70 results match your criteria semi-automated volumetry


Radioembolization versus portal vein embolization for contralateral liver lobe hypertrophy: effect of cirrhosis.

Abdom Radiol (NY) 2021 Mar 29. Epub 2021 Mar 29.

Department of Radiology, Dresden University Hospital, Fetscherstr. 74, 01307, Dresden, Germany.

Purpose: Preoperative hypertrophy induction of future liver remnant (FLR) reduces the risk of postoperative liver insufficiency after partial hepatectomy. One of the most commonly used methods to induce hypertrophy of FLR is portal vein embolization (PVE). Recent studies have shown that transarterial radioembolization (TARE) also induces hypertrophy of the contralateral liver lobe. Read More

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Inter-Reader Variability of Volumetric Subsolid Pulmonary Nodule Radiomic Features.

Acad Radiol 2021 Feb 17. Epub 2021 Feb 17.

Department of Radiology, NYU Langone Health (L.A., W.H.M., J.B., J.P.K.).

Objective: To evaluate the inter-observer consistency for subsolid pulmonary nodule radiomic features.

Materials And Methods: Subsolid nodules were selected by reviewing radiology reports of CT examinations performed December 1, 2015 to April 1, 2016. Patients with CTs at two time points were included in this study. Read More

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February 2021

Feasibility and possible value of quantitative semi-automated diffusion weighted imaging volumetry of neuroblastic tumors.

Cancer Imaging 2020 Dec 17;20(1):89. Epub 2020 Dec 17.

Department of Diagnostic and Interventional Radiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.

Background: To assess the feasibility and possible value of semi-automated diffusion weighted imaging (DWI) volumetry of whole neuroblastic tumors with apparent diffusion coefficient (ADC) map evaluation after neoadjuvant chemotherapy.

Methods: Pediatric patients who underwent surgical resection of neuroblastic tumors at our institution from 2013 to 2019 and who received a preoperative MRI scan with DWI after chemotherapy were included. Tumor volume was assessed with a semi-automated approach in DWI using a dedicated software prototype. Read More

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December 2020

Reporting radiographers and their role in thoracic CT service improvement: managing the pulmonary nodule.

BJR Open 2020 10;2(1):20190018. Epub 2020 Mar 10.

Department of Radiology, Nottingham City Hospital Campus, Nottingham University Hospitals, Nottingham, United Kingdom.

Objectives: The use of cross-sectional imaging in clinical medicine has been a major step forward in the management of many conditions but with that comes the increasing demand on resources and the detection of other potentially significant findings. This, in the context of a shortage of skilled radiologists, means that new ways of working are important. In thoracic CT, pulmonary nodules are a significant challenge because they are so common. Read More

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Hepatic volume profiles in potential living liver donors with anomalous right-sided ligamentum teres.

Abdom Radiol (NY) 2020 Oct 16. Epub 2020 Oct 16.

Division of Liver Transplantation and Hepatobiliary Surgery, and Departments of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Purpose: In living liver donors with rare anatomical anomaly of right-sided ligamentum teres (RSLT), right or left hemiliver procurement is commonly contraindicated. The purpose of this study was to evaluate the hepatic volume profiles in potential donors with RSLT using semi-automated CT volumetry (CTV).

Methods: Among 5535 potential donor candidates in our institution between April 2003 and May 2019, 23 cases of RSLT (0. Read More

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October 2020

A comparison between MRI and CT in the assessment of primary tumour volume in mesothelioma.

Lung Cancer 2020 12 1;150:12-20. Epub 2020 Oct 1.

Glasgow Pleural Disease Unit, Queen ElIzabeth University Hospital, Glasgow, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Electronic address:

Introduction: Primary tumour staging in Malignant Pleural Mesothelioma (MPM) using Computed Tomography (CT) imaging is confounded by perception errors reflecting low spatial resolution between tumour and adjacent structures. Augmentation using perfusion CT is constrained by radiation dosage. In this study, we evaluated an alternative tumour staging method using perfusion-tuned Magnetic Resonance Imaging (MRI). Read More

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December 2020

Manual segmentation versus semi-automated segmentation for quantifying vestibular schwannoma volume on MRI.

