67 results match your criteria single-examination risk


Single-Examination Risk Prediction of Severe Retinopathy of Prematurity.

Pediatrics 2021 Dec;148(6)

Departments of Ophthalmology.

Background And Objectives: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. Screening and treatment reduces this risk, but requires multiple examinations of infants, most of whom will not develop severe disease. Previous work has suggested that artificial intelligence may be able to detect incident severe disease (treatment-requiring retinopathy of prematurity [TR-ROP]) before clinical diagnosis. Read More

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December 2021

Association of Estimated Cardiorespiratory Fitness in Midlife With Cardiometabolic Outcomes and Mortality.

JAMA Netw Open 2021 Oct 1;4(10):e2131284. Epub 2021 Oct 1.

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts.

Importance: The associations of estimated cardiorespiratory fitness (eCRF) during midlife with subclinical atherosclerosis, arterial stiffness, incident cardiometabolic disease, and mortality are not well understood.

Objective: To examine associations of midlife eCRF with subclinical atherosclerosis, arterial stiffness, incident cardiometabolic disease, and mortality.

Design, Setting, And Participants: This cohort study included 2962 participants in the Framingham Study Second Generation (conducted between 1979 and 2001). Read More

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October 2021

CT Pulmonary Angiography for Risk Stratification of Patients with Nonmassive Acute Pulmonary Embolism.

Radiol Cardiothorac Imaging 2020 Aug 27;2(4):e190188. Epub 2020 Aug 27.

Cardiothoracic and Vascular Division, Department of Diagnostic and Interventional Radiology (D.C.R., A.M.J., S.D.Q.) and EEG Brain Mapping Core, Centre for Biomedical Imaging (CIBM) and Laboratory for Investigative Neurophysiology (The LINE), Department of Radiology (J.F.K.), Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland; Faculty of Biology and Medicine (FBM), University of Lausanne (UNIL), Lausanne, Switzerland (D.C.R., J.F.K., S.D.Q.); and Imagerive Diagnostic Radiology Institute, Geneva, Switzerland (G.A.).

Purpose: To investigate the prognostic value of an integrative approach combining clinical variables and the Qanadli CT obstruction index (CTOI) in patients with nonmassive acute pulmonary embolism (PE).

Materials And Methods: This retrospective study included 705 consecutive patients (mean age, 63 years; range, 18-95 years) with proven PE. Clot burden was quantified using the CTOI, which reflects the ratio of fully or partially obstructed pulmonary arteries to normal arteries. Read More

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Multiparametric exercise stress cardiovascular magnetic resonance in the diagnosis of coronary artery disease: the EMPIRE trial.

J Cardiovasc Magn Reson 2021 03 4;23(1):17. Epub 2021 Mar 4.

National Heart Research Institute Singapore, National Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.

Background: Stress cardiovascular magnetic resonance (CMR) offers assessment of ventricular function, myocardial perfusion and viability in a single examination to detect coronary artery disease (CAD). We developed an in-scanner exercise stress CMR (ExCMR) protocol using supine cycle ergometer and aimed to examine the diagnostic value of a multiparametric approach in patients with suspected CAD, compared with invasive fractional flow reserve (FFR) as the reference gold standard.

Methods: In this single-centre prospective study, patients who had symptoms of angina and at least one cardiovascular disease risk factor underwent both ExCMR and invasive angiography with FFR. Read More

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Prevalence, growth rate and complications of splenic artery aneurysms in chronic liver disease patients.

Vasa 2021 Feb 29;50(2):139-144. Epub 2020 Oct 29.

Hospital Israelita Albert Einstein, São Paulo, Brazil.

: Chronic liver disease (CLD) patients are at greater risk for developing splenic artery aneurysm (SAA). Treatment for aneurysms > 2.5 cm in this population is considered. Read More

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February 2021

Role of Cardiac Magnetic Resonance to Improve Risk Prediction Following Acute ST-Elevation Myocardial Infarction.

