2,997 results match your criteria severe urethral


Impact of a mid-urethral synthetic mesh sling on long-term risk of systemic conditions in women with stress urinary incontinence: a national cohort study.

BJOG 2021 Sep 15. Epub 2021 Sep 15.

British Society of Urogynaecology, UK.

Objective: To compare the incidence of systemic conditions between women who had surgical treatment for stress incontinence with mesh and without mesh.

Design: National cohort study.

Setting: English National Health Service. Read More

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September 2021

Mid-term results of the Remeex® readjustable sling for female complex stress urinary incontinence and sonographic hypomobile urethra.

Int Urogynecol J 2021 Sep 10. Epub 2021 Sep 10.

Pelvic Floor Unit, ICGON, Hospital Clínic de Barcelona, University of Barcelona, Villarroel 170, 08036, Barcelona, Spain.

Introduction And Hypothesis: We aimed to evaluate the results of a readjustable sling (Remeex® system) among a selected group of women with complex stress urinary incontinence (SUI) with sonographic hypomobile urethra and assessing failure-related risk factors.

Methods: Observational, longitudinal, prospective cohort study, including patients who underwent surgery with the Remeex® system. The primary outcome was a binary outcome in change of one level or more of the severity of urinary incontinence symptoms according to the intervals of the Incontinence Questionnaire-Short Form (ICIQ-UI-SF) score (mild, moderate, severe and very severe). Read More

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September 2021

Traumatic penile partial amputation caused by rubber band a case report.

Int J Surg Case Rep 2021 Sep 31;86:106358. Epub 2021 Aug 31.

Division of Urology, Faculty of Medicine University of Padjadjaran, Hasan Sadikin Hospital Bandung, Jalan Pasteur no 38, Bandung 40161, Indonesia.

Introduction And Importance: Traumatic amputation of the penis is a rare surgical emergency. Penile amputation is usually caused by self-mutilation, accidents, circumcision, assault and animal attacks. Accidental injury covers a large portion of external genitalia trauma because of its high prevalence and severity of this disease. Read More

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September 2021

Single-stage versus staged interposition urethroplasty for glandular hypospadias with severe penile curvature: 15-year experience.

World J Urol 2021 Sep 5. Epub 2021 Sep 5.

Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children's Hospital, Futian District, Shenzhen, 518000, Guangdong, People's Republic of China.

Purpose: Our study examined the benefit of an alternative interposition urethroplasty (IU) procedure for glandular hypospadias (GH) with severe penile curvature (SPC). The technique involved transecting and reconstructing the urethra to preserve the distal glandular and coronal urethra and correct the curvature. We compared procedural characteristics, outcomes, and surgical complications for the single-stage and staged IU techniques. Read More

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September 2021

Long-term efficacy and complications of a multicentre randomised controlled trial comparing Retropubic and Transobturator Mid-Urethral Slings: a prospective observational study.

BJOG 2021 Sep 3. Epub 2021 Sep 3.

University Hospital Plymouth NHS Trust.

Objective: Concerns exist regarding the risks of mid-urethral slings (MUS) for stress urinary incontinence (SUI), particularly the lack of long-term data. We compare patient reported outcomes of a multicentre randomised controlled trial of retropubic (TVT-GYNECARE ) versus transobturator (TOT-MONARC ) tape surgery at 12 years.

Design And Setting: A multicentre study was performed in 11 tertiary referral centres. Read More

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September 2021

Quantitative evaluation of upper urinary tract pump function in pigs with acute unilateral lower ureteral obstruction by 640-slice dynamic volume CT.

BMC Urol 2021 Sep 2;21(1):118. Epub 2021 Sep 2.

Department of Radiology, The Fourth Affiliated Hospital of Kunming Medical University, #176 Qingnian Road, Kunming, 650021, Yunnan, China.

Background: It is a challenging problem to differentiate obstructive hydronephrosis from noninvasive evaluation of renal pelvis and ureteral motility in patients. The purpose of this study was to explore the value of 640-slice dynamic volume CT (DVCT) in the quantitative measurement of upper urinary tract (UUT) pump function after acute unilateral lower ureteral obstruction in pigs.