Int J Comput Assist Radiol Surg 2020 Sep 16;15(9):1445-1455. Epub 2020 Jul 16.

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Purpose: Management of vestibular schwannoma (VS) is based on tumour size as observed on T1 MRI scans with contrast agent injection. The current clinical practice is to measure the diameter of the tumour in its largest dimension. It has been shown that volumetric measurement is more accurate and more reliable as a measure of VS size. Read More

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September 2020

Magnetic resonance markers of bilateral neuronal metabolic dysfunction in patients with unilateral internal carotid artery occlusion.

MAGMA 2021 Feb 27;34(1):141-151. Epub 2020 Jun 27.

Department of Neurology, 2nd Faculty of Medicine, Charles University, Motol University Hospital, Prague, Czech Republic.

Objectives: To evaluate cerebral hemodynamic, metabolic and anatomic changes occurring in patients with unilateral occlusion of the internal carotid artery (ICA).

Materials And Methods: Twenty-two patients with unilateral occlusion of ICA and twenty age and sex matched healthy subjects were included in the study. Single voxel proton magnetic resonance spectroscopy (H-MRS) of the centrum semiovale, semi-automated hippocampal volumetry in T1-weighted scans and transcranial Doppler examination (TCD) with calculation of Breath Holding Index (BHI) were performed in both groups. Read More

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February 2021

Correlation between computed tomography volumetry and nuclear medicine split renal function in live kidney donation: a single-centre experience.

ANZ J Surg 2020 07 21;90(7-8):1347-1351. Epub 2020 Jun 21.

Department of Surgery, Central Adelaide Local Health Network, Adelaide, South Australia, Australia.

Background: Potential live renal donors undergo both renal computed tomography angiogram (CTA) and nuclear imaging dimercaptosuccinic acid (DMSA) scans. Each kidney's renal function and vascular anatomy influences the choice of donor side. Although DMSA measures differential blood flow, it is a surrogate for renal function and nephron mass. Read More

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The effect of pregnancy on growth-dynamics of neurofibromas in Neurofibromatosis type 1.

PLoS One 2020 28;15(4):e0232031. Epub 2020 Apr 28.

Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Introduction: Patients with Neurofibromatosis type 1 (NF1) develop plexiform neurofibromas (PNF) and cutaneous neurofibromas. These tumors are a major cause of the patient's morbidity and mortality. An influence of estrogen and progesterone on tumor growth has been suggested but reports on growth or malignant transformation of tumors during pregnancy remain anecdotal. Read More

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Semi-automated volumetry of MRI serves as a biomarker in neuromuscular patients.

Muscle Nerve 2020 05 17;61(5):600-607. Epub 2020 Feb 17.

Department of Neurology, University Hospital Aachen, Aachen, Germany.

Background: Muscle MRI is of increasing importance for neuromuscular patients to detect changes in muscle volume, fat-infiltration, and edema. We developed a method for semi-automated segmentation of muscle MRI datasets.

Methods: An active contour-evolution algorithm implemented within the ITK-SNAP software was used to segment T1-weighted MRI, and to quantify muscle volumes of neuromuscular patients (n = 65). Read More

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The orthogonal measurements approach in estimating spleen size on CT images.

Diagn Interv Radiol 2020 Jan;26(1):5-10

Department of Radiology, Erciyes University School of Medicine, Kayseri, Turkey.

Purpose: To find out which single measurement and/or linear regression model correlates well with splenic volume using the orthogonal measurements approach.

Methods: The study relied on retrospective analysis of 205 contrast-enhanced abdominal CT examinations carried out in adult patients using a 320-detector CT system. CT volumetry was conducted by a semi-automated, model and threshold based segmentation algorithm that enables voxel-based volume calculation of abdominal organs. Read More

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January 2020

Assessment of spatial tumor heterogeneity using CT growth patterns estimated by tumor tracking on 3D CT volumetry of multiple pulmonary metastatic nodules.

PLoS One 2019 1;14(8):e0220550. Epub 2019 Aug 1.

Division of Hematology/Oncology, Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

Purpose: Our purpose was to assess the differences in growth rates of multiple pulmonary metastatic nodules using three-dimensional (3D) computed tomography (CT) volumetry and propose a concept of CT spatial tumor heterogeneity.

Materials And Methods: We manually measured the largest diameter of metastatic pulmonary nodules on chest CT scans, and calculated the 3D maximum diameter and the volume using a semi-automated 3D CT volumetry of each nodule. The tumor response was assessed according to the revised RECIST 1. Read More

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A closer look at right ventricular 3D volume quantification by transthoracic echocardiography and cardiac MRI.

Clin Radiol 2019 06 4;74(6):490.e7-490.e14. Epub 2019 Apr 4.

Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Germany.

Aim: To compare right ventricular (RV) volumetry using state-of-the-art three-dimensional (3D) transthoracic echocardiography (3DE) and cardiac magnetic resonance imaging (CMR) near-simultaneously in a clinical setting.

Materials And Methods: Forty-seven consecutive patients received comprehensive echocardiography including 3DE within 30 minutes of CMR. RV volumetry was performed offline with semi-automated 3D endocardial border tracing as well as manual delineation of the compacted myocardium in short-axis views by CMR. Read More

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Semi-automated computed tomography Volumetry can predict hemihepatectomy specimens' volumes in patients with hepatic malignancy.

BMC Med Imaging 2019 02 26;19(1):20. Epub 2019 Feb 26.

Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.

Background: One of the major causes of perioperative mortality of patients undergoing major hepatic resections is post-hepatectomy liver failure (PHLF). For preoperative appraisal of the risk of PHLF it is important to accurately predict resectate volume and future liver remnant volume (FLRV). The objective of our study is to prospectively evaluate the accuracy of hemihepatectomy resectate volumes that are determined by computed tomography volumetry (CTV) when compared with intraoperatively measured volumes and weights as gold standard in patients undergoing hemihepatectomy. Read More

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February 2019

Accuracy of preoperative CT liver volumetry in living donor hepatectomy and its clinical implications.

Hepatobiliary Surg Nutr 2018 Jun;7(3):167-174

Institute of Liver Transplant and Regenerative Medicine, Medanta, The Medicity, Gurgaon, Delhi (NCR), India.

Background: An accurate preoperative volumetric assessment of donor liver is essential for successful living donor liver transplant by ensuring adequate remnant and graft recipient weight ratio (GRWR).

Methods: The study cohort consisted of 744 right lobe (RL), 65 left lobe (LL) and 33 left lateral sector (LLS) grafts from July 2010 to January 2014. A semi-automated interactive commercial software called AW Volume share 6 was used for volumetry. Read More

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CT attenuation of liver metastases before targeted therapy is a prognostic factor of overall survival in colorectal cancer patients. Results from the randomised, open-label FIRE-3/AIO KRK0306 trial.

Eur Radiol 2018 Dec 7;28(12):5284-5292. Epub 2018 Jun 7.

Department of Radiology, University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.

Objectives: To assess the prognostic value of pre-therapeutic computed tomography (CT) attenuation of liver metastases for overall survival (OS) in metastatic colorectal cancer (mCRC).

Methods: In the open-label, randomised, prospective phase-III FIRE-3 trial, patients with histologically confirmed mCRC received fluorouracil (5-FU), leucovorin and irinotecan (FOLFIRI) with either cetuximab or bevacizumab. Participating patients gave written informed consent prior to study entry. Read More

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December 2018

Can computed tomography volumetry of the renal cortex replace MAG3-scintigraphy in all patients for determining split renal function?

Eur J Radiol 2018 Jun 22;103:105-111. Epub 2018 Apr 22.

Institute of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany.

Objectives: The current gold standard for determination of split renal function (SRF) is Tc-99m-mercapto-acetyltriglycin (MAG3) scintigraphy. Initial studies comparing MAG3-scintigraphy and CT-based renal cortex volumetry (RCV) for calculation of SRF have shown similar results in highly selected patient collectives with normal renal function (i.e. Read More

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A semi-automated algorithm for hypothalamus volumetry in 3 Tesla magnetic resonance images.

Psychiatry Res Neuroimaging 2018 07 1;277:45-51. Epub 2018 May 1.