J Clin Med 2020 Apr 7;9(4). Epub 2020 Apr 7.

University Clinic of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstraße 35, A-6020 Innsbruck, Austria.

Cardiac magnetic resonance (CMR) imaging allows comprehensive assessment of myocardial function and tissue characterization in a single examination after acute ST-elevation myocardial infarction. Markers of myocardial infarct severity determined by CMR imaging, especially infarct size and microvascular obstruction, strongly predict recurrent cardiovascular events and mortality. The prognostic information provided by a comprehensive CMR analysis is incremental to conventional risk factors including left ventricular ejection fraction. Read More

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CMR based measurement of aortic stiffness, epicardial fat, left ventricular myocardial strain and fibrosis in hypertensive patients.

Int J Cardiol Heart Vasc 2020 Apr 12;27:100477. Epub 2020 Feb 12.

Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.

Introduction: A combined assessment of different parameters of cardiovascular (CV) risk and prognosis can be supportive and performed with cardiac magnetic resonance (CMR). Aortic stiffness, epicardial fat volume (EFV), left ventricular (LV) strain and fibrosis were evaluated within a single CMR examination and results were related to the presence of hypertension (HTN) and diabetes mellitus (DM).

Methods: 20 healthy controls (57. Read More

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Cardiac magnetic resonance imaging to detect ischemia in chronic coronary syndromes: state of the art.

Kardiol Pol 2019 Dec 13;77(12):1123-1133. Epub 2019 Nov 13.

Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.

The new 2019 European Society of Cardiology guidelines for the diagnosis and management of chronic coronary syndromes emphasize the role of noninvasive functional imaging of myocardial ischemia in diagnosing coronary artery disease to guide decision making regarding revascularization. Cardiac magnetic resonance imaging (CMR) stands out relative to other imaging modalities given its high safety profile, absence of ionizing radiation, and its versatility in encoding various image contrasts. It also allows an assessment of myocardial function, ischemia, and viability as well as permits tissue characterization including detection of edema in a single examination. Read More

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December 2019

FDG PET/CT as a survival prognostic factor in patients with advanced renal cell carcinoma.

Clin Exp Med 2019 Feb 28;19(1):143-148. Epub 2018 Nov 28.

Department of Oncology, Radiotherapy and Gynecologic Oncology, Faculty of Health Sciences, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.

Accurate prediction of the outcome of molecular target-based treatment in advanced renal cell carcinoma (RCC) is an important clinical problem. Positron emission tomography/computed tomography using [18F]-2-fluoro-2-deoxyglucose (FDG PET/CT) is a noninvasive tool for the assessment of glucose accumulation which can be a marker of the biological characteristics of the tumor. In this paper, we assess FDG PET/CT as a survival prognostic marker in patients with advanced RCC. Read More

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February 2019

A PET/MR Imaging Approach for the Integrated Assessment of Chemotherapy-induced Brain, Heart, and Bone Injuries in Pediatric Cancer Survivors: A Pilot Study.

Radiology 2017 12 4;285(3):971-979. Epub 2017 Aug 4.

From the Department of Radiology and the Molecular Imaging Program (A.J.T., A.I., A.M., J.T., P.G., C.K., K.W.Y., M.M., F.C., H.E.D.L.), Department of Pediatrics, Division of Pediatric Hematology/Oncology (S.L.F., K.M.S., H.E.D.L.), and Department of Medicine, Division of Cardiology (P.Y.), Lucile Packard Children's Hospital, Stanford University School of Medicine, 725 Welch Rd, Stanford, CA 94305-5654.

Purpose To develop a positron emission tomography (PET)/magnetic resonance (MR) imaging protocol for evaluation of the brain, heart, and joints of pediatric cancer survivors for chemotherapy-induced injuries in one session. Materials and Methods Three teams of experts in neuroimaging, cardiac imaging, and bone imaging were tasked to develop a 20-30-minute PET/MR imaging protocol for detection of chemotherapy-induced tissue injuries of the brain, heart, and bone. In an institutional review board-approved, HIPAA-compliant, prospective study from April to July 2016, 10 pediatric cancer survivors who completed chemotherapy underwent imaging of the brain, heart, and bone with a 3-T PET/MR imager. Read More

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December 2017

Impact of postoperative pulmonary hypertension on outcome after heart transplantation.

Scand Cardiovasc J 2017 Jun 22;51(3):172-181. Epub 2017 Mar 22.

a Department of Clinical Sciences Lund, Cardiology , Lund University , Lund , Sweden.

Objectives: We wanted to investigate the effects of postoperative pulmonary hypertension (PH: mean pulmonary artery pressure [MPAP] ≥ 25 mmHg), diastolic pressure gradient (DPG), pulmonary vascular resistance (PVR), and repeated hemodynamic measurements on long-term survival after heart transplantation (HT).

Design: Eighty-nine patients who underwent HT at Skåne University Hospital in Lund in the period 1988-2010 and who were evaluated with right-heart-catheterization at rest, prior to HT and repeatedly during the first postoperative year, were grouped based on their MPAP, DPG, and PVR.

Results: One year after HT, survival was lower in patients with PH than in those without, in patients with DPG ≥7 mmHg than in those with DPG <7 mmHg, and in patients with PVR >3 WU than in those with PVR ≤3 WU. Read More

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Patient-specific Hip Fracture Strength Assessment with Microstructural MR Imaging-based Finite Element Modeling.

Radiology 2017 06 2;283(3):854-861. Epub 2016 Dec 2.

From the Departments of Radiology (C.S.R., B.T.N., E.A.K., R.M.) and Orthopaedic Surgery (C.S.R.), University of Pennsylvania, 3400 Spruce St, 1 Founders Building, Philadelphia, PA 19104; and Department of Radiology, Center for Biomedical Imaging (A.H., G.C.), Department of Orthopaedic Surgery, Hospital for Joint Diseases (A.R., S.V.), and Osteoporosis Center, Hospital for Joint Diseases (S.H.), NYU Langone Medical Center, New York, NY.

Purpose To describe a nonlinear finite element analysis method by using magnetic resonance (MR) images for the assessment of the mechanical competence of the hip and to demonstrate the reproducibility of the tool. Materials and Methods This prospective study received institutional review board approval and fully complied with HIPAA regulations for patient data. Written informed consent was obtained from all subjects. Read More

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Infectious Diseases of the Heart: Pathophysiology, Clinical and Imaging Overview.

Radiographics 2016 Jul-Aug;36(4):963-83

From the Division of Medical Imaging, Sutter Medical Group, 1500 Expo Pkwy, Sacramento, CA 95815 (H.M.); Department of Radiology (C.S.R., A.J.B.), Division of Cardiology (J.A.M.), and Department of Pathology (R.L.R.), University of Texas Health Science Center at San Antonio, San Antonio, Tex; Department of Radiology, University of Colorado Anschutz Medical Center, Aurora, Colo (D.V.); Department of Radiology, University of Texas Health Science Center at Houston, Houston, Tex (D.O.); and Department of Radiology, Saint Luke's Health System, Kansas City, Mo (S.M.).

Myriad infectious organisms can infect the endocardium, myocardium, and pericardium, including bacteria, fungi, parasites, and viruses. Significant cardiac infections are rare in the general population but are associated with high morbidity and mortality as well as increased risk in certain populations, such as the elderly, those undergoing cardiac instrumentation, and intravenous drug abusers. Diagnostic imaging of cardiac infections plays an important role despite its variable sensitivity and specificity, which are due in part to the nonspecific manifestations of the central inflammatory process of infection and the time of onset with respect to the time of imaging. Read More

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Whole body cardiovascular magnetic resonance imaging to stratify symptomatic and asymptomatic atherosclerotic burden in patients with isolated cardiovascular disease.

BMC Med Imaging 2016 Feb 29;16:18. Epub 2016 Feb 29.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, ᅟ, DD1 9SY, UK.

Background: The aim of this study was to use whole body cardiovascular magnetic resonance imaging (WB CVMR) to assess the heart and arterial network in a single examination, so as to describe the burden of atherosclerosis and subclinical disease in participants with symptomatic single site vascular disease.

Methods: 64 patients with a history of symptomatic single site vascular disease (38 coronary artery disease (CAD), 9 cerebrovascular disease, 17 peripheral arterial disease (PAD)) underwent whole body angiogram and cardiac MR in a 3 T scanner. The arterial tree was subdivided into 31 segments and each scored according to the degree of stenosis. Read More

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February 2016

Transbronchial needle aspirations vs. percutaneous needle aspirations.

J Thorac Dis 2015 Dec;7(Suppl 4):S300-3

1 Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Pulmonary Diseases Unit, Department of Internal Medicine, Azienda Ospedali Riuniti, Ancona, Italy ; 2 Division of Pulmonary and Critical Care Medicine, Johns Hopkins Hospital, Sheikh Zayed Cardiovascular and Critical Care Tower, Baltimore, USA.

Over the last decade, the increasing diffusion of innovative and more powerful imaging guided techniques has further broadened the bronchoscopist's horizons in the diagnostic work-up of peripheral pulmonary nodules/masses (PPN/M). However, in most of institutions worldwide, due to the lack of resources and specific skills, the routinely diagnostic approach to PPN/M is still represented by imaging-guided transbronchial needle aspirations (TBNA) and percutaneous needle aspirations (PCNA). So far, no randomized clinical trials directly comparing the accuracy of the two procedures are available, and a standardized strategy that defines the proper role of each technique has yet to be established. Read More

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December 2015

Vascular Imaging Before Transcatheter Aortic Valve Replacement (TAVR): Why and How?

Curr Cardiol Rep 2016 Feb;18(2):14

Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC, 29425, USA.

Transcatheter aortic valve replacement (TAVR) has become an alternative to surgical intervention for symptomatic or severe aortic valve stenosis in patients with high surgical risk. Successful TAVR requires a multimodality imaging approach for appropriate patient selection and prosthesis sizing. Here, we describe individual imaging modalities and report their respective roles in this emerging field. Read More

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February 2016

Lower Extremity Overuse Conditions Affecting Figure Skaters During Daily Training.

Orthop J Sports Med 2015 Jul 28;3(7):2325967115596517. Epub 2015 Jul 28.

Department of Neurology and Center for Neuroscience, University of California-Davis, Davis, California, USA.

Background: Most ice figure skaters train and compete with ongoing issues in the lower extremities, which are often overlooked by the skaters and considered injuries only when they prevent the athletes from skating. Although not severe, these conditions impair the quality of daily training and compromise the skaters' state of mind and performances.

Purpose: (1) To determine the point prevalence of the ongoing lower extremity overuse conditions in a population of ice figure skaters of all ages and levels and (2) to identify the risk factors contributing to the development of the most common ongoing conditions. Read More

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PET/CT with (11)C-choline for evaluation of prostate cancer patients with biochemical recurrence: meta-analysis and critical review of available data.

Eur J Nucl Med Mol Imaging 2016 Jan 9;43(1):55-69. Epub 2015 Oct 9.

Nuclear Medicine, Humanitas Research Hospital, Via A. Manzoni 56, 20089, Rozzano, Milano, Italy.

Purpose: For the last decade PET and PET/CT with (11)C-choline have been proposed for the evaluation of prostate cancer (PC), but the diagnostic performance of (11)C-choline PET/CT is still a matter of debate. We performed a comprehensive review of the most important clinical application of (11)C-choline PET, restaging of patients with biochemical relapse, following a rigorous methodological approach and including assessment of the risk of bias. We conducted a systematic review and meta-analysis of the literature assessing (11)C-choline PET/CT for its accuracy in the diagnosis and ability to detect the site of recurrence of PC in the restaging of patients with biochemical recurrence after initial treatment with curative intent. Read More

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January 2016

Management of Incidental Pancreatic Cystic Lesions.

