113,988 results match your criteria sexual function


J Minim Invasive Gynecol 2021 May 10. Epub 2021 May 10.

Gynaecology Department. Institute Clinic of Gynaecology, Obstetrics and Neonatology, Hospital Clinic. Faculty of Medicine, University of Barcelona, Institut d`Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain.

Study Objective: We performed a long-term follow-up to quantify the impairment of sexual quality of life (SQL) and health-related quality of life (HRQL) in sexually active women following laparoscopic excision of deep infiltrating endometriosis (DIE).

Design: Prospective case-control study.

Setting: Hospital Clinic of Barcelona. Read More

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Genomic and Hormonal Biomarkers of Phthalate-Induced Male Rat Reproductive Developmental Toxicity Part II: A Targeted RT-qPCR Array Approach that Defines a Unique Adverse Outcome Pathway.

Toxicol Sci 2021 May 12. Epub 2021 May 12.

Fuquay Varina.

Previously, we demonstrated that exposure to some diortho-phthalate esters during sexual differentiation disrupts male reproductive development by reducing fetal rat testis testosterone production (T Prod) and gene expression in a dose-related manner. The objectives of the current project were to expand the number of test compounds that might reduce fetal T Prod, including phthalates, phthalate alternatives, pesticides, and drugs, and to compare reductions in T Prod with altered testis mRNA expression. We found that PEs that disrupt T Prod also reduced expression of a unique "cluster" of mRNAs for about 35 genes related to sterol transport, testosterone and insl3 hormone syntheses, and lipoprotein signaling and cholesterol synthesis. Read More

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Male and Female Sexual Function and Dysfunction; Andrology.

Allen D Seftel

J Urol 2021 May 13:101097JU0000000000001863. Epub 2021 May 13.

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Sex differences in biological aging with a focus on human studies.

Elife 2021 May 13;10. Epub 2021 May 13.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Aging is a complex biological process characterized by hallmark features accumulating over the life course, shaping the individual's aging trajectory and subsequent disease risks. There is substantial individual variability in the aging process between men and women. In general, women live longer than men, consistent with lower biological ages as assessed by molecular biomarkers, but there is a paradox. Read More

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[Literature research and traditional Chinese medicine properties of Aspalathus linearis].

Zhongguo Zhong Yao Za Zhi 2021 Apr;46(8):1960-1966

School of Chinese Medicine, Beijing University of Chinese Medicine Beijing 100029, China.

Aspalathus linearis is a needle-shaped shrub that grows in the Cedarberg mountains in southern South Africa, with an extremely high medicinal value. In 2014, China has approved A. linearis as a new food material. Read More

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Male sterility significantly elevates shape variation and fluctuating asymmetry of zygomorphic corolla in gynodioecious (Lamiaceae).

AoB Plants 2021 Jun 8;13(3):plab013. Epub 2021 Apr 8.

Department of Botany, Faculty of Science, Charles University, Prague 12843, Czech Republic.

Female flowers of gynodioecious plants usually have smaller corollas than bisexual flowers. This difference is explained as a developmental consequence of stamen abortion and as a result of stronger selection for larger corolla size in hermaphroditic flowers that solely ensure male function within populations. This study evaluated whether the size difference of zygomorphic corollas in a widely distributed gynodioecious herb is accompanied by variation in shape and bilateral fluctuating asymmetry of sexually differentiated flowers. Read More

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Comparison of bipolar plasmakinetic resection of prostate versus photoselective vaporization of prostate by a three year retrospective observational study.

Sci Rep 2021 May 12;11(1):10142. Epub 2021 May 12.

Department of Urology, The Second Xiangya Hospital of Central South University, Renmin Middle Road 139, Changsha, 410011, China.

Comprehensive evaluation of photoselective vaporization of the prostate (PVP) versus plasmakinetic resection of the prostate (PKRP) in treating benign prostatic hyperplasia (BPH) is inadequate. This single-centre, retrospective observational study was designed to compare their efficacy, complications and sexual function. A total of 215 patients under PVP or PKRP were included in the study, propensity score matching (PSM) was performed to match the baseline characteristics of the two groups, and perioperative and three-year follow-up data were compared between them. Read More

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A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2 neutralizing activity.

