Prev Vet Med 2021 Jul 14;194:105433. Epub 2021 Jul 14.
The University of Queensland, School of Veterinary Science, Gatton, Queensland, 4343, Australia; The University of Queensland, Good Clinical Practice Research Group (GCPRG), Gatton, Queensland, 4343, Australia; Murdoch University, School of Veterinary Medicine, Perth, Western Australia, 6150, Australia. Electronic address:
The aim of this study was to appraise the available evidence on the effectiveness of probiotic treatment on mature cattle immunity, inflammation, and disease prevention. A systematic review with meta-analysis was conducted to analyse studies that were eligible to answer the following research question: "in cattle of at least 6-months of age, is the use of probiotics associated with immunomodulatory and inflammatory responses, and clinical disease outcomes?" Our literature search yielded 25 studies that fit the inclusion criteria. From these studies, only 19 were suitable for inclusion in the meta-analysis due to data limitations and differences in study population characteristics. Read More