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Promoting Smoking Cessation in China: Using an Expansion of the EPPM with Other-oriented Threat.

J Health Commun 2021 Apr 6:1-10. Epub 2021 Apr 6.

School of Journalism and Communication, Tsinghua University, China.

This study explored strategies to increase Chinese smokers' cessation intentions, using the extended parallel processing model, or EPPM. A 2 × 2 × 2 factorial experiment was designed to examine the effects of self-oriented threat (present vs. absent), other-oriented threat (present vs. Read More

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The Mentalized Affectivity Scale (MAS): Development and validation of the Italian version.

PLoS One 2021 5;16(4):e0249272. Epub 2021 Apr 5.

Research Unit on Theory of Mind, Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.

This study proposes a psychometric validation of the Italian version of the Mentalized Affectivity Scale (MAS) developed by Greenberg and colleagues in 2017. The mentalized affectivity construct integrates mentalization ability in the process of emotional regulation. An adult sample (N = 506) completed the 60-items MAS online version. Read More

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Enhanced amygdala-frontal operculum functional connectivity during rest in women with chronic neck pain: Associations with impaired conditioned pain modulation.

Neuroimage Clin 2021 Mar 22;30:102638. Epub 2021 Mar 22.

Department of Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Ghent University, Belgium; Department of Rehabilitation Medicine, Maastricht University, Maastricht, Netherlands; Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA, United States. Electronic address:

Background: Chronic neck pain is a leading cause of disability worldwide, affecting the lives of millions of people. Research investigating functional brain alterations in relation to somatosensory function is necessary to better understand mechanisms underlying pain development and maintenance in individuals with chronic neck pain, yet remains scarce. This case-control study aimed to examine resting-state functional connectivity alterations and associations with pain outcomes, self-reported central sensitization-related symptoms and quantitative sensory testing (QST) measures in patients with chronic non-traumatic (idiopathic/CINP) neck pain and chronic traumatic (whiplash associated/CWAD) neck pain compared to pain-free controls. Read More

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Self-Regulation in Informal Workplace Learning: Influence of Organizational Learning Culture and Job Characteristics.

Front Psychol 2021 10;12:643748. Epub 2021 Mar 10.

Abt. Lehr-Lernforschung, Universität Ulm, Ulm, Germany.

The digital shift leads to increasing changes. Employees can deal with changes through informal learning that enables needs-based development. For successful informal learning, self-regulated learning (SRL) is crucial, i. Read More

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Redox-sensitive carrier-free nanoparticles self-assembled by disulfide-linked paclitaxel-tetramethylpyrazine conjugate for combination cancer chemotherapy.

Theranostics 2021 20;11(9):4171-4186. Epub 2021 Feb 20.

College of Materials Science and Engineering, Nanjing Tech Universit`y, Nanjing 211816, People's Republic of China.

Combinations of two or more therapeutic agents targeting different signaling pathways involved in tumor progression can have synergistic anticancer effects. However, combination chemotherapies are greatly limited by the different pharmacokinetics, tumor targeting, and cellular uptake capacities of the combined drugs. We have previously demonstrated the potential synergistic efficacy of paclitaxel (PTX) and the natural anti-angiogenic agent tetramethylpyrazine (TMP) for suppressing ovarian carcinoma growth. Read More

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February 2021

Association of Olfactory Training With Neural Connectivity in Adults With Postviral Olfactory Dysfunction.

JAMA Otolaryngol Head Neck Surg 2021 Mar 18. Epub 2021 Mar 18.

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri.

Importance: Viral upper respiratory tract infections are a major cause of olfactory loss. Olfactory training (OT) is a promising intervention for smell restoration; however, a mechanistic understanding of the changes in neural plasticity induced by OT is absent.

Objective: To evaluate functional brain connectivity in adults with postviral olfactory dysfunction (PVOD) before and after OT using resting-state functional magnetic resonance imaging. Read More

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Across-subjects multiple baseline trial of exposure-based cognitive-behavioral therapy for severe irritability: a study protocol.

BMJ Open 2021 Mar 10;11(3):e039169. Epub 2021 Mar 10.

Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA.

Introduction: Irritability is defined as a tendency towards anger in response to frustration. Clinically, impairing irritability is a significant public health problem. There is a need for mechanism-based psychotherapies targeting severe irritability as it manifests in the context of disruptive mood dysregulation disorder (DMDD). Read More

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Internet-Administered Emotional Awareness and Expression Therapy for Somatic Symptom Disorder With Centralized Symptoms: A Preliminary Efficacy Trial.

Front Psychiatry 2021 12;12:620359. Epub 2021 Feb 12.

Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.

There is growing evidence that trauma, psychosocial conflict, and difficulties with emotional processing contribute to centralized somatic symptoms. Emotional Awareness and Expression Therapy (EAET) was developed to address these factors and reduce symptoms, and EAET has shown efficacy in face-to-face formats. No trial of an internet-delivered EAET (I-EAET) exists, however, so we developed such an intervention and conducted an uncontrolled feasibility and potential efficacy trial of I-EAET for patients with Somatic Symptom Disorder (SSD) with centralized symptoms (SSD-CS). Read More

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February 2021

Intact pain modulation through manipulation of controllability and expectations in aging.

Eur J Pain 2021 Mar 5. Epub 2021 Mar 5.

Cognitive and Affective Neuroscience and Clinical Psychology, Research Institute of Health Sciences (IUNICS) and Balearic Islands Health Research Institute (IdISBa), University of the Balearic Islands (UIB), Palma, Spain.

Background: Pain expectation and controllability can modulate pain processing. However, little is known about age-related effects on these cognitive factors involved in pain control. This study assessed age-related brain changes associated with pain expectation and controllability. Read More

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Cetuximab-conjugated perfluorohexane/gold nanoparticles for low intensity focused ultrasound diagnosis ablation of thyroid cancer treatment.

Sci Technol Adv Mater 2021 Feb 1;21(1):856-866. Epub 2021 Feb 1.

Department of Ultrasound, Harbin Medical University Cancer Hospital, P.R. China.

We report the formulation of nanoassemblies (NAs) comprising C225 conjugates Au-PFH-NAs (C-Au-PFH-NAs) for low-intensity focused ultrasound diagnosis ablation of thyroid cancer. C-Au-PFH-NAs showed excellent stability in water, phosphate-buffered saline (PBS), and 20% rat serum. Transmission electron microscopy (TEM) images also revealed the effective construction of C-Au-PFH-NAs as common spherical assemblies. Read More

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February 2021

Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells.

World J Stem Cells 2020 Dec;12(12):1511-1528

Biomedical Research Institute, MEDIPOST Co., Ltd., Seongnam 13494, South Korea.

Umbilical cord blood (UCB) is a primitive and abundant source of mesenchymal stem cells (MSCs). UCB-derived MSCs have a broad and efficient therapeutic capacity to treat various diseases and disorders. Despite the high latent self-renewal and differentiation capacity of these cells, the safety, efficacy, and yield of MSCs expanded for clinical applications remains a concern. Read More

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December 2020

Efficacy of Cognitive Training When Translated From the Laboratory to the Real World.

Mil Med 2021 01;186(Suppl 1):176-183

The University of Texas at Dallas Center for BrainHealth, Dallas, TX 75235, USA.

Introduction: Research shows that cognitive performance and emotional well-being can be significantly strengthened. A high-performance brain training protocol, Strategic Memory Advanced Reasoning Training (SMART), was developed by cognitive neuroscientists at The University of Texas at Dallas Center for BrainHealth based on 25-plus years of scientific study. Randomized controlled trials with various populations have shown that training and use of nine "SMART" strategies for processing information can improve cognitive performance and psychological health. Read More

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January 2021

Study design for a randomized clinical trial of cognitive-behavioral therapy for posttraumatic headache.

Contemp Clin Trials Commun 2021 Mar 6;21:100699. Epub 2021 Jan 6.

Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center San Antonio, San Antonio, TX, USA.

Posttraumatic headache (PTH) is a common debilitating condition arising from head injury and is highly prevalent among military service members and veterans with traumatic brain injury (TBI). Diagnosis and treatment for PTH is still evolving, and surprisingly little is known about the putative mechanisms that drive these headaches. This manuscript describes the design of a randomized clinical trial of two nonpharmacological (i. Read More

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Development and Validation of a Questionnaire on Consumer Psychological Capital in Food Safety Social Co-governance.

Front Psychol 2020 7;11:584810. Epub 2021 Jan 7.

School of Public Health and Management, Chongqing Medical University, Chongqing, China.

Consumers play an important role as one of the main actors in food safety social co-governance. To create a pattern of food safety social co-governance, the active and effective participation of consumers is critical. To encourage consumers to participate in food safety social co-governance voluntarily and positively, we attempted to develop and preliminarily validate a multidimensional questionnaire on consumer psychological capital that could be used to measure the degree of consumer participation in food safety social co-governance. Read More

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January 2021

Efficacy of Group Cognitive Behavior Therapy Targeting Time Management for Adults with Attention Deficit/Hyperactivity Disorder in Japan: A Randomized Control Pilot Trial.

J Atten Disord 2021 Jan 20:1087054720986939. Epub 2021 Jan 20.

Kyushu University, Fukuoka, Japan.

Objective: Time-processing disorders in adults is a priority area for intervention. Time management program, which has been demonstrated to be effective in children with ADHD, has not been examined in adults. We anticipate the need for the development of specialized programs for adults. Read More

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January 2021

Self-organized operational neural networks for severe image restoration problems.

Neural Netw 2021 Mar 23;135:201-211. Epub 2020 Dec 23.

Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland.

Discriminative learning based on convolutional neural networks (CNNs) aims to perform image restoration by learning from training examples of noisy-clean image pairs. It has become the go-to methodology for tackling image restoration and has outperformed the traditional non-local class of methods. However, the top-performing networks are generally composed of many convolutional layers and hundreds of neurons, with trainable parameters in excess of several million. Read More

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School Satisfaction in Immigrant and Chilean Students: The Role of Prejudice and Cultural Self-Efficacy.

Front Psychol 2020 10;11:613585. Epub 2020 Dec 10.

Faculty of Psychology, University of the Basque Country, Donostia-San Sebastián, Spain.

Latin-American immigration has transformed Chilean schools into new multicultural scenarios. Studies about intergroup dynamics among students from different cultural backgrounds and their psychological consequences are still limited in south-south migration contexts. Literature has suggested that intergroup relations influence students' satisfaction with school, and they could be improved by the development of competences to cope with cultural differences. Read More

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December 2020

A Multimodal Stress-Prevention Program Supplemented by Telephone-Coaching Sessions to Reduce Perceived Stress among German Farmers: Results from a Randomized Controlled Trial.

Int J Environ Res Public Health 2020 12 10;17(24). Epub 2020 Dec 10.

Chair of Public Health and Health Services Research, Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

This study compared the effectiveness of a 12-day stress-prevention program (SGS) supplemented by individualized, structured, four-session telephone-coaching to that of an SGS without telephone-coaching in entrepreneurs from the green professions presenting with increased stress levels. All participants went through the SGS before being randomized either to the telephone-coaching group (TC) or to the control group without telephone-coaching (noTC). SGS included four key therapeutic elements: stress-management intervention, relaxation, physical exercise, and balneotherapy. Read More

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December 2020

A context-adaptive smoking cessation system using videos.

Smart Health (Amst) 2021 Mar 21;19. Epub 2020 Nov 21.

Department of Electrical, Computer, and System Engineering, Case Western Reserve University, Cleveland, OH, USA.

