72 results match your criteria secondary sheehan's


A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.

J Med Case Rep 2021 May 8;15(1):229. Epub 2021 May 8.

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis.

Case Presentation: We describe the case of a 45-year-old Ethiopian woman who presented with generalized fatigue for 18 years which progressed to anorexia, nausea, vomiting, diarrhea, and abdominal pain of 6 years' duration, for which she was treated symptomatically throughout these years. Read More

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Hypopituitarism: A Rare but Often Neglected Condition.

Indian J Crit Care Med 2020 May;24(5):350-352

Department of General Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.

Pituitary insufficiency is an uncommon disorder. The most common cause is compression due to a pituitary mass. Other causes include inflammatory damage and vascular injury like postpartum pituitary apoplexy. Read More

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Evaluation of bone texture imaging parameters on panoramic radiographs of patients with Sheehan's syndrome: a STROBE-compliant case-control study.

Osteoporos Int 2019 Nov 2;30(11):2257-2269. Epub 2019 Aug 2.

Department of Clinical Dentistry, Postgraduate Program in Dentistry, Federal University of Ceará, Alexandre Baraúna St 949, Rodolfo Teofilo, Fortaleza, Ceará, 60430-160, Brazil.

Sheehan's syndrome (SHS) is a rare condition related to the risk of osteoporosis and evaluation of bone texture imaging features on panoramic radiographs would be suitable for this condition, which was the aim of the present study. Fractal dimension, lacunarity, and trabecular morphologic aspects were significantly altered in these patients.

Introduction: SHS is an important public health problem particularly in developing countries. Read More

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November 2019

Hypopituitarism other than sellar and parasellar tumors or traumatic brain injury assessed in a tertiary hospital.

Pak J Med Sci 2019 Jul-Aug;35(4):1149-1154

Dr. Najmul Islam, FRCP. Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.

Objective: Data regarding the etiology, clinical and biochemical patterns in hypopituitarism is scant for Pakistan. We describe the characteristics of patients with hypopituitarism other than sellar and parasellar tumors or traumatic brain injury from a tertiary care center in Pakistan.

Methods: We conducted a retrospective descriptive study in the Aga Khan University Hospital, Karachi, Pakistan. Read More

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An Unusual Case of Intractable Vomiting: Unravelling the Present, Through the Past!

J Assoc Physicians India 2018 Jun;66(6):88-91

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

A 54 year old lady presented to our institute with a history of low grade fever for one week associated with occasional loose stools, vomiting and severe malaise. Initial evaluation revealed low serum sodium. An initial diagnosis of acute gastroenteritis with secondary hyponatremia was made. Read More

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A rare endocrine cause of electrical storm - a case report.

Eur Heart J Case Rep 2017 Dec 7;1(2):ytx008. Epub 2017 Nov 7.

Department of Cardiology, Seth G S Medical College and King Edward VII Memorial Medical College, Acharya Donde Marg, Parel, Mumbai 400012, India.

Sheehan's syndrome, also called Simmond's syndrome, postpartum apoplexy, postpartum pituitary necrosis, and postpartum panhypopituitary syndrome, is the name given to postpartum hypopituitarism. The syndrome is caused by an infarction in the adenohypophysis, usually precipitated by massive uterine haemorrhage and hypovolemic shock during or after childbirth. Extensive destruction of pituitary cells results in varying degree of hypopituitarism. Read More

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December 2017

Impact of etiology, age and gender on onset and severity of hyponatremia in patients with hypopituitarism: retrospective analysis in a specialised endocrine unit.

Endocrine 2017 Nov 14;58(2):312-319. Epub 2017 Sep 14.

Department of Neuroendocrinology, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Belgrade, Serbia.

Background: Hyponatremia can unmask hypopituitarism and secondary adrenal insufficiency. This is important, since the need to screen for steroid deficiency, in patients with hyponatremia is often neglected.

Patients And Methods: In a retrospective study, twenty-five patients (13f/12m, age 58. Read More

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November 2017

[Atypical and rare cardiac revelation about Sheehan's syndrome: A report of three cases].

Ann Cardiol Angeiol (Paris) 2017 Sep 24;66(4):239-242. Epub 2017 Jan 24.

Service d'endocrinologie, diabétologie, maladie métaboliques et nutrition, CHU Med VI, Marrakech 40000, Maroc.

Sheehan syndrome is a potentially serious complication in the postpartum period corresponding to ischemic necrosis of the anterior pituitary related to postpartum haemorrhage. We report three original observations showing an unusual mode of revelation of this syndrome. The first observation is that of a 46-year-old patient admitted initially to resuscitation for a recovered cardiorespiratory arrest, severe hypoglycemia and profound hyponatremia. Read More

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September 2017

Hypopituitarism in a Dengue Shock Syndrome Survivor without known Pituitary Adenoma.

Trop Biomed 2016 Dec;33(4):746-752

Division of Endocrinology, Department of Internal Medicine, University of Malaya, 59100 Kuala Lumpur, Malaysia.

Dengue infection is endