35 results match your criteria self-disinfecting surfaces

Photocatalytic Treatments for Personal Protective Equipment: Experimental Microbiological Investigations and Perspectives for the Enhancement of Antimicrobial Activity by Micrometric TiO.

Int J Environ Res Public Health 2021 08 16;18(16). Epub 2021 Aug 16.

Department of Movement, Human, and Health Sciences, Laboratory of Epidemiology and Biotechnologies, University of Rome "Foro Italico", 00135 Rome, Italy.

The COVID-19 pandemic has led to countries enforcing the use of facial masks to prevent contagion. However, acquisition, reuse, and disposal of personal protective equipment (PPE) has generated problems, in regard to the safety of individuals and environmental sustainability. Effective strategies to reprocess and disinfect PPE are needed to improve the efficacy and durability of this equipment and to reduce waste load. Read More

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Assessment of Antiviral Coatings for High-Touch Surfaces by Using Human Coronaviruses HCoV-229E and SARS-CoV-2.

Appl Environ Microbiol 2021 09 10;87(19):e0109821. Epub 2021 Sep 10.

Société des Produits Nestlé, Nestlé Research, Institute of Food Safety and Analytical Science, Lausanne, Switzerland.

A novel and robust approach to evaluate the antiviral activity of coatings was developed, assessing three commercially available leave-on surface coating products for efficacy against human coronaviruses (HCoVs) HCoV-229E and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The assessment is based on three criteria that reflect real-life settings, namely, (i) immediate antiviral effect, (ii) effect after repeated cleaning of the coated surface, and (iii) antiviral activity in the presence of organic material. The results showed that only a copper compound-based coating successfully met all three criteria. Read More

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September 2021

Broad-Spectrum Photo-Antimicrobial Polymers Based on Cationic Polystyrene and Rose Bengal.

Front Med (Lausanne) 2021 24;8:641646. Epub 2021 May 24.

Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, Castellón, Spain.

New strategies to fight bacteria and fungi are necessary in view of the problem of iatrogenic and nosocomial infections combined with the growing threat of increased antimicrobial resistance. Recently, our group has prepared and described two new readily available materials based on the combination of Rose Bengal (singlet oxygen photosensitizer) and commercially available cationic polystyrene (macroporous resin Amberlite® IRA 900 or gel-type resin IRA 400). These materials showed high efficacy in the antimicrobial photodynamic inactivation (aPDI) of . Read More

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Rapid and Repetitive Inactivation of SARS-CoV-2 and Human Coronavirus on Self-Disinfecting Anionic Polymers.

Adv Sci (Weinh) 2021 06 8;8(11):e2003503. Epub 2021 Mar 8.

Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, NC, 27695, USA.

While the ongoing COVID-19 pandemic affirms an urgent global need for effective vaccines as second and third infection waves are spreading worldwide and generating new mutant virus strains, it has also revealed the importance of mitigating the transmission of SARS-CoV-2 through the introduction of restrictive social practices. Here, it is demonstrated that an architecturally- and chemically-diverse family of nanostructured anionic polymers yield a rapid and continuous disinfecting alternative to inactivate coronaviruses and prevent their transmission from contact with contaminated surfaces. Operating on a dramatic pH-drop mechanism along the polymer/pathogen interface, polymers of this archetype inactivate the SARS-CoV-2 virus, as well as a human coronavirus surrogate (HCoV-229E), to the minimum detection limit within minutes. Read More

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Antimicrobial TiO nanocomposite coatings for surfaces, dental and orthopaedic implants.

Chem Eng J 2021 Jul 23;416:129071. Epub 2021 Feb 23.

Nanotechnology and Bio-Engineering Research Group, Department of Environmental Science, School of Science, Institute of Technology Sligo, Ash Lane, Sligo, Ireland.

Engineering of self-disinfecting surfaces to constrain the spread of SARS-CoV-2 is a challenging task for the scientific community because the human coronavirus spreads through respiratory droplets. Titania (TiO) nanocomposite antimicrobial coatings is one of the ideal remedies to disinfect pathogens (virus, bacteria, fungi) from common surfaces under light illumination. The photocatalytic disinfection efficiency of recent TiO nanocomposite antimicrobial coatings for surfaces, dental and orthopaedic implants are emphasized in this review. Read More

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Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2.