Viszeralmedizin 2015 Feb;31(1):14-24

Department of Internal Medicine, DRK Kliniken Berlin - Köpenick, Berlin, Germany.

Background: Pancreatic cystic lesions (PCL) are common. They are increasingly detected as an incidental finding of transabdominal ultrasound or cross-sectional imaging. In contrast to other parenchymal organs, dysontogenetic pancreatic cysts are extremely rare. Read More

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February 2015

Technical assessment of whole body angiography and cardiac function within a single MRI examination.

Clin Radiol 2015 Jun 16;70(6):595-603. Epub 2015 Mar 16.

NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee DD1 9SY, UK; Medical Research Institute, College of Medicine, University of Dundee, Dundee DD1 9SY, UK.

Aim: To evaluate a combined protocol for simultaneous cardiac MRI (CMR) and contrast-enhanced (CE) whole-body MR angiography (WB-MRA) techniques within a single examination.

Materials And Methods: Asymptomatic volunteers (n = 48) with low-moderate risk of cardiovascular disease (CVD) were recruited. The protocol was divided into four sections: (1) CMR of left ventricle (LV) structure and function; (2) CE-MRA of the head, neck, and thorax followed by the distal lower limbs; (3) CMR LV "late gadolinium enhancement" assessment; and (4) CE-MRA of the abdomen and pelvis followed by the proximal lower limbs. Read More

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Thoracic manifestation of Eisenmenger's syndrome in adult patients: a MDCT review.

Lung 2015 Apr 31;193(2):173-81. Epub 2014 Dec 31.

Cardio-Thoracic Radiology Unit, Cardio-Thoracic-Vascular Department, University Hospital S. Orsola-Malpighi, via Massarenti 9, 40100, Bologna, Italy,

Eisenmenger's syndrome (ES) is the most advanced form of pulmonary arterial hypertension (PAH) associated with congenital heart diseases (CHD). It is caused by simple or complex CHD with a large systemic-to-pulmonary shunt. When the pulmonary pressure exceeds the systemic pressure, the shunt reverses and central cyanosis appears. Read More

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Magnetic resonance enterography in evaluation and management of children with Crohn's disease.

Semin Ultrasound CT MR 2014 Aug 2;35(4):331-48. Epub 2014 Jun 2.

Department of Radiology, Baystate Medical Center, Springfield, MA.

The role of radiologic evaluation in Crohn's disease (CD) has undergone a recent paradigm shift in which the radiologist adds value to the multidisciplinary team by longitudinally assessing therapeutic response and identifying treatment-modifying subtypes, such as fibrostenotic or fistulizing disease. Magnetic resonance enterography (MRE) has become the primary imaging modality used. The combination of multiplanar, multiparametric, and multiphasic contrast-enhanced imaging with the high spatial resolution and very high tissue contrast of MR imaging allows for detailed evaluation of intra-abdominal pathology, without the risk of cumulative radiation exposure. Read More

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Imaging of solitary pulmonary nodule-a clinical review.

Quant Imaging Med Surg 2013 Dec;3(6):316-26

West of Scotland PET Centre, Beatson Oncology Centre, Gartnavel General Hospital, Glasgow G12 0YN, UK.

Current widespread use of cross-sectional imaging has led to exponential rise in detection of solitary pulmonary nodules (SPNs). Whilst large numbers of these are benign 'incidentalomas', lung cancers presenting as SPNs are often early disease, which have good prognosis. Therefore, there is rising demand and expectation for more accurate, non-invasive, diagnostic tests to characterize SPNs, aiming to avoid missed or delayed diagnosis of lung cancer. Read More

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December 2013

Myopia and glaucoma: diagnostic and therapeutic challenges.

