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Hands-On Workshops Improve Emergency Department Physicians' Self-Reported Understanding of Pediatric Hand Injuries.

Pediatr Emerg Care 2021 May 18. Epub 2021 May 18.

From the University of Ottawa Divisions of Plastic Surgery Emergency Medicine, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

Objectives: The aims of this study were to assess emergency department (ED) physician perception of hand injuries and improve their understanding and confidence in treating these injuries.

Methods: Combined didactic and hands-on workshops for ED physicians were developed and run by a team of medical students, plastic surgeons, and ED physicians. The workshops consisted of a short review by a hand surgeon followed by hands-on sessions involving radiograph assessment, administration of local anesthetic, closed reduction, and splinting. Read More

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Effects of pulsed ultrasound on olfactory dysfunction in patients with chronic rhinosinusitis: A pilot study.

Complement Ther Clin Pract 2021 Jun 5;44:101409. Epub 2021 Jun 5.

Department of Physical Therapy, Augusta University, Augusta, GA, USA.

Background: and purpose. Olfactory dysfunction is a common symptom of chronic rhinosinusitis (CRS). This study aimed to evaluate the effects of therapeutic pulsed ultrasound (PUS) on olfactory dysfunction in patients with CRS. Read More

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Clinical evaluation of in-office tooth whitening with violet LED (405 nm): A double-blind randomized controlled clinical trial.

Photodiagnosis Photodyn Ther 2021 Jun 8:102385. Epub 2021 Jun 8.

Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, UNINOVE, São Paulo, Brazil. Electronic address:

Background: Although there is little evidence showing the effectiveness of violet LED on in-office tooth whitening, there are some studies which have reported satisfactory results. This double-blind randomized controlled clinical trial aimed to evaluate the effect of a violet light emission diode (LED) (405nm) system, used in-office, on tooth whitening, sensitivity, use of medication after whitening and quality of life.

Methods: Eight patients were randomized into 4 groups (n = 20): G1 - violet LED, G2 - 35% carbamide peroxide (CP) and violet LED, G3 only CP 35% and G4 35% hydrogen peroxide (HP). Read More

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A tailored telehealth group tobacco cessation treatment program for people with HIV: Study protocol for a randomized controlled trial.

Contemp Clin Trials 2021 Jun 8:106475. Epub 2021 Jun 8.

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, United States of America. Electronic address:

Background: Smoking-related illnesses are the leading cause of death among people with HIV (PWH). Yet, there are few effective evidence-based interventions that help PWH quit smoking. The group-based program Positively Smoke Free is a biobehavioral cessation intervention for PWH with a growing evidence base. Read More

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Decomposition of individual-specific and individual-shared components from resting-state functional connectivity using a multi-task machine learning method.

Neuroimage 2021 Jun 8:118252. Epub 2021 Jun 8.

School of Biological Science & Medical Engineering, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.

Resting-state functional connectivity (RSFC) can be used for mapping large-scale human brain networks during rest. There is considerable interest in distinguishing the individual-shared and individual-specific components in RSFC for the better identification of individuals and prediction of behavior. Therefore, we propose a multi-task learning based sparse convex alternating structure optimization (MTL-sCASO) method to decompose RSFC into individual-specific connectivity and individual-shared connectivity. Read More

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Chronic levetiracetam (Keppra®) treatment increases the reinforcing strength of cocaine in rhesus monkeys.

Pharmacol Biochem Behav 2021 Jun 8:173217. Epub 2021 Jun 8.

Department of Physiology & Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157-1083, United States of America.

Background: Drugs that increase inhibitory neuronal activity in the brain have been proposed as potential medications for stimulant use disorders.

Objective: The present study assessed the ability of chronically administered levetiracetam (Keppra®), a clinically available anticonvulsant drug that increases GABA by binding to synaptic vesicle glycoprotein 2A, to modulate the reinforcing strength of cocaine in monkeys.

Methods: Three adult male rhesus monkeys (Macaca mulatta) self-administered cocaine intravenously each day under a progressive-ratio (PR) schedule of reinforcement. Read More

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Endoscopy Training in Small Animal Internal Medicine: A Survey of Residency Training Programs in North America.

J Vet Med Educ 2021 Jun 11:e20200165. Epub 2021 Jun 11.

Competency in multiple endoscopic techniques is a major goal of small animal internal medicine (SAIM) residency programs. Training relies predominantly on mentored supervision of procedures performed on patients. Supplementation of this apprenticeship model with classroom sessions and hands-on laboratories can be advantageous to trainees and patients. Read More

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Comparison of equine synovial sepsis rate following intrasynovial injection in ambulatory versus hospital settings.

Equine Vet J 2021 Jun 11. Epub 2021 Jun 11.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, Colorado, 80523, USA.