Viruses 2020 12 24;13(1). Epub 2020 Dec 24.

Department of Microbiology and Immunology, Reno School of Medicine, University of Nevada, 1664 N Virginia Street, Reno, NV 89557, USA.

The newly identified pathogenic human coronavirus, SARS-CoV-2, led to an atypical pneumonia-like severe acute respiratory syndrome (SARS) outbreak called coronavirus disease 2019 (abbreviated as COVID-19). Currently, nearly 77 million cases have been confirmed worldwide with the highest numbers of COVID-19 cases in the United States. Individuals are getting vaccinated with recently approved vaccines, which are highly protective in suppressing COVID-19 symptoms but there will be a long way before the majority of individuals get vaccinated. Read More

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December 2020

Simple Fabrication of Transparent, Colorless, and Self-Disinfecting Polyethylene Terephthalate Film via Cold Plasma Treatment.

Nanomaterials (Basel) 2020 May 15;10(5). Epub 2020 May 15.

Advanced Nano-Surface Department, Korea Institute of Materials Science, Changwon 51508, Korea.

Cross-infection following cross-contamination is a serious social issue worldwide. Pathogens are normally spread by contact with germ-contaminated surfaces. Accordingly, antibacterial surface technologies are urgently needed and have consequently been actively developed in recent years. Read More

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Self-Disinfecting Copper Beds Sustain Terminal Cleaning and Disinfection Effects throughout Patient Care.

Appl Environ Microbiol 2019 12 13;86(1). Epub 2019 Dec 13.

Highpoint Health, Lawrenceburg, Indiana, USA.

Microbial burden associated with near-patient touch surfaces results in a greater risk of health care-associated infections (HAIs). Acute care beds may be a critical fomite, as traditional plastic surfaces harbor the highest concentrations of bacteria associated with high-touch surfaces in a hospital room's patient zone. Five high-touch intensive care unit (ICU) bed surfaces encountered by patients, health care workers, and visitors were monitored by routine culture to assess the effect U. Read More

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December 2019

Potential antimicrobial effects of photocatalytic nanothecnologies in hospital settings.

Ann Ig 2019 Sep-Oct;31(5):461-473

Department of Public Health and Infectious Diseases, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy.

Background: Recently, several advanced technologies have been considered to reduce the microbial load in hospital environments and control Healthcare Associated Infections (HAIs) incidence. New strategies for preventing HAIs have continuously evolved, including enforcement of hygiene procedures by novel liquid biocides or no-touch technologies, self-disinfecting surfaces coated by heavy metals or light-activated photosensitizers such as Titanium Dioxide (TiO2) nanoparticles.

Study Design: Review publications concerning the use of photocatalytic systems in hospital setting, focusing on products based on TiO. Read More

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BODIPY-embedded electrospun materials in antimicrobial photodynamic inactivation.

Photochem Photobiol Sci 2019 Aug 31;18(8):1923-1932. Epub 2019 May 31.

Department of Chemistry, United States Air Force Academy, CO 80840, USA.

Drug-resistant pathogens, particularly those that result in hospital acquired infections (HAIs), have emerged as a critical priority for the World Health Organization. To address the need for self-disinfecting materials to counter the threat posed by the transmission of these pathogens from surfaces to new hosts, here we investigated if a cationic BODIPY photosensitizer, embedded via electrospinning into nylon and polyacrylonitrile (PAN) nanofibers, was capable of inactivating both bacteria and viruses via antimicrobial photodynamic inactivation (aPDI). Materials characterization, including fiber morphology and the degree of photosensitizer loading, was assessed by scanning electron microscopy (SEM), thermal gravimetric analysis (TGA), and UV-visible diffuse reflectance spectroscopy (UV-Vis DRS), and demonstrated that the materials were comprised of nanofibers (125-215 nm avg. Read More

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Continuous room decontamination technologies.

Am J Infect Control 2019 06;47S:A72-A78

Division of Infectious Diseases, Duke University School of Medicine, Durham, NC, USA.

