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Neurochirurgie 2021 Apr 9. Epub 2021 Apr 9.

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China. Electronic address:

Introduction: When the culprit vessel in hemifacial spasm (HFS) is hard to determine, this is a challenge in microvascular decompression (MVD) surgery. In such a situation, small arteries such as perforators to the brainstem might be suspected. But small arteries are omnipresent near the facial nerve root exit/entry zone (fREZ). Read More

Plant Dis 2021 Apr 9. Epub 2021 Apr 9.

Zhaotong Apple Industry Development Center, Zhaotong, China;

More than 30 viral and subviral pathogens infect apple (Malus domestica, an important fruit crop in China) trees and rootstocks, posing a threat to its production. With advances in diagnostic technologies, new viruses including apple rubbery wood virus 1 (ARWV-1), apple rubbery wood virus 2 (ARWV-2), apple luteovirus 1 (ALV), and citrus virus A (CiVA) have been detected (Beatriz et al. 2018; Rott et al. Read More

Am J Physiol Renal Physiol 2021 Apr 5. Epub 2021 Apr 5.

Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Denmark.

The kidneys play a crucial role in maintaining calcium (Ca) and magnesium (Mg) homeostasis by regulating these minerals' reabsorption. In the thick ascending limb of Henle's loop (TAL), Ca and Mg are reabsorbed through the tight junctions by a shared paracellular pathway formed by claudin-16 and claudin-19. Hypercalcemia activates the Ca-sensing receptor (CaSR) in the TAL, causing upregulation of the pore-blocking claudin-14 (CLDN14) that reduces Ca and Mg reabsorption from this segment. Read More

PeerJ Comput Sci 2021 22;7:e368. Epub 2021 Feb 22.

School of Electrical Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, India.

The pandemic of Coronavirus Disease-19 (COVID-19) has spread around the world, causing an existential health crisis. Automated detection of COVID-19 infections in the lungs from Computed Tomography (CT) images offers huge potential in tackling the problem of slow detection and augments the conventional diagnostic procedures. However, segmenting COVID-19 from CT Scans is problematic, due to high variations in the types of infections and low contrast between healthy and infected tissues. Read More

Microorganisms 2021 Mar 21;9(3). Epub 2021 Mar 21.

Infectious Diseases Department, Center of Rickettsiosis and Arthropod-Borne Diseases (CRETAV), San Pedro University Hospital-Center of Biomedical Research from La Rioja (CIBIR), Piqueras, 98, 26006 Logroño, La Rioja, Spain.

Crimean-Congo hemorrhagic fever virus (CCHFV) is an arthropod-borne virus (arbovirus), mainly transmitted by ticks, belonging to the genus (family , order ). CCHFV causes a potentially severe, or even fatal, human disease, and it is widely distributed in Africa, Asia, eastern Europe and, more recently, in South-western Europe. Until a few years ago, no cases of Crimean-Congo hemorrhagic fever (CCHF) had been reported in western Europe, with the exception of several travel-associated cases. Read More

BMJ Case Rep 2021 Apr 1;14(4). Epub 2021 Apr 1.

Department of Vascular Surgery, The Princess Alexandra Hospital, Harlow, UK.

A 77-year-old male patient presented with a 5-day history of abdominal pain, coffee ground vomiting and blood-stained diarrhoea. CT scan of the abdomen and pelvis demonstrated a long segment thrombotic occlusion of the superior mesenteric vein (SMV) extending up to the proximal portion of the portal vein causing significant acute small bowel ischaemia. Patient's deteriorating clinical condition warranted surgical management. Read More

Rev Cardiovasc Med 2021 03;22(1):83-95

Department of Medicine, Cleveland Clinic Foundation, Cleveland, OH 44111, USA.

The coronavirus disease-19 (COVID-19) pandemic has forced hospitals to prioritize COVID-19 patients, restrict resources, and cancel all non-urgent elective cardiac procedures. Clinical visits have only been facilitated for emergency purposes. Fewer patients have been admitted to the hospital for both ST-segment elevation myocardial infarctions (STEMI) and non-ST segment elevation myocardial infarctions (NSTEMI) and a profound decrease in heart failure services has been reported. Read More

Thyroid 2021 Mar 27. Epub 2021 Mar 27.

Vanderbilt University, 5718, Molecular Physiology and Biophysics, Nashville, Tennessee, United States;

Background: The sodium/iodide symporter (NIS) mediates active transport of iodide (I) into the thyroid gland. Mutations in the SLC5A5 gene, which encodes NIS, cause I transport defects (ITDs)-which, if left untreated, lead to congenital hypothyroidism and consequent cognitive and developmental deficiencies. The ITD-causing NIS mutation Y348D, located in transmembrane segment (TMS) 9, was reported in three Sudanese patients. Read More

BMC Cardiovasc Disord 2021 Mar 23;21(1):147. Epub 2021 Mar 23.

