1,819 results match your criteria self-poisoning


Cardiac arrest following unsuspected self-poisoning with doxylamine.

Ther Drug Monit 2022 Jan 11. Epub 2022 Jan 11.

Clinical Toxicology Unit, Clinical Analysis Department. Hospital Universitari Son Llàtzer. Research Institute of Health Sciences (IdISBa). Palma de Mallorca, Spain. Intensive Care Department. Hospital Universitari Son Llàtzer. Research Institute of Health Sciences (IdISBa). Palma de Mallorca, Spain. Intensive Care Department. Hospital Universitari Son Llàtzer. Research Institute of Health Sciences (IdISBa). Palma de Mallorca, Spain. Intensive Care Department. Hospital Universitari Son Llàtzer. Research Institute of Health Sciences (IdISBa). Palma de Mallorca, Spain. Cardiology Department. Hospital Universitari Son Llàtzer. Department of Medicine, Faculty of Medicine, University of the Balearic Islands. Research Institute of Health Sciences (IdISBa). Palma de Mallorca, Spain. Institute of Legal Medicine of the Balearic Islands. Ministry of Justice. Department of Medicine, Faculty of Medicine, University of the Balearic Islands. Palma de Mallorca, Spain. Institute of Legal Medicine of the Balearic Islands. Ministry of Justice. Department of Medicine, Faculty of Medicine, University of the Balearic Islands. Palma de Mallorca, Spain.

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January 2022

Serotonin syndrome after an overdose of over-the-counter medicine containing dextromethorphan.

J Gen Fam Med 2022 Jan 4;23(1):38-40. Epub 2021 Jun 4.

Department of General Internal Medicine Akashi Medical Center Hyogo Japan.

Serotonin syndrome is a potentially life-threatening adverse reaction from therapeutic drug use, intentional self-poisoning, or inadvertent interactions between drugs. We report a case of the serotonin syndrome after an overdose of a commonly available over-the-counter cough medicine, . Over-the-counter drugs containing dextromethorphan may, in rare cases, cause health problems requiring hospitalization or worse. Read More

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January 2022

CON: Oximes should be used routinely in organophosphorus insecticide poisoning.

Br J Clin Pharmacol 2022 Jan 5. Epub 2022 Jan 5.

Pharmacology, Therapeutics & Toxicology, Centre for Cardiovascular Science, and Centre for Pesticide Suicide Prevention, University of Edinburgh, Edinburgh, UK.

Organophosphorus (OP) insecticide poisoning causes respiratory failure due to acetylcholinesterase (AChE) inhibition. The AChE reactivating antidote pralidoxime was developed in the 1950s and soon noted to benefit patients occupationally poisoned with the highly potent OP insecticide parathion. Routine use of pralidoxime and other oximes such as obidoxime then became widely recommended. Read More

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January 2022

Characteristics and psychopathology of 1,086 patients who self-poisoned using pesticides in Taiwan (2012-2019): A comparison across pesticide groups.

J Affect Disord 2021 Dec 21;300:17-26. Epub 2021 Dec 21.

South Asian Clinical Toxicology Research Collaboration, University of Peradeniya, Peradeniya, Sri Lanka; Institute of Health Behaviors and Community Sciences and Global Health Program, and College of Public Health, National Taiwan University, Taipei, Taiwan; Psychiatric Research Center, Wan Fang Hospital, Taipei Medical University, Taipei City, Taiwan. Electronic address:

Background Previous studies, mainly from low- and middle-income settings, showed that pesticide self-poisonings were mostly impulsive with low levels of psychopathology. We aimed to investigate whether pesticide self-poisoning in a high-income country showed similar profiles, and whether those with certain characteristics and psychopathology were more likely to use specific pesticides. Methods Data were extracted from hospital records of pesticide self-poisoning patients treated at eight major hospitals in Taiwan between 2012 and 2019. Read More

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December 2021

Changes of attention-related brain activity over 6 months after acute organophosphate pesticide poisoning: a prospective follow-up study.

Clin Toxicol (Phila) 2021 Dec 14:1-9. Epub 2021 Dec 14.

South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Context: Ingestion of organophosphate (OP) pesticides is a common method of self-harm in developing countries. Apart from acute cholinergic effects, limited evidence implicates OP poisoning in long-term neurocognitive deficits. However, prospective neurophysiological evidence of long-term deficits is scarce in humans. Read More

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December 2021

Acute organophosphate and carbamate pesticide poisonings - a five-year survey from the National Poison Control Center Of Serbia.

Drug Chem Toxicol 2021 Dec 7:1-9. Epub 2021 Dec 7.

Center for Biomedical Research, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.

Pesticide poisonings, intentional as well as accidental, are common, especially in undeveloped and developing countries. The goal of this study was to analyze the clinical presentation of patients hospitalized due to acute organophosphate (OPP) or carbamate pesticide (CP) poisoning as well as to analyze the factors that potentially influenced the severity and outcome of the poisonings. A retrospective cross-sectional study was performed. Read More

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December 2021

Tuning Metal-Support Interaction of Pt-CeO Catalysts for Enhanced Oxidation Reactivity.

Environ Sci Technol 2021 12 30;55(24):16687-16698. Epub 2021 Nov 30.

State Key Joint Laboratory of Environment Simulation and Pollution Control, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.

Metal-support interaction (MSI) has been widely recognized to be playing a pivotal role in regulating the catalytic activity of various reactions. In this work, the degree of MSI between Pt and CeO support was finely tuned by adjusting the activation condition, and the obtained catalysts were tested for the oxidative abatement of CO and HCHO under ambient conditions. The characterization of catalysts shows that activation of strongly interacting Pt-CeO at higher temperatures by H leads to a weaker MSI with increased electron density of Pt, and this modification of local electronic properties is demonstrated to result in enhanced O adsorption/activation to prevent the CO self-poisoning effect, while it abates the activity of CO adsorption/activation and oxidation of adsorbed CO. Read More

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December 2021

Osmolal and anion gaps after acute self-poisoning with agricultural formulations of the organophosphorus insecticides profenofos and diazinon: A pilot study.

Basic Clin Pharmacol Toxicol 2022 Feb 3;130(2):320-327. Epub 2021 Dec 3.

South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Self-poisoning with organophosphorus (OP) insecticides is an important means of global self-harm. The insecticides are formulated with solvents that may also contribute to toxicity. We set up a study to detect changes in osmolal and anion gaps following ingestion of OP insecticides. Read More

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February 2022

Platinum-Tin/Tin Oxide/CNT Catalysts for High-Performance Electrocatalytic Ethanol Oxidation.

Chemistry 2021 Nov 17. Epub 2021 Nov 17.

State Key Laboratory of Physical Chemistry of Solid Surfaces and Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, Fujian, P. R. China.

Ethanol is a promising liquid clean energy source in the energy conversion field. However, the self-poisoning caused by the strongly adsorbed reaction intermediates (typically, CO) is a critical problem in ethanol oxidation reaction. To address this issue, we proposed a joint use of two strategies, alloying of Pt with other metals and building Pt/metal-oxide interfaces, to achieve high-performance electrocatalytic ethanol oxidation. Read More

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November 2021

Self-poisoning as a cause of admission in a medical intensive care unit and a question of misuse of prescription medications.

Heart Lung 2021 Oct 29;51:17-21. Epub 2021 Oct 29.

School of Medicine, University of Zagreb, Šalata 3, Zagreb 10000, Croatia; Department of Internal Medicine, Division of Intensive Care Medicine, University Hospital Centre Zagreb, Kišpatićeva 12, Zagreb 10000, Croatia.

Background: Self-poisoning accounts for between 3 and 17% of intensive care unit (ICU) admissions.

Objectives: To display the misused substances, intention, and outcome of patients admitted to the ICU due to self-poisoning.

Methods: A retrospective review of ICU admissions using an electronic patient database was performed. Read More

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October 2021

Self-harm in children and adolescents by ethnic group: an observational cohort study from the Multicentre Study of Self-Harm in England.

Lancet Child Adolesc Health 2021 11 21;5(11):782-791. Epub 2021 Sep 21.

Centre for Mental Health and Safety, School of Health Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK; The National Institute for Health Research Greater Manchester Patient Safety Translational Research Centre, Manchester, UK.

Background: Studies report an increasing incidence of self-harm in children and adolescents, but the extent to which this is seen in different ethnic groups is unclear. We aimed to investigate rates of emergency department presentations for self-harm in children and adolescents by ethnicity, as well as to examine their demographic characteristics, clinical characteristics, and outcomes.

Methods: In this observational cohort study, we used data on hospital emergency department presentations for self-harm in children and adolescents aged 10-19 years between 2000 and 2016 from the Multicentre Study of Self-harm in England. Read More

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November 2021

Factors associated with paediatric and adolescent Emergency Department presentations involving acute behavioural disturbance events.

J Paediatr Child Health 2021 Aug 10. Epub 2021 Aug 10.

School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.

Aim: Studies reporting factors associated with paediatric/adolescent acute behavioural disturbance (ABD) in the Emergency Department (ED) are lacking. The aim of this study is to describe paediatric/adolescent ED presentations involving ABD events.

Methods: A retrospective chart review of presentations involving ABD events, identified via hospital security log, to a tertiary referral paediatric ED during the 2017 calendar year. Read More

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Recommendations from the EXTRIP workgroup on extracorporeal treatment for baclofen poisoning.

Kidney Int 2021 10 4;100(4):720-736. Epub 2021 Aug 4.

Emergency Medicine Department, Centre Intégré de Santé et de Services Sociaux (CISSS) de la Montérégie-Centre, Hôpital Charles-LeMoyne, Greenfield Park, Québec, Canada; Academic Emergency Medicine Department, Faculty of Medicine, McGill University, Montréal, Québec, Canada; Centre Antipoison du Québec, Québec, Québec, Canada. Electronic address:

Baclofen toxicity results from intentional self-poisoning (acute baclofen poisoning) or accumulation of therapeutic dose in the setting of impaired kidney function. Standard care includes baclofen discontinuation, respiratory support and seizure treatment. Use of extracorporeal treatments (ECTRs) is controversial. Read More

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October 2021

Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study.

PLoS One 2021 6;16(8):e0255805. Epub 2021 Aug 6.

Department of Psychiatry, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

Psychiatric disorders are important predictors of deliberate self-harm. The present study was carried out to determine the associations between DSM-IV TR Axis- I & II disorders and deliberate self-poisoning (DSP) in a rural agricultural district in Sri Lanka. Patients residing in the district who presented with DSP were randomly selected for the study. Read More

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December 2021

Prevalence and risk factors for repetition of non-fatal self-harm in Hong Kong, 2002-2016: A population-based cohort study.

Lancet Reg Health West Pac 2020 Sep 12;2:100027. Epub 2020 Sep 12.

Department of Social Work and Social Administration, Centre for Suicide Research and Prevention, The University of Hong Kong, Hong Kong, China.

Background: A history of self-harm is strongly associated with future self-harm attempts. Large-scale Asian cohort studies examining risk factors for repeated self-harm are lacking. This paper reports on annual prevalence, cumulative risk, annual risk of non-fatal self-harm repetition, and risk factors among Hong Kong patients with a history of self-harm. Read More

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September 2020