42,267 results match your criteria septal defect

Predictors of New-Onset Atrial Tachyarrhythmias After Transcatheter Atrial Septal Defect Closure in Adults.

Heart Lung Circ 2021 Apr 13. Epub 2021 Apr 13.

Department of Cardiology, Keio University School of Medicine, Tokyo, Japan. Electronic address:

Background: New-onset atrial tachyarrhythmia (ATA) often develops after atrial septal defect (ASD) closure. Its development raises some potential concerns such as stroke and bleeding complications caused by anticoagulant therapy and limited access to the left atrium for catheter ablation. Although it is essential to identify the risk factors of new-onset ATA, few studies have examined these factors. Read More

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Deployed Dimensions of the GORE® CARDIOFORM ASD Occluder as Function of Defect Size.

Pediatr Cardiol 2021 Apr 16. Epub 2021 Apr 16.

Division of Cardiology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave, Box 21, Chicago, IL, 60611, USA.

The GORE® CARDIOFORM ASD occluder (ASDO) is approved for closure of ASDs up to 35 mm diameter. With an adaptable central waist, each device size is suitable over a range of defect diameters. Understanding deployed dimensions across various defect sizes will assist operators. Read More

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Repair technique for a rare partial anomalous pulmonary venous return associated with retroaortic innominate vein.

J Cardiothorac Surg 2021 Apr 15;16(1):83. Epub 2021 Apr 15.

Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, 41944, 130 Dongdeok-ro, Jung-gu, Daegu, Republic of Korea.

Background: Retroaortic innominate vein (RIV) is a rare vascular abnormality. Although RIV itself is asymptomatic, its presence in patients with partial anomalous pulmonary venous return (PAPVR) to the superior vena cava (SVC) is surgically challenging because a simple Warden procedure is impossible.

Case Presentation: A 16-year-old girl was diagnosed with tetralogy of Fallot, secundum, and sinus venosus atrial septal defect (ASD) at birth. Read More

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An anatomical composite nasal lining subunit technique in primary cleft nose correction.

Derek A Mendonca

JPRAS Open 2021 Jun 6;28:72-76. Epub 2021 Mar 6.

Adjunct Clinical Associate Professor, Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, United Arab Emirates.

Current primary cleft nose correction techniques are associated with a significant rate of long term alar collapse. The nasal lining on the cleft side has been observed to be distorted and deficient. Nasal endoscopy was used to map the two dimensional topography of the anterior nasal airway lining in a normal and patient with unilateral cleft lip. Read More

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Wide QRS complex tachycardia after surgical repair of an isolated atrial septal defect: What is the mechanism?

Norman C Wang

J Arrhythm 2021 Apr 22;37(2):464-466. Epub 2021 Feb 22.

Division of Cardiology Department of Medicine University of Pittsburgh School of Medicine Pittsburgh PA USA.

Macroreentrant atrial tachycardia within the right atrium is the dominant mechanism in patients with prior surgical repair of atrial septal defects, with dual-loop circuits much more common than single-loop circuits. This case highlights the importance of clinical history for predicting arrhythmia mechanisms. Considering prior cardiac surgery may assist in preprocedural preparations and discussions regarding potential risks and benefits of catheter ablation. Read More

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Early single-stage surgical revascularization of pulmonary artery in unilateral absence of a pulmonary artery.

J Cardiothorac Surg 2021 Apr 13;16(1):80. Epub 2021 Apr 13.

Heart Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 9# Jinsui Road, Guangzhou, 510623, China.

Background: This research aims to summarize the findings of the early single-stage revascularization of remnant pulmonary artery in unilateral absent intrapericardial pulmonary artery.

Methods: We retrospectively analyzed the medical records of 10 patients with unilateral absent pulmonary artery, in which 7 were right and 3 were left, the median age and mean weight at surgery was 4 months and 5.6 kg, respectively. Read More

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Higher preoperative Qp/Qs ratio is associated with lower preoperative regional cerebral oxygen saturation in children with ventricular septal defect.

J Anesth 2021 Apr 13. Epub 2021 Apr 13.

Department of Anesthesiology and Resuscitology, Okayama University Hospital, 2-5-1 Shikata-cho, Kitaku, Okayama, 700-8558, Japan.

Purpose: The relationship between regional cerebral oxygen saturation (rSO) and the amount of left-to-right shunt in ventricular septal defect (VSD) patients has not yet been investigated. The purpose of this study was to identify the association of preoperative pulmonary to systemic blood flow (Qp/Qs) ratio and preoperative rSO in patients with VSD.

