evaluated whether stratified preoperative, pre- aspirin desensitization (AD) sinonasal symptom scores predict postoperative, post-AD outcomes in Aspirin exacerbated respiratory disease (AERD).

Materials And Methods: Retrospective chart review of patients with aspirin challenge-proven AERD who underwent endoscopic sinus surgery followed by AD was performed. Preoperative, postoperative/pre-AD, and postoperative/post-AD sinonasal symptom scores were collected (22-item Sino-Nasal Outcomes Test, SNOT-22). Read More

View Article and Full-Text PDF

Post coronavirus disease mucormycosis: a deadly addition to the pandemic spectrum.

J Laryngol Otol 2021 Apr 8:1-6. Epub 2021 Apr 8.

Department of Otorhinolaryngology and Head Neck Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India.

Objective: To study the possible association between invasive fungal sinusitis (mucormycosis) and coronavirus disease.

Methods: A prospective observational study was conducted at a tertiary care centre over four months, involving all patients with mucormycosis of the paranasal sinuses suffering from or having a history of coronavirus disease infection.

Results: Twenty-three patients presented with mucormycosis, all had an association with coronavirus disease 2019. Read More

View Article and Full-Text PDF

Orbital abscess due to infection of a non-absorbable porous orbital implant after orbital wall fracture repair : An uncommon and delayed occurred case.

Eur J Ophthalmol 2021 Apr 5:11206721211008035. Epub 2021 Apr 5.

Department of Ophthalmology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

We report a rare case of a patient who developed an orbital abscess several years after successful orbital medial wall fracture repair. A 37-year-old female patient who underwent orbital fracture repair with a titanium Medpor orbital implant two years prior visited the clinic for pain, conjunctival injection, discharge, and lid swelling of the right eye. Orbital CT revealed severe orbital cellulitis and sinusitis. Read More

View Article and Full-Text PDF

Impact of a Social Marketing Intervention on General Practitioners' Antibiotic Prescribing Practices for Acute Respiratory Tract Complaints in Malta.

Antibiotics (Basel) 2021 Mar 31;10(4). Epub 2021 Mar 31.

Department of Global Public Health, Health Systems and Policy: Improving Use of Medicines, Karolinska Institutet, 171 77 Stockholm, Sweden.

Antibiotics are commonly prescribed in primary care for acute respiratory tract complaints (aRTCs), often inappropriately. Social marketing interventions could improve prescribing in such settings. We evaluate the impact of a social marketing intervention on general practitioners' (GPs') antibiotic prescribing for aRTCs in Malta. Read More

View Article and Full-Text PDF

Autoimmune Manifestations among Patients with Monogenic Inborn Errors of Immunity.

Pediatr Allergy Immunol 2021 Mar 27. Epub 2021 Mar 27.

Department of Pediatrics, Hamedan University of Medical Sciences, Hamedan, Iran.

Background: The inborn errors of immunity (IEIs) are a group of heterogeneous disorders mainly characterized by severe and recurrent infections besides other complications including autoimmune and inflammatory diseases. In this study, we aim to evaluate clinical, immunological, and molecular data of monogenic IEI patients with and without autoimmune manifestations.

Methods: We have retrospectively screened cases of monogenic IEI in the Iranian PID registry for the occurrence of autoimmunity and immune dysregulation. Read More

View Article and Full-Text PDF

How face masks influence the sinonasal quality of life during the COVID-19 pandemic.

Eur Arch Otorhinolaryngol 2021 Mar 27. Epub 2021 Mar 27.

Department of Otolaryngology and Head and Neck Surgery, The Chaim Sheba Medical Center, 52621, Tel-Hashomer, Israel.

Purpose: To study different mask types' impact on a sinonasal quality of life.

Methods: For this observational cross-sectional study, a web-based survey was distributed via social media forums. We used the validated Hebrew version of the Sinonasal Outcome Test-22 followed by a questionnaire developed specifically for the present study, focusing on the time of the COVID-19 pandemic (Mask Sinonasal Outcome Test), and questions regarding general health issues. Read More

View Article and Full-Text PDF

A policy of day-case sinonasal surgery is safe, well tolerated and cost-effective.

J Laryngol Otol 2021 Apr 26;135(4):341-343. Epub 2021 Mar 26.

Department of Otolaryngology, Waikato Hospital, Hamilton, New Zealand.

Objective: Practices vary regarding the timing of discharge after sinonasal surgery. This study aimed to examine the cost-effectiveness of same-day discharge compared to next-day discharge after sinonasal surgery.

Methods: A retrospective single-surgeon audit of sinonasal surgery over a 12-month period was performed. Read More

View Article and Full-Text PDF

Real-world evidence costs of allergic rhinitis and allergy immunotherapy in the commercially insured United States population.

Curr Med Res Opin 2021 Apr 2:1-15. Epub 2021 Apr 2.

ALK-Abelló, Hørsholm, Denmark.

Objective: To assess total and allergic rhinitis (AR)-related healthcare costs among AR patients residing in the United States with a focus on patients persisting with AIT.