Methods: In this study, a perfusion pig model was constructed by constant pressure perfusion testing of the renal pelvis and left nephrostomy. Read More

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September 2021

Prospective Assessment of Patient-Perceived Short-Term Changes in Penile Appearance After Urethroplasty.

Urology 2021 Aug 27. Epub 2021 Aug 27.

Division of Urology, University of Alberta, Edmonton, Alberta. Electronic address:

Objective: To define the incidence and associations of patient-reported penile curvature and shortening after urethroplasty. Alterations in penile curvature or length post-urethroplasty are associated with patient dissatisfaction but are poorly described.

Methods: From 2011-2019, 387 patients completed enrollment in a prospective single-centre study assessing patient-reported outcomes pre-operatively and 6-months post-urethroplasty. Read More

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Medical device-related pressure injuries in critical patients: prevalence and associated factors.

Rev Esc Enferm USP 2021 23;55:e20200397. Epub 2021 Aug 23.

Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Enfermagem, Departamento de Enfermagem, Florianópolis, SC, Brazil.

Objective: To determine the prevalence of medical device-related pressure injuries in critical patients and analyze the associated factors.

Method: Epidemiological, cross-sectional study. Sociodemographic, clinical and medical device data were collected. Read More

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Prostatic Artery Embolization: Indications, Preparation, Techniques, Imaging Evaluation, Reporting, and Complications.

Radiographics 2021 Sep-Oct;41(5):1509-1530. Epub 2021 Aug 20.

From the Departments of Radiology (U.S.D., M.R.L.d.M., P.C.C.V., A.S.Z.M., C.C.L., G.G.C.) and Interventional Radiology (M.R.L.d.M., P.C.C.V., A.M.d.A., A.M.M., F.C.C.), Hospital Sírio-Libanês, Adma Jafet 91, Bela Vista, São Paulo, SP 01308-050, Brazil; Departments of Radiology (M.R.L.d.M., P.C.C.V., C.C.L., G.G.C.) and Interventional Radiology (M.R.L.d.M., P.C.C.V., A.M.d.A., A.M.M., F.C.C.), University of São Paulo, São Paulo, Brazil; and Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (N.H.).

Benign prostatic hyperplasia (BPH) is a noncancerous growth of the transitional zone of the prostate, which surrounds the prostatic urethra. Consequently, it can cause lower urinary tract symptoms (LUTS) and bladder outlet obstruction symptoms that may substantially reduce a patient's quality of life. Several treatments are available for BPH, including medications such as α-blockers and 5α-reductase inhibitors and surgical options including transurethral resection of the prostate and prostatectomy. Read More

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A comparison of artificial urinary sphincter outcomes after primary implantation and first revision surgery.

Asian J Urol 2021 Jul 13;8(3):298-302. Epub 2021 Mar 13.

Department of Urology, Mayo Clinic, Rochester, MN, USA.

Objective: The artificial urinary sphincter (AUS) is the gold standard for severe male stress urinary incontinence, though evaluations of specific predictors for device outcomes are sparse. We sought to compare outcomes between primary and revision AUS surgery for non-infectious failures.

Methods: We identified 2045 consecutive AUS surgeries at Mayo Clinic (Rochester, MN, USA) from 1983 to 2013. Read More

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Asian guidelines for urinary tract infection in children.

J Infect Chemother 2021 Nov 11;27(11):1543-1554. Epub 2021 Aug 11.

Department of Urology, Uijeongbu ST. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Republic of Korea.

The followings are the level of evidence (LE) and grade of recommendation (GR) on pediatric UTI in Asia. Classification according to the sites of infection (lower versus upper tract), the number of episode (first versus recurrent), the severity (simple versus severe), or the existence of complicating factor (uncomplicated versus complicated) is useful to differentiate children with UTI whether they are at risk of renal damage or not (LE: 2, GR: B). Diagnosis of UTI requires both urinalysis that suggests infection and positive urine culture (LE:3, GR B). Read More

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November 2021

Reactive arthritis: images.

Dermatol Online J 2021 Jul 15;27(7). Epub 2021 Jul 15.

Department of Oral Pathology and Medicine, Faculty of Dentistry, University of Chile, Santiago.

