7,119 results match your criteria sensory block


Efficacy and safety of ultrasound-guided above-knee lateral approach for popliteal sciatic nerve block in surgeries below the knee: a randomized controlled trial.

Ann Palliat Med 2021 May 10. Epub 2021 May 10.

Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Background: Ultrasound guidance has become a standard method for detection of nerve structures in regional anesthesia. During ultrasound-guided blockade, to identify anatomical structures is crucial but can be challenging. In clinical practice, we find a wide difference in the visibility score of the sciatic nerve (SN) through different approaches. Read More

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A randomised, non-inferiority study of chloroprocaine 2% and ropivacaine 0.75% in ultrasound-guided axillary block.

Sci Rep 2021 May 11;11(1):10035. Epub 2021 May 11.

Department of Anaesthesia, General Intensive Care Medicine and Pain Therapy, Medical University of Vienna, Vienna, Austria.

Chloroprocaine is a short-acting local anaesthetic with a rapid onset of action and an anaesthesia duration up to 60 min. In this pivotal study success rates, onset and remission of motor and sensory block and safety of chloroprocaine 2% was compared to ropivacaine 0.75% for short-duration distal upper limb surgery with successful block rates as primary outcome. Read More

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Efficacy of perineural versus intravenous dexmedetomidine as a peripheral nerve block adjunct: a systematic review.

Reg Anesth Pain Med 2021 May 11. Epub 2021 May 11.

Anesthesia, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada

Background: Dexmedetomidine is an effective local anesthetic adjunct for peripheral nerve blocks. The intravenous route for administering dexmedetomidine has been suggested to be equally effective to the perineural route; but comparative evidence is conflicting.

Objectives: This evidence-based review evaluated trials comparing the effects of intravenous to perineural dexmedetomidine on peripheral nerve block characteristics in adult surgical patients. Read More

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Percutaneous Cryoneurolysis for Acute Pain Management: Current Status and Future Prospects.

Expert Rev Med Devices 2021 May 7. Epub 2021 May 7.

University of California San Diego, Department of Anesthesiology, San Diego, California.

Introduction: Conventional nerve blocks utilize local anesthetic drugs to provide pain relief for hours or days following surgery or trauma. However, postoperative and trauma pain can last weeks or months. Ultrasound-guided percutaneous cryoneurolysis is an anesthetic modality that offers substantially longer pain relief compared to local anesthetic-based nerve blocks. Read More

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Suppression of neuropathic pain and comorbidities by recurrent cycles of repetitive transcranial direct current motor cortex stimulation in mice.

Sci Rep 2021 May 6;11(1):9735. Epub 2021 May 6.

Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Im Neuenheimer Feld 366, 69120, Heidelberg, Germany.

Transcranial, minimally-invasive stimulation of the primary motor cortex (M1) has recently emerged to show promise in treating clinically refractory neuropathic pain. However, there is a major need for improving efficacy, reducing variability and understanding mechanisms. Rodent models hold promise in helping to overcome these obstacles. Read More

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Characterization of putative transcriptional regulator (PH0140) and its distal homologue.

Cell Signal 2021 Apr 29;84:110031. Epub 2021 Apr 29.

Structural Biology and Bio-Computing Lab, Department of Bioinformatics, Science Block, Alagappa University, Karaikudi 630 004, India. Electronic address:

In this study, a phylogenetic tree was constructed using 1854 sequences of various Lrp/AnsC (FFRPs) and ArsR proteins from pathogenic and non-pathogenic organisms. Despite having sequence similarities, FFRPs and ArsR proteins functioning differently as a transcriptional regulator and de-repressor in the presence of exogenous amino acids and metal ions, respectively. To understand these functional differences, the structures of various FFRPs and ArsR proteins (134 sequences) were modeled. Read More

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Dexmedetomidine versus sufentanil as adjuvants to bupivacaine for brachial plexus block during upper extremity surgery: a randomized clinical trial.

Braz J Anesthesiol 2021 Apr 28. Epub 2021 Apr 28.