J Virol 2021 May 12. Epub 2021 May 12.

Stanford ChEM-H, Stanford University, Stanford, California, USA

HIV-1 infection is initiated by the viral glycoprotein Env, which, after interaction with cellular coreceptors, adopts a transient conformation known as the pre-hairpin intermediate (PHI). The N-heptad repeat (NHR) is a highly conserved region of gp41 exposed in the PHI; it is the target of the FDA-approved drug enfuvirtide and of neutralizing monoclonal antibodies (mAbs). However, to date these mAbs have only been weakly effective against tier-1 HIV-1 strains, which are most sensitive to neutralizing antibodies. Read More

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Size-dependent sex allocation in Solanum lycocarpum St. Hil. (Solanaceae).

Braz J Biol 2021 10;82:e237575. Epub 2021 May 10.

Universidade Federal de Lavras - UFLA, Departamento de Biologia, Programa de Pós-graduação em Botânica Aplicada, Lavras, MG, Brasil.

Resource allocation to reproduction can change depending on size, as predicted by the size-dependent sex allocation. This theory is based on the fact that small individuals will invest in the allocation of sex with lower cost of production, usually male gender. In plants, there are some andromonoecy species, presence of hermaphrodite and male flowers in the same individual. Read More

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A Prospective Study of Predictors and Consequences of Hooking Up for Sexual Minority Women.

Arch Sex Behav 2021 May 11. Epub 2021 May 11.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.

Hooking up, which refers to a sexual encounter (ranging from kissing to penetrative sex) between individuals who are not in a committed relationship, is an increasingly normative form of sexual exploration among emerging adults. Past research has focused on hookups within a heteronormative context, and some of this work has examined hookups as a way to cope with distress. Building on this work, we examined the role of hookups as a means for lesbian and bisexual women to cope with minority stress through increasing connection and engagement with the LGBTQ (lesbian/gay/bisexual/transgender/queer or questioning) community. Read More

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The impact of post-urethroplasty erectile dysfunction on the quality of life and treatment satisfaction.

Cent European J Urol 2021 15;74(1):116-120. Epub 2021 Jan 15.

Medical University of Gdańsk, Department of Urology, Gdańsk, Poland.

Introduction: The aim of this article was to assess the influence of sexual disorders after urethroplasty on patient's quality of life (QoL) and satisfaction of treatment.

Material And Methods: We studied 106 sexually active patients who underwent urethroplasty due to urethral stricture. Patients completed the Urethral Stricture Surgery - Patient Reported Outcome Measure (USS - PROM) and International Index of Erectile Function (IIEF-5) questionnaires before and after the treatment. Read More

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January 2021

Evaluation of the sensitivity of different doses of vasoactive drugs in diagnosing erectile dysfunction in impotent patients: a prospective case-control study.

Cent European J Urol 2021 6;74(1):109-115. Epub 2021 Feb 6.

Department of Andrology, Sexual Medicine and STIs, Faculty of Medicine, Cairo University, Egypt.

Introduction: Erectile dysfunction (ED) is one of the most common sexual disorders worldwide affecting about 30 million men in the United States, and an estimated 100 million men worldwide. Penile duplex doppler ultrasound (PDDU) is performed using an intracavernosal injection (ICI) of a vasoactive agent to demonstrate both arterial insufficiency and veno-occlusive dysfunction. This article aims to evaluate the sensitivity of different doses of different vasoactive agents used to diagnose ED in impotent patients. Read More

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February 2021

No evidence of sexual dimorphism in the tails of the swallowtail butterflies and .

Ecol Evol 2021 May 17;11(9):4744-4749. Epub 2021 Mar 17.

School of Biological Sciences, Faculty of Biology, Medicine and Health University of Manchester Manchester UK.