The contaminated surface environment in the rooms of hospitalized patients is an important risk factor for the colonization and infection of patients with multidrug-resistant pathogens. Improved terminal cleaning and disinfection have been demonstrated to reduce the incidence of health care-associated infections. In the United States, hospitals generally perform daily cleaning and disinfection of patient rooms. Read More

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Self-disinfecting surfaces and infection control.

Colloids Surf B Biointerfaces 2019 Jun 16;178:8-21. Epub 2019 Feb 16.

National Institute of Health, Environmental Health Department, Porto, Portugal; EPIUnit - Institute of Public Health, University of Porto, Porto, Portugal.

According to World Health Organization, every year in the European Union, 4 million patients acquire a healthcare associated infection. Even though some microorganisms represent no threat to healthy people, hospitals harbor different levels of immunocompetent individuals, namely patients receiving immunosuppressors, with previous infections, or those with extremes of age (young children and elderly), requiring the implementation of effective control measures. Public spaces have also been found an important source of infectious disease outbreaks due to poor or none infection control measures applied. Read More

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High-Strength Antibacterial Chitosan-Cellulose Nanocrystal Composite Tissue Paper.

Langmuir 2019 01 6;35(1):104-112. Epub 2018 Dec 6.

Department of Forest Biomaterials , NC State University , Campus Box 8005, Raleigh , North Carolina 27695 , United States.

A heightened need to control the spread of infectious diseases prompted the current work in which functionalized and innovative antimicrobial tissue paper was developed with a hydrophobic spray-coating of chitosan (Ch) and cellulose nanocrystals (CNCs) composite. It was hypothesized that the hydrophobic nature of chitosan could be counterbalanced by the addition of CNC to maintain fiber formation and water absorbency. Light-weight tissue handsheets were prepared, spray-coated with Ch, CNC, and their composite coating (ChCNC), and tested for antimicrobial activity against Gram-negative bacteria Escherichia coli and a microbial sample from a human hand after using the rest room. Read More

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January 2019

Polylactic acid sealed polyelectrolyte complex microcontainers for controlled encapsulation and NIR-Laser based release of cargo.

Colloids Surf B Biointerfaces 2019 Jan 10;173:521-528. Epub 2018 Oct 10.

School of Engineering and Materials Science, Queen Mary University of London, Mile End, Eng, 215, London, E1 4NS, United Kingdom; National Research Tomsk Polytechnic University, 634050, Tomsk, Russian Federation. Electronic address:

Surface mediated drug delivery is important for a large variety of applications, especially in medicine to control cell growth, prevent blood platelet activation on implants or for self-disinfecting devices (e.g. catheters). Read More

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January 2019

The efficacy of self-disinfecting bedrail covers in an intensive care unit.

Am J Infect Control 2018 04 20;46(4):417-419. Epub 2017 Nov 20.

Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA.

Background: Hospital surfaces are considered important vectors in the spread of nosocomial pathogens. This study evaluated microbial counts on novel antimicrobial bedrail covers over a 2-week period in a critical care environment.

Methods: Disposable bedrail covers (Aionx Inc, Hershey, PA) made of a copper and silver polymer and capable of conducting an imperceptible surface potential, were installed in a case-control manner on a series of occupied intensive care unit beds. Read More

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Fungicidal activity of copper-sputtered flexible surfaces under dark and actinic light against azole-resistant Candida albicans and Candida glabrata.

J Photochem Photobiol B 2017 Sep 29;174:229-234. Epub 2017 Jul 29.

Department of Fundamental Microbiology, University of Lausanne, Quartier Unil-Sorge, Biophore Building, CH-1015 Lausanne, Switzerland.

Candida spp. are able to survive on hospital surfaces and causes healthcare-associated infections (HCAIs). Since surface cleaning and disinfecting interventions are not totally effective to eliminate Candida spp. Read More

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September 2017

Self-disinfecting surfaces and activity against Staphyloccocus aureus ATCC 6538 under real-life conditions.

J Hosp Infect 2017 Oct 22;97(2):196-199. Epub 2017 Jun 22.