AJA University of Medical Sciences, Department of Anesthesiology, Tehran, Iran. Electronic address:

Background: Brachial plexus block (BPB) has been accepted as a reliable alternative for general anesthesia in upper limb surgeries. Adding adjuvant drugs like dexmedetomidine and sufentanil has been shown to have clinical and pharmacologic advantages. In this randomized parallel clinical trial, we aim to compare the effects of these two adjuvants for bupivacaine in BPB. Read More

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The Effect of Dexmedetomidine in Combination with Bupivacaine on Sensory and Motor Block Time and Pain Score in Supraclavicular Block.

Pain Res Manag 2021 10;2021:8858312. Epub 2021 Apr 10.

Department of Anesthesiology, Urmia Imam Khomeini Hospital, Urmia University of Medical Science, Urmia, Iran.

Background: Brachial plexus block is frequently recommended for upper limb surgeries. Many drugs have been used as adjuvants to prolong the duration of the block. This study aimed to assess the effect of dexmedetomidine with bupivacaine combination and only bupivacaine on sensory and motor block duration time, pain score, and hemodynamic variations in the supraclavicular block in upper extremity orthopedic surgery. Read More

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Vincristine-Induced Peripheral Neuropathy (VIPN) in Pediatric Tumors: Mechanisms, Risk Factors, Strategies of Prevention and Treatment.

Int J Mol Sci 2021 Apr 16;22(8). Epub 2021 Apr 16.

Pediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.

Vincristine-induced peripheral neurotoxicity (VIPN) is a very common side effect of vincristine chemotherapy among pediatric patients with cancer. Neuropathy may be sensory, motor and/or autonomic, with consequent reduction, delay or discontinuation of vincristine-chemotherapy, but also pain, disability, reduced quality of life of patients and an increase in medical costs. Vincristine acts out its antineoplastic function by altering the normal assembly and disassembly of microtubules, with their consequent mitosis block and death. Read More

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Effect of Serving Plate Types and Color Cues on Liking and Purchase Intent of Cheese-Flavored Tortilla Chips.

Foods 2021 Apr 17;10(4). Epub 2021 Apr 17.

School of Nutrition and Food Sciences, Louisiana State University Agricultural Center, Baton Rouge, LA 70803, USA.

Foods' overall liking (OL) and purchase intent (PI) are influenced by visual inputs, such as color cues and serving plate types. Cheese-flavored tortilla chips (CFTC) from two formulations (A and B) with a noticeable color difference (∆E = 4.81) were placed on different serving plates (plastic, foam, and paper) and presented monadically to N = 83 consumers using a randomized/balanced block design in two sessions. Read More

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Lateral Sagittal Versus Costoclavicular Approaches for Ultrasound-Guided Infraclavicular Brachial Plexus Block: A Comparison of Block Dynamics Through A Randomized Clinical Trial.

Cureus 2021 Mar 26;13(3):e14129. Epub 2021 Mar 26.

Anesthesiology and Reanimation, Ondokuz Mayis University, Samsun, TUR.

Introduction In this study, our objective was to compare the lateral sagittal infraclavicular block (LS-ICB) with the costoclavicular infraclavicular block (CC-ICB) for ultrasound (US)-guided infraclavicular brachial plexus block in terms of block dynamics as well as patient and surgeon satisfaction levels. Methods A total of 100 patients, falling under the American Society of Anaesthesiologists (ASA) I-III categories, who were aged 18-65 years and scheduled for elective forearm and hand surgery were enrolled in the study. The patients were randomly allocated to receive a US-guided LS-ICB or US‑guided CC-ICB. Read More

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Sensory block level prediction of spinal anaesthesia with 0.5% hyperbaric bupivacaine: a retrospective study.

Sci Rep 2021 Apr 27;11(1):9105. Epub 2021 Apr 27.

Department of Anesthesiology, Taipei Veterans General Hospital, Taipei, Taiwan.

There is still no consensus on how to determine the dose of spinal anaesthesia with adequate sensory block for a planned surgery. This retrospective study aimed to explore the associations of miscellaneous factors with peak sensory block level after spinal anaesthesia with hyperbaric bupivacaine, and to construct a predictive model for single-shot spinal anaesthesia. We collected the records of 401 non-pregnant adults who underwent spinal anaesthesia with 0. Read More

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Effects of tactile stimulation on the sensory, motor and cognitive function in people with multiple sclerosis.

Clin Neurol Neurosurg 2021 Apr 20;205:106643. Epub 2021 Apr 20.

Physiology-pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Electronic address:

Objective: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease that causes demyelination in the brain and spinal cord. Repetitive sensory stimulation (RSS) can enhance sensory perception and motor function, improve inappropriate synaptic connections and adaptable malformations, and increase cognitive function. The purpose of this study was to specify the effect of RSS on the sensory, motor, and cognitive function in people with MS. Read More

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Effect of combined versus sequential injection of 2% lidocaine and 0.5% bupivacaine on the onset and duration of supraclavicular brachial plexus block: A double blinded randomised controlled trial.

J Clin Anesth 2021 Apr 24;72:110313. Epub 2021 Apr 24.

Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, India.

Objective: To assess whether sequential (one after the other with a delay of 120 s) or combined (freshly prepared mixture) administration of 2% lidocaine and 0.5% bupivacaine in supraclavicular brachial plexus block (SCBPB) provides faster onset and prolonged duration of block.

Design: Randomised controlled double blinded study. Read More

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Spinal subdural hematoma and subdural anesthesia following combined spinal-epidural anesthesia: a case report.

BMC Anesthesiol 2021 Apr 26;21(1):130. Epub 2021 Apr 26.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Sichuan Province, Chengdu, China.

Background: Subdural anesthesia and spinal subdural hematoma are rare complications of combined spinal-epidural anesthesia. We present a patient who developed both after multiple attempts to achieve combined spinal-epidural anesthesia.

Case Presentation: A 21-year-old parturient, gravida 1, para 1, with twin pregnancy at gestational age 34 weeks underwent cesarean delivery. Read More

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ELECTROPHYSIOLOGICAL STUDY OF THE TIBIAL NERVE ACROSS THE TARSAL TUNNEL IN DISTAL SYMMETRIC DIABETIC POLYNEUROPATHY.

Am J Phys Med Rehabil 2021 Apr 14. Epub 2021 Apr 14.

EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy.

Objective: To demonstrate abnormalities of motor conduction of the tibial nerve across the tarsal tunnel (TT) in type 2 diabetes.

Design: 124 consecutive patients (mean age 66.6 years, 62. Read More

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Assessment of main complications of regional anesthesia recorded in an acute pain unit in a tertiary care university hospital: a retrospective cohort.

Braz J Anesthesiol 2021 Apr 19. Epub 2021 Apr 19.

Hospital Universitário São João, Departamento de Anestesiologia, Porto, Portugal.

Background: Regional anesthesia has been increasingly used. Despite its low number of complications, they are associated with relevant morbidity. This study aims to evaluate the incidence of complications after neuraxial block and peripheral nerve block. Read More

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Nalbuphine for spinal anesthesia : A Systematic Review and meta-analysis.

Pain Pract 2021 Apr 22. Epub 2021 Apr 22.

Department of Anesthesiology, Huai'an Hospital, Xuzhou Medical University, Jiangsu Province, Huai'an, 223002, China.

Purpose: Various adjuvants for prolongation of intraoperative and postoperative analgesia have been clinically studied, but the safety and efficiency of nalbuphine as an adjuvant to local anesthetics in spinal anesthesia remains unconfirmed. Therefore, we conducted a meta-analysis about the effect of nalbuphine as an adjuvant to local anesthetics in spinal anesthesia in regard to time of onset of sensory blockade and motor blockade,duration of motor blockade, two-segment sensory regression time, the duration of analgesia, and incidence of side effects to provide a reliable basis for clinical application.

Methods: Databases including PubMed, Cochrane, EMBASE, Web of Science, CNKI, CBM, WanFang database and Viper database were searched for eligible studies. Read More

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Prospective Randomized Control Trial Comparing Effect of Dexamethasone Versus Fentanyl as Adjuvants to Intrathecal Bupivacaine for Orthopedic Surgery.

Cureus 2021 Mar 17;13(3):e13949. Epub 2021 Mar 17.

Orthopedics, Medanta Hospital, Gurgaon, IND.

Introduction Spinal anesthesia is the most consistent block for lower limb orthopedic surgeries. We conducted this randomized prospective study to evaluate comparative efficacy of intrathecal dexamethasone with fentanyl and normal saline as adjuvants to hyperbaric bupivacaine in spinal anesthesia administered to patients scheduled for lower limb orthopedic surgery. Materials and methods 105 patients scheduled for lower limb orthopedic surgeries under spinal anesthesia were included in this clinical trial. Read More

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A Modified Approach Below the Lateral Arcuate Ligament to Facilitate the Subcostal Anterior Quadratus Lumborum Block.

J Pain Res 2021 13;14:961-967. Epub 2021 Apr 13.

Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, People's Republic of China.

Purpose: The subcostal quadratus lumborum (QL) block was used in postoperative analgesia for abdominal surgery. However, it is difficult to precisely put the needle tip into the target fascia compartment. In the current study, we proposed a modified approach to facilitate the subcostal QL block. Read More

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Integrated H NMR fingerprint with NIR spectroscopy, sensory properties, and quality parameters in a multi-block data analysis using ComDim to evaluate coffee blends.

Food Chem 2021 Sep 19;355:129618. Epub 2021 Mar 19.

Universidade Tecnológica Federal do Paraná, Campus Campo Mourão (UTFPR-CM), Campo Mourão, Paraná, Brazil. Electronic address:

Coffee quality is determined by several factors and, in the chemometric domain, the multi-block data analysis methods are valuable to study multiple information describing the same samples. In this industrial study, the Common Dimension (ComDim) multi-block method was applied to evaluate metabolite fingerprints, near-infrared spectra, sensory properties, and quality parameters of coffee blends of different cup and roasting profiles and to search relationships between these multiple data blocks. Data fusion-based Principal Component Analysis was not effective in exploiting multiple data blocks like ComDim. Read More

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September 2021

CaDIS: Cataract dataset for surgical RGB-image segmentation.

Med Image Anal 2021 Mar 31;71:102053. Epub 2021 Mar 31.

Digital Surgery LTD, 230 City Road, London, EC1V 2QY, UK; Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, Gower Street, London, WC1E 6BT, UK.

Video feedback provides a wealth of information about surgical procedures and is the main sensory cue for surgeons. Scene understanding is crucial to computer assisted interventions (CAI) and to post-operative analysis of the surgical procedure. A fundamental building block of such capabilities is the identification and localization of surgical instruments and anatomical structures through semantic segmentation. Read More

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Effect of sensory blockade and rate of sensory stimulation on local heating induced axon reflex response in facial skin.

Auton Neurosci 2021 Apr 7;233:102809. Epub 2021 Apr 7.

Department of Physical Therapy, School of Health & Human Sciences; and (2)Departments of Dermatology and Anatomy, Cell Biology, & Physiology, School of Medicine, Indiana University, Indianapolis, IN, USA. Electronic address:

Local neuronal circuits in non-glabrous skin drive the initial increase of the biphasic cutaneous vasodilation response to fast non-noxious heating. Voltage-sensitive Na (NaV) channel inhibition blocks the afferent limb of the non-glabrous forearm cutaneous axon reflex. Slow local heating does not engage this response. Read More

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Proximate Composition, Antinutritional Content, Microbial Load, and Sensory Acceptability of Noodles Formulated from Moringa () Leaf Powder and Wheat Flour Blend.

Int J Food Sci 2021 31;2021:6689247. Epub 2021 Mar 31.

Center of Food Science and Nutrition, Addis Ababa University, Ethiopia.

Background: Noodle products are popular throughout the world, and they can be prepared from cereal like wheat, maize, and rice. Nowadays, healthy and nutritious product requirement has been increasing. Thus, research on the nutrition-rich but neglected crop is becoming visible nowadays to ensure global food security and to satisfy the nutritional need. Read More

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Influence of Stochastic Resonance on Manual Dexterity in Children With Developmental Coordination Disorder: A Double-Blind Interventional Study.

Front Neurol 2021 30;12:626608. Epub 2021 Mar 30.

Neurorehabilitation Research Center, Kio University , Kitakatsuragi-gun, Japan.

There is increasing evidence that the stochastic resonance (SR) phenomenon provided by subthreshold mechanical noise stimulation improves the sensory-motor system. However, the effect of SR on children with developmental coordination disorder (DCD) is unclear. The purpose of this study was to assess whether SR activated by subthreshold vibrotactile noise stimulation of the wrist influences manual dexterity in children with DCD. Read More

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The Inhibitory Thermal Effects of Focused Ultrasound on an Identified, Single Motoneuron.

eNeuro 2021 Mar-Apr;8(2). Epub 2021 Apr 30.

Graduate Program in Neuroscience, University of Minnesota, St. Paul, MN 55108

Focused ultrasound (US) is an emerging neuromodulation technology that has gained much attention because of its ability to modulate, noninvasively, neuronal activity in a variety of animals, including humans. However, there has been considerable debate about exactly which types of neurons can be influenced and what underlying mechanisms are in play. Are US-evoked motor changes driven indirectly by activated mechanosensory inputs, or more directly via central interneurons or motoneurons? Although it has been shown that US can mechanically depolarize mechanosensory neurons, there are no studies that have yet tested how identified motoneurons respond directly to US and what the underlying mechanism might be. Read More

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Fentanyl and clonidine as adjuncts to a mixture of local anesthetics in potentiating postoperative analgesia in supraclavicular block: A randomized controlled study.

Int J Crit Illn Inj Sci 2020 Oct-Dec;10(4):163-169. Epub 2020 Dec 29.

Deparment of Obstetrics and Gynaecology, Government Medical College, Amritsar, Punjab, India.

Background: Brachial plexus block is popular for upper limb surgeries as it is effective for postoperative analgesia.

Aims: The aim of the study was to compare fentanyl and clonidine as adjuncts to a mixture of local anesthetics in potentiating postoperative analgesia in the supraclavicular block.

Materials And Methods: Sixty patients of the American Society of Anesthesiologist I and II undergoing upper limb surgeries lasting more than 30 min were included and randomly divided into two groups of 30 each. Read More

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December 2020

Comparison of the Ulnar Nerve Blockade between Intertruncal and Corner Pocket Approaches for Supraclavicular Block: A Randomized Controlled Trial.

Korean J Anesthesiol 2021 Apr 12. Epub 2021 Apr 12.

Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital.

Background: The corner pocket (CP) approach for supraclavicular block (SCB) prevents ulnar nerve (UN) sparing due to needle proximity of lower trunk. Improved ultrasound resolution has suggested that the intertruncal (IT) approach is a suitable alternative method. However, the comparative efficiency of these two approaches on UN block has not been evaluated. Read More

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[Clinical study of age-related sensory innervation of the anterior hard palate].

Hua Xi Kou Qiang Yi Xue Za Zhi 2021 Apr;39(2):170-174

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Objectives: The present study aimed to explore the innervation of the anterior hard palatine and its relationship with individual development stage. Specifically, the effects of anesthesia on patients of different ages were observed, and neurodevelopment in the maxillofacial region was invesitgated. References that are helpful in selecting local anesthesia were provided. Read More

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Analgesic efficacy of paraspinal interfascial plane blocks performed with the use of neurophysiology monitoring for posterior cervical laminectomy surgery: a case series.

J Spine Surg 2021 Mar;7(1):109-113

Division of Regional Anesthesia & Acute Pain Management, Department of Anesthesiology, Westchester Medical Center/New York Medical College, Valhalla, NY, USA.

Posterior cervical spine surgery often requires large posterior midline incision which can result in poorly controlled postoperative pain, arises from iatrogenic mechanical damage, intraoperative retraction and resection to structures such as bone, ligaments, muscles, intervertebral disks, and zygapophysial joints. Local anesthetics may be utilized for infiltration of the surgical wound; however, their analgesic efficacy has not been studied in this surgical approach. Here we report a case series. Read More

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