Clin Orthop Relat Res 2021 04 29. Epub 2021 Apr 29.
A. Shahi, T. Nicholson, J. Abboud, M. Lazarus, G. Williams, J. Parvizi, S. Namdari, Department of Orthopaedic Surgery, the Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Background: The diagnosis of periprosthetic shoulder infection continues to be difficult to make with confidence. Serum D-dimer has proven to be effective as a screening tool for periprosthetic joint infection in other major joints; however, it has yet to be evaluated for use in periprosthetic shoulder infection.
Questions/purposes: (1) Is D-dimer elevated in patients with probable or definite periprosthetic shoulder infections? (2) What is the diagnostic accuracy of D-dimer for periprosthetic shoulder infections? (3) What are the diagnostic accuracies of serum tests (erythrocyte sedimentation rate [ESR], C-reactive protein [CRP], and D-dimer), singly and in combination?
Methods: Between March 2016 and March 2020, 94 patients undergoing revision total shoulder arthroplasty (anatomic or reverse) at a single institution had preoperative serum testing with CRP, ESR, and D-dimer. Read More