1,432 results match your criteria sfa disease


Endovascular recanalization of chronic total occlusions of the native superficial femoral artery after failed femoropopliteal bypass in patients with critical limb ischemia.

CVIR Endovasc 2021 Sep 7;4(1):68. Epub 2021 Sep 7.

Radiology Division, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, University Hospital Mater Domini, Viale Europa, 88100, Catanzaro, Italy.

Background: Femoropopliteal bypass occlusions are a significant issue in patients with critical limb ischemia and chronic total occlusion of the native superficial femoral artery, which challenges vascular surgeons and interventional radiologists. Performing a secondary femoropopliteal bypass is still considered the standard of care, although it is associated with a higher complication rate and lower patency rate in comparison with primary bypass. Over the past few years, angioplasty has been commonly used, with the development in endovascular technologies, to treat chronic total occlusions of the native superficial femoral artery, with a good technical success rate and clinical prognosis. Read More

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September 2021

Macrophage Polarization as a Novel Therapeutic Target for Endovascular Intervention in Peripheral Artery Disease.

JACC Basic Transl Sci 2021 Aug 23;6(8):693-704. Epub 2021 Jul 23.

Chronic Diseases, School of Medical Sciences, Faculty of Health and Medicine, University of Sydney, Sydney, New South Wales, Australia.

Peripheral artery disease (PAD) has a significant impact on human health, affecting 200 million people globally. Advanced PAD severely diminishes quality of life, affecting mobility, and in its most severe form leads to limb amputation and death. Treatment of PAD is among the least effective of all endovascular procedures in terms of long-term efficacy. Read More

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Antegrade superficial femoral artery approach using manual compression and 4-F delivery system for infrainguinal occlusive disease.

Ann Vasc Surg 2021 Aug 27. Epub 2021 Aug 27.

Department of Vascular and Endovascular Surgery, Paris St. Joseph Hospital Group, 75014 Paris, France. Electronic address:

Objectives: This study sought to assess the feasibility and safety of antegrade superficial femoral artery (SFA) duplex-guided puncture using a 4-F catheter sheath and manual compression for the treatment of infrainguinal occlusive lesions.

Materials / Methods: From March 2017 to March 2019, all patients who underwent endovascular treatment employing an antegrade SFA approach for femoropopliteal or below-the-knee (BTK) lesions were included in this study. Follow-up included clinical and duplex ultrasound examinations at 1 mo. Read More

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Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet.

Nutrients 2021 Aug 21;13(8). Epub 2021 Aug 21.

GLUTEN3S Research Group, Department of Nutrition and Food Science, University of the Basque Country, 01006 Vitoria-Gasteiz, Spain.

Celiac disease (CD) is a chronic autoimmune disorder of the small intestine, whose only effective treatment is a gluten-free diet (GFD). It is characterized by the atrophy of the intestinal villi that leads to altered nutrient absorption. This study describes the nutritional imbalances which may be found in adults with CD following a GFD. Read More

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Associations of Dietary Fat Intake With Mortality From All Causes, Cardiovascular Disease, and Cancer: A Prospective Study.

Front Nutr 2021 9;8:701430. Epub 2021 Aug 9.

Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

The impact of fat intake on health has become a growing public concern. The existing evidence linking specific dietary fat intake with mortality is controversial. We aimed to investigate the association between fat intake and total and cause-specific mortality in the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial. Read More

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Associations between dietary fatty acid patterns and cognitive function in the Hispanic Community Health Study/Study of Latinos.

Br J Nutr 2021 Aug 26:1-35. Epub 2021 Aug 26.

Department of Agriculture Nutrition and Food Systems, University of New Hampshire.

Our objective was to quantify the cross-sectional associations between dietary fatty acid (DFA) patterns and cognitive function among Hispanic/Latino adults. This study included data from 8,942 participants of the Hispanic Community Health Study/Study of Latinos, a population-based cohort study (weighted age 56.2 y and proportion female 55. Read More

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Impact of Meal Fatty Acid Composition on Postprandial Lipemia in Metabolically Healthy Adults and Individuals with Cardiovascular Disease Risk Factors: A Systematic Review.

