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J Sex Med 2022 Jul;19(7):1098-1115

Department of Obstetrics and Gynecology, University Hospitals Schleswig-Holstein, Kiel, Germany.

Background: Changes in sex hormones during menopause may have detrimental effects on a woman's sexual function and cause mood disorders. The treatment of both conditions is a challenge in gynecology.

Aim: To review the published literature on sexual function and mood disorders among peri- and postmenopausal women. Read More

J Affect Disord 2022 Jun 22. Epub 2022 Jun 22.

Baylor College of Medicine Children's Foundation Malawi, Tingathe Outreach Community Program, Lilongwe, Malawi; Baylor International Pediatric AIDS Initiative at Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.

Introduction: Adverse childhood experiences (ACEs) have been linked to common mental disorders (CMDs) such as anxiety and depressive thoughts. We examined the prevalence of ACEs and their association with CMDs among pregnant women living with HIV (PWLHIV) in Malawi-an HIV endemic resource-limited setting.

Methods: This is a cross-sectional study of 798 PWLHIV enrolled in the VITAL Start trial in Malawi (10/2018 to 06/2021) (NCT03654898). Read More

Gen Hosp Psychiatry 2022 Jun 16;78:9-13. Epub 2022 Jun 16.

Center for Psychotherapy Research, University Hospital Heidelberg, Heidelberg, Germany.

Objective: Although traumatic stress including childhood maltreatment (CM) has a profound impact on mental health, its relation to pathological skin picking (PSP) has been understudied and results remain inconclusive. Likewise, posttraumatic stress disorder (PTSD) as the most typical sequelae of traumatic stress has hardly been investigated in those with PSP. The objective of our online case-control study was to shed further light on this issue. Read More

Drug Alcohol Depend 2022 May 28;237:109511. Epub 2022 May 28.

Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI, USA; Center for Sexuality and Health Disparities, University of Michigan, Ann Arbor, MI, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA; Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.

Introduction: Criminal legal system (CLS) exposed adults experience higher rates of substance use, substance use disorder (SUD), and overdose. As most CLS exposed adults are not incarcerated, it is important to focus on CLS exposure across the carceral continuum.

Methods: This research used pooled data from adult respondents (N = 206,314) in the National Survey on Drug Use and Health (2015-2019). Read More

J Subst Abuse Treat 2022 Jun 16;140:108826. Epub 2022 Jun 16.

University of Washington Department of Psychology, Guthrie Hall, Seattle, WA 98195-1525, United States.

Introduction: High risk sex-such as sex with multiple partners, condomless sex, or transactional or commercial sex-is a risk factor in individuals with substance use disorders (SUDs). SUD treatment can reduce sexual risk behavior, but interventions to reduce such behavior in this context have not been consistently effective. This study sought to determine if the impact of treatment on sexual risk behavior can be increased. Read More

Discov Oncol 2022 Jun 25;13(1):52. Epub 2022 Jun 25.

Colorectal Unit, First Department of Propaedeutic Surgery, Medical School of National and Kapodistrian University of Athens, Hippocration Hospital, 114 Vas Sofias Ave, 11527, Athens, Greece.

Aim: The aim of this review was to collect all available literature data analysing the effects of the anastomotic leak (AL) on post-sphincter preserving rectal cancer surgery bowel and urogenital function as well as to quality of life (QoL) dimensions.

Methods: A literature search of the PubMed and Embase electronic databases was conducted by two independent investigators and all studies using either functional parameters or QoL as a primary or secondary endpoint after a rectal cancer surgery AL were included.

Results: Amongst the 13 identified studies focusing on the post-AL neorecto-anal function, 3 case-matched studies,3 comparative studies and 1 population-based study supported the deleterious effects of the AL on bowel function, with disturbances of the types of high bowel movement frequency, urgency and increased incontinent episodes to predominate. Read More

Int Urogynecol J 2022 Jun 25. Epub 2022 Jun 25.

Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Introduction And Hypothesis: Patients presenting with lower urinary tract symptoms (LUTS) may report a history of sexual abuse (SA), and survivors of SA may report LUTS; however, the nature of the relationship is poorly understood. The aim of this review is to systematically evaluate studies that explore LUT dysfunction in survivors of SA.

Methods: A systematic literature search of six databases, Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, CINAHL, AMED, and PsycINFO, was performed. Read More

Int Urogynecol J 2022 Jun 25. Epub 2022 Jun 25.

Division of Female Pelvic Medicine and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

Introduction And Hypothesis: Ehlers-Danlos Syndrome (EDS) is a group of inherited connective tissue disorders associated with abnormal collagen, and is more prevalent in women than in men. The aim of this cross-sectional study was to characterize pelvic floor symptoms in cisgender women with EDS and to describe their impact on quality of life.

Methods: An online questionnaire on obstetric and gynecological experiences of cisgender women with EDS was disseminated through EDS patient societies and social media. Read More

Mil Med 2022 Jun 25. Epub 2022 Jun 25.

Department of Medical & Clinical Psychology, Uniformed Services University, Bethesda, MD 20814, USA.

Introduction: Reports of sexual assault (SA) in the U.S. Military have increased in recent years. Read More

Am J Hum Biol 2022 Jun 25:e23776. Epub 2022 Jun 25.

Centre for Research and Education, County Council of Värmland, Karlstad, Sweden.

Objectives: Digit ratio (2D:4D) might reflect prenatal testosterone exposure and has been used as a putative marker for androgen related outcomes. However, such associations might be inflicted by confounders. Application of 2D:4D in epidemiological research motivate identification of biological background determinants. Read More

Congenit Anom (Kyoto) 2022 Jun 24. Epub 2022 Jun 24.

Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Aichi, Japan.

GATA4 is known to be a causative gene for congenital heart disease, but has also now been associated with disorders of sexual development (DSD). We here report a pathogenic variant of GATA4 in a 46,XY DSD patient with an atrial septal defect, identified by whole-exome sequencing to be c.487C>T (p. Read More

J Pak Med Assoc 2022 Jun;72(6):1193-1197

Department of Surgery, Section Urology, Aga Khan University Hospital, Karachi, Pakistan.

This study was conducted to determine the frequency of female sexual dysfunction in patients with urinary incontinence and lower urinary tract symptoms (UI/LUTS). Female patients between 18 and 60 years of age with lower urinary tract symptoms for more than three months were included and Female Sexual Function Index (FSFI) questionnaire was administered. Ninety-seven patients with mean age of 48±12. Read More

J Pak Med Assoc 2022 Jun;72(6):1025-1030

Department of Gynaecology and Obstetrics, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.

Objectives: To assess knowledge, attitude and practice of medical and paramedical staff about cervical cancer as well as its screening and prevention.

Methods: The descriptive cross-sectional study was conducted at the Jinnah Post-graduate Medical Centre, Karachi, from March 1 to August 30, 2019, and comprised women medical and paramedical staff randomly selected from different specialties. Data was collected using a structured questionnaire. Read More

Surg Radiol Anat 2022 Jun 24. Epub 2022 Jun 24.

Department of Anatomy, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Purpose: The purpose of the present study was to analyze the dimensions of the crista galli (CG) in preserved skulls, and to examine the role of the morphometry and morphology of the CG on the sex estimation.

Methods: Anteroposterior, superoinferior, and laterolateral diameters of the CG were measured of 207 preserved adult skulls of Anatolia origin with known sex (108 males, 99 females) in the Anatolian population. CG were morphologically classified into three types according to the dimensions. Read More

AIDS Behav 2022 Jun 25. Epub 2022 Jun 25.

Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop E-46, Atlanta, GA, USA.

Persons who inject drugs (PWID) and exchange sex face disproportionate HIV rates. We assessed prevalence of exchange sex (receiving money/drugs for sex from ≥ 1 male partner(s) during the past year) among cisgender PWID, separately for women and men with a history of sex with men (MSM). We examined factors associated with exchange sex, including sociodemographic characteristics, sexual and drug use behaviors, and healthcare access/utilization. Read More

Mol Psychiatry 2022 Jun 24. Epub 2022 Jun 24.

Department of Psychiatry, Gifu University Graduate School of Medicine, Gifu, Japan.

Reproductive behaviors are associated with risks for psychiatric disorders. Reproductive phenotypes are moderately heritable and have genetic overlaps with risks for psychiatric disorders. However, the genetic and causal relationships between anxiety-related disorders or specific anxiety disorders and reproductive phenotypes remain unknown. Read More

J Sex Med 2022 Jun 21. Epub 2022 Jun 21.

Université du Québec à Montréal, Department of Sexology, Montreal, Canada.

Background: Sexual aversion (SA) is a chronic difficulty impacting sexual, relational and psychological wellbeing. Yet, there is a dearth of studies exploring its prevalence and associated factors.

Aim: To estimate the prevalence of SA and examine its correlates among a community sample of Canadian adults. Read More

Eur Urol 2022 Jun 21. Epub 2022 Jun 21.

Department of Surgical Sciences, University of Turin and Città della Salute e della Scienza, Turin, Italy.

Background: Despite an expected increase in prostate cancer (PCa) incidence in the renal transplant recipient (RTR) population in the near future, robot-assisted radical prostatectomy (RARP) in these patients has been poorly detailed. It is not well understood whether results are comparable to RARP in the non-RTR setting.

Objective: To describe the surgical technique for RARP in RTR and report results from our multi-institutional experience. Read More

Curr Probl Cancer 2022 Jun 20:100881. Epub 2022 Jun 20.

Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; Allergy and Clinical Immunology Unit, Center for the diagnosis and treatment of Osteoporosis, AUSL 04 Teramo, Italy; Technical group for the coordination of Gender Medicine, Regione Abruzzo, Italy. Electronic address:

Immunity 2022 Jun 8. Epub 2022 Jun 8.

Infection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC 3000, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, VIC 3000, Australia; Department of General Medicine, Royal Children's Hospital Melbourne, Melbourne, VIC 3000, Australia.

As the establishment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell memory in children remains largely unexplored, we recruited convalescent COVID-19 children and adults to define their circulating memory SARS-CoV-2-specific CD4 and CD8 T cells prior to vaccination. We analyzed epitope-specific T cells directly ex vivo using seven HLA class I and class II tetramers presenting SARS-CoV-2 epitopes, together with Spike-specific B cells. Unvaccinated children who seroconverted had comparable Spike-specific but lower ORF1a- and N-specific memory T cell responses compared with adults. Read More

Domest Anim Endocrinol 2022 Jun 2;81:106746. Epub 2022 Jun 2.

UMR Physiologie de la Reproduction et des Comportements, INRAE, CNRS, IFCE, Université de Tours, Agreenium, 37380 Nouzilly, France.

Male goats rendered sexually active by exposure to a photoperiodic treatment are more efficient than untreated goats in stimulating LH secretion and ovulation in seasonally anestrous goats. This phenomenon is called the "male effect." Here, we determined whether sexually active bucks are able to stimulate the endocrine and sexual activities of other bucks in seasonal sexual rest through the phenomenon that we called the "buck-to-buck effect. Read More

West Afr J Med 2022 Jun;39(6):595-602

Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.

Background: Cervical cancer is the second leading cause of female cancer deaths in Nigeria. Routine cervical cancer screening and early treatment can prevent up to 80% of cervical cancers. This study was carried out to assess the knowledge, risk factors and practice of cervical cancer screening among women residing in urban slums of Lagos, Nigeria. Read More

J Psychosom Obstet Gynaecol 2022 Jun 24:1-6. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology in Norrköping, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Most studies of fear of childbirth (FOC) are conducted on heterosexual cisgender pregnant populations of birth-giving parents. Among lesbian and bisexual women, as well as transgender and queer people (LBTQ), minority stress can add an extra layer to FOC. Gender binary and cisnormative assumptions leave it to the patient to educate and navigate healthcare providers, which can increase mental health problems. Read More

Genome Biol Evol 2022 Jun 23. Epub 2022 Jun 23.

School of BioSciences, The University of Melbourne, Melbourne, Victoria 3010, Australia.

Genomic imprinting is found in marsupial and eutherian mammals, but not in monotremes. While the primary regulator of genomic imprinting in eutherians is differential DNA methylation between parental alleles, conserved imprinted genes in marsupials tend to lack DNA methylation at their promoters. DNA methylation at eutherian imprinted genes is mainly catalysed by a DNA methyltransferase (DNMT) enzyme, DNMT3A. Read More

Sex Reprod Health Matters 2021 ;29(2):2083813

Health Systems Specialist, United Nations Population Fund (UNFPA), Dhaka, Bangladesh.

Across low- and middle-income countries, investment in adolescent sexual and reproductive health (ASRH) is growing. However, the lack of comprehensive ASRH data hinders programmes. This mapping review examines the available evidence on ASRH in Bangladesh and points out the areas where critical information gaps exist. Read More

Glob Public Health 2022 Jun 24:1-15. Epub 2022 Jun 24.

Faculty of Medicine, Community Health Department, Sexual and Reproductive Health Unit, Eduardo Mondlane University, Maputo, Mozambique.

Measures to contain the spread of COVID-19 have been shown to disproportionately affect the marginalised groups in our societies. We studied the impacts of national restrictions on young adult sex workers in Mozambique, and actions at individual, governmental and civil society level to mitigate against these impacts. The country case study was part of a multi-country qualitative research, including fifty-four semi-structured interviews with female sex workers ( = 38), outreach workers ( = 10) in Maputo and Quelimane, and informants with key positions in national COVID coordination bodies, the Ministry of Health and civil society organisations ( = 7). Read More

J Viral Hepat 2022 Jun 24. Epub 2022 Jun 24.

Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Liver Int 2022 Jun 24. Epub 2022 Jun 24.

Public Health Regional Laboratory, Hospital Isabel Zendal, Madrid, Spain.

Hepatitis delta virus (HDV) is a defective agent that only infects individuals with hepatitis B virus (HBV). Around 5-10% of chronic hepatitis B patients worldwide are superinfected with HDV, which means 15-25 million people. Hepatitis delta is the most severe of all chronic viral hepatitis, leading to cirrhosis, liver cancer and/or transplantation in most patients. Read More