84,690 results match your criteria sexual determination


Psychometric evaluation of the Muscle Dysmorphic Disorder Inventory (MDDI) among cisgender gay men and cisgender lesbian women.

Body Image 2021 May 4;38:241-250. Epub 2021 May 4.

Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

Despite increasing empirical interest in muscle dysmorphia (MD), a dearth of research has assessed this construct in sexual minority populations. In particular, the psychometric properties of one of the most widely used measures of MD symptoms-the Muscle Dysmorphic Disorder Inventory (MDDI)-have not been evaluated in sexual minority populations despite emerging evidence suggesting differential risk for MD symptoms across sexual orientation groups. In this study, we assessed the psychometric properties of the MDDI in a sample of 715 cisgender gay men and 404 cisgender lesbian women ages 18-50 years who participated in a large-scale national longitudinal cohort study of sexual and gender minority adults. Read More

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Scaling Up and Out HIV Prevention and Behavioral Health Services to Latino Sexual Minority Men in South Florida: Multi-Level Implementation Barriers, Facilitators, and Strategies.

AIDS Patient Care STDS 2021 May;35(5):167-179

Department of Psychology, University of Miami, Miami, Florida, USA.

Latino sexual minority men (LSMM) are disproportionately affected by HIV in the United States. Concurrently, behavioral health disparities, including mental health and substance use concerns, worsen HIV disparities affecting LSMM. Yet, evidence-based HIV prevention and behavioral health services are insufficiently scaled up and out to this population, perpetuating health disparities, thwarting efforts to control the HIV epidemic, and highlighting the need for culturally relevant evidence-based implementation strategies that address these disparities. Read More

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Organ geometry channels reproductive cell fate in the Arabidopsis ovule primordium.

Elife 2021 May 7;10. Epub 2021 May 7.

Plant and Microbial Biology, University of Zürich, Zürich, Switzerland.

In multicellular organisms, sexual reproduction requires the separation of the germline from the soma. In flowering plants, the female germline precursor differentiates as a single spore mother cell (SMC) as the ovule primordium forms. Here, we explored how organ growth contributes to SMC differentiation. Read More

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18-Year-old patient with Klinefelter syndrome (47, XXY) and complete androgen insensitivity syndrome (CAIS) - case report.

Gynecol Endocrinol 2021 May 7:1-4. Epub 2021 May 7.

Department of Gynecological Endocrinology, Poznan University of Medical Sciences, Poznan, Poland.

Aims: The aims of the presented case report are to emphasize the importance of a proper diagnostics and treatment in the case of the coexistence of Klinefelter syndrome (KS, 47 XXY) and complete androgen insensitivity syndrome (CAIS). Since there is no causal treatment it is necessary to provide the patient with a good quality of life, including psychological and sexological support.

Materials And Methods: The presented case report is the retrospective analysis of the patient's medical history over the 3 years. Read More

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[Current approach to diagnosis of chronic prostatitis].

Urologiia 2021 May(2):32-39

TB Research Institute of Ministry of Health of Russia, Novosibirsk, Russia.

Introduction: The problem of chronic prostatitis is still to be resolved.

Aim: to compare the frequency of the main symptoms (pain, dysuria, sexual dysfunction) in patients with chronic bacterial and abacterial prostatitis, as well as prostate tuberculosis (PTB); to determine the prevalence of latent infectious prostatitis in patients with chronic abacterial prostatitis (CAP).

Materials And Methods: A total 73 men who were followed with a diagnosis of chronic prostatitis for at least two years and had a history of at least three exacerbations per year were included in the study. Read More

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Saffron improves life and sleep quality, glycemic status, lipid profile and liver function in diabetic patients: A double-blind, placebo-controlled, randomized clinical trial.

Int J Clin Pract 2021 May 7:e14334. Epub 2021 May 7.

Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Type 2 diabetes (T2D) is a metabolic disorder that is related to hyperglycemia, hyperlipidemia, and liver dysfunction and has detrimental effects on a patient's mental health. Hence, the current study investigated the effects of saffron supplementation on dietary intake, anthropometric measures, mood, sleep quality, and metabolic biomarkers in overweight/obese patients with T2D.

Methods: In a double-blind, randomized controlled trial, 70 overweight/obese patients with T2D were randomly allocated to two groups and received 100 mg/day saffron or placebo for eight weeks. Read More

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Profiles of Maltreatment in the Child Welfare System: Predicting Mental Health Outcomes and Examining Age as a Moderator.

J Trauma Stress 2021 May 6. Epub 2021 May 6.

Department of Psychology, Loyola University Chicago, Chicago, Illinois, USA.