Background: Frequency of synovial sepsis in horses following intrasynovial injection has been reported, but not compared with respect to environment in which the injection was performed.

Objectives: To describe occurrence of synovial sepsis following intrasynovial injections performed in ambulatory versus hospital settings.

Study Design: Retrospective cohort study. Read More

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Acceptance and commitment therapy for high frequency episodic migraine without aura: Findings from a randomized pilot investigation.

Headache 2021 Jun 11. Epub 2021 Jun 11.

UO Neurologia Salute Pubblica e Disabilità, Fondazione IRRCS Istituto Neurologico Carlo Besta, Milano, Italy.

Objective: We compared the incremental effects of adding acceptance and commitment therapy (ACT) to pharmacological treatment as usual (TAU) in a sample of patients with high frequency episodic migraine without aura (HFEM), assessing impact on a spectrum of measures across multiple domains.

Background: Patients with HFEM are at risk of developing chronic migraine and medication overuse headache. ACT has been shown to be effective for the treatment of various chronic pain conditions, but little attention has been given to its therapeutic value in the management of recurring headaches. Read More

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Day versus night consolidation of implicit sequence learning using manual and oculomotor activation versions of the serial reaction time task: reaction time and anticipation measures.

Psychol Res 2021 Jun 11. Epub 2021 Jun 11.

Department of Psychology, Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Bar-Ilan University, 52900, Ramat-Gan, Israel.

This study presents two experiments that explored consolidation of implicit sequence learning based on two dependent variables-reaction time (RT) and correct anticipations to clarify the role of sleep, and whether the manual component is necessary for consolidation processes. Experiment 1 (n = 37) explored the performance of adults using an ocular variant of the serial reaction time task (O-SRT) with manual activation (MA), and Experiment 2 (n = 37) used the ocular activation (OA) version of the task. Each experiment consisted of a Day and a Night group that performed two sessions of the O-SRT with an intervening 12-h offline period (morning/evening in Day group, evening/following morning in Night group). Read More

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The tolerance of physiotherapy treatment in patients with COVID-19 and undergoing surgery for fragility hip fracture: An observational study.

Medicine (Baltimore) 2021 Jun;100(23):e26283

IRCCS Istituto Ortopedico Rizzoli, Via Pupilli 1, Bologna, Italy.

Abstract: The aim of the present work was to evaluate the tolerance of physiotherapy treatment implemented for patients with coronavirus disease (COVID-19) and undergoing hip surgeryCase-control study. During the period between March and May 2020, 9 patients were enrolled in the study with diagnosis of COVID-19 and hip fracture. In order to evaluate the tolerability of physiotherapy treatment a comparison group, involving 27 patients with a hip fracture but in the absence of suspicion of COVID-19 positivity, were put together. Read More

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Blood pressure-lowering effect of repeated Waon therapy in non-smokers with hypertension.

Medicine (Baltimore) 2021 Jun;100(23):e26266

Cardiac Rehabilitation Center.

Abstract: Waon therapy (WT) has been used as a thermal therapy in chronic heart failure patients. However, its effect in patients with hypertension is unclear. This study aimed to reveal the hypotensive effect of WT in patients with hypertension. Read More

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Feasibility and Acceptability of a Mobile Phone App Intervention for Coping With Cancer as a Young Adult: Pilot Trial and Thematic Analysis.

J Med Internet Res 2021 Jun 11;23(6):e25069. Epub 2021 Jun 11.

Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, United States.

Background: Many young adult patients do not receive adequate psychosocial services to help them cope with cancer.

Objective: This study aims to assess the feasibility and acceptability of a smartphone app (iaya) intervention that was designed to create an engaged community of young adult patients and help them learn emotional coping skills.

Methods: For this single-group pilot trial, 25 young adult patients aged 18-39 years who were receiving active cancer treatment were asked to use the iaya app for 12 weeks. Read More

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Post-stress glucose consumption facilitates hormesis and resilience to severe stress.

Stress 2021 Jun 11:1-7. Epub 2021 Jun 11.

Departmentof Psychology, University of California, Los Angeles, CA, USA.

Oral ingestion of a glucose solution following severe stress is a simple and effective way of preventing several of the negative sequelae of stress in rats. Similar resilience is obtained through hormetic training - pre-exposure to mild-to-moderate stress prior to severe stress. Here, we examined whether hormetic training is facilitated when a glucose solution is available following each hormetic training session. Read More

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Rapid Curricular Innovations During COVID-19 Clinical Suspension: Maintaining Student Engagement with Simulation Experiences.

J Midwifery Womens Health 2021 Jun 11. Epub 2021 Jun 11.

Department of Advanced Nursing Practice, Georgetown University School of Nursing and Health Studies, Washington, District of Columbia.