Division of Hygiene and Medical Microbiology, Department of Hygiene, Microbiology and Public Health, Medical University of Innsbruck, Innsbruck, Austria; Christian Doppler Laboratory for Invasive Fungal Infections, Innsbruck, Austria. Electronic address:

Environmental surface contamination provides a potential reservoir for pathogens to cause infections. As such, self-disinfecting surfaces have been developed to possibly reduce exogenous transmission. Five different self-disinfecting surfaces were evaluated for activity against Staphylococcus aureus ATCC 6538 under real-life conditions using the dry inoculation method. Read More

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October 2017

Pre-post evaluation of effects of a titanium dioxide coating on environmental contamination of an intensive care unit: the TITANIC study.

J Hosp Infect 2018 Jul 15;99(3):256-262. Epub 2017 Apr 15.

Department of Intensive Care, Gelderse Vallei Hospital, Ede, The Netherlands. Electronic address:

Background: Among patients admitted to European hospitals or intensive care units (ICUs), 5.7% and 19.5% will encounter healthcare-associated infections (HAIs), respectively, and antimicrobial resistance is emerging. Read More

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Reduced health care-associated infections in an acute care community hospital using a combination of self-disinfecting copper-impregnated composite hard surfaces and linens.

Am J Infect Control 2016 12 28;44(12):1565-1571. Epub 2016 Sep 28.

Office of Hospital Epidemiology/Infection Prevention & Control, University of Virginia Health System, Charlottesville, VA; Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Virginia Health System, Charlottesville, VA.

Background: The purpose of this study was to determine the effectiveness of copper-impregnated composite hard surfaces and linens in an acute care hospital to reduce health care-associated infections (HAIs).

Methods: We performed a quasiexperimental study with a control group, assessing development of HAIs due to multidrug resistant organisms (MDROs) and Clostridium difficile in the acute care units of a community hospital following the replacement of a 1970s-era clinical wing with a new wing outfitted with copper-impregnated composite hard surfaces and linens.

Results: The study was conducted over a 25. Read More

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December 2016

'No touch' technologies for environmental decontamination: focus on ultraviolet devices and hydrogen peroxide systems.

Curr Opin Infect Dis 2016 08;29(4):424-31

aDepartment of Hospital Epidemiology, University of North Carolina Health Care bDivision of Infectious Diseases, UNC School of Medicine, Chapel Hill, North Carolina, USA.

Purpose Of Review: This article reviews 'no touch' methods for disinfection of the contaminated surface environment of hospitalized patients' rooms. The focus is on studies that assessed the effectiveness of ultraviolet (UV) light devices, hydrogen peroxide systems, and self-disinfecting surfaces to reduce healthcare-associated infections (HAIs).

Recent Findings: The contaminated surface environment in hospitals plays an important role in the transmission of several key nosocomial pathogens including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp. Read More

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Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals.

John M Boyce

Antimicrob Resist Infect Control 2016 11;5:10. Epub 2016 Apr 11.

J.M. Boyce Consulting, LLC, 62 Sonoma Lane, Middletown, CT 06457 USA.

Experts agree that careful cleaning and disinfection of environmental surfaces are essential elements of effective infection prevention programs. However, traditional manual cleaning and disinfection practices in hospitals are often suboptimal. This is often due in part to a variety of personnel issues that many Environmental Services departments encounter. Read More

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Selective Inactivation of Resistant Gram-Positive Pathogens with a Light-Driven Hybrid Nanomaterial.

ACS Appl Mater Interfaces 2015 Sep 11;7(37):20965-71. Epub 2015 Sep 11.

Westfälische Wilhelms-Universität Münster , Physikalisches Institut - Center for Nanotechnology, Heisenbergstrasse 11, 48149 Münster, Germany.

Herein, we present a straightforward strategy to disperse highly insoluble photosensitizers in aqueous environments, without major synthetic efforts and keeping their photosensitizing abilities unaffected. A layered nanoclay was employed to adsorb and to solubilize a highly efficient yet hydrophobic Si(IV) phthalocyaninate in water. The aggregation of the photoactive dye was correlated with its photophysical properties, particularly with the ability to produce highly cytotoxic singlet oxygen. Read More

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September 2015

Cleaning Hospital Room Surfaces to Prevent Health Care-Associated Infections: A Technical Brief.

Ann Intern Med 2015 Oct 11;163(8):598-607. Epub 2015 Aug 11.