The European swallowtail butterfly () is so named, because of the long and narrow prominences extending from the trailing edge of their hindwings and, although not a true tail, they are referred to as such. Despite being a defining feature, an unequivocal function for the tails is yet to be determined, with predator avoidance (diverting an attack from the rest of the body), and enhancement of aerodynamic performance suggested. The swallowtail, however, is sexually size dimorphic with females larger than males, but whether the tail is also sexually dimorphic is unknown. Read More

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Effects of patients' understanding and choice of surgical types on postoperative outcomes of Peyronie's disease: a single-center retrospective study of 108 patients.

Asian J Androl 2021 May 11. Epub 2021 May 11.

Department of Urology and Andrology, Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, China.

Surgical correction can be considered for treating patients with a chronic phase of Peyronie's disease (PD) and persistent penile curvature. In clinical practice, some patients pay too much attention to surgical complications and refuse the recommended feasible surgical types. Meanwhile, they require operations according to their preferences. Read More

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Sexual Dimorphism in the Functional Development of the Cochlear Amplifier in Humans.

Ear Hear 2021 Jan 11. Epub 2021 Jan 11.

1Department of Communication Sciences & Disorders, The University of Texas Rio Grande Valley, Edinburg, Texas, USA 2Department of Communication Disorders, NM State University, Las Cruces, New Mexico, USA 3Department of Speech, Language, and Hearing Sciences, University of Arizona, Tucson, USA and 4School of Mathematical and Statistical Sciences, The University of Texas Rio Grande Valley, Edinburg, Texas, USA.

Objectives: Otoacoustic emissions, a byproduct of active cochlear mechanisms, exhibit a higher magnitude in females than in males. The relatively higher levels of androgen exposure in the male fetus are thought to cause this difference. Postnatally, the onset of puberty is also associated with the androgen surge in males. Read More

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January 2021

Taraidiwa ["We Have Been Raided"]: Effects of and Meanings Ascribed to an Assault on an LGBTI Function in Harare, Zimbabwe.

J Homosex 2021 May 11:1-21. Epub 2021 May 11.

Institute of Health and Society, University of Oslo, Oslo, Norway.

Drawing on first-hand fieldwork experiences, conversations and interviews, this paper describes and analyses the violent attack on a GALZ event in Zimbabwe in 2014. A gang of unidentifiable men stormed the event and assaulted those present. The paper explores this attack on the LGBTI community in Zimbabwe as a sign, drawing on Peirce's theorizing of signs as triadic. Read More

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Health-related quality of life in bladder cancer patients: bladder cancer-specific instruments and domains. Part 2.

Curr Opin Urol 2021 May 10. Epub 2021 May 10.

Department of Urology, Federal Armed Services Hospital Koblenz, Koblenz, Germany Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria Department of Urology, The Jikei University School of Medicine, Tokyo, Japan Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Department of Urology, Uro-Oncology, Robot-Assisted and Specialized Urologic Surgery, University Hospital Cologne, Cologne, Germany Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic Department of Urology, Weill Cornell Medical College, New York, New York, USA Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria Department of Urology, University of Jordan, Amman, Jordan.

Purpose Of Review: Several instruments have been designed to evaluate health-related quality of life (HRQoL) in patients with bladder cancer (BC). However, they vary in purpose, domains, and quality. To identify QoL instruments that have been validated for BC patients and to critically assess their domains and limitations. Read More

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Structural variations in papaya genomes.

BMC Genomics 2021 May 10;22(1):335. Epub 2021 May 10.

Department of Plant Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

Background: Structural variations (SVs) are a type of mutations that have not been widely detected in plant genomes and studies in animals have shown their role in the process of domestication. An in-depth study of SVs will help us to further understand the impact of SVs on the phenotype and environmental adaptability during papaya domestication and provide genomic resources for the development of molecular markers.

Results: We detected a total of 8083 SVs, including 5260 deletions, 552 tandem duplications and 2271 insertions with deletion being the predominant, indicating the universality of deletion in the evolution of papaya genome. Read More

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Is it Worth Starting Sexual Rehabilitation Before Radical Prostatectomy? Results From a Systematic Review of the Literature.