Health care education programs were faced with the need to quickly adapt to a new reality during the coronavirus disease 2019 pandemic. Students were temporarily suspended from campus and clinical sites, requiring prompt changes in structure to their didactic and clinical learning. This article describes the rapid adjustments that one midwifery and women's health nurse practitioner education program created using both synchronous and asynchronous simulation experiences to promote student learning and ongoing engagement. Read More

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Lesser-Known Aspects of Deep Brain Stimulation for Parkinson's Disease: Programming Sessions, Hardware Surgeries, Residential Care Admissions, and Deaths.

Neuromodulation 2021 Jun 10. Epub 2021 Jun 10.

Bionics Institute, East Melbourne, VIC, Australia.

Objective: The long-term treatment burden, duration of community living, and survival of patients with Parkinson's disease (PD) after deep brain stimulation (DBS) implantation are unclear. This study aims to determine the frequency of programming, repeat hardware surgeries (of the intracranial electrode, implantable pulse generator [IPG], and extension-cable), and the timings of residential care and death in patients with PD treated with DBS.

Materials And Methods: In this cross-sectional, population-based study, individual-level data were collected from the Australian government covering a 15-year period (2002-2016) on 1849 patients with PD followed from DBS implantation. Read More

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Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder.

J Trauma Stress 2021 Jun 10. Epub 2021 Jun 10.

Psychedelic Support, Santa Cruz, California, USA.

Sleep disturbances (SDs) are among the most distressing and commonly reported symptoms in posttraumatic stress disorder (PTSD). Despite increased attention on sleep in clinical PTSD research, SDs remain difficult to treat. In Phase 2 trials, 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy has been shown to greatly improve PTSD symptoms. Read More

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The effect of combined cognitive-behavioral psychoeducation and music intervention on stress, self-efficacy, and relapse rates in patients with alcohol and substance use disorders: A randomized controlled trial.

Perspect Psychiatr Care 2021 Jun 10. Epub 2021 Jun 10.

Department of Psychiatric Nursing, Faculty of Nursing, Ataturk University, Erzurum, Turkey.

Purpose: This study was conducted to determine the effect of psychoeducation and music intervention on stress, self-efficacy, and relapse rates in alcohol and substance use disorders.

Design And Methods: This was a randomized controlled study. The study sample included 62 patients who met the inclusion criteria. Read More

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A structured Endoscopic Ultrasound training program in Germany improves knowledge and competence.

Med Ultrason 2021 Jun 10. Epub 2021 Jun 10.

Institut for Medical Education, University Hospital of LMU Munich, Munich, Germany.

Aims: Limited evidence on how to organize pre-patient training in Endoscopic Ultrasound (EUS) and how to evaluate its effect on knowledge and skills are available. The aim of our study was to assess the impact of a structured multi-site training program on EUS competence in Germany.

Material And Methods: In a prospective study design, evaluation of 64 trainees was conducted during four three-day training courses with equal curricula at three sites. Read More

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Involving patients as key stakeholders in the design of cardiovascular implantable electronic device data dashboards: Implications for patient care.

Heart Rhythm O2 2020 Jun 11;1(2):136-146. Epub 2020 May 11.

Parkview Mirro Center for Research and Innovation, Parkview Health, Fort Wayne, Indiana.

Background: Data from remote monitoring (RM) of cardiovascular implantable electronic devices (CIEDs) currently are not accessible to patients despite demand. The typical RM report contains multiple pages of data for trained technicians to read and interpret and requires a patient-centered approach to be curated to meet individual user needs.

Objective: The purpose of this study was to understand which RM data elements are important to patients and to gain design insights for displaying meaningful data in a digital dashboard. Read More

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How do political coups disrupt Fiji's tourism? Impact assessment on ecotourism at Koroyanitu National Heritage Park (KNHP), Abaca.

Heliyon 2021 May 28;7(5):e07101. Epub 2021 May 28.

Department of Social Science, College of Humanities and Education, Fiji National University, Natabua, Lautoka, PB 5529, Fiji.

The nexus between mass tourism and politics has been widely validated in tourism literature; nonetheless, the impacts of political putsches on ecotourism are understudied in the context of the Pacific Islands, i.e., Fiji. Read More

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Efficiency of an Optimized Care Organization in Fibromyalgia Patients: The From Intent to Move (FIMOUV) Study Protocol of a Randomized Controlled Trial.

Front Public Health 2021 25;9:554291. Epub 2021 May 25.

University Lyon, UJM-Saint-Etienne Sainbiose Laboratory, INSERM U1059, Saint-Étienne, France.