The cleaning of hard surfaces in hospital rooms is critical for reducing health care-associated infections. This review describes the evidence examining current methods of cleaning, disinfecting, and monitoring cleanliness of patient rooms, as well as contextual factors that may affect implementation and effectiveness. Key informants were interviewed, and a systematic search for publications since 1990 was done with the use of several bibliographic and gray literature resources. Read More

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October 2015

Comparison of Infectious Agents Susceptibility to Photocatalytic Effects of Nanosized Titanium and Zinc Oxides: A Practical Approach.

Nanoscale Res Lett 2015 Dec 4;10(1):1023. Epub 2015 Aug 4.

Department of Food Hygiene and Public Health Protection Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159, 02-776, Warsaw, Poland,

Nanotechnology contributes towards a more effective eradication of pathogens that have emerged in hospitals, veterinary clinics, and food processing plants and that are resistant to traditional drugs or disinfectants. Since new methods of pathogens eradication must be invented and implemented, nanotechnology seems to have become the response to that acute need. A remarkable achievement in this field of science was the creation of self-disinfecting surfaces that base on advanced oxidation processes (AOPs). Read More

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December 2015

Chances and limitations of nanosized titanium dioxide practical application in view of its physicochemical properties.

Nanoscale Res Lett 2015 11;10:57. Epub 2015 Feb 11.

Department of Food Hygiene and Public Health Protection, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland.

Nanotechnology is a field of science that is nowadays developing in a dynamic way. It seems to offer almost endless opportunities of contribution to many areas of economy and human activity, in general. Thanks to nanotechnology, the so-called nanomaterials can be designed. Read More

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A review of heterogeneous photocatalysis for water and surface disinfection.

Molecules 2015 Mar 30;20(4):5574-615. Epub 2015 Mar 30.

Nanotechnology and Integrated BioEngineering Centre, Ulster University, Newtownabbey, Northern Ireland BT37 0QB, UK.

Photo-excitation of certain semiconductors can lead to the production of reactive oxygen species that can inactivate microorganisms. The mechanisms involved are reviewed, along with two important applications. The first is the use of photocatalysis to enhance the solar disinfection of water. Read More

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Long-term efficacy of a self-disinfecting coating in an intensive care unit.

Am J Infect Control 2014 Nov 30;42(11):1178-81. Epub 2014 Oct 30.

Department of Soil, Water, and Environmental Science, University of Arizona, Tucson, AZ. Electronic address:

Background: Cleaning and disinfecting fomites can effectively remove/kill pathogens on surfaces, but studies have shown that more than one-half the time, surfaces are not adequately cleaned or are recontaminated within minutes. This study evaluated a product designed to create a long-lasting surface coating that provides continuous disinfecting action.

Methods: This study was performed in an intensive care unit (ICU) in a major hospital. Read More

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November 2014

Self-disinfecting and microbiocide-impregnated surfaces and fabrics: what potential in interrupting the spread of healthcare-associated infection?

Hilary Humphreys

Clin Infect Dis 2014 Mar 21;58(6):848-53. Epub 2013 Nov 21.

Department of Clinical Microbiology, The Royal College of Surgeons in Ireland.

Innovative technologies have identified approaches to developing self-disinfecting surfaces or fabrics to minimize healthcare-associated infection (HCAI). These include altering the structure or surface to minimize the attachment of microbes or to delay the development of biofilm, using compounds that are activated in the presence of light to reduce the microbial burden, and incorporating a heavy metal such as silver or copper with intrinsic antimicrobial activity. Most technologies for surfaces and fabrics have been assessed in vitro and have been shown to reduce bacterial numbers by ≥2 logs. Read More

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The role of the surface environment in healthcare-associated infections.

Curr Opin Infect Dis 2013 Aug;26(4):338-44

Department of Hospital Epidemiology, University of North Carolina Healthcare, UNC School of Medicine, Chapel Hill, North Carolina 27599-7030, USA.

Purpose Of Review: This article reviews the evidence demonstrating the importance of contamination of hospital surfaces in the transmission of healthcare-associated pathogens and interventions scientifically demonstrated to reduce the levels of microbial contamination and decrease healthcare-associated infections.

Recent Findings: The contaminated surface environment in hospitals plays an important role in the transmission of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp. (VRE), Clostridium difficile, Acinetobacter spp. Read More

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