Reactive arthritis is an extremely rare spondyloarthritis that affects the peripheral joints and spine, resulting in common symptoms such as arthritis, urethritis, conjunctivitis, and mucocutaneous lesions. On rare occasions, oral lesions such as circinate erosions on the hard and soft palate, gums, tongue, and cheeks may occur. Reactive arthritis may develop during or after genitourinary or gastrointestinal bacterial infections such as Shigella, Salmonella, Yersinia, and Chlamydia. Read More

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Temporal trends in the incidence of severe pelvic fracture urethral injuries in the United States from 1998 to 2014.

World J Urol 2021 Aug 12. Epub 2021 Aug 12.

Division of Urology, Duke University Medical Center, Durham, NC, USA.

Object: To use a contemporary population-based cohort to investigate temporal trends in the national incidence of pelvic fracture urethral injuries (PFUIs) in the United States.

Methods: Using the NIS (National Inpatient Sample), we identified patients with a severe PFUI by a combination of an ICD-9 diagnosis code for pelvic fracture (808.xx) and ICD-9 procedure code for suprapubic tube (57. Read More

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Preserving ejaculatory function in young patients with lower urinary tract symptoms: medium- to long-term follow-up of prostatic urethral lift at a single center.

Ther Adv Urol 2021 Jan-Dec;13:17562872211037109. Epub 2021 Jul 31.

Department of Urology and Organ Transplantation, University of Foggia, Policlinico Riuniti, Foggia, Italy.

Background And Aims: Prostatic urethral lift (Urolift™) is a minimally invasive technique to treat male lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH). The aim of the present study was to assess safety and medium- to long-term outcomes in the relief of urinary symptoms.

Methods: We included 35 men, affected by severe symptomatic BPH evaluated by International Prostate Symptom Score (IPSS), with normal erectile function (EF) and ejaculatory function (EjF) evaluated by the International Index of Erectile Dysfunction (IIEF-5) and Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD-SF). Read More

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Two simple modifications can potentially change the future of proximal hypospadias surgery. Our series and a review of the literature.

Int J Pediatr Adolesc Med 2021 Sep 9;8(3):172-176. Epub 2020 Jul 9.

39 Avenue de la Liberté, 68000, Colmar, France.

Background/objective: To draw a hint towards two simple modifications that could potentially decrease the complication rate.

Patients And Methods: It was a single center, single operator and retrospective study. All patients with severe hypospadias operated according to koyanagi with or without modifications were presented. Read More

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September 2021

Primary urethral carcinoma: Results from a single center experience.

Actas Urol Esp 2021 Jul 28. Epub 2021 Jul 28.

Departamento de Urología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España.

Introduction And Aim Of The Study: Primary urethral carcinoma (PUC) is a rare neoplastic disease arising in the urethra, without any evidence of a previous or synchronous carcinoma of the entire urinary tract. Since rare diseases are often incorrectly diagnosed and managed, the aim of this study was to analyze the experience of a single urology center in the treatment of PUC, focusing on neoplasms arising from the male anterior urethra.

Materials And Methods: Medical records of patients with neoplasms at the level of the penile and bulbar urethra who presented at our tertiary referral center between January 1988 and December 2018 were retrospectively reviewed. Read More

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Aquablation, Prostatic Urethral Lift, and Transurethral Water Vapor Therapy: A Comparison of Device Related Adverse Events in a National Registry.

J Endourol 2021 Jul 27. Epub 2021 Jul 27.

Maimonides Medical Center, 2042, Brooklyn, New York, United States;

Purpose: Aquablation, prostatic urethral lift (PUL), and transurethral water vapor therapy (TWVT) have demonstrated efficacy for the treatment of benign prostatic hyperplasia (BPH). Our objective was to describe device malfunctions and complications to help guide procedural selection and performance.

Materials And Methods: The Manufacturer and User Facility Device Experience (MAUDE) database was examined for reports related to the use of these three procedures for the treatment of BPH between January 1, 2015 and July 1, 2020. Read More

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A Systematic Review of Radiation-Related Lymphopenia in Genito-urinary Malignancies.

Cancer Invest 2021 Oct 17;39(9):769-776. Epub 2021 Aug 17.

Department of Radiation Oncology, Loyola University, Chicago, IL, USA.

Background: The impact of radiation-related lymphopenia on clinical outcomes has been reported in various solid malignancies such as high grade gliomas, head and neck cancers, thoracic malignancies and gastro-intestinal malignancies but its impact is not clearly known in the context of common genito-urinary (GU) malignancies.

