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Addressing structural discrimination: prioritising people with mental health and addiction issues during the COVID-19 pandemic.

N Z Med J 2021 Jul 9;134(1538):128-134. Epub 2021 Jul 9.

Professor (Pathology), Department of Pathology and Biomedical Science, University of Otago, Christchurch - Te Whare Wānanga o Otāgo ki Ōtautahi, Christchurch.

Structural discrimination worsens physical health inequities and significantly reduces life expectancy for people with mental health and addiction issues. Aotearoa has recently made some notable changes in health policy by formally recognising the physical health needs of people with mental health and addiction issues. The COVID-19 vaccination sequencing framework provides an important opportunity to protect and promote the health of people with addiction and mental health issues. Read More

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Identifying Predictors of Airway Complications During Conscious Sedation Procedures.

Gastroenterol Nurs 2021 Jul 27. Epub 2021 Jul 27.

Rosemary Bray, DNP, RN, CCRN, CNML, is Senior Director of Nursing, Intensive Care Unit, Gastroenterology Services, Ambulatory Surgery and Nursing Administration, French Hospital Medical Center, San Luis Obispo, California. Herschel Knapp, PhD, MSSW, is Director, Dignity Health Nursing Research Fellowship Program, Southern California Regional Office, Los Angeles.

Conscious sedation procedures are complicated by unanticipated airway compromise and obstruction. The STOP-Bang questionnaire (University of Toronto, 2012) is a validated obstructive sleep apnea screening questionnaire used as a preprocedure evaluation tool to assess a patient's risk for obstructive sleep apnea. The purpose of this study was to determine whether risk factors for obstructive sleep apnea, using the STOP-Bang questionnaire, could predict procedural airway complications in 152 endoscopy patients following conscious sedation. Read More

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CT-Guided Endovascular Exclusion of Pseudoaneurysmal Subclavian Bypass After Early-Age Surgical Correction of Complex Aortic Coarctation.

JACC Case Rep 2021 Feb 3;3(2):225-229. Epub 2021 Feb 3.

DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, USA.

We describe a 64-year-old woman with subclavian pseudoaneurysm after aortic coarctation repair, treated using a hybrid approach involving true three-dimensional analysis and image fusion-guided placement of thoracic endovascular aortic repair stents. This case illustrates the potential complications of coarctation repair and need for lifelong surveillance in these patients. (). Read More

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February 2021

Effect of Endometrial Thickness and duration of Estrogen Supplementation on Fertilization-Intracytoplasmic Sperm Injection Outcomes in Fresh Ovum/Embryo Donation Cycles.

J Hum Reprod Sci 2021 Apr-Jun;14(2):167-174. Epub 2021 Jun 28.

Director, Nova IVF Fertility, Navrangpura, Ahmedabad, Gujarat, India.

Background: There is no consensus regarding optimal endometrial thickness and duration of estrogen supplementation in embryo transfer cycles, at present.

Aims: To observe the effect of endometrial thickness and/or duration of estrogen supplementation on fertilization (IVF)/intracytoplasmic sperm injection (ICSI) outcomes in fresh ovum/embryo donation cycles.

Settings And Design: This was a retrospective observational study. Read More

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Building a Transition Program for Senior Nurse Leaders.

J Nurses Prof Dev 2021 Jul 27. Epub 2021 Jul 27.

Sharon R. Kauffman, PhD, RN, NPD-BC, OCN, is Clinical Coordinator, Allegheny Health Network Cancer Institute, Pittsburgh, Pennsylvania. Julia W. Aucoin, DNS, NPD-BC, CNE, is the Director of Practice, Quality, and Research, UNC REX Healthcare, Raleigh, North Carolina.

Professional development educators undertake a primary role in building organizational transition programs for nurses. Transitions of senior nurse leaders are complex and poorly understood. A Hermeneutic phenomenological study was conducted to investigate the lived experiences of nine novice senior nurse leaders. Read More

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Advance Directives for Adolescents and Young Adults Living With Neuromuscular Disease: An Integrative Review of the Literature.

J Hosp Palliat Nurs 2021 Jul 26. Epub 2021 Jul 26.

Vanessa Battista, DNP, MBA, MS, RN, CPNP-PC, CHPPN, is pediatric nurse practitioner, The Children's Hospital of Philadelphia, PA. Deborah J. Baker, DNP, ACNP, NEA-BC, is senior vice president for Nursing, Vice President for Nursing & Patient Care Services, and Chief Nursing Officer, Johns Hopkins Health System - The Johns Hopkins Hospital, Baltimore, MD; and associate dean for Health Systems Partnership and Innovation, Johns Hopkins University School of Nursing, Baltimore, MD. Tara Trimarchi, DNP, RN, CRNP, is senior director of Care Management, The Children's Hospital of Philadelphia, PA. Bushra Sabri, PhD, MSW, is assistant professor, Johns Hopkins University School of Nursing. Rita F. D'Aoust, PhD, is associate professor and associate dean for Teaching and Learning, Johns Hopkins School of Nursing. Rebecca Wright, PhD, BSc (Hons), RN, is an assistant professor, Johns Hopkins School of Nursing, Baltimore, MD.

The use of advance directives is an important component in helping individuals living with chronic and/or life-threatening illnesses establish goals of care and make decisions regarding care at the end of life. Advance care planning may help achieve enhanced health outcomes, yet it is not routinely offered to adolescents/young adults living with neuromuscular disease. An integrative review of the literature was conducted to examine the evidence related to the use of advance directives with adolescents/young adults living with neuromuscular disease and to identify reasons why they are not being used and how this can be improved. Read More

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Prenatal exposure to particulate matter air pollution: a preventable risk for childhood asthma.

Authors:
David B Peden

J Allergy Clin Immunol 2021 Jul 23. Epub 2021 Jul 23.

Andrews Distinguished Professor of Pediatrics, Division of Pediatric Allergy and Immunology, Senior Associate Dean for Translational Research &, Deputy Director, Center for Environmental Medicine, Asthma and Lung Biology, The School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

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BRIDGING THE GAP BETWEEN PILOT AND SCALE-UP: A MODEL OF ANTENATAL TESTING FOR CURABLE SEXUALLY TRANSMITTED INFECTIONS FROM BOTSWANA.

Sex Transm Dis 2021 Jul 24. Epub 2021 Jul 24.

Assistant Professor, Division of Infectious Diseases and Global Health, Department of Medicine, University of California, San Diego Assistant Professor, Fielding School of Public Health, University of California, Los Angeles, USA Associate Professor, Division of Infectious Diseases and Global Health, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA USA Senior Research Associate, Botswana Harvard Aids Institute Partnership Sexual & Reproductive Health Lead Physician, Botswana UPenn Partnership Professor (Hon), Women's Health Research Unit, Division of Social/Behavioural Sciences, School of Public Health, UCT Clinical Reader in International Sexual and Reproductive Health, Liverpool School of Tropical Medicine Deputy Director, UK Faculty of Sexual and Reproductive Health Care Clinical Effectiveness Unit Deputy Dean of Research and Graduate Studies, Faculty of Medicine, University of Botswana, Acting Dean, School of Medicine, University of Botswana Professor, Fielding School of Public Health, University of California, Los Angeles, USA Professor Emeritus, Luskin School of Public Policy, University of California, Los Angeles, USA.

Introduction: Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are common sexually transmitted infections (STIs) associated with adverse outcomes - yet most countries do not test and conduct syndromic management, which lacks sensitivity and specificity. Innovations allow for expanded STI testing; however, cost is a barrier.

Methods: Using inputs from a pilot program in Botswana, we developed a model among a hypothetical population of 50,000 pregnant women to compare one-year costs and outcomes associated with three antenatal STI testing strategies: 1) point-of-care, 2) centralized laboratory hubs, and 3) a mixed approach (point-of-care at high-volume sites, and hubs elsewhere); and syndromic management. Read More

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Pressure Injury Development, Mitigation, and Outcomes of Patients Proned for Acute Respiratory Distress Syndrome.

Adv Skin Wound Care 2021 Jul 23. Epub 2021 Jul 23.

At Massachusetts General Hospital in Boston, Virginia Capasso, PhD, CNP, ACNS-BC, CWS, FACCWS, is Nurse Scientist, Yvonne L. Munn Center for Nursing Research; Colleen Snydeman, PhD, RN, is Executive Director; Karen Miguel, MM-H, RN, is Staff Specialist; Xianghong Wang, MS, is Senior Analyst; Michelle Crocker, BSN, RN, is Staff Nurse, Cardiac Intensive Care Unit; Zachary Chornoby, BSN, RN, CCRN, is Staff Nurse, Cardiac Intensive Care Unit; Mark Vangel, PhD, is Statistician, Marino Center for Radiology; Mary Ann Walsh, BSN, RN, is Nurse Clinician; John Murphy, DNP, RN, is Staff Specialist, Center for Quality & Safety; and Stephanie Qualls, MSN, RN, is Clinical Nurse Specialist, Neuroscience Intensive Care Unit. Acknowledgment: The authors thank Janet Cuddigan, PhD, RN, FAAN for her critical review of this manuscript. The authors have disclosed no financial relationships related to this article. Submitted February 21, 2021; accepted in revised form March 31, 2021.