Methods: We retrospectively evaluated 49 VSD surgical closure candidates at a single institution. Read More

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[Transcatheter closure of ventricular septal defect: how and when?]

G Ital Cardiol (Rome) 2021 Mar;22(3):43-45

U.O.C. Cardiologia, Dipartimento Cardiovascolare - AUSL Romagna, Ospedale Santa Maria delle Croci, Ravenna.

Ventricular septal defect (VSD) is a rare but clinically severe complication of acute myocardial infarction. Although cardiac surgery is the gold standard to correct post-infarction VSD, transcatheter closure represents an effective therapeutic alternative in selected cases. However, the correct timing for VSD correction is a matter of debate. Read More

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The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling.

Cell Death Dis 2021 Apr 12;12(4):393. Epub 2021 Apr 12.

Department of Pediatric Cardiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 200092, Shanghai, China.

Cardiac septum malformations account for the largest proportion in congenital heart defects. The transcription factor Sox7 has critical functions in the vascular development and angiogenesis. It is unclear whether Sox7 also contributes to cardiac septation development. Read More

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Gut lumen formation defect can cause intestinal atresia: evidence from histological studies of human embryos and intestinal atresia septum.

J Dev Orig Health Dis 2021 Apr 12:1-7. Epub 2021 Apr 12.

Department of Anatomy, Wuxi School of Medicine, Jiangnan University, WuXi, Jiangsu214122, China.

Intestinal atresia (IA), a common cause of neonatal intestinal obstruction, is a developmental defect, which disrupts the luminal continuity of the intestine. Here, we investigated (i) the process of lumen formation in human embryos; and (ii) how a defective lumen formation led to IA. We performed histological and histochemical study on 6-10 gestation week human embryos and on IA septal regions. Read More

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Long-term neurodevelopmental effects of intraoperative blood pressure during surgical closure of a septal defect in infancy or early childhood.

Cardiol Young 2021 Apr 12:1-7. Epub 2021 Apr 12.

Department of Anesthesiology, Centre of Head and Orthopaedics, Copenhagen University Hospital, Copenhagen, Denmark.

Background: Many children born with congenital heart defects are faced with cognitive deficits and psychological challenges later in life. The mechanisms behind are suggested to be multifactorial and are explained as an interplay between innate and modifiable risk factors. The aim was to assess whether there is a relationship between mean arterial pressure during surgery of a septal defect in infancy or early childhood and intelligence quotient scores in adulthood. Read More

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A rare combination of pulmonary atresia with ventricular septal defect and congenital aortic stenosis with rheumatic mitral disease in an adolescent.

J Echocardiogr 2021 Apr 11. Epub 2021 Apr 11.

Department of Cardiology, Vardhman Mahavir Medical College and Safdarjung Hospital, 7th floor, Super Speciality Block, New Delhi, 110029, India.

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Validity of congenital malformation diagnoses in healthcare claims from a university hospital in Japan.

Pharmacoepidemiol Drug Saf 2021 Apr 9. Epub 2021 Apr 9.

Laboratory of Clinical Pharmacy, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Miyagi, Japan.

Purpose: This study aimed to assess the validity of diagnoses of congenital malformations (CMs) recorded in claims of a university hospital in Japan.

Methods: Congenital malformations were identified according to Code Q00-Q89 of the International Classification of Diseases, 10th revision. All the children who had been diagnosed with CMs based on their claims in 2015 and within 1 year from their birth month were selected for this study. Read More

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Telemedicine usage via WeChat for Children with Congenital Heart Disease Preoperatively During COVID-19 Pandemic: A Retrospective Analysis.

Int J Qual Health Care 2021 Apr 9. Epub 2021 Apr 9.

Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Background: During the COVID-19 pandemic, parents of infants having medical problem face challenges of insufficient medical resources at home. The purpose of this study was to investigate the effect of WeChat-based telehealth services on the preoperative follow-up of infants with congenital heart disease (CHD) during the COVID-19 pandemic.