Methodology: To better understand the effect of radiation-associated lymphopenia in prostate and bladder cancer, we undertook this systematic review of clinical studies that have studied radiation-related lymphopenia in GU malignancies. A systematic methodology search of PubMed, Embase, and Cochrane library resulted in 2125 abstracts. Read More

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October 2021

Narrative review of penile distal urethroplasties and suggestions for optimizing outcomes.

Transl Androl Urol 2021 Jun;10(6):2609-2616

University of Lisbon, Lisbon, Portugal.

Distal urethral strictures can be a challenging entity for urologists. Endoscopic maneuvers such as optical internal urethrotomies or dilations are even less successful than in other urethral locations and the repeated trauma will increase the scarring which advocates for a urethroplasty as primary option for patient management. Success rates of distal urethroplasties have been lower than those for other urethral strictures due to the anatomy of the distal urethra with a very thin corpus spongiosum associated with decreased mucosal blood supply. Read More

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Sexual function after anterior urethroplasty: a systematic review.

Transl Androl Urol 2021 Jun;10(6):2554-2573

Urology Department, Marques de Valdecilla University Hospital, Santander, Spain.

Background: Urethral surgery outcomes are often evaluated by assessing urinary flow and urethral patency. However, sexual consequences may appear after urethroplasty, impairing quality of life and patient's perception of success.The aim of this study is to assess the relationship between anterior urethral reconstruction and postoperative sexual dysfunction, including the proposed factors predicting sexual outcomes. Read More

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Neoadjuvant chemotherapy followed by radical surgery in locally advanced vulvar carcinoma: a single-institution experience.

Tumori 2021 Jul 21:3008916211027627. Epub 2021 Jul 21.

Gynaecologic Oncology Surgical Unit, Obstetrics and Gynaecology Department, ASST-Monza, San Gerardo Hospital, Monza, Lombardia, Italy.

Background: Squamous cell carcinoma of the vulva is a rare malignancy that affects elderly women. About one-third of vulvar cancers are diagnosed in an advanced stage, requiring extensive surgery. Neoadjuvant chemotherapy (NACT) has been introduced to reduce local tumor burden. Read More

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Management of Disastrous Complications of Penile Implant Surgery.

J Sex Med 2021 07;18(7):1145-1157

Department of Urology, University College London Hospitals & St Peters Andrology Centre, London, UK.

Rationale: Penile Prosthesis Implantation (PPI) is the definitive treatment for Erectile Dysfunction not responsive to conservative management strategies. Furthermore, it is a staple of surgical treatment of severe Peyronie's Disease (PD) and phallic reconstruction. Expert implantologists occasionally face disastrous complications of penile implant surgery which can prove to be very challenging. Read More

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Long-term followup of two-sided dorsal plus ventral oral graft bulbar urethroplasty: single center experience on 216 patients.

Minerva Urol Nephrol 2021 Jul 15. Epub 2021 Jul 15.

Department of Urology, Hesperia Hospital, CURE Group, Modena, Italy.

Background: Two-sided dorsal plus ventral oral graft urethroplasty is a new urethra-sparing technique suggested in tight bulbar strictures which are too severe for a simple one-side grafting. The aim is to evaluate long-term outcomes and the success predictive factors of this technique.

Methods: A descriptive retrospective study was conducted on 216 patients undergone dorsal plus ventral graft urethroplasty for bulbar strictures between 2002 and 2018 in a single high-volume center by a single surgeon (EP). Read More

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Stage-dependent function of Wnt5a during male external genitalia development.

Congenit Anom (Kyoto) 2021 Jul 13. Epub 2021 Jul 13.

Department of Developmental Genetics, Institute of Advanced Medicine, Wakayama Medical University, Wakayama, Japan.

External genitalia development in mice involves multiple developmental processes under the regulation of various signaling pathways. Wnt5a, one of the major Wnt ligands, is a crucial developmental regulator of outgrowing organs such as the limb, the mandible, and the external genitalia. Defects in Wnt5a signaling have been linked to Robinow syndrome, a genetic disorder in which male patients manifest a micropenis and defective urethral tube formation. Read More

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Cranial translation of the elevated prepuce in dogs before and after two modifications: A cadaveric study.