Department of Cardiology, Bern University Hospital Inselspital, University of Bern, 3010, Bern, Switzerland.

Background: The recreational drugs cannabis and nitrous oxide (NO) are known for pro-atherogenic effects and are associated with an elevated risk of myocardial infarction. These cardiovascular effects might be underestimated by the public. Culprit-lesion composition of myocardial infarctions associated with cannabis and NO has been unknown so far. Read More

Plant Dis 2021 Mar 23. Epub 2021 Mar 23.

Anhui Agricultural University, 12486, Biosecurity, Hefei, Anhui, China;

(Bunge) A. DC. is a dense, rounded, deciduous shrub commonly planted in landscapes. Read More

J Xray Sci Technol 2021 Mar 15. Epub 2021 Mar 15.

Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, Nanjing, China.

Background: CT-derived fractional flow reserve (FFRCT) and diagnostic accuracy rely on good image quality during coronary CT angiography (CCTA).

Objective: To investigate whether heart rate (HR) and coronary artery calcium (CAC) score decrease image quality and diagnostic performance of two advanced CT scanners including 96-row detector dual source CT (DSCT) and 256-row multidetector CT (MDCT).

Methods: First, 79 patients who underwent CCTA (42 with DSCT and 37 with MDCT) and invasive coronary angiography (ICA) are enrolled. Read More

J Environ Manage 2021 Jun 16;287:112355. Epub 2021 Mar 16.

School of Civil Engineering, Southeast University, Nanjing, 210096, China.

In the sediment-water system of storm sewers (e.g., sediments, interstitial water, and the water column), the migration of nitrogen and its biological transformation with different dissolved oxygen conditions were investigated. Read More

Ocul Immunol Inflamm 2021 Mar 18:1-13. Epub 2021 Mar 18.

Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Chemical injuries can potentially lead to the necrosis anterior segment of the eye, and cornea in particular. Inflammatory cytokines are the first factors produced after chemical ocular injuries. Inflammation via promoting the angiogenesis factor tries to implement the wound healing mechanism in the epithelial and stromal layer of the cornea. Read More

Biologia (Bratisl) 2021 Mar 12:1-10. Epub 2021 Mar 12.

Unité de Recherche UR17ES30 "Génomique Biotechnologie et Stratégies Antivirales" (ViroBiotech), Institut Supérieur de Biotechnologie, Université de Monastir, BP74, Avenue Tahar Hadded, Monastir, 5000 Tunisia.

Influenza A/H1N1 is widely considered to be a very evolutionary virus causing major public health problems. Since the pandemic of 2009, there has been a rapid rise in human Influenza virus characterization. However, little data is available in Tunisia regarding its genetic evolution. Read More

J Neurol Surg B Skull Base 2021 Feb 3;82(Suppl 1):S57-S58. Epub 2020 Nov 3.

Department of Neurosurgery, Shioda Memorial Hospital, Chiba, Japan.

Surgical removal of large jugular foramen schwannomas with intra- and extracranial extension is challenging. The treatment goal is a gross total resection of the tumor without causing surgical complications, including facial nerve paresis, hearing disturbance, dysphagia, hoarseness, and cerebrospinal fluid (CSF) leakage, in addition to the brain stem injury. We present a surgical video in a patient with a dumbbell-shaped glossopharyngeal schwannoma. Read More

J Orthop Case Rep 2020 Nov;10(8):23-26

Department of Orthopaedics, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

Introduction: Aneurysmal bone cyst (ABC) is a benign intraosseous lesion, usually seen before the age of 20 years and is a lesion filled with blood cavities causing a blowout distension of the bone. It constitutes to about 1% of benign bone tumors. Although benign, a large lesion is liable to develop pathological fracture, so needs prompt addressal. Read More

J Fish Dis 2021 Mar 9. Epub 2021 Mar 9.

Department of Exotic Animal and Wildlife Medicine and Clinic, University of Veterinary Medicine, Budapest, Hungary.

The aquaculture industry is growing and includes the farming and breeding of more than 580 aquatic species worldwide. The rainbow trout (Oncorhynchus mykiss, Walbaum 1792) is the most commonly bred trout species in Hungary. As broodfish form the basis of most fish farms, investigation into tumours occurring in trout, although under-researched, has proven to be a valuable and necessary field of study. Read More

Heart Views 2020 Jul-Sep;21(3):166-170. Epub 2020 Oct 13.

King Abdulaziz Cardiac Center, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.

Background: The COVID-19 Pandemic has put enormous pressure on the healthcare system globally, causing many healthcare organizations to cancel elective admission for coronary angiograms. The purpose of this study is to assess changes in ST segment elevation myocardial infarction (STEMI) practice, including the number of patients, door to balloon time and time from the onset of symptoms until reperfusion therapy in a tertiary center in Saudi Arabia.