Department of Psychiatry and Psychotherapy, Leipzig University Hospital, Leipzig, Germany. Electronic address:

The hypothalamus, a small diencephalic gray matter structure, is part of the limbic system. Volumetric changes of this structure occur in psychiatric diseases, therefore there is increasing interest in precise volumetry. Based on our detailed volumetry algorithm for 7 Tesla magnetic resonance imaging (MRI), we developed a method for 3 Tesla MRI, adopting anatomical landmarks and work in triplanar view. Read More

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Reliable and fast volumetry of the lumbar spinal cord using cord image analyser (Cordial).

Eur Radiol 2018 Nov 30;28(11):4488-4495. Epub 2018 Apr 30.

Division of Diagnostic and Interventional Neuroradiology, Department of Radiology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.

Objective: To validate the precision and accuracy of the semi-automated cord image analyser (Cordial) for lumbar spinal cord (SC) volumetry in 3D T1w MRI data of healthy controls (HC).

Materials And Methods: 40 3D T1w images of 10 HC (w/m: 6/4; age range: 18-41 years) were acquired at one 3T-scanner in two MRI sessions (time interval 14.9±6. Read More

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November 2018

Pulmonary nodules: Assessing the imaging biomarkers of malignancy in a "coffee-break".

Eur J Radiol 2018 Apr 7;101:82-86. Epub 2018 Feb 7.

Oxford University Hospitals NHS Foundation Trust, UK.

Introduction: Although nodule volumetry is a recognized biomarker of malignancy in pulmonary nodules (PNs), caution is needed in its interpretation because of variables such as respiratory volume variation and inter-scan variability of up to 25%. CT Texture Analysis (CTTA) is a potential independent biomarker of malignancy but inter-scan variability and respiratory volume variation has not been assessed.

Methods: In this prospective cohort study, 40 patients (20 with an indeterminate PN and 20 with pulmonary metastases) underwent two LDCTs within a 60-min period (the "Coffee-break") with the aim of assessing the repeatability of CTTA and semi-automated volume measurements. Read More

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Urinary bladder volume measured in whole-body CT scans is a useful marker for alcohol intoxication.

Alcohol 2017 Dec 23;65:45-50. Epub 2017 Sep 23.

Institute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Ferdinand-Sauerbruch-Str., 17475 Greifswald, Germany. Electronic address:

Purpose: The aim of this study was to investigate whether urinary bladder volume (UBV) and blood alcohol concentration (BAC) correlate in a cohort of emergency trauma patients. Furthermore, the feasibility of semi-automated 3D-CT volumetry for urinary bladder volumetry calculations in whole-body CT examinations was elucidated.

Material And Methods: Whole-body CT scans of 831 individuals treated in the emergency department with suspected multiple injuries were included. Read More

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December 2017

Liver segmentation: indications, techniques and future directions.

Insights Imaging 2017 Aug 14;8(4):377-392. Epub 2017 Jun 14.

Department of Radiology, Radio-oncology and Nuclear Medicine, University of Montreal, Saint-Luc Hospital, 1058 rue Saint-Denis, Montreal, QC, H2X 3J4, Canada.

Objectives: Liver volumetry has emerged as an important tool in clinical practice. Liver volume is assessed primarily via organ segmentation of computed tomography (CT) and magnetic resonance imaging (MRI) images. The goal of this paper is to provide an accessible overview of liver segmentation targeted at radiologists and other healthcare professionals. Read More

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What are the true volumes of SEGA tumors? Reliability of planimetric and popular semi-automated image segmentation methods.

MAGMA 2017 Aug 20;30(4):397-405. Epub 2017 Mar 20.

Department of Pediatrics, Oncology, Hematology and Diabetology, University Hospital No 4, Lodz, Poland.

Objective: To evaluate the reliability of the standard planimetric methodology of volumetric analysis and three different open-source semi-automated approaches of brain tumor segmentation.

Materials And Methods: The volumes of subependymal giant cell astrocytomas (SEGA) examined by 30 MRI studies of 10 patients from a previous everolimus-related trial (EMINENTS study) were estimated using four methods: planimetric method (modified MacDonald ellipsoid method), ITK-Snap (pixel clustering, geodesic active contours, region competition methods), 3D Slicer (level-set thresholding), and NIRFast (k-means clustering, Markov random fields). The methods were compared, and a trial simulation was performed to determine how the choice of approach could influence the final decision about progression or response. Read More

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Progressive disease in glioblastoma: Benefits and limitations of semi-automated volumetry.