Adv Nutr 2021 Aug 24. Epub 2021 Aug 24.

Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.

Consuming fat results in postprandial lipemia, which is defined as an increase in blood triglyceride (TG) concentration. According to current knowledge, an excessively elevated postprandial TG concentration increases the risk of cardiovascular disease (CVD). It is well known that meal-dependent (e. Read More

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Feasibility of using the balloon backed-up microcatheter technique to treat superficial femoral artery occlusion under extra-vascular ultrasound guidance via radial access.

Cardiovasc Revasc Med 2021 Aug 16. Epub 2021 Aug 16.

Department of Cardiology, Saiseikai Yokohama City Eastern Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama City, Kanagawa 230-0012, Japan. Electronic address:

Background: Endovascular treatment (EVT) of superficial femoral artery (SFA) lesions that can be reached through transradial access (TRA) has often been performed due to its low invasiveness. For complex lesions such as chronic total occlusion (CTO) treated via TRA, EVT is still challenging due to poor device backup and guidewire operability. However, TRA might be preferred in patients with a high risk of bleeding or restricted access sites. Read More

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Lipid profile disturbances may predispose psoriatic patients to liver dysfunction.

Postepy Dermatol Alergol 2021 Apr 22;38(2):310-318. Epub 2021 May 22.

Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland.

Introduction: Psoriasis is a chronic inflammatory disease associated with metabolic disturbances and liver dysfunction. Both serum fatty acids (FA) and ceramides (Cer) have structural functions but also are signal molecules that could be involved in the pathogenesis of liver dysfunction.

Aim: To assess the concentration of the circulating FA and Cer in correlation with the alanine aminotransferase (ALT) blood level in psoriatic patients. Read More

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Single-flap versus double-flap approach for periodontal pocket reduction in supraosseous defects: a comparative study.

J Periodontal Implant Sci 2021 Aug;51(4):239-253

Department of Periodontics, Vishnu Dental College, Bhimavaram, India.

Purpose: The single-flap approach (SFA) is a minimally invasive technique with limited mucoperiosteal flap elevation to gain access to the buccal/palatal aspects, thus limiting post-surgical complications. The purpose of the present study was to gain insights into the impact of the SFA over the double-flap approach (DFA) on periodontal flap treatment outcomes and patient compliance in terms of discomfort and time taken for surgical procedures.

Methods: Twenty patients with persistent probing pocket depths of ≥5 mm were scheduled for the SFA (test site) and for the DFA (control site). Read More

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A rare case of spontaneous superficial femoral artery pseudoaneurysm in a young patient: case report and review of literature.

J Surg Case Rep 2021 Aug 10;2021(8):rjab327. Epub 2021 Aug 10.

Department of Cardiovascular and Thoracic Surgery, St Luc Hospital, Catholic University of Louvain, Brussels, Belgium.

Spontaneous femoral artery pseudoaneurysm (PSA) is a rare disease and there are few reported cases. We report a case of a 17-year-old male with increasing left leg pain associated with swelling at the site of the pain. We observed a voluminous pulsatile mass. Read More

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Are fatty acids associated with disease activity and biomarkers in patients with psoriatic arthritis? Data from a multicenter clinical trial.

Rheumatol Int 2021 Jul 29. Epub 2021 Jul 29.

Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

The pathogenesis of psoriatic arthritis (PsA) involves inflammation and bone and soft tissue turnover. Dietary fatty acids have previously been associated with pro-inflammatory effects induced by saturated fatty acids (SFA) and anti-inflammatory effects achieved by at least some polyunsaturated fatty acids (PUFA). The aim of the study was to investigate the correlations between the content of fatty acids in granulocytes and clinical and biochemical markers of PsA. Read More

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Aneurysmal Dilatation of the Superficial Femoral Artery After Endovascular Intervention.