Curr Opin Ophthalmol 2013 Mar;24(2):96-101

Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA 94303, USA.

Purpose Of Review: There is strong epidemiologic evidence linking myopia with glaucomatous disease, but a myopic optic nerve can pose significant challenges with regard to making the correct diagnosis of glaucoma. This review provides an overview of these diagnostic and therapeutic challenges with a particular focus on how the growing prevalence of myopia among specific populations may impact such therapy.

Recent Findings: For a given individual, the link between myopia and glaucoma remains murky in many circumstances, largely because of the fact that it is difficult to separate out myopia-related structural and functional abnormalities from 'true' glaucomatous changes. Read More

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National survey of radiation doses of pediatric chest radiography in Korea: analysis of the factors affecting radiation doses.

Korean J Radiol 2012 Sep-Oct;13(5):610-7. Epub 2012 Aug 28.

Department of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea.

Objective: To investigate radiation doses in pediatric chest radiography in a national survey and to analyze the factors that affect radiation doses.

Materials And Methods: The study was based on the results of 149 chest radiography machines in 135 hospitals nationwide. For each machine, a chest radiograph was obtained by using a phantom representing a 5-year-old child (ATOM® dosimetry phantom, model 705-D, CIRS, Norfolk, VA, USA) with each hospital's own protocol. Read More

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Combined PET/CT for IMRT treatment planning of NSCLC: contrast-enhanced CT images for Monte Carlo dose calculation.

Phys Med 2013 Nov 10;29(6):644-9. Epub 2012 Sep 10.

Section for Biomedical Physics, University Hospital for Radiation Oncology, Eberhard-Karls-University Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany. Electronic address:

Purpose: Combined PET/CT imaging has been proposed as an integral part of radiotherapy treatment planning (TP). Contrast-enhanced CT (ceCT) images are frequently acquired as part of the PET/CT examination to support target delineation. The aim of this dosimetric planning study was to investigate the error introduced by using a ceCT for intensity modulated radiotherapy (IMRT) TP with Monte Carlo dose calculation for non-small cell lung cancer (NSCLC). Read More

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November 2013

Measuring myocardial salvage.

Cardiovasc Res 2012 May 5;94(2):266-75. Epub 2012 Feb 5.

Department of Cardiology, Aarhus University Hospital Skejby, Aarhus N, Denmark.

The efficacy of cardioprotective strategies can be quantified by myocardial salvage as an indicator of therapeutic benefit. Salvage is calculated as the difference between the area at risk (AAR) and the final infarct size (FIS). AAR has been quantified by angiographic assessment followed by quantification of FIS by biochemical ischaemic markers or imaging modalities such as cardiovascular magnetic resonance (CMR). Read More

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Mallampati test as a predictor of laryngoscopic view.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2010 Dec;154(4):339-43

Department of Anesthesiology and Resuscitation, University Hospital Olomouc, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.

Aim: To determine the accuracy of the modified Mallampati test for predicting difficult tracheal intubation.

Design: A cross-sectional, clinical, observational, non-blinded study. A quality analysis of anesthetic care. Read More

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December 2010

Radiation safety in the neonatal intensive care unit: too little or too much concern?

Authors:
Cheng-Chung Yu

Pediatr Neonatol 2010 Dec;51(6):311-9

Department of Pediatrics, The Mennonite Christian Hospital, 44 Min-Chuan Road, Hualien, Taiwan.

With rising numbers of extremely premature infants in the neonatal intensive care unit (NICU) who require multiple radiologic examinations for their complex medical conditions, concerns the risk of radiation exposure become a more prevalent issue. The biological effects from cumulative doses of both primary and secondary radiation can be particularly troubling for very premature babies due to their inherent sensitivity to both iatrogenic and environmental insults. Similarly, radiologic studies performed in the NICU pose potentially significant exposure risks to caretakers and to the families of patients often present in the NICU during these examinations. Read More

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December 2010