Front Surg 2021 21;8:648345. Epub 2021 Apr 21.

Department of Medicine, Surgery, Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.

Sexual dysfunction (SD) is a frequent side effect associated with radical prostatectomy (RP) for prostate cancer (PCa). Some studies have showed the benefit associated with preoperative sexual rehabilitation (prehabilitation) and Enhanced Recovery After Surgery (ERAS) for RP, but no clear clinical recommendations are available yet. Our aim was to conduct a systematic review on sexual prehabilitation prior to RP for patients with a localized PCa and analyze the impact on postoperative sexual health compared with the standard post-operative care. Read More

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Efficacy and risk of sexual orientation change efforts: a retrospective analysis of 125 exposed men.

F1000Res 2021 18;10:222. Epub 2021 Mar 18.

Southern California Seminary, El Cajon, CA, 92019, USA.

Background:  Voluntary therapeutic interventions to reduce unwanted same-sex sexuality are collectively known as sexual orientation change efforts (SOCE).  To date almost all evidence addressing the contested question whether SOCE is effective or safe has consisted of anecdotes or very small sample qualitative studies of persons who currently identify as sexual minority and thus by definition failed to change.  We conducted this study to examine the efficacy and risk outcomes for a group of SOCE participants unbiased by current sexual orientation. Read More

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Brief Report: Sexual Wellbeing in Heterosexual, Mostly Heterosexual, and Bisexually Attracted Men and Women.

Tierney K Lorenz

Int J Sex Health 2019 5;31(3):339-349. Epub 2019 Jul 5.

Department of Psychology and Center for Brain, Biology and Behavior, University of Nebraska-Lincoln, Lincoln, Nebraksa, USA.

Objective: To assess differences in sexual wellbeing among men and women with exclusively heterosexual, mostly heterosexual, and bisexual attractions.

Method: An anonymous online survey in a convenience sample of 597 young adults (394 women, 203 men; average age = 20.04) assessed patterns of sexual attraction, desire, sexual functioning, and sexual satisfaction using validated questionnaires. Read More

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Function of Small Peptides During Male-Female Crosstalk in Plants.

Front Plant Sci 2021 23;12:671196. Epub 2021 Apr 23.

College of Life Sciences, National Key Laboratory of Wheat and Maize Crop Science, Henan Agricultural University, Zhengzhou, China.

Plant peptides secreted as signal molecular to trigger cell-to-cell signaling are indispensable for plant growth and development. Successful sexual reproduction in plants requires extensive communication between male and female gametophytes, their gametes, and with the surrounding sporophytic tissues. In the past decade, it has been well-documented that small peptides participate in many important reproductive processes such as self-incompatibility, pollen tube growth, pollen tube guidance, and gamete interaction. Read More

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The East Asian Erotic Picture Dataset and Gender Differences in Response to Opposite-Sex Erotic Stimuli in Chinese College Students.

Front Psychol 2021 21;12:648271. Epub 2021 Apr 21.

Reward, Competition and Social Neuroscience Lab, Department of Psychology, School of Social and Behavioral Sciences, Nanjing University, Nanjing, China.

Understanding the processing of sexual stimuli has become a significant part of research on human sexuality. In addition to individual characteristics (gender and sexual orientation), empirical studies have shown that cultural factors play an important role in sexual stimuli processing. The attitudes toward sex have been reported to be more conservative in East Asian societies as compared to western countries, and significantly more sexual difficulties are observed among East Asian people. Read More

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Treatments of Sexual Dysfunction in Opioid Substitution Therapy Patients: A Systematic Review and Meta-Analysis.

Int J Med Sci 2021 12;18(11):2372-2380. Epub 2021 Apr 12.

Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000 Cheras, Kuala Lumpur, Malaysia.