JACC Case Rep 2021 Mar 17;3(3):425-426. Epub 2021 Mar 17.

Mount Sinai Heart, Mount Sinai Medical Center, New York, New York, USA.

A patient with occlusion of the left superficial femoral artery (SFA) underwent endovascular intervention. Six-month follow-up angiography revealed aneurysmal dilatation of the previously stented artery. This finding may be a result of maladaptive vascular remodeling or arterial injury resulting in aneurysmal dilatation secondary to subintimal crossing, atherectomy, and paclitaxel therapies. Read More

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Entrapped Crown of Orbital Atherectomy Device by Intimal Tissue Entanglement During Peripheral Intervention.

JACC Case Rep 2021 Mar 17;3(3):412-414. Epub 2021 Mar 17.

Department of Cardiology, UPMC Somerset Hospital, Somerset, Pennsylvania, USA.

Orbital atherectomy is a commonly used procedure for peripheral arterial disease. Crown entrapment is a rare but potentially dangerous complication of orbital atherectomy. We describe a case of crown entrapment by markedly excessive atheromatous intimal tissue attachment to the device and an innovative retrieval technique that may minimize vascular injury. Read More

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Metformin Affects Cardiac Arachidonic Acid Metabolism and Cardiac Lipid Metabolite Storage in a Prediabetic Rat Model.

Int J Mol Sci 2021 Jul 19;22(14). Epub 2021 Jul 19.

Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14021 Prague, Czech Republic.

Metformin can reduce cardiovascular risk independent of glycemic control. The mechanisms behind its non-glycemic benefits, which include decreased energy intake, lower blood pressure and improved lipid and fatty acid metabolism, are not fully understood. In our study, metformin treatment reduced myocardial accumulation of neutral lipids-triglycerides, cholesteryl esters and the lipotoxic intermediates-diacylglycerols and lysophosphatidylcholines in a prediabetic rat model ( < 0. Read More

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Angiographic flow velocity predicts lower limb outcomes after endovascular therapy: Application of the frame count method.

Vasc Med 2021 Jul 21:1358863X211025613. Epub 2021 Jul 21.

Cardiovascular Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

Introduction: Several factors related to lesion characteristics and endovascular therapy (EVT) procedures have been reported to affect primary patency after EVT. However, it is unknown why these factors were associated with primary patency. We hypothesized patency failure was related to poor blood flow in affected arteries. Read More

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Clinical outcome of drug-coated balloon versus scaffold device in patients with superficial femoral artery chronic total occlusion.

Heart Vessels 2021 Jul 19. Epub 2021 Jul 19.

Department of Cardiovascular Medicine, Asahi General Hospital, I-1326 Asahi, , Chiba, 289-2511, Japan.

The demand for endovascular therapy is increasing in an aging society, but the problem of restenosis in the chronic phase has not been resolved in femoropopliteal occlusive disease. Few studies have compared drug-coated balloon (DCB) and scaffold devices in chronic total occlusion (CTO) of the superficial femoral artery (SFA). This study aimed to compare DCBs with scaffold in patients with CTO of the SFA. Read More

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Analysis on the relationship between winter precipitation and the annual variation of horse stomach fly community in arid desert steppe, Northwest China (2007-2019).

Integr Zool 2021 Jul 13. Epub 2021 Jul 13.

Key Laboratory of Non-Invasive Research Technology for Endangered Species, School of Ecology and Nature Conservation, Beijing Forestry University, Beijing, China.

Gasterophilus spp. have been found to be widespread in reintroduced Przewalski's horses in the Kalamaili Nature Reserve (Northwest China). However, data on the annual variation in Gasterophilus infections are lacking. Read More

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Spontaneous Transection of the Superficial Femoral Artery with Devastating Outcomes: A Case Report.

Vasc Specialist Int 2021 Jul 12;37:22. Epub 2021 Jul 12.

University Vascular Surgical Unit, National Hospital of Colombo, Colombo, Sri Lanka.