Methods: This is a single center retrospective observational study, comparing all STEMI patients in the last five months of 2019 (Pre-COVID-19 period) with the first 5 months of 2020 (COVID -19 period) in regards to the volume of STEMI patients, symptoms onset to ER arrival time, door to balloon timing and the reperfusion therapy strategy. Read More

J Mol Biol 2021 Mar 4;433(9):166910. Epub 2021 Mar 4.

Department of Life Science, Pohang University of Science and Technology, Pohang, Republic of Korea. Electronic address:

The Smc5/6 complex facilitates chromosome replication and DNA break repair. Within this complex, a subcomplex composed of Nse1, Nse3 and Nse4 is thought to play multiple roles through DNA binding and regulating ATP-dependent activities of the complex. However, how the Nse1-Nse3-Nse4 subcomplex carries out these multiple functions remain unclear. Read More

Viruses 2021 02 27;13(3). Epub 2021 Feb 27.

Laboratory of Veterinary Infectious Disease, College of Veterinary of Medicine, Jeonbuk National University, Iksan 54596, Korea.

Wild aquatic birds, a natural reservoir of avian influenza viruses (AIVs), transmit AIVs to poultry farms, causing huge economic losses. Therefore, the prevalence and genetic characteristics of AIVs isolated from wild birds in South Korea from October 2019 to March 2020 were investigated and analyzed. Fresh avian fecal samples (3256) were collected by active monitoring of 11 wild bird habitats. Read More

Eur J Ophthalmol 2021 Mar 1:1120672121997305. Epub 2021 Mar 1.

Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Introduction: We describe the phenotype of a variant lattice corneal dystrophy (LCD) potentially caused by a novel variant c.1772C>T p.(Ser591Phe) in exon 13 of the transforming growth factor beta-induced gene. Read More

Qatar Med J 2021 18;2021(1):01. Epub 2021 Feb 18.

Department of Obstetrics and Gynecology, Al Wakra Hospital, Hamad Medical Corporation, Al Wakra, Qatar.

Epidural analgesia or anesthesia is a common procedure for pain relief, especially in obstetrics. Pneumorrhachis and pneumothorax are rare complications of epidural analgesia. They are considered asymptomatic entities but have recently caused increased morbidity and mortality. Read More

Neurol Med Chir (Tokyo) 2021 Feb 26. Epub 2021 Feb 26.

Department of Neurosurgery, Nagoya University Graduate School of Medicine.

Internal trapping with coils is an established treatment of symptomatic large non-branching thrombosed fusiform vertebral artery aneurysms (VAA). However, when perforators arise near the aneurysm neck, parent artery occlusion has a high risk of causing medullary infarction. As an alternative treatment, we performed short-segment internal trapping of the artery using n-butyl-2-cyanoacrylate (NBCA) and coils (bird's nest trapping). Read More

Perm J 2020 Dec;25

Internal Medicine Department, Michigan State University, Sparrow Hospital, East Lansing, MI.

Introduction: Pyomyositis has been described in association with hematological malignancies. It is rarely associated with solid cancers, particularly colorectal carcinoma. Colorectal carcinoma can present with local or systemic abscesses by causing perforation of the colonic mucosa, followed by local or hematogenous spread of infection. Read More

Plant Dis 2021 Feb 25. Epub 2021 Feb 25.

Inner Mongolia University, 12576, Inner Mongolia Potato Engineering & Technology Research Center, Hohhot, Inner Mongolia, China;

Blackleg on potato plants () is caused by spp. and spp. (Charkowski, 2018) worldwide. Read More

Eur Heart J Case Rep 2020 Dec 8;4(6):1-5. Epub 2020 Nov 8.

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, 101 Daehang-ro, Chongno-gu, Seoul110-744, Republic of Korea.

Background: Coronary vasospasm is primarily characterized by transient and reversible vasoconstriction causing myocardial ischaemia and can manifest with various clinical features, including syncope.

Case Summary: A 50-year-old man presented with recurrent episodes of syncope for 3 days. The last syncope history occurred during an early morning walk, accompanied by dizziness and loss of consciousness. Read More

Br J Neurosurg 2021 Feb 20:1-6. Epub 2021 Feb 20.

Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO, USA.

Background: Considerations of the sacroiliac joint (SIJ) and its role in causing lower back and limb pain have taken a secondary role ever since Mixter and Barr's hallmark article in 1934 on the herniated nucleus pulposus. However, recent literature has highlighted the contribution of sacroiliac joint degeneration in the development of failed back surgery syndrome (FBSS), especially in patients undergoing lumbar or lumbosacral spinal fusion surgeries. Many reports have studied the anatomy, physiology, and clinical significance of the sacroiliac joint, but none have linked its dysfunction with other spinal deformities. Read More