Methods: AR patients were identified in the IBM MarketScan database between 1 January 2014 to 31 March 2017. Patients receiving allergy immunotherapy (AIT) were identified with relevant billing codes (earliest AIT claim = index date); non-AIT patients were identified with claims containing a diagnosis code for AR (earliest AR claim = index date). Read More

View Article and Full-Text PDF

Antibiotic Prescribing for Acute Respiratory Tract Infections During Telemedicine Visits Within a Pediatric Primary Care Network.

Acad Pediatr 2021 Mar 16. Epub 2021 Mar 16.

Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pa.

Objective: Regulatory and payment changes associated with COVID-19 facilitated wide-spread use of telehealth within pediatric primary care starting in March 2020. Given prior quality concerns about antibiotic management for children during telemedicine visits outside of primary care, we sought to examine acute respiratory tract infection (ARTI) visit volume and antibiotic management for children via telemedicine integrated within pediatric primary care.

Methods: Using electronic health record data from 47 practices within a large pediatric primary care network, we identified visits for ARTI from April to September 2020. Read More

View Article and Full-Text PDF

[Comparative efficacy of various treatment regimens for children 2-5 years old with symptoms of acute viral rhinosinusitis].

Vestn Otorinolaringol 2021 ;86(1):46-50

Perinatal Center, Khabarovsk, Russia.

In an open, randomized prospective comparative clinical study in parallel groups of patients with a diagnosis of acute respiratory infection, acute rhinosinusitis, 107 children aged 4-5 years took part. The purpose of this study was to compare the effectiveness of various treatment regimens for acute viral rhinosinusitis in children. We compared the treatment effectiveness of acute viral rhinosinusitis using the herbal medicine Sinupret in the form of oral drops, standard treatment and standard treatment supplemented with topical antibacterial drugs. Read More

View Article and Full-Text PDF

Factors influencing the sinus membrane thickness in edentulous regions: a cone-beam computed tomography study.

Int J Implant Dent 2021 Mar 2;7(1):16. Epub 2021 Mar 2.

Tokyo Medical and Dental University Dental Hospital, Tokyo Medical and Dental University, Tokyo, Japan.

Background: During implant treatment in the maxillary molar area, maxillary sinus floor augmentation is often performed to ameliorate the reduced alveolar bone height attributable to bone remodeling and pneumatization-induced expansion of the maxillary sinus. However, this augmentation may cause complications such as misplaced implants, artery damage, and maxillary sinus mucosal perforation; infections like maxillary sinusitis; and postsurgical complications such as bone graft leakage and postoperative nasal hemorrhaging. To reduce the complications during maxillary sinus floor augmentation and postoperative infections, we performed retrospective investigations of various systemic and local factors that influence pre-operative sinus mucosal thickness (SMT) by using cone-beam computed tomography (CBCT). Read More

View Article and Full-Text PDF

Full arch rehabilitation in patients with atrophic upper jaws with zygomatic implants: a systematic review.

Int J Implant Dent 2021 Feb 26;7(1):17. Epub 2021 Feb 26.

Department of Implantology, ILAPEO College, Curitiba, PR, Brazil.

Background: The main objective of this systematic review was to present the outcomes of the treatment with zygomatic implants (ZIs) in the rehabilitations of atrophic upper jaw.

Findings: An electronic database search in PubMed, along with a manual search, taking into account language and study period, was performed by two observers; any type of clinical trial and series that included the use of ZIs was used. In the search strategy, the following search terms were used: zygom* AND dental (Implant OR implants) AND edentulous NOT (biomechanic* OR finite element) NOT cadaver. Read More

View Article and Full-Text PDF
February 2021

A Value-Based Comparison of the Management of Ambulatory Respiratory Diseases in Walk-in Clinics, Primary Care Practices, and Emergency Departments: Protocol for a Multicenter Prospective Cohort Study.

JMIR Res Protoc 2021 Feb 22;10(2):e25619. Epub 2021 Feb 22.

Axe Santé des populations et Pratiques optimales en santé, Centre de recherche du CHU de Québec-Université Laval, Québec, QC, Canada.

Background: In Canada, 30%-60% of patients presenting to emergency departments are ambulatory. This category has been labeled as a source of emergency department overuse. Acting on the presumption that primary care practices and walk-in clinics offer equivalent care at a lower cost, governments have invested massively in improving access to these alternative settings in the hope that patients would present there instead when possible, thereby reducing the load on emergency departments. Read More

View Article and Full-Text PDF
February 2021

Odontogenic sinusitis publication trends from 1990 to 2019: a systematic review.

Eur Arch Otorhinolaryngol 2021 Feb 20. Epub 2021 Feb 20.

Department of Otolaryngology, Henry Ford Hospital, Detroit, MI, 48202, USA.

Purpose: Odontogenic sinusitis (ODS) is underrepresented in the literature compared to other forms of rhinosinusitis, specifically in sinusitis guidelines and position statements. ODS publication characteristics could help explain why ODS has received less attention in sinusitis guidelines and position statements. The purpose of this study was to explore trends in the quantity and quality of ODS studies over 3 decades from 1990 to 2019. Read More

View Article and Full-Text PDF
February 2021

[The expression of Notch pathway in nasal polyps and its correlation with the decreased Treg percentage and eosinophil infiltration].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Feb 3;56(2):124-132. Epub 2021 Feb 3.