Methods: This study retrospectively analyzed the medical records of 190 infants with CHD who underwent remote follow-up via WeChat from December 2019 to May 2020 in Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University. Read More

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[Application of three-staged paramedian forehead flap in reconstruction and repair of full-thickness nasal defect].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;56(4):374-380

Department of Maxillofacial Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

To evaluate the application of three-staged paramendian forehead flap technique in reconstruction of severe full-thickness nasal defect. Clinical data of 7 cases with nasal reconstruction by three-staged forehead flap technique in the First Affiliated Hospital of Xinjiang Medical University and HongKong University Shenzhen Hospital between June 2016 and October 2019 was retrospectively reviewed. All were males aged from 10 to 71 years. Read More

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The complete spectrum of pentalogy of Cantrell in one of a set of dizygotic twins: A case report of a rare congenital anomaly.

Medicine (Baltimore) 2021 Apr;100(14):e25470

College of Medicine.

Rationale: Pentalogy of Cantrell (POC) is an extremely rare syndrome with an estimated incidence of 1:65,000 to 200,000 live births. Its complete form includes a midline epigastric abdominal wall defect, defects affecting the lower sternum, anterior diaphragm, diaphragmatic pericardium, and various intracardiac defects.

Patient Concerns: We report a case of complete POC affecting only the first-born of a set of premature dizygotic twins. Read More

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De Novo mutation of FOXF1 causes alveolar capillary dysplasia with misalignment of pulmonary veins: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25375

Department of Cardiology, Kunming Children's Hospital, Kunming, Yunnan.

Rationale: Alveolar capillary dysplasia with misalignment of the pulmonary veins (ACD/MPV) is a rare congenital malformation in neonates that results in severe respiratory distress and pulmonary hypertension. ACD/MPV is caused by mutations in the FOXF1 gene. Herein, a new case of a girl with ACD/MPV carrying a novel pathogenic variant of FOXF1 was reported. Read More

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Structural Heart Issues in Dextrocardia: Situs Type Matters.

Ochsner J 2021 ;21(1):111-114

Department of Anesthesiology, Louisiana State University Health-Shreveport, Shreveport, LA.

Patients who are diagnosed with dextrocardia, a rare congenital heart condition in which the heart points toward the right side of the chest, need their specific situs classification (eg, solitus, inversus, ambiguus) ascertained to optimize their care and outcomes. In this report, we discuss the perioperative anesthetic management of a patient presenting with dextrocardia. A 44-year-old African American female with a history of hypertension, hyperlipidemia, gastroesophageal reflux disease, and diabetes mellitus type 2 was admitted for shortness of breath, dyspnea on exertion, orthopnea, and paroxysmal nocturnal dyspnea. Read More

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January 2021

Temperate approach to ASD closure in pulmonary arterial hypertension: the fenestrated patch technique.

Cardiol Young 2021 Apr 8:1-5. Epub 2021 Apr 8.

Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey.

The most common CHD in the adult patient population is an atrial septal defect due to its asymptomatic nature in early life. However, when diagnosis and treatment are delayed, pulmonary arterial hypertension may develop as a long-term complication, sometimes before adulthood. The presence of PAH adversely affects the results of surgical treatment and may even eliminate the feasibility of surgery in some patients. Read More

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Secundum atrial septal defects transcatheter closure versus surgery in adulthood: a 2000-2020 systematic review and meta-analysis of intrahospital outcomes.

Cardiol Young 2021 Apr 8:1-6. Epub 2021 Apr 8.

Center of Vascular Excellence, West Virginia University Medical School, Charlstone, WV, USA.

Introduction: Technologically, advances in both transcatheter and surgical techniques have been continuing in the past 20 years, but an updated comprehensive comparison in device-based versus surgery in adults in terms of incidence of in-hospital mortality, perioperative stroke, and atrial fibrillation onset is still lacking. We investigate the performance of transcatheter device-based closure compared to surgical techniques by a systematic review and meta-analysis of the last 20 years literature data.

Material And Methods: The analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Read More

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The road less travelled: percutaneous closure of a secundum atrial septal defect through the left internal jugular vein.

Cardiol Young 2021 Apr 8:1-2. Epub 2021 Apr 8.

Division of Pediatric Cardiology, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA.

In cases where femoral access is untenable for secundum atrial septal defect closure, the internal jugular vein can be used instead. We report a case of atrial septal defect closure in a patient with significant vascular thrombosis, requiring the use of the left internal jugular vein for access. To the best of our knowledge, this is the first report that documents the use of the left internal jugular vein for atrial septal defect closure in a patient with situs solitus anatomy. Read More

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Effect of aortic arch surgery in newborns' cerebral and gastrointestinal hemodynamics: evaluation by Doppler ultrasonography.