Objective: To describe trends and risk factors for pressure injuries (PI) in adult critical care patients placed in prone position between April 9, 2020 and June 8, 2020 to alleviate acute respiratory distress syndrome (ARDS) secondary to COVID-19 and examine effectiveness of products and strategies to mitigate PIs.

Methods: A retrospective chart review was conducted. Demographic data were analyzed using descriptive statistics. Read More

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The role of three-dimensional printed cardiac models in the management of complex congenital heart diseases.

Med J Armed Forces India 2021 Jul 2;77(3):322-330. Epub 2021 May 2.

Professor & Director, Consultant Paediatric Cardiothoracic Surgeon, Fortis-Escorts Heart Institute, Okhla Road, New Delhi, India.

Background: Threedimensional printing is a process enabling computer-assisted conversion of imaging data from patients into physical "printed" replicas. This has been extrapolated to reconstructing patient-specific cardiac models in congenital heart diseases. The aim of this study was to analyze the impact of threedimensional printing in surgical decision making in selected cases of complex congenital heart disease by creating patient-specific printed models. Read More

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Catheter ablation of complex cardiac arrhythmias: Single-centre experience in Armed Forces.

Med J Armed Forces India 2021 Jul 24;77(3):312-321. Epub 2021 Mar 24.

Director General Armed Forces Medical Services & Senior Colonel Commandant, O/o DGAFMS, MOD, 'M' Block, New Delhi, India.

Background: Complex arrhythmia ablation remains a technical challenge despite advances in hardware and mapping techniques. The aim of the study was to analyse the efficacy of radiofrequency ablation of arrhythmias requiring complex electrophysiological procedures at a tertiary-care centre.

Methods: A retrospective study was done for catheter ablation of arrhythmias performed at a single centre from Aug 2012 to Nov 2016 (4 years 4 months). Read More

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Safety Assessment of Peel-Derived Ingredients as Used in Cosmetics.

Int J Toxicol 2021 Jul 26:10915818211032617. Epub 2021 Jul 26.

Cosmetic Ingredient Review Executive Director.

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 47 peel-derived ingredients, which are most frequently reported to function in cosmetics as skin conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanical ingredients, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. Read More

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HEALTHCARE WORKERS NEED COVID-19 VACCINATION: CLINICAL, PUBLIC HEALTH AND ETHICAL CONSIDERATIONS.

Am J Med 2021 Jul 20. Epub 2021 Jul 20.

First Sir Richard Doll Professor & Senior Academic Advisor to the Dean, Charles E. Schmidt College of Medicine, Florida Atlantic University, 2800 S. Ocean Blvd. PHA, Boca Raton, FL 33432. Electronic address:

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The Role of a Resilient Information Infrastructure in COVID-19 Vaccine Uptake in Ontario.

Healthc Q 2021 Jul;24(2):7-11

A senior scientist and chief science officer at ICES, a clinician scientist at The Hospital for Sick Children and professor of Paediatrics, Health Policy and Public Health at the Dalla Lana School of Public Health at the University of Toronto in Toronto, ON.

The COVID-19 pandemic has highlighted the need for a robust and nimble public health data infrastructure. ICES - a government-sponsored, independent, non-profit research institute in Ontario, Canada - functions as a key component of a resilient information infrastructure and an enabler of data co-production, contributing to Ontario's response to the COVID-19 pandemic as part of a learning health system. Linked data on the cumulative incidence of infection and vaccination at the neighbourhood level revealed disparate uptake between areas with low versus high risk of COVID-19. Read More

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Clinicians' and nurses' documentation practices in palliative and hospice care.

Int J Palliat Nurs 2021 Jul;27(5):227-234

Professor; Consultant Palliative Care Advocate and Physician; Founder Hospice Africa; Director of Policy Hospice Africa, Uganda.

Background: Health workers are likely to document patients' care inaccurately, especially when using new and revised case tools, and this could negatively impact patient care.

Aim: To assess nurses' and clinicians' documentation practices when using a new patients' continuation case sheet (PCCS) and explore nurses' and clinicians' experiences regarding the documentation of patients' information in the new PCCS. The purpose of introducing the PCCS was to improve the continuity of care for patients attending clinics at which they were unlikely to consistently see the same clinician or nurse. Read More

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Conceptualizing Medical Resident's Journey through Wonderland of Clinical Practice: From transitional shock to role adaptation to independent practice.