Non-traumatic, simultaneous pseudoaneurysms of the bilateral superficial femoral arteries (SFAs) are extremely rare. Spontaneous transection of the SFA is another unique pathology. Here, we present a patient with end stage kidney disease who was diagnosed with bilateral, simultaneous SFA pseudoaneurysms. Read More

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Direct puncture of an occluded common femoral artery as a new approach for endovascular aortic aneurysm repair.

CVIR Endovasc 2021 Jul 10;4(1):58. Epub 2021 Jul 10.

Department of Cardiovascular Surgery, Kyoto Okamoto Memorial Hospital, 100 Nishinokuchi, Kumiyama, Kuse District, Kyoto, 613-0034, Japan.

Background: Abdominal aortic aneurysms (AAA) which present with a hostile access are not uncommon. When an arterial occlusion continuously involves from the iliac to the femoropopliteal artery, endovascular aneurysm repair (EVAR) can become complex, necessitating an adjunctive surgical procedure. The present report outlines a successful EVAR which was conducted without any adjunctive surgical procedure for an AAA complicated by extensive access vessel occlusion. Read More

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Successful Revascularization of Infrapopliteal Chronic Total Occlusions Using the Plantar Arch as a Conduit and Retrograde Pedal Access.

Ochsner J 2021 ;21(2):209-213

Department of Cardiology, Ochsner Clinic Foundation, Kenner, LA.

With the rising prevalence of critical limb ischemia (CLI), the pedal-plantar loop technique and retrograde access may be needed to increase interventional success. A 63-year-old female with severe peripheral artery disease presented with a 2-month nonhealing wound on the dorsum of her left foot despite wound care. We inserted a 65-cm Destination Guiding Sheath and crossed the right superficial femoral artery (SFA) chronic total occlusion (CTO) that we initially treated with a 4. Read More

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January 2021

The impact of percutaneous peripheral interventions on endothelial function.

Vasa 2021 Jul 8. Epub 2021 Jul 8.

Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University of Duisburg-Essen, Germany.

Treatment of symptomatic peripheral artery disease (PAD) through endovascular interventions is the primary revascularization strategy. Interventions restore perfusion but may cause severe injury to the vascular endothelium, which regulates vascular tone. Endothelial dysfunction is involved in the progression of cardiovascular disease, with higher incidences of vascular events. Read More

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W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34.

Mol Neurobiol 2021 Jul 5. Epub 2021 Jul 5.

Biochemistry & Molecular Biology, University of Oklahoma Health Sciences Center, 608 Stanton L. Young Blvd, DMEI 428PP, Oklahoma City, OK, 73104, USA.

Spinocerebellar ataxia (SCA) is a neurodegenerative disorder characterized by ataxia and cerebellar atrophy. A number of different mutations gives rise to different types of SCA with characteristic ages of onset, symptomatology, and rates of progression. SCA type 34 (SCA34) is caused by mutations in ELOVL4 (ELOngation of Very Long-chain fatty acids 4), a fatty acid elongase essential for biosynthesis of Very Long Chain Saturated and Polyunsaturated Fatty Acids (VLC-SFA and VLC-PUFA, resp. Read More

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A case report of successful stent implantation through a fractured stent-strut in a superficial femoral artery based on bench testing simulation.

Eur Heart J Case Rep 2021 Jul 1;5(7):ytab246. Epub 2021 Jul 1.

Cardiovascular Division, NHO Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, 540-0006, Japan.

Background: Stent implantation through the stent-strut of a previously implanted self-expandable stent in the superficial femoral artery (SFA) is not usually performed because the additional stent cannot dilate sufficiently. The key point to achieve sufficient expansion of an additional stent is to break the stent-strut of the previously implanted stent. However, there is no report of how to break the stent-strut. Read More

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Threshold Effects of Total Copper Intake on Cognitive Function in US Older Adults and the Moderating Effect of Fat and Saturated Fatty Acid Intake.