Department of Otorhinolaryngology Head and Neck Surgery, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.

To investigate the correlation between Notch pathway expression in nasal polyps and Treg percentage and Eos infiltration. Patients with chronic sinusitis and simple nasal septum deviation who received nasal endoscopic surgery in the Third Affiliated Hospital of Sun Yat-Sen University between November 2012 and August 2018 were selected and enrolled in CRS group and control group respectively. Nasal mucosa tissues were collected from 30 CRSsNP patients (14 males and 16 females aged from 18 to 63), 58 CRSwNP patients (38 males and 20 females aged from 18 to 65) and 29 patients (19 males and 10 females aged from 20 to 57), who underwent nasal endoscopic surgery for correction of simple nasal septum deviation. Read More

View Article and Full-Text PDF
February 2021

Acute Invasive Fungal Sinusitis: A 30-Year Review of Pathology Practice and Possible Utility of the DiffQuik® Stain.

Head Neck Pathol 2021 Feb 5. Epub 2021 Feb 5.

Department of Pathology & Immunology, Washington University School of Medicine-Barnes Jewish Hospital, St. Louis, MO, USA.

Acute invasive fungal rhinosinusitis (AIFRS) is a fulminant disease with a high mortality rate. Here, we review the clinical and pathologic features of AIFRS over a 30-year period at a tertiary-care academic center focusing on diagnostic practice, especially the use of intra-operative consultation (IOC). A 1-year trial of intraoperative staining with DiffQuik® (DQ) was also assessed. Read More

View Article and Full-Text PDF
February 2021

[The influence of contoured sinus endoscopy on the recurrence of nasal polyps].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Feb;35(2):155-159

Department of Otolaryngology Head and Neck Surgery,the First Center Hospital,Institute of Otolaryngology of Tianjin,Key Clinical Discipline of Otolaryngology,Tianjin,300192,China.

The aim of this stusy is to study the effect of endoscopic surgery quality on the recurrence of nasal polyps. A total of 32 patients(64 sides) with recurrent nasal polyps were collected from December 2016 to June 2018, all of which were bilateral type Ⅱ diffuse nasal polyps in stage 3. According to the post-operative pathological results, patients were divided into eosinophilic nasal polyps group(EOS) and non-eosinophilic nasal polyps group(NEOS). Read More

View Article and Full-Text PDF
February 2021

[The expression and significance of TET gene and 5hmC in chronic rhinosinusitis].

Chong Yao Yu Xu

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 01;35(1):52-56

Department of Otolaryngology Head and Neck Surgery,Renmin Hospital of Wuhan University,Wuhan,430061,China.

To investigate the expression and clinical significance of TET gene and 5hmC in chronic sinusitis. Acquiring 20 cases of nasal polyps from chronic sinusitis with polyps(CW), 20 cases of uncinate process tissues from chronic sinusitis without polyps(CS), 10 cases of middle turbinate tissues from patients with nasal septum deviated as normal group(N).The expression of TET gene and 5hmC in chronic sinusitis was measured by immunofluorescence, Western-Blot and Quantitative real-time PCR. Read More

View Article and Full-Text PDF
January 2021

[The observation and evaluation of curative effect of nasal mucosa dryness, hemorrhae and erosion].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 01;35(1):29-33

Department of Otolaryngology Head and Neck Surgery,Xiamen Humanity Hospital,Fujian Medical University,Xiamen,361009,China.

To observe the curative effects of four kinds of plant extracts nasal spray mixture (myrtle oil, hyaluronic acid, fucoidan, anthocyanin) on 161 patients with nasal mucosa dryness, hemorrhae and erosion. ① Diagnosis: patients with nasal dryness, erosive and hemorrhae nasal septum mucosa confirmed by patients' complaints and nasal endoscopic test; ② Evaluation: the severity of subjective symptoms was evaluated by VAS score method from 0 to 10 points; the degree of mucosal lesions was divided into 0-8 points by nasal endoscopic test. ③ Intranasal Intranasal administration: 2 times per-day with 2 sprays on each side of the nasal cavity, and no less than 6-8 weeks. Read More

View Article and Full-Text PDF
January 2021

Patient satisfaction with telemedicine in rhinology during the COVID-19 pandemic.

Am J Otolaryngol 2021 May-Jun;42(3):102921. Epub 2021 Jan 9.

Case Western Reserve University School of Medicine, Cleveland, OH 44106; University Hospitals Cleveland Medical Center, Cleveland, OH 44106. Electronic address:

Background: The COVID-19 pandemic has forced the rapid integration of telemedicine services across several specialties, especially in Otolaryngology where risk of transmission is very high. Studies before and during the COVID-19 pandemic have shown that Otolaryngology is generally amenable to telemedicine. However, few studies have assessed patient satisfaction with telemedicine during the COVID-19 pandemic, and fewer have focused on patient satisfaction with telehealth in Rhinology. Read More

View Article and Full-Text PDF