Pak J Med Sci 2021 Jul-Aug;37(4):1048-1053

Dr. Rahila Yasmeen, BDS, DCPS- HPE, MHPE, PhD-HPE (Scholar). Professor/ Director, Department of Medical Education, DEAN RARE/ ORIC, Riphah International University, Islamabad, Pakistan.

Objectives: To explore experiences of medical residents about stages and nature of transitional journey from induction into residency program to achievement of consultant title.

Methods: Qualitative phenomenological study was conducted at Sir Gangaram hospital and Fatima Memorial Hospital, Lahore for six months from Feb 2019-July 2019 after IRB/ERC approval from Islamic International Medical College (Ref# Riphah/IIMC/ERC/19/0320). Using purposive criterion sampling, 16 semi-structured interviews in four departments, four strata of junior residents, senior residents, newly-qualified consultants, and supervising consultants with four participants each were conducted till theoretical saturation of data was achieved. Read More

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November 2020

Primary care mental health services in Qatar.

BJPsych Int 2021 Feb;18(1):15-18

Senior Consultant Psychiatrist, Chairman, Mental Health Services, Hamad Medical Corporation and Qatar University, Doha, Qatar.

With rapid growth and development in recent decades, the State of Qatar has been redefining strategies and policies towards building a world-class healthcare system. Mental health has emerged as a priority area for development. As a result, mental health services in the region are being redefined and expanded, and this was realised with the launching of the ambitious National Mental Health Strategy in 2013. Read More

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February 2021

Evolving an ethical framework for Covid-19 management in India.

Indian J Med Ethics 2021 Jul-Sep;VI(3):1-20

Director, Professor and Dean, Department of Community Medicine, Maulana Azad Medical College, Delhi, INDIA.

The Covid-19 pandemic has caused millions of cases and deaths worldwide and has caused a massive global economic contraction. Governments, policymakers, and medical professionals have been confronted with several complex bioethical dilemmas during these exceptional circumstances. In developing countries like India, having a large population base, inadequate preexisting public health infrastructure, and a multi-level government system with complex administrative mechanisms imposes enormous barriers and challenges in the effective and ethical management of the pandemic. Read More

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Exploring data management content in doctoral nursing handbooks.

J Med Libr Assoc 2021 Apr;109(2):248-257

Clinical Assistant Professor, Department of Women, Children, and Family Health Science, University of Illinois-Chicago College of Nursing, Director of Nursing Research, University of Illinois Hospital & Health Sciences System, Chicago, IL.

Objective: While data management (DM) is an increasing responsibility of doctorally prepared nurses, little is understood about how DM education and expectations are reflected within student handbooks. The purpose of this study was to assess the inclusion of DM content within doctoral nursing student handbooks.

Methods: A list of 346 doctoral programs was obtained from the American Association of Colleges of Nursing (AACN). Read More

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PRISMA-S: an extension to the PRISMA statement for reporting literature searches in systematic reviews.

J Med Libr Assoc 2021 Apr;109(2):174-200

Emerging Technology and Innovation Strategist, University of Minnesota, Minneapolis, MN.

Background: Literature searches underlie the foundations of systematic reviews and related review types. Yet, the literature searching component of systematic reviews and related review types is often poorly reported. Guidance for literature search reporting has been diverse and, in many cases, does not offer enough detail to authors who need more specific information about reporting search methods and information sources in a clear, reproducible way. Read More

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Pakistan Oral Cancer Collaborative: analyzing barriers and obstacles to oral cancer diagnosis, treatment, and prevention in Pakistan.

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 May 13:4623. Epub 2021 May 13.

Senior Clinical Lecturer and Consultant Pathologist, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. Electronic address:

Oral cancer is a global health problem with increasing case numbers worldwide and no significant improvement in prognosis over the last few decades. It is one of the most common cancers and a leading cause of death in Pakistan, although the number reported is significantly underreported owing to the lack of a national cancer repository, and the true magnitude of this challenge is not known. Bilateral discussions and workshops funded by the Global Challenges Research Fund brought together a number of like-minded researchers and clinicians from the United Kingdom and Pakistan to analyze the status quo and plan the future course. Read More

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Stakeholder point of view on prescription drug affordability - a systematic literature review and content analysis.

Health Policy 2021 Jul 9. Epub 2021 Jul 9.

Director, Policy Evidence Research CORE, Merck & Co. Inc., Kenilworth, NJ, USA. Electronic address:

Objectives: The objectives of this research were to: 1) understand perspectives on affordability of pharmaceutical drugs from the point of view of stakeholders as reported in published peer-reviewed journals and conferences; 2) evaluate if (and how) perspectives on affordability overlapped across stakeholders.

Methods: The systematic literature review followed Cochrane and PRISMA guidelines. Content analysis with iterative and systematic coding of text was conducted, to identify themes. Read More

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The RAND/PPMD Patient-Centeredness Method: a novel online approach to engaging patients and their representatives in guideline development.

Eur J Pers Cent Healthc 2019 21;7(3):470-475. Epub 2019 Nov 21.

Assistant Professor, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.

Although clinical practice guidelines (CPGs) provide recommendations for how best to treat a typical patient with a given condition, patients and their representatives are not always engaged in CPG development. Despite the agreement that patient participation may improve the quality and utility of CPGs, there is no systematic, scalable method for engaging patients and their representatives, as well as no consensus on what exactly patients and their representatives should be asked to do during CPG development. To address these gaps, an interdisciplinary team of researchers, patient representatives, and clinicians developed the RAND/PPMD Patient-Centeredness Method (RPM) - a novel online approach to engaging patients and their representatives in CPG development. Read More

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November 2019

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1.

Authors:

Lancet 2021 Jul 14. Epub 2021 Jul 14.

Background: Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. Read More

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Real-World Cost of Care for Commercially Insured versus Medicare Patients with Metastatic Pancreatic Cancer Who Received Guideline-Recommended Therapies.

Am Health Drug Benefits 2021 Jun;14(2):70-78

Chief, GI Cancer Section, Associate Professor, Medical Faculty Associates, George Washington University, Washington, DC.

Background: Much of the literature about the costs of metastatic pancreatic cancer is focused on the Medicare population, but the cost in the commercially insured population is not well-documented. Differences in treatment patterns between commercially insured and Medicare patients with metastatic pancreatic cancer can provide insights into healthcare utilization and the total cost of care.

Objective: To compare the total cost of care for commercially insured versus Medicare patients with metastatic pancreatic cancer who are receiving National Comprehensive Cancer Network (NCCN)-recommended treatment regimens. Read More

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Insights from Real-World Analysis of Treatment Patterns in Patients with Newly Diagnosed Knee Osteoarthritis.

Am Health Drug Benefits 2021 Jun;14(2):56-62

Director, Medical Affairs, Ferring Pharmaceuticals.

Background: Several nonpharmacologic and pharmacologic treatments are available for the management of knee osteoarthritis (OA)-related pain and for improving functionality; however, clinical guideline recommendations vary on their use.

Objective: To compare the treatment patterns in a real-world setting versus the guideline recommendations for the treatment of newly diagnosed patients with knee OA.

Methods: This retrospective analysis used data from the electronic health records of the Geisinger Health System between January 1, 2010, and December 2018 to identify adults with newly diagnosed knee OA who had not received previous therapy with intra-articular corticosteroids, opioids, intra-articular hyaluronic acid, or prescription nonsteroidal anti-inflammatory drugs (NSAIDs). Read More

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Progressive exercise compared with best practice advice, with or without corticosteroid injection, for the treatment of patients with rotator cuff disorders (GRASP): a multicentre, pragmatic, 2 × 2 factorial, randomised controlled trial.

Lancet 2021 Jul 12. Epub 2021 Jul 12.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; College of Medicine and Health, University of Exeter, Exeter, UK.

Background: Corticosteroid injections and physiotherapy exercise programmes are commonly used to treat rotator cuff disorders but the treatments' effectiveness is uncertain. We aimed to compare the clinical effectiveness and cost-effectiveness of a progressive exercise programme with a single session of best practice physiotherapy advice, with or without corticosteroid injection, in adults with a rotator cuff disorder.

Methods: In this pragmatic, multicentre, superiority, randomised controlled trial (2 × 2 factorial), we recruited patients from 20 UK National Health Service trusts. Read More

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Treatment of keloids and hypertrophic scars. Position statement of the Brazilian expert group GREMCIQ.

J Eur Acad Dermatol Venereol 2021 Jul 15. Epub 2021 Jul 15.

Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.

Keloids (K) and hypertrophic scars (HS) are abnormal responses to wound healing that occur as the result of dermal inflammation. Despite the advances on their treatment, many patients still suffer from the negative effects of excessive scarring; its approach is impaired by the lack of objective data on different treatments and the large genetic variability among patients and the difficulties in producing multicentre studies. Their incidence among the Brazilian population is high, as the result of an admixture of Amerindians, Europeans and Africans ancestral roots. Read More

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