This longitudinal study explored the unique profiles of maltreatment among youth in the child welfare system and examined their relation to mental health outcomes over time. We additionally examined the moderating role of age. Participants included 316 youth in the foster care system (age range: 6-13 years). Read More

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Donor Commitments and Disbursements for Sexual and Reproductive Health Aid in Kenya, Tanzania, Uganda and Zambia.

Front Public Health 2021 20;9:645499. Epub 2021 Apr 20.

Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht Centre for Pharmaceutical Policy and Regulation, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands.

Sexual and Reproductive Health and Rights (SRHR) investments are critical to people's well-being. However, despite the demonstrated returns on investments, underfunding of SRHR still persists. The objective of this study was to characterize donor commitments and disbursements to SRH aid in four sub-Saharan countries of Kenya, Tanzania, Uganda and Zambia and to compare trends in donor aids with SRH outcome and impact indicators for each of these countries. Read More

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Are There Familial Patterns of Symptom Dimensions in Obsessive-Compulsive Disorder?

Front Psychiatry 2021 20;12:651196. Epub 2021 Apr 20.

Accelerator Program for Discovery in Brain Disorders Using Stem Cells, National Institute of Mental Health & Neuro Sciences (NIMHANS), Bangalore, India.

Obsessive-compulsive disorder (OCD) is a heterogeneous illness, and emerging evidence suggests that different symptom dimensions may have distinct underlying neurobiological mechanisms. We aimed to look for familial patterns in the occurrence of these symptom dimensions in a sample of families with at least two individuals affected with OCD. Data from 153 families (total number of individuals diagnosed with DSM-5 OCD = 330) recruited as part of the Accelerator Program for Discovery in Brain Disorders using Stem Cells (ADBS) was used for the current analysis. Read More

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Sex differences in Behavioral and Psychological Signs and Symptoms of Dementia Presentation Regarding Nursing Home Residents with Cognitive Impairment Suffering from Pain- Results of the Services and Health for Elderly in Long-Term Care Study.

J Am Med Dir Assoc 2021 May 3. Epub 2021 May 3.

Competence Center of Geriatric Medicine, Helios Medical Center Bonn/Rhein-Sieg, Academic Teaching Hospital, University Bonn, Germany; Department of Orthopedics and Trauma Surgery, University Hospital Bonn, Germany. Electronic address:

Objective: Behavioral and psychological symptoms of dementia (BPSD) place a heavy burden on patients as well as caregivers. Recently, pain was identified as an important determinant of BPSD. However, it is not yet known what influence sex has on BPSD and pain. Read More

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Dismantling, optimising, and personalising internet cognitive behavioural therapy for depression: a systematic review and component network meta-analysis using individual participant data.

Lancet Psychiatry 2021 May 3. Epub 2021 May 3.

Department of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.

Background: Internet cognitive behavioural therapy (iCBT) is a viable delivery format of CBT for depression. However, iCBT programmes include training in a wide array of cognitive and behavioural skills via different delivery methods, and it remains unclear which of these components are more efficacious and for whom.

Methods: We did a systematic review and individual participant data component network meta-analysis (cNMA) of iCBT trials for depression. Read More

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Sexually transmitted infections and factors associated with risky sexual practices among female sex workers: A cross sectional study in a large Andean city.

PLoS One 2021 6;16(5):e0250117. Epub 2021 May 6.

School of Medicine, Universidad Internacional de Ecuador, Quito, Ecuador.

Background: There are limited published data on factors related to risky sexual practices (RSP) affecting sexually transmitted infections (STIs) among female sex workers (FSWs) in Ecuador.

Methods: Cross-sectional study of FSWs presenting for a consultation in a primary health care centre during 2017. A questionnaire was administered to collect information on RSP and potential risk factors including age, membership of an FSW association, self-report of previous STI diagnosis, previous treatment for suspected STI and temporary migration for sex work. Read More

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Challenges experienced by patients with hypertension in Ghana: A qualitative inquiry.

PLoS One 2021 6;16(5):e0250355. Epub 2021 May 6.

Professor Emeritus of Applied Psychology, Department of Works and Social Psychology Maastricht University, Maastricht, the Netherland.

Background: Hypertension (HPT) is an essential public health problem affecting both lower and middle-income countries disproportionately. Evidence suggests that HPT is the leading risk factor for cardiovascular diseases and chronic kidney disease. Yet, challenges faced by patients with HPT in Ghana are not sufficiently explored. Read More

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Structural, Functional, and Metabolic Brain Differences as a Function of Gender Identity or Sexual Orientation: A Systematic Review of the Human Neuroimaging Literature.

Arch Sex Behav 2021 May 6. Epub 2021 May 6.

Division of Health Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.