Cigarette smoking is the primary preventable cause of death and disease worldwide. Studies reveal that smoking is associated with psychiatric symptoms, sociodemographic characteristics, social stressors, and lack of social support. In general, smokers report poorer mental health and benefit from support to be able to quit smoking (Jorm et al. Read More

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The role of self-efficacy and information processing in weight loss during an mHealth behavioral intervention.

Digit Health 2020 Jan-Dec;6:2055207620976755. Epub 2020 Nov 30.

Holcombe Department of Electrical and Computer Engineering, Clemson University, Clemson, USA.

Self-efficacy (SE) and information processing (IP) may be important constructs to target when designing mHealth interventions for weight loss. The goal of this study was to examine the relationship between SE and IP with weight loss at six-months as part of the Dietary Interventions Examining Tracking with mobile study, a six-month randomized trial with content delivered remotely via twice-weekly podcasts. Participants were randomized to self-monitor their diet with either a mobile app (n = 42) or wearable Bite Counter device (n = 39). Read More

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November 2020

Health information helps mitigate adolescent depression: A multivariate analysis of the links between health information use and depression management.

Bu Zhong Juan Chen

Child Care Health Dev 2021 03 16;47(2):201-207. Epub 2021 Jan 16.

School of Journalism and Communication, South China University of Technology, Guangzhou Higher Education Mega Center, Guangzhou, China.

Background: Depression has brought a range of detrimental effects on adolescents. Despite the identified adverse outcomes, it is unclear what mechanisms contribute to the onset of adolescent depression. The limitation calls for innovative ways of managing the mental disorder, including embedding the methods and concepts from the humanities and social sciences into caring depressed teens. Read More

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Efficacy of high-intensity aerobic exercise on cognitive performance in people with multiple sclerosis: A randomized controlled trial.

Mult Scler 2020 Nov 24:1352458520973619. Epub 2020 Nov 24.

Exercise Biology, Department of Public Health, Aarhus University, Aarhus C, Denmark.

Background: Cognitive impairment is highly prevalent in multiple sclerosis (MS). Progressive aerobic exercise (PAE) represents a promising approach toward preservation or even improvement of cognitive performance in people with MS (pwMS).

Objective: To investigate the effects of PAE on the cognitive domains of information processing, learning and memory, and verbal fluency in pwMS. Read More

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November 2020

The Role of Social Reward and Corticostriatal Connectivity in Substance Use.

J Psychiatr Brain Sci 2020 29;5. Epub 2020 Oct 29.

Department of Psychology, Temple University, Philadelphia, PA 19122, USA.

This report describes an ongoing R03 grant that explores the links between trait reward sensitivity, substance use, and neural responses to social and nonsocial reward. Although previous research has shown that trait reward sensitivity and neural responses to reward are linked to substance use, whether this relationship is impacted by how people process social stimuli remains unclear. We are investigating these questions via a neuroimaging study with college-aged participants, using individual difference measures that examine the relation between substance use, social context, and trait reward sensitivity with tasks that measure reward anticipation, strategic behavior, social reward consumption, and the influence of social context on reward processing. Read More

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October 2020

Changes in brain activity associated with cognitive-behavioral exposure therapy for specific phobias: searching for underlying mechanisms.

Rev Neurol 2020 Dec;71(11):391-398

Universidad de La Laguna, 38320 La Laguna, España.

Introduction: The current evidence collected consistent results about morphological and functional brain changes produced by psychological treatment. Exposure cognitive-behavioral therapy (CBT) is currently the most effective psychological treatment for phobias.

Aims: To explore the brain activation and self-reported changes in patients with specific phobias to small animals who underwent a CBT exposure program and to prove if the CBT program made phobic patients process feared stimuli similarly to non-phobic persons. Read More

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December 2020

Analysis and Biophysics of Surface EMG for Physiotherapists and Kinesiologists: Toward a Common Language With Rehabilitation Engineers.

Front Neurol 2020 15;11:576729. Epub 2020 Oct 15.

Neuromuscular Systems Laboratory, School of Electrical and Electronic Engineering, University College Dublin, Dublin, Ireland.