PLoS One 2017 28;12(2):e0173112. Epub 2017 Feb 28.

Department of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Germany.

Purpose: Unambiguous evaluation of glioblastoma (GB) progression is crucial, both for clinical trials as well as day by day routine management of GB patients. 3D-volumetry in the follow-up of GB provides quantitative data on tumor extent and growth, and therefore has the potential to facilitate objective disease assessment. The present study investigated the utility of absolute changes in volume (delta) or regional, segmentation-based subtractions for detecting disease progression in longitudinal MRI follow-ups. Read More

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Semi-automatic Volumetric Measurement of Treatment Response in Hepatocellular Carcinoma After Trans-arterial Chemoembolization.

Anticancer Res 2016 Aug;36(8):4353-8

Department of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Aim: To perform a quantitative, volumetric analysis of therapeutic effects of trans-arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) patients.

Patients And Methods: Entire tumor volume and a subset of hypervascular tumor portions were analyzed pre- and post-TACE in magnetic resonance imaging datasets of 22 HCC patients using a semi-automated segmentation and evaluation tool from the Medical Imaging Interaction Toolkit. Results were compared to mRECIST measurements and inter-reader variability was assessed. Read More

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Algorithm Variability in the Estimation of Lung Nodule Volume From Phantom CT Scans: Results of the QIBA 3A Public Challenge.

Acad Radiol 2016 08 20;23(8):940-52. Epub 2016 May 20.

Buckler Biomedical Associates LLC, Massachusetts, USA.

Rationale And Objectives: Quantifying changes in lung tumor volume is important for diagnosis, therapy planning, and evaluation of response to therapy. The aim of this study was to assess the performance of multiple algorithms on a reference data set. The study was organized by the Quantitative Imaging Biomarker Alliance (QIBA). Read More

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Semi-automatic 3D-volumetry of liver metastases from neuroendocrine tumors to improve combination therapy with 177Lu-DOTATOC and 90Y-DOTATOC.

Diagn Interv Radiol 2016 May-Jun;22(3):201-6

Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.

Purpose: Patients with neuroendocrine tumors (NET) often present with disseminated liver metastases and can be treated with a number of different nuclides or nuclide combinations in peptide receptor radionuclide therapy (PRRT) depending on tumor load and lesion diameter. For quantification of disseminated liver lesions, semi-automatic lesion detection is helpful to determine tumor burden and tumor diameter in a time efficient manner. Here, we aimed to evaluate semi-automated measurement of total metastatic burden for therapy stratification. Read More

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Automated and Semiautomated Segmentation of Rectal Tumor Volumes on Diffusion-Weighted MRI: Can It Replace Manual Volumetry?

Int J Radiat Oncol Biol Phys 2016 Mar 17;94(4):824-31. Epub 2015 Dec 17.

GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Purpose: Diffusion-weighted imaging (DWI) tumor volumetry is promising for rectal cancer response assessment, but an important drawback is that manual per-slice tumor delineation can be highly time consuming. This study investigated whether manual DWI-volumetry can be reproduced using a (semi)automated segmentation approach.

Methods And Materials: Seventy-nine patients underwent magnetic resonance imaging (MRI) that included DWI (highest b value [b1000 or b1100]) before and after chemoradiation therapy (CRT). Read More

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Reliability of Semi-Automated Segmentations in Glioblastoma.

Clin Neuroradiol 2017 Jun 21;27(2):153-161. Epub 2015 Oct 21.

Department of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.

Purpose: In glioblastoma, quantitative volumetric measurements of contrast-enhancing or fluid-attenuated inversion recovery (FLAIR) hyperintense tumor compartments are needed for an objective assessment of therapy response. The aim of this study was to evaluate the reliability of a semi-automated, region-growing segmentation tool for determining tumor volume in patients with glioblastoma among different users of the software.

Methods: A total of 320 segmentations of tumor-associated FLAIR changes and contrast-enhancing tumor tissue were performed by different raters (neuroradiologists, medical students, and volunteers). Read More

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