This review systematically explored structural, functional, and metabolic features of the cisgender brain compared with the transgender brain before hormonal treatment and the heterosexual brain compared to the homosexual brain from the analysis of the neuroimaging literature up to 2018, and identified and discussed subsequent studies published up to March 2021. Our main aim was to help identifying neuroradiological brain features that have been related to human sexuality to contribute to the understanding of the biological elements involved in gender identity and sexual orientation. We analyzed 39 studies on gender identity and 24 on sexual orientation. Read More

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Influence of Stress, Gender, and Minority Status on Cardiovascular Disease Risk in the Hispanic/Latino Community: Protocol for a Longitudinal Observational Cohort Study.

JMIR Res Protoc 2021 May 6;10(5):e28997. Epub 2021 May 6.

Department of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States.

Background: Hispanic/Latino sexual and gender minorities (SGM) are the fastest growing ethnic group of SGM in the United States. Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among Hispanics/Latinos. SGM inequities in CVD risk have been identified as early as young adulthood, and minority stress has been identified as a potential mediator. Read More

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Exploring Perceived Barriers and Facilitators of PrEP Uptake among Young People in Uganda, Zimbabwe, and South Africa.

Arch Sex Behav 2021 May 5. Epub 2021 May 5.

Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine Uganda Research Unit, P.O. Box 49, Entebbe, Uganda.

Pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy. Few studies have explored adolescents and young people's perspectives toward PrEP. We conducted 24 group discussions and 60 in-depth interviews with males and females aged 13-24 years in Uganda, Zimbabwe, and South Africa between September 2018 and February 2019. Read More

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Minimal Effects of Proto-Y Chromosomes on House Fly Gene Expression in Spite of Evidence that Selection Maintains Stable Polygenic Sex Determination.

Genetics 2019 Sep;213(1):313-327

Department of Biology and Biochemistry, University of Houston, Texas 77204-5001.

Sex determination pathways evolve fast and can even be variable within species. Son et al. used the house fly as a model to study the evolution of sex determination because it has a male. Read More

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September 2019

Minimal Effects of Proto-Y Chromosomes on House Fly Gene Expression in Spite of Evidence that Selection Maintains Stable Polygenic Sex Determination.

Genetics 2019 Sep;213(1):313-327

Department of Biology and Biochemistry, University of Houston, Texas 77204-5001.

Sex determination pathways evolve fast and can even be variable within species. Son et al. used the house fly as a model to study the evolution of sex determination because it has a male. Read More

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September 2019

Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans.

Genetics 2020 Mar;214(3):635-649

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710.

This study demonstrated that the ribosomal proteins Rpl22 and Rpl39 encoded by the MAT locus of Cryptococcus neoformans are essential. Focusing on the RPL22a and RPL22α alleles, Ianiri et al. found differential expression of the two RPL22. Read More

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Comparative Genomics and Transcriptomics To Analyze Fruiting Body Development in Filamentous Ascomycetes.

Genetics 2019 Dec;213(4):1545-1563

Department of Molecular and Cellular Botany, Ruhr-Universität Bochum, 44780 Bochum, Germany.

Many filamentous ascomycetes develop three-dimensional fruiting bodies for production and dispersal of sexual spores. Fruiting bodies are among the most complex structures differentiated by ascomycetes; however, the molecular mechanisms underlying this process are insufficiently understood. Previous comparative transcriptomics analyses of fruiting body development in different ascomycetes suggested that there might be a core set of genes that are transcriptionally regulated in a similar manner across species. Read More

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December 2019

The Role of Anti-Müllerian Hormone in Testis Differentiation Reveals the Significance of the TGF-β Pathway in Reptilian Sex Determination.

Genetics 2019 Dec;213(4):1317-1327

College of Biological and Environmental Sciences, Zhejiang Wanli University, Ningbo 315100, China.

Anti-Müllerian hormone (Amh, or Müllerian-inhibiting substance, Mis), a member of TGF-β superfamily, has been well documented in some vertebrates as initiator or key regulator in sexual development, and particularly in fish. However, its functional role has not yet been identified in reptiles. Here, we characterized the Amh gene in the Chinese soft-shelled turtle Pelodiscus sinensis, a typical reptilian species exhibiting ZZ/ZW sex chromosomes. Read More

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December 2019

The Role of Anti-Müllerian Hormone in Testis Differentiation Reveals the Significance of the TGF-β Pathway in Reptilian Sex Determination.

Genetics 2019 Dec;213(4):1317-1327

College of Biological and Environmental Sciences, Zhejiang Wanli University, Ningbo 315100, China.

Anti-Müllerian hormone (Amh, or Müllerian-inhibiting substance, Mis), a member of TGF-β superfamily, has been well documented in some vertebrates as initiator or key regulator in sexual development, and particularly in fish. However, its functional role has not yet been identified in reptiles. Here, we characterized the Amh gene in the Chinese soft-shelled turtle Pelodiscus sinensis, a typical reptilian species exhibiting ZZ/ZW sex chromosomes. Read More

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December 2019

Comparative Genomics and Transcriptomics To Analyze Fruiting Body Development in Filamentous Ascomycetes.