Recent decades have seen a move toward evidence-based medicine to inform the clinical decision-making process with reproducible findings from high-quality research studies. There is a need for objective, quantitative measurement tools to increase the reliability and reproducibility of studies evaluating the efficacy of healthcare interventions, particularly in the field of physical and rehabilitative medicine. Surface electromyography (sEMG) is a non-invasive measure of muscle activity that is widely used in research but is under-utilized as a clinical tool in rehabilitative medicine. Read More

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October 2020

Functional Brain Networks: Unique Patterns with Hedonic Appetite and Confidence to Resist Eating in Older Adults with Obesity.

Obesity (Silver Spring) 2020 12 1;28(12):2379-2388. Epub 2020 Nov 1.

Section on Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Objective: The purpose of this study was to determine whether baseline measures of hedonic hunger-the Power of Food Scale-and self-control for food consumption-the Weight Efficacy Lifestyle Questionnaire-were associated with network topology within two sets of brain regions (regions of interest [ROIs] 1 and 2) in a group of older adults with obesity. These previously identified brain regions were shown in a different cohort of older adults to be critical for discriminating weight loss success and failure.

Methods: Baseline functional magnetic resonance imaging data (resting state and food cue task) were collected in a novel cohort of 67 older adults with obesity (65-85 years, BMI = 35-42 kg/m ) participating in an 18-month randomized clinical trial on weight regain. Read More

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December 2020

A Content Analysis of U.S. Adults' Open-Ended Responses to E-Cigarette Risk Messages.

Health Commun 2020 Oct 30:1-11. Epub 2020 Oct 30.

School of Public Health, Georgia State University.

To better understand the processing of e-cigarette prevention messages, we conducted a content analysis of 1,968 participants' open-ended responses to one of four messages, which focused on industry manipulation (), financial and psychological cost of vaping (), harmful chemicals in e-cigarettes (), or uncertainty about the ingredients of e-liquids (). Health Belief Model (HBM) and perceived message effectiveness (PME) constructs were coded and the frequency of each variable was compared across message conditions. Among the HBM constructs, perceived health threat had the most mentions overall (38. Read More

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October 2020

Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint.

Pharmacol Ther 2021 Mar 20;219:107709. Epub 2020 Oct 20.

Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA; Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA. Electronic address:

The CD40 receptor and its ligand CD40L is one of the most critical molecular pairs of the stimulatory immune checkpoints. Both CD40 and CD40L have a membrane form and a soluble form generated by proteolytic cleavage or alternative splicing. CD40 and CD40L are widely expressed in various types of cells, among which B cells and myeloid cells constitutively express high levels of CD40, and T cells and platelets express high levels of CD40L upon activation. Read More

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Risk Information Seeking Behavior in Disaster Resettlement: A Case Study of Ankang City, China.

Int J Environ Res Public Health 2020 10 8;17(19). Epub 2020 Oct 8.

School of Public Policy and Administration, Xi'an Jiaotong University, Xi'an 710049, China.

In 2011, the Chinese government launched a disaster mitigation and preparedness program called the Resettlement of South Shaanxi (RSS). Due to the wide geographical scope and complex interests, the possibility of conflicts was increased during and after resettlement. Efficient risk communication improves the supply of information about risks and meets the risk-related information needs of individuals. Read More

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October 2020

The role of social relatedness and self-beliefs in social functioning in first-episode psychosis: Are we overestimating the contribution of illness-related factors?

Eur Psychiatry 2020 10 9;63(1):e92. Epub 2020 Oct 9.

Orygen, Melbourne, Victoria, Australia.

Objective: Numerous research studies have demonstrated an association between higher symptom severity and cognitive impairment with poorer social functioning in first-episode psychosis (FEP). By contrast, the influence of subjective experiences, such as social relatedness and self-beliefs, has received less attention. Consequently, a cohesive understanding of how these variables interact to influence social functioning is lacking. Read More

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October 2020