Vet Surg 2021 Jul 9. Epub 2021 Jul 9.

Hebrew University of Jerusalem, Koret School of Veterinary Medicine, Robert H Smith Faculty of Agriculture Food & Environment, Rehovot, Israel.

Objective: To quantify cranial translation of the prepuce after elevating it from the ventral body wall and to compare it to the cranial translation achieved after each of two modifications expected to increase cranial translation.

Study Design: Cadaveric study.

Sample Population: Ten male dogs. Read More

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Creation of Tissue-Engineered Urethras for Large Urethral Defect Repair in a Rabbit Experimental Model.

Front Pediatr 2021 22;9:691131. Epub 2021 Jun 22.

Department of Women's and Children's Health, Bioclinicum J10:20, Karolinska Institutet, Stockholm, Sweden.

Tissue engineering is a potential source of urethral substitutes to treat severe urethral defects. Our aim was to create tissue-engineered urethras by harvesting autologous cells obtained by bladder washes and then using these cells to create a neourethra in a chronic large urethral defect in a rabbit model. A large urethral defect was first created in male New Zealand rabbits by resecting an elliptic defect (70 mm) in the ventral penile urethra and then letting it settle down as a chronic defect for 5-6 weeks. Read More

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Anal canal to pubis angle: a novel clinical ultrasound technique for the assessment of the anorectal region.

Int Urogynecol J 2021 Sep 8;32(9):2421-2427. Epub 2021 Jul 8.

St Mary's hospital, Imperial College Healthcare NHS Trust, Paddington, W2 1NY, UK.

Introduction And Hypothesis: Posterior compartment prolapse is associated with severe morbidity including faecal incontinence and defaecation dysfunction. The aim of this study was to develop and validate a novel ultrasound marker (anal canal to pubis angle) for the assessment of the anal axis in the context of posterior compartment prolapse in women and in controls (healthy, nulliparous, non-pregnant volunteers).

Methods: Anal canal to pubis (AC/Pubis) angle is measured with 2D transperineal ultrasound in precisely the midsagittal plane. Read More

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September 2021

Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease.

Int Heart J 2021 Jul 6;62(4):935-937. Epub 2021 Jul 6.

Department of Pediatrics, Miyazaki Prefectural Miyazaki Hospital.

Spontaneous spinal epidural hematoma (SSEH) is considered to be a relatively rare disease that can result in serious neurological sequelae. The pathogenesis and risk factors of SSEH are still unknown, and its differential diagnosis varies widely. Misdiagnosis with more common conditions such as stroke or aortic syndromes can occur. Read More

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Long-term outcome of urethral and genital reconstruction in hypospadias and exstrophy-epispadias complex.

Curr Opin Urol 2021 Sep;31(5):480-485

Department of Urology, ERN eUROGEN Accredited Centre, Ghent University Hospital.

Purpose Of Review: Although immediate surgical outcomes of genitourinary reconstruction used to be the main focus in hypospadias and exstrophy-epispadias complex (EEC), recent research demonstrates rising concerns about long-term functional and psychosexual outcomes. Recent results about long-term outcomes of complex genitourinary reconstruction in those children transitioning into adulthood are summarized and discussed in this comprehensive review.

Recent Findings: Long-term outcomes in hypospadias focus on psychosexual satisfaction and decisional regret. Read More

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September 2021

Association between overactive bladder and pelvic organ mobility as evaluated by dynamic magnetic resonance imaging.

Sci Rep 2021 Jul 2;11(1):13726. Epub 2021 Jul 2.

Department of Urology, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda City, Tokyo, 102-0084, Japan.

Overactive bladder (OAB) is a prevalent condition, which negatively impacts patients' quality of life. Pelvic organ prolapse (POP), also prevalent in women, has been recognized as an important etiology of female OAB, although the pathophysiological mechanisms remain controversial. In this study, we reviewed findings of dynamic magnetic resonance imaging (dMRI) in 118 patients with POP and investigated the association between dMRI findings, including positions and mobilities of pelvic organs as well as parameters of pelvic organ support and bladder outlet obstruction (urethral kinking), and OAB in order to elucidate the pathophysiology of OAB in patients with POP. Read More

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