37,578 results match your criteria selenium

A MoSe/N-doped hollow carbon sphere host for rechargeable Na-Se batteries.

Dalton Trans 2021 May 13. Epub 2021 May 13.

Department of Chemistry, Northeast Normal University, 5268 Renming Street, Changchun, China.

Sodium-selenium (Na-Se) batteries are promising alternatives to lithium-ion batteries for energy storage systems owing to their high energy density and natural abundance of Na resources. However, their drawbacks of low Se loading, dissolution of intermediate sodium polyselenides in the electrolyte and volumetric expansion of Se impede their real applications. To address these issues, herein, we report a multifunctional Se host with MoSe2 nanosheets coupled with nitrogen-doped porous carbon hollow spheres for the first time. Read More

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Selenium Status Affects Hypertrophic Growth of Skeletal Muscle in Growing Zebrafish by Mediating Protein Turnover.

J Nutr 2021 May 12. Epub 2021 May 12.

College of Fisheries, Huazhong Agricultural University, Wuhan, China.

Background: Selenium (Se) status is closely related to skeletal muscle physiological status. However, its influence on skeletal muscle growth has not been well studied.

Objectives: This study aimed to analyze the impacts of overall Se status (deficient, adequate, and high) on skeletal muscle growth using a growing zebrafish model. Read More

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The Role of Nutrition in COVID-19 Susceptibility and Severity of Disease: A Systematic Review.

J Nutr 2021 May 12. Epub 2021 May 12.

Medical Research Council (MRC) Unit The Gambia at the London School of Hygiene & Tropical Medicine, Fajara, The Gambia.

Background: Many nutrients have powerful immunomodulatory actions with the potential to alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to symptoms, likelihood of severe disease, and survival.

Objective: The aim was to review the latest evidence on how malnutrition across all its forms (under- and overnutrition and micronutrient status) may influence both susceptibility to, and progression of, COVID-19.

Methods: We synthesized information on 13 nutrition-related components and their potential interactions with COVID-19: overweight, obesity, and diabetes; protein-energy malnutrition; anemia; vitamins A, C, D, and E; PUFAs; iron; selenium; zinc; antioxidants; and nutritional support. Read More

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Synthesis of Nanocomposites of V₂O©Selenium Nanoparticles and Multiwalled Carbon Nanotubes for Antimicrobial Activity.

J Nanosci Nanotechnol 2021 Nov;21(11):5673-5680

P.G. and Research Department of Chemistry, Bishop Heber College (Autonomous), Tiruchirappalli 620017, Tamilnadu, India.

The authors report the preparation of the nanocomposite comprising of vanadium pentoxide (V₂O) and selenium (Se) nanoparticles and functionalized multiwalled carbon nanotubes (MWCNTs) (V₂O@Se NPs/MWCNTs). Since Se NPs possesses extraordinary physicochemical properties including larger surface area with higher adsorption capacity, V₂O NPs were adsorbed onto Se NPs surface through physisorption process (designated as V₂O@Se NPs). The nanocomposite synthesized hydrothermally was evaluated for its antimicrobial activity. Read More

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November 2021

A Review of the Antimicrobial Activity of Selenium Nanoparticles.

J Nanosci Nanotechnol 2021 Nov;21(11):5383-5398

Instituto de Investigación en Biociencias, Centro Universitario de Los Altos, Universidad de Guadalajara, Tepatitlán de Morelos, Jalisco, 47600, México.

Antimicrobial resistance has become a severe problem for health systems worldwide, and counteractions are challenging because of the lack of interest of pharmaceutical companies in generating new and effective antimicrobial drugs. Selenium nanoparticles have attracted considerable interest in treating bacteria, fungi, parasites, and viruses of clinical importance due to their high therapeutic efficacy and almost zero generation of adverse effects. Some studies have revealed that the antimicrobial activity of these nanoparticles is due to the generation of reactive oxygen species, but more studies are needed to clarify their antimicrobial mechanisms. Read More

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November 2021

Nanomedicine for acute respiratory distress syndrome: The latest application, targeting strategy, and rational design.

Acta Pharm Sin B 2021 May 7. Epub 2021 May 7.

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.

Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation and destruction of the lung air-blood barrier, leading to irreversible and substantial respiratory function damage. Patients with coronavirus disease 2019 (COVID-19) have been encountered with a high risk of ARDS, underscoring the urgency for exploiting effective therapy. However, proper medications for ARDS are still lacking due to poor pharmacokinetics, non-specific side effects, inability to surmount pulmonary barrier, and inadequate management of heterogeneity. Read More

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Revisiting the problem of crystallisation and melting of Selenium.

J Phys Condens Matter 2021 May 11. Epub 2021 May 11.

Department of Condensed Matter Physics and Materials Science, Tata Institute of Fundamental Research, Tifr, Homi Bhabha Road, Mumbai, Mumbai, Maharashtra, 400005, INDIA.

The presence of a unique melting point is associated with crystals and not glasses. The boundary between an imperfect crystal ( laden with defects ) which still possess a well defined melting temperature and a glass is not a well defined one. To convert a crystal to a glass, one needs to introduce a large density of defects in a manner that it destroys the long range order in the system but preserves its structural integrity. Read More

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Associations between blood heavy metal(loid)s and serum heme oxygenase-1 in pregnant women: Do their distribution patterns matter?

Environ Pollut 2021 Apr 29;286:117249. Epub 2021 Apr 29.

Institute of Reproductive and Child Health, Peking University/ Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Beijing, 100191, PR China; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, PR China.

The relationship between heavy metal(loid)s exposure and oxidative stress damage is a matter of research interest. Our study aimed to investigate the distribution patterns of the nine heavy metal(loid)s in blood of pregnant women, including four toxic heavy metal(loid)s [arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg)] and five typical heavy metal(loid)s [manganese (Mn), cobalt (Co), copper (Cu), zinc (Zn), and selenium (Se)] in blood. Blood samples of 348 women were collected and their concentrations in the serum (sr) and blood cells (bc) were measured, as well as serum heme oxygenase-1 (HO-1) (an oxidative stress marker). Read More

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Selenium nanoparticles ameliorate Brassica napus L. cadmium toxicity by inhibiting the respiratory burst and scavenging reactive oxygen species.

J Hazard Mater 2021 Apr 16;417:125900. Epub 2021 Apr 16.

Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Qingdao 266237, China. Electronic address:

Cadmium (Cd) is a widely distributed soil contaminant which induces oxidative damage and is therefore toxic to plants. Although selenium oxyanions such as selenite (SeO) and selenate (SeO) can alleviate Cd stress to plants, it is not known whether selenium nanoparticles (SeNPs) are able to do the same. The present study demonstrated the positive impact of both SeNPs and SeO on Brassica napus L. Read More

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Mechanical Insights into Thiol-Mediated Synergetic Biotransformation of Cadmium and Selenium in Nematodes.

Environ Sci Technol 2021 May 11. Epub 2021 May 11.

CAS Key Laboratory of Urban Pollutant Conversion, Department of Applied Chemistry, University of Science and Technology of China, Hefei 230026, China.

Cadmium ion (Cd) is a common environmental pollutant with high biotoxicity. Interestingly, the Cd biotoxicity can be alleviated by the coexisting selenite (SeO), which induces the formation of cadmium selenide-rich nanoparticles (CdSe NPs) under the function of thiol-capping peptides. However, the detailed biochemical mechanisms by which Cd and Se are synergistically transformed into CdSe NPs in living organisms remain unclear so far. Read More

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Impacts of an egg intervention on nutrient adequacy among young Malawian children.

Matern Child Nutr 2021 May 11:e13196. Epub 2021 May 11.

Department of Nutrition, University of California, Davis, Davis, California, USA.

Eggs are a rich source of multiple nutrients that support child growth and development. Provision of eggs as a complementary food may improve dietary adequacy among young children at risk for undernutrition. Our objective was to test the impact of an egg intervention on the adequacy of total nutrient intakes and micronutrient density among 6- to 15-month-old Malawian children. Read More

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Nutrition and Immunity in COVID-19.

Adv Exp Med Biol 2021 ;1318:485-497

Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Nutrition can strongly influence infection trajectories by either boosting or suppressing the immune system. During the recently emerged pandemic of coronavirus disease 2019 (COVID-19), individuals who possess diets high in fat, refined carbohydrates, and sugars have shown to be highly prone to the disease and associated adverse outcomes. Both micronutrients and macronutrients provide benefits at different stages of the infection. Read More

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The effects of the exposure to neurotoxic elements on Italian schoolchildren behavior.

Sci Rep 2021 May 10;11(1):9898. Epub 2021 May 10.

Department of Occupational Health, University of Brescia, Piazzale Spedali Civili, 1, 25123, Brescia, BS, Italy.

Neurodevelopmental disorders are constantly increasing on a global scale. Some elements like heavy metals are known to be neurotoxic. In this cross-sectional study we assessed the neurobehavioral effect of the exposure to trace elements including lead, mercury, cadmium, manganese, arsenic and selenium and their interactions among 299 schoolchildren residing in the heavily polluted Taranto area in Italy. Read More

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Natural antioxidants enhance the power of physical and mental activities versus risk factors inducing progression of Alzheimer's disease in rats.

Int Immunopharmacol 2021 May 7;96:107729. Epub 2021 May 7.

Pharmacology and Toxicology Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. Electronic address:

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease that is exacerbated by social isolation (SI) and protein malnutrition (PM). Antioxidants, physical and mental activities (Ph&M) can maintain cognitive functions and protect against dementia.

Objective: To investigate the impact of Epigallocatechin-3-gallate (EGCG), Vitamin E (VE), Vitamin C (VC), and Selenium (Se), in enhancing the potential effect of Ph&M versus SI&PM as risk factors in the progression of AD in rats. Read More

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Transgenerational effects of selenomethionine on behaviour, social cognition, and the expression of genes in the serotonergic pathway in zebrafish.

Environ Pollut 2021 May 3;286:117289. Epub 2021 May 3.

Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, Saskatchewan, S7N 5E2, Canada; Toxicology Centre, University of Saskatchewan, 44 Campus Drive, Saskatoon, Saskatchewan, S7N 5B3, Canada.

Elevated levels of contaminants from human activities have become a major threat to animals, particularly within aquatic ecosystems. Selenium (Se) is a naturally occurring element with a narrow range of safe intake, but excessive Se has toxicological effects, as it can bioaccumulate and cause cognitive and behavioural impairments. In this study, we investigated whether exposure to Se would also have transgenerational effects, causing changes in the descendants of exposed individuals. Read More

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Surface Selenylation Engineering for Construction of a Hierarchical NiSe/Carbon Nanorod: A High-Performance Nonenzymatic Glucose Sensor.

ACS Appl Mater Interfaces 2021 May 10. Epub 2021 May 10.

College of Food Science and Engineering, Northwest A&F University, Yangling, 712100 Xianyang, Shaanxi, China.

As glucose (Glu) is an essential substance for metabolism as well as a symbol to diagnose diabetes, the demand of Glu sensors has increased significantly in recent decades. In this work, a hierarchical Ni-based electrochemical enzyme-free Glu sensor, namely, NiSe/CNR (carbon nanorod), was engineered through a facile thermal treatment using dimethylglyoxime dinickel salt with selenium (Se) powder. The prepared NiSe/CNR not only subtly introduces a hierarchical structure with rod-like carbon nanorods and rock-like NiSe nanoparticles, which are extremely helpful in offering a greater catalytic activity area and more catalytic active sites, but also incorporates the Se element to increase the inherent activity. Read More

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Selenium Defect Boosted Electrochemical Performance of Binder-Free VSe Nanosheets for Aqueous Zinc-Ion Batteries.

ACS Appl Mater Interfaces 2021 May 10. Epub 2021 May 10.

School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China.

As a typical transition-metal dichalcogenides, vanadium diselenide (VSe) is a promising electrode material for aqueous zinc-ion batteries due to its metallic characteristics and excellent electronic conductivity. In this work, we propose a strategy of hydrothermal reduction synthesis of stainless-steel (SS)-supported VSe nanosheets with defect (VSe-SS), thereby further improving the conductivity and activity of VSe-SS. Density functional theory calculations confirmed that Se defect can adjust the adsorption energy of Zn ions. Read More

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The rationale for selenium supplementation in patients with autoimmune thyroiditis, according to the current state of knowledge.

Endokrynol Pol 2021 ;72(2):153-162

Department of Endocrinology, Metabolism, and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.

Selenium (Se) supplements are commonly prescribed to autoimmune thyroiditis (AIT) patients by European endocrinologists, despite the lack of official guidelines. The majority of Europe is depleted of natural Se sources, and the daily population intake does not comply with recommended values. Optimal individual plasma Se concentration is reached when the selenoproteins (selenoprotein P, glutathione peroxidase) are fully saturated. Read More

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January 2021

Selenium speciation and bioavailability from mine discharge to the environment: a field study in Northern Quebec, Canada.

Environ Sci Pollut Res Int 2021 May 10. Epub 2021 May 10.

Centre Eau, Terre et Environnement, Institut national de la recherche scientifique, Université du Québec, 490 rue de la Couronne, Québec, G1K 9A9, Canada.

The speciation, behaviour, and bioavailability of released selenium (Se) from mine effluent discharge to sediments and plants were assessed. Discharged mine effluent containing 65±0.9 μg/L of total Se subsequently contaminated the exposed sediment with an average total Se concentration of 321 mg/kg as well as exposed Typha latifolia plants where 534 and 92 mg/kg were found in roots and leaves, respectively. Read More

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Recent Advances in Living Cationic Polymerization with Emerging Initiation/Controlling Systems.

Macromol Rapid Commun 2021 May 10:e2100148. Epub 2021 May 10.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China.

While the conventional living cationic polymerization (LCP) provided opportunities to synthesizing well-defined polymers with predetermined molecular weights, desirable chemical structures and narrow dispersity, it is still important to continuously innovate new synthetic methods to meet the increasing requirements in advanced material engineering. Consequently, a variety of novel initiation/controlling systems have be demonstrated recently, which have enabled LCP with spatiotemporal control, broadened scopes of monomers and terminals, more user-friendly operations and reaction conditions, as well as improved thermomechanical properties for obtained polymers. In this work, recent advances in LCP is summarized with emerging initiation/controlling systems, including chemical-initiated/controlled cationic reversible addition-fragmentation chain transfer (RAFT) polymerization, photoinitiated/controlled LCP, electrochemical-controlled LCP, thionyl/selenium halide-initiated LCP, organic acid-assisted LCP, and stereoselective LCP. Read More

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Starch/tea polyphenols nanofibrous films for food packaging application: From facile construction to enhance mechanical, antioxidant and hydrophobic properties.

Food Chem 2021 Apr 22;360:129922. Epub 2021 Apr 22.

National R&D Center for Se-rich Agricultural Products Processing, Hubei Engineering Research Center for Deep Processing of Green Se-rich Agricultural Products, School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, PR China.

Starch based food packaging has been receiving increasing attention. However, the inherent poor properties of starch restrict its practical applications in the versatile material science field. In this study, a fast, simple, and environmentally friendly route to construct polyfunctional starch/tea polyphenols nanofibrous films (STNFs) by one-step temperature-assisted electrospinning was developed. Read More

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Micronutrient status influences clinical outcomes of paediatric cancer patients during treatment: A prospective cohort study.

Clin Nutr 2021 Mar 20;40(5):2923-2935. Epub 2021 Mar 20.

Child Life and Health, University of Edinburgh, Edinburgh, EH9 1UW, UK; Department of Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, EH9 1LF, UK.

Background: Research reporting plasma micronutrient status and its impact on clinical outcomes in paediatric cancer is scarce. Therefore, we investigated the prevalence of plasma micronutrient abnormalities and their impact on clinical outcomes and treatment complications.

Methods: A multicentre prospective-cohort study of children aged <18 years diagnosed with cancer was performed between Aug 2010-Jan 2014. Read More

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Interaction of prenatal bisphenols, maternal nutrients, and toxic metal exposures on neurodevelopment of 2-year-olds in the APrON cohort.

Environ Int 2021 May 4;155:106601. Epub 2021 May 4.

Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Canada; Science for Life Laboratory, Department of Environmental Sciences, Stockholm University, Stockholm, Sweden. Electronic address:

Background: Epidemiological studies suggest that Bisphenol-A (BPA) is a developmental neurotoxicant, but the modifying effects of maternal nutrient status or neurotoxicant metal co-exposures have not been reported. Bisphenol-S (BPS) is being used as a BPA-alternative, but few epidemiological studies have evaluated its effects.

Objectives: To examine if prenatal maternal BPA or BPS exposure are associated with children's neurodevelopment at two years of age while adjusting for effect-measure modification by sex, maternal nutrients, and co-exposure to neurotoxic metals. Read More

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Roles of selenium in mineral plant nutrition: ROS scavenging responses against abiotic stresses.

Plant Physiol Biochem 2021 Apr 29;164:27-43. Epub 2021 Apr 29.

Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), Rua Domingos da Costa Lopes 780, Postal Code 17602-496, Tupã, SP, Brazil. Electronic address:

Agronomic biofortification of crops with selenium (Se) is an important strategy to minimize hidden hunger and increase nutrient intake in poor populations. Selenium is an element that has several physiological and biochemical characteristics, such as the mitigation of different types of abiotic stress. Selenoproteins act as powerful antioxidants in plant metabolism through the glutathione peroxidase (GSH) pathway, and provide an increased activity for enzymatic (SOD, CAT, and APX) and non-enzymatic (ascorbic acid, flavonoids, and tocopherols) compounds that act in reactive oxygen species (ROS) scavenging system and cell detoxification. Read More

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Adamantyl Isothiocyanates as Mutant p53 Rescuing Agents and Their Structure-Activity Relationships.

J Med Chem 2021 May 7. Epub 2021 May 7.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C. 20007, United States.

Mutant p53 rescue by small molecules is a promising therapeutic strategy. In this structure-activity relationship study, we examined a series of adamantyl isothiocyanates (Ad-ITCs) to discover novel agents as therapeutics by targeting mutant p53. We demonstrated that the alkyl chain connecting adamantane and ITC is a crucial determinant for Ad-ITC inhibitory potency. Read More

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1,3-Bis(tricyanoborane)imidazoline-2-ylidenate Anion - A Ditopic Dianionic N-Heterocyclic Carbene Ligand.

Angew Chem Int Ed Engl 2021 May 7. Epub 2021 May 7.

Julius-Maximilians-Universitaet Wuerzburg, Institut fuer Anorganische Chemie, Am Hubland, 97074, Wuerzburg, GERMANY.

The 1,3-bis(tricyanoborane)imidazolate anion  1  w as ob-tain-ed in high yield from lithium imidazolate and B(CN) 3 -pyridine adduct .   Anion  1  is chemically very robust and thus allowed the iso-la-t-ion of the corres-ponding H 5 O 2 +  salt. Furthermore, monoanion  1  served as starting species for the  novel dianionic N-heterocyclic carbene, 1,3-bis-(tricyanoborane)-imidazoline-2-ylidenate anion  3  that acts as ditopic ligand via the carbene center and the cyano groups at boron. Read More

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Seed 'primeomics': plants memorize their germination under stress.

Biol Rev Camb Philos Soc 2021 May 7. Epub 2021 May 7.

Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Mumbai, 400085, India.

Seed priming is a pre-germination treatment administered through various chemical, physical and biological agents, which induce mild stress during the early phases of germination. Priming facilitates synchronized seed germination, better seedling establishment, improved plant growth and enhanced yield, especially in stressful environments. In parallel, the phenomenon of 'stress memory' in which exposure to a sub-lethal stress leads to better responses to future or recurring lethal stresses has gained widespread attention in recent years. Read More

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Associations between essential microelements exposure and the aggressive clinicopathologic characteristics of papillary thyroid cancer.

Biometals 2021 May 7. Epub 2021 May 7.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, 230032, Anhui, China.

Aim of this study was to evaluate the association between multiple essential microelements exposure and the aggressive clinicopathologic characteristics of papillary thyroid carcinoma (PTC). The concentrations of 10 essential microelements in urine [cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), molybdenum (Mo), selenium (Se), strontium (Sr), zinc (Zn), and iodine (I)] were measured in 608 patients newly diagnosed with PTC, including 154 males and 454 females. Chi square test and Wilcoxon rank sum test were used to compare general characteristics among males and females. Read More

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Environmental and human iodine and selenium status: lessons from Gilgit-Baltistan, North-East Pakistan.

Environ Geochem Health 2021 May 7. Epub 2021 May 7.

Division of Agricultural and Environmental Sciences, School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, Leicestershire, UK.

Iodine and selenium deficiencies are common worldwide. We assessed the iodine and selenium status of Gilgit-Baltistan, Pakistan. We determined the elemental composition (ICP-MS) of locally grown crops (n = 281), drinking water (n = 82), urine (n = 451) and salt (n = 76), correcting urinary analytes for hydration (creatinine, specific gravity). Read More

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Principles responsible for trace element concentrations in chronic kidney disease.

Clin Nephrol 2021 May 7. Epub 2021 May 7.

Derangements of trace elements often occur in patients with renal failure and play a crucial role in chronic kidney disease. The natural history of trace element deposition with worsening chronic kidney disease has been poorly described. Some essential trace elements may get wasted (e. Read More

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