Sexual dysfunction is a common condition in the opioid substitution therapy (OST) population. We aimed to determine the efficacy and safety of treatment for sexual dysfunction in the OST population. We searched for interventional studies from Medline, PubMed, and Scopus. Read More

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Incidence and risk factors of sexual dysfunction in young breast cancer survivors.

Ann Palliat Med 2021 Apr;10(4):4428-4434

Department of General Surgery, the First Medical Center, Chinese PLA General Hospital, Beijing, China.

Background: Sexual dysfunction is common in postoperative breast cancer patients, which seriously affects the quality of life of the patients, especially young patients. The aim of the present study was to investigate the incidence and risk factors of sexual dysfunction in young breast cancer survivors, so as to provide evidence for further intervention.

Methods: A total of 201 young breast cancer patients who were hospitalized in our department from October 2017 to October 2018 were retrospectively enrolled. Read More

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Digital Frozen Sections with Fluorescence Confocal Microscopy During Robot-assisted Radical Prostatectomy: Surgical Technique.

Eur Urol 2021 May 5. Epub 2021 May 5.

Department of Urology, Ospedale Policlinico e Nuovo Ospedale Civile S. Agostino Estense Modena, University of Modena and Reggio Emilia, Modena, Italy.

Background: Robot-assisted radical prostatectomy (RARP) involves a tradeoff between oncological control and functional outcomes. Intraoperative control of surgical margins (SMs) may help in ensuring the safety of the dissection. Fluorescence confocal microscopy (FCM) is an effective method for interpretation of prostate tissue and provides digital images with an appearance similar to hematoxylin-eosin staining. Read More

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Correlates of memory and executive function in mid-aged and older adults in the CLSA: A minority stress approach.

J Gerontol B Psychol Sci Soc Sci 2021 May 8. Epub 2021 May 8.

School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.

Objectives: Maintaining cognitive function is an important component of healthy aging. There is increasing recognition that extraneous factors expedite the typical cognitive aging process. Risk factors for cognitive decline cluster around inequalities and disproportionally affect minority and vulnerable groups. Read More

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Premature Ejaculation, True or False? Clinical evaluation of PE patients with multiple intercourse in one day.

Andrologia 2021 May 8:e14097. Epub 2021 May 8.

Department of Urology, Chinese Academy of Medical Science, Peking Union Medical College, Peking Union Medical College Hospital, Beijing, China.

Clinical characteristics of 216 adult males previously diagnosed with premature ejaculation (PE) were studied. Using a survey questionnaire, characteristics included intravaginal ejaculation latency time (IELT), penile hardness scores and the refractory period (RP). Ninety-four PE patients reported they had experienced vaginal intercourse more than once (2 to 4 times) in one day (~44%). Read More

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Reproductive- and social-state plasticity of multiple sensory systems in a cichlid fish.

Integr Comp Biol 2021 May 7. Epub 2021 May 7.

Department of Biological Sciences, 202 Life Sciences Bldg., Louisiana State University, Baton Rouge, LA. 70803.

Intra- and inter-sexual communication is vital to the survival and reproductive success of animals. In species that cycle in and out of breeding or other physiological condition, sensory function can be modulated to optimize communication at crucial times. Little is known, however, about how widespread this sensory plasticity is across taxa, whether it occurs in multiple senses or both sexes within a species, and what potential modulatory substances and substrates are involved. Read More

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Evidence for a syncytial origin of eukaryotes from ancestral state reconstruction.

Genome Biol Evol 2021 May 7. Epub 2021 May 7.

Institute for Molecular Evolution, Heinrich - Heine University Düsseldorf, 40225 Düsseldorf, Germany.

Modern accounts of eukaryogenesis entail an endosymbiotic encounter between an archaeal host and a proteobacterial endosymbiont, with subsequent evolution giving rise to a unicell possessing a single nucleus and mitochondria. The mononucleate state of the last eukaryotic common ancestor, LECA, is seldom, if ever, questioned, even though cells harboring multiple (syncytia, coenocytes, polykaryons) are surprisingly common across eukaryotic supergroups. Here we present a survey of multinucleated forms. Read More

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