Fibromyalgia (FM) is characterized by multiple symptoms including pain, fatigue, and sleep disorders, altering patient's quality of life. In the absence of effective pharmacological therapy, the last European guidelines recommend a multidisciplinary management based on exercise and education. Thus, our main objective was to measure the effectiveness of a healthcare organization offering a specific program of adapted physical activity combined with a therapeutic education program for FM patients. Read More

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Efficacy of Short Course of Preksha Dhyana for Functional Abdominal Pain Disorder in a Busy Pediatric Clinic.

Front Pediatr 2021 25;9:646686. Epub 2021 May 25.

Department of Pediatric Gastroenterology and Nutrition, Orlando Health-Arnold Palmer Hospital for Children, Orlando, FL, United States.

Mind body techniques such as meditation improve symptoms in children and adults with IBS. Typical courses, however, are lengthy and difficult to administer. We report our experience with a short course of (PD), a child-friendly focused meditation with yoga. Read More

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Bilateral massive nephromegaly-A rare presentation of t-cell acute lymphoblastic leukemia.

Leuk Res Rep 2021 19;15:100246. Epub 2021 May 19.

Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

Introduction: Renal infiltration by leukemia causing massive bilateral nephromegaly is an extremely rare presentation of T-cell acute lymphoblastic leukemia(T-ALL).

Case Report: 18-month-old female toddler presented with fever and progressive abdominal distension of 4-6 weeks duration. Imaging revealed bilateral massively enlarged kidneys with normal excretion. Read More

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Preclinical evaluation of passive disinfection caps with a long-term catheter for the prevention of catheter-related bloodstream infection in pediatric cancer patients.

GMS Hyg Infect Control 2021 31;16:Doc20. Epub 2021 May 31.

Medical Solutions Division Laboratory, Europe, Middle East and Africa, 3M Deutschland GmbH, Neuss, Germany.

The use of passive disinfection devices (disinfection caps) may be a beneficial part of a maintenance care bundle, aiming at the prevention of catheter-related bloodstream infections in pediatric cancer patients. This preclinical investigation tested the visual and mechanical integrity of a Broviac™ catheter hub after simulation testing with 122 3M™ CurosTM Stopper Disinfection Caps for Open Female Luers repeatedly attached and removed over 6 months. We found that these catheter hubs were compatible, fully operational, and airtight with use of 3M Curos stopper caps after 6 months of use with 122 caps per catheter hub. Read More

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Using Technology to Identify Children With Autism Through Motor Abnormalities.

Front Psychol 2021 25;12:635696. Epub 2021 May 25.

Department of Humanistic Studies, University of Naples Federico II, Naples, Italy.

Autism is a neurodevelopmental disorder typically assessed and diagnosed through observational analysis of behavior. Assessment exclusively based on behavioral observation sessions requires a lot of time for the diagnosis. In recent years, there is a growing need to make assessment processes more motivating and capable to provide objective measures of the disorder. Read More

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Brain Networks Underlying Strategy Execution and Feedback Processing in an Efficient Functional Magnetic Resonance Imaging Neurofeedback Training Performed in a Parallel or a Serial Paradigm.

Front Hum Neurosci 2021 25;15:645048. Epub 2021 May 25.

School of Psychology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom.

Neurofeedback (NF) is a complex learning scenario, as the task consists of trying out mental strategies while processing a feedback signal that signifies activation in the brain area to be self-regulated and acts as a potential reward signal. In an attempt to dissect these subcomponents, we obtained whole-brain networks associated with efficient self-regulation in two paradigms: parallel, where the task was performed concurrently, combining feedback with strategy execution; and serial, where the task was performed consecutively, separating feedback processing from strategy execution. Twenty participants attempted to control their anterior midcingulate cortex (aMCC) using functional magnetic resonance imaging (fMRI) NF in 18 sessions over 2 weeks, using cognitive and emotional mental strategies. Read More

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Students' Perceptions and Attitudes After Exposure to Three Different Instructional Strategies in Applied Anatomy.

Adv Med Educ Pract 2021 4;12:607-612. Epub 2021 Jun 4.

Anatomy Department, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.

Background: The advancements of technologies have developed anatomical education into a new era. The study aims to assess medical students' performance and overall satisfaction who used the anatomage table and plastinated specimens for the teaching and learning anatomy courses.

Methods: A cross-sectional study was conducted on students of the first-year college of medicine at Imam Mohammad Ibn Saud Islamic University (IMSIU). Read More

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Brain training using cognitive apps can improve cognitive performance and processing speed in older adults.

Sci Rep 2021 Jun 10;11(1):12313. Epub 2021 Jun 10.

Department of Psychiatry and Behavioural and Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0SZ, UK.

Managing age-related decrease of cognitive function is an important public health challenge, especially in the context of the global aging of the population. Over the last years several Cognitive Mobile Games (CMG) have been developed to train and challenge the brain. However, currently the level of evidence supporting the benefits of using CMG in real-life use is limited in older adults, especially at a late age. Read More

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