J Acad Nutr Diet 2021 Jul 1. Epub 2021 Jul 1.

Background: Evidence for a relationship between total copper intake and cognition is lacking, and few studies have assessed the moderating effect of dietary fat and saturated fatty acid (SFA) intake on this relationship.

Objective: Our aim was to explore the curvilinear association between total copper intake and cognitive function in older adults, and to clarify the moderating effect of dietary fat and SFA intake on the association.

Design: This was a cross-sectional analysis of data from National Health and Nutrition Examination Surveys 2011-2014. Read More

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The effect of various high-fat diet on liver histology in the development of NAFLD models in mice.

J Basic Clin Physiol Pharmacol 2021 Jun 25;32(4):547-553. Epub 2021 Jun 25.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Airlangga, Surabaya, Indonesia.

Objectives: Nonalcoholic fatty liver disease (NAFLD) is exceptionally common around the world. The development of NAFLD is increasing rapidly in the world, along with changes in lifestyle. Excess lipid intake is one of the risk factors for NAFLD. Read More

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Nutritional, Cardiovascular Health and Lifestyle Status of 'Health Conscious' Adult Vegans and Non-Vegans from Slovenia: A Cross-Sectional Self-Reported Survey.

Int J Environ Res Public Health 2021 06 2;18(11). Epub 2021 Jun 2.

Basics of Movements in Sport, Faculty of Sport, University of Ljubljana, 1000 Ljubljana, Slovenia.

The study aim was to investigate differences in nutritional, cardiovascular and lifestyle status of 'health conscious' subjects. In a partial 'lock-down' during the COVID-19 pandemic period, we performed a web-based, cross-sectional study. We compared 80 self-selected subjects (51 vegans, 67% females, and 29 non-vegans, 55% females, = 0. Read More

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Serum concentrations of SFAs and CDKAL1 single-nucleotide polymorphism rs7747752 are related to an increased risk of gestational diabetes mellitus.

Am J Clin Nutr 2021 Jun 30. Epub 2021 Jun 30.

Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.

Background: Interactions between genetic and nutritional factors can contribute to the risk of gestational diabetes mellitus (GDM).

Objectives: We aimed to explore the associations of cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1 (CDKAL1) single-nucleotide polymorphism (SNP) rs7747752 and serum concentrations of SFAs with the risk of GDM in Chinese women.

Methods: We conducted a 1:1 case-control study in a prospective cohort of pregnant women in Tianjin, China. Read More

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Long-term results of the Japanese multicenter Viabahn trial of heparin bonded endovascular stent grafts for long and complex lesions in the superficial femoral artery.

J Vasc Surg 2021 Jun 25. Epub 2021 Jun 25.

Kawasaki Medical School, Okayama, Japan.

Objective: To assess the long-term safety and efficacy of endovascular stent grafting to treat long, complex lesions in the superficial femoral artery (SFA).

Methods: This prospective, multicenter study at 15 Japanese hospitals assessed heparin bonded stent grafts for treating long SFA lesions in patients with symptomatic peripheral arterial disease. Inclusion criteria were Rutherford category 2-5 symptoms (grade 5 without active infection), ankle-brachial index (ABI) ≤ 0. Read More

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Calcification patterns in femoral and carotid atheromatous plaques: A comparative morphometric study.

Exp Ther Med 2021 Aug 11;22(2):865. Epub 2021 Jun 11.

Department of Vascular Surgery, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology, 540142 Târgu Mureș, Romania.

This comparative study was designed to focus on the mineral patterns in human atherosclerotic plaques based on quantitative measurements of calcium deposits through the morphometric method. A total of 101 atherosclerotic plaques were harvested by conventional transluminal angioplasty from the carotid artery (CA) and different segments of the femoral-popliteal axis (FPA), fixed in formalin and sent for histological processing. The histological grade of the atherosclerotic plaque and the calcification pattern were evaluated, followed by a morphometric analysis of the mineral deposits. Read More

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