J Matern Fetal Neonatal Med 2021 Apr 7:1-7. Epub 2021 Apr 7.

Department of Pediatric Cardiology, Istanbul Saglik Bilimleri University Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital, Istanbul, Turkey.

Aim: In this study, we investigated changes in newborns' cerebral and intestinal blood flow who had undergone aortic arch surgery.

Method: This study was carried out prospectively as a preliminary study in patients younger than 30 days at the time of aortic arch reconstruction between 1 August and 1 December, 2019. Cerebral and gastrointestinal hemodynamics were evaluated with Doppler USG before and 7 days after the operation. Read More

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Thirteen dogs and a cat with ultrasonographically detected gallbladder wall edema associated with cardiac disease.

J Vet Intern Med 2021 Apr 7. Epub 2021 Apr 7.

Oncura Partners Diagnostics, Fort Worth, Texas, USA.

Background: Ultrasonographically detected gallbladder wall edema (GBWE) is a marker for anaphylaxis in dogs. Cardiac disease can cause GBWE with similar signs and should be included as a differential diagnosis to prevent interpretation errors.

Hypothesis/objectives: Document GBWE associated with cardiac disease. Read More

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Right ventricular ischemia by myocardial perfusion imaging in a 6-year-old child with pulmonary hypertension after ventricular septal defect repair.

J Nucl Cardiol 2021 Apr 6. Epub 2021 Apr 6.

Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

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Safety and Efficacy of Transcatheter Occlusion of Perimembranous Ventricular Septal Defect with Aortic Valve Prolapse: A Six-Year Follow-Up Study.

J Interv Cardiol 2021 18;2021:6634667. Epub 2021 Mar 18.

Graduate School, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

Background: With the rapid development of transcatheter techniques and instruments, transcatheter occlusion for patients with perimembranous ventricular septal defect (pVSD) and aortic valve prolapse (AVP) was constantly being tried, while the efficacy and safety of pVSD with AVP remain controversial.

Objective: The aim of this study was to evaluate long-term efficacy and safety of transcatheter occlusion of pVSD with AVP.

Methods: We retrospectively analyzed 164 children with pVSD and AVP who underwent transcatheter occlusion between January 2013 and November 2014. Read More

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Cardiac Anomalies in Two White-Tailed Eagles (Haliaeetus albicilla) in Sweden.

J Wildl Dis 2021 Apr;57(2):413-417

Department of Pathology and Wildlife Diseases, National Veterinary Institute, 751 89, Uppsala Sweden.

Severe cardiomegaly with an atrial septal defect was discovered during necropsy of a subadult White-tailed Eagle (Haliaeetus albicilla) found dead in the wild. A thin membrane composed of fibromuscular tissue separated the left atrium into two chambers, most consistent with that described for cor triatriatum sinister (CTS) in other species. Seventeen months later, necropsy of an adult White-tailed Eagle again revealed CTS. Read More

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A contemporary review of "realistic" success rates after surgical closure of nasal septal perforations.

Auris Nasus Larynx 2021 Apr 2. Epub 2021 Apr 2.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Ulm, Germany.

Objective: The surgical closure of septal perforations is a challenging procedure. Various techniques exist. Each perforation proves that there is not the one precise procedure for all perforations. Read More

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Case report of a novel phenotype in 18q deletion syndrome.

Rom J Morphol Embryol 2020 Jul-Sep;61(3):905-910

Department of Anatomy, Department of Pathology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;

The latest decades are characterized by an enormous progression in the field of human genetics. In consequences, for various phenotypic manifestations, genetic testing could identify a specific underlying cause. An estimated incidence for all types of 18q deletions is one in 55 000 births predominant on females. Read More

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Percutaneous closure of ventricular septal defects in children: key parameters affecting patient radiation exposure.

Am J Cardiovasc Dis 2021 15;11(1):65-72. Epub 2021 Feb 15.

Bicêtre Hospital, Department of Radiology and Nuclear Medicine, Paris-Sud University Hospitals 94270 Le Kremlin-Bicêtre, Paris, France.

Background: Ventricular septal defect (VSD) transcatheter closure is gaining worldwide popularity despite its complexity. Reports on key factors affecting radiation exposure in children are scarce.

Aims: This clinical study is the first to comprehensively analyze the impact of all relevant parameters on children's radiation exposure during VSD interventional closures. Read More

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February 2021