Genetics 2019 Dec;213(4):1545-1563

Department of Molecular and Cellular Botany, Ruhr-Universität Bochum, 44780 Bochum, Germany.

Many filamentous ascomycetes develop three-dimensional fruiting bodies for production and dispersal of sexual spores. Fruiting bodies are among the most complex structures differentiated by ascomycetes; however, the molecular mechanisms underlying this process are insufficiently understood. Previous comparative transcriptomics analyses of fruiting body development in different ascomycetes suggested that there might be a core set of genes that are transcriptionally regulated in a similar manner across species. Read More

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December 2019

Comparing the Effectiveness of Sexual Counseling Based on PLISSITand BETTER Models on Sexual Selfdisclosure in Women with Sexual Problems after Childbirth: A Randomized Trial.

Iran J Nurs Midwifery Res 2021 Jan-Feb;26(1):68-74. Epub 2021 Jan 18.

Social Determinants of Health Research Center, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Sexual self-disclosure is one of the factors that affect sexual satisfaction. The aim of this study was to assess the efficacy of individual therapy using the Bring up, Explain, Tell, Timing, Educate, and Record (BETTER model) in comparison to individual therapy using the Permission, Limited Information, Specific Suggestions, and Intensive Therapy (PLISSIT model) in terms of increasing sexual self-disclosure in women with sexual problems after childbirth.

Materials And Methods: This randomized trial was conducted in 2017 in Mashhad, Iran. Read More

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January 2021

Sexual dimorphism in mud crabs: a tale of three sympatric species.

PeerJ 2021 12;9:e10936. Epub 2021 Apr 12.

Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia.

Sexual dimorphism is a common phenomenon in the animal kingdom. To test the consistency of sexual dimorphism patterns among sympatric species of the same genus, ten morphometric characteristics of mud crabs , and were measured and compared using Discriminant Function Analysis (DFA). The descriptive analysis revealed that in all three species, body size dimensions and cheliped dimensions were significantly larger in males whereas the abdomen width was female-biased. Read More

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Cross-sectional analysis of the Parkinson's disease Non-motor International Longitudinal Study baseline non-motor characteristics, geographical distribution and impact on quality of life.

Sci Rep 2021 May 5;11(1):9611. Epub 2021 May 5.

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Growing evidence suggests that non-motor symptoms (NMS) in Parkinson's disease (PD) have differential progression patterns that have a different natural history from motor progression and may be geographically influenced. We conducted a cross-sectional analysis of 1607 PD patients of whom 1327 were from Europe, 208 from the Americas, and 72 from Asia. The primary objective was to assess baseline non-motor burden, defined by Non-Motor Symptoms Scale (NMSS) total scores. Read More

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Substance use treatment partially mitigates association between methamphetamine use and STI risk: findings from the NSDUH cohort.

Sex Transm Infect 2021 May 5. Epub 2021 May 5.

College of Nursing, The Ohio State University, Columbus, Ohio, USA

Background: In recent years, both methamphetamine use and STIs have been on the rise in the USA. In this analysis, we sought to ascertain whether the risk of STIs and HIV among methamphetamine users was moderated on the basis of participation in substance use treatment programmes.

Methods: Data came from the National Survey on Drug Use and Health, 2015-2019. Read More

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Sex, drugs and techno - a qualitative study on finding the balance between risk, safety and pleasure among men who have sex with men engaging in recreational and sexualised drug use.

BMC Public Health 2021 May 5;21(1):863. Epub 2021 May 5.

Department of Global Public Health, Karolinska Institutet, 171 77, Stockholm, Sweden.

Background: Recreational and sexual drug use among men who have sex with men may result in increased risk of poor health. The aim of this study was to better understand drug use and harm reduction techniques among Swedish men who have sex with men traveling to Berlin in order to improve the health of this population and inform public health strategies.

Methods: A qualitative study based on semi-structured interviews with 15 Swedish men aged 23-44 with experience of drug use were recruited through network sampling. Read More

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Determination of the factors affecting sexual violence against women in Turkey: a population-based analysis.

BMC Womens Health 2021 May 5;21(1):188. Epub 2021 May 5.

Department of Econometrics, Faculty of Economics and Administrative Sciences, Ataturk University, Erzurum, Turkey.

Background: Sexual violence is one of the most investigated types of violence by national and international decision makers. The purpose of this study was to detect the factors that affect sexual violence against women in Turkey.

Methods: In this study, a cross-sectional data set was employed from the survey titled the National Research on Domestic Violence against Women in Turkey, which was conducted by the Hacettepe University Institute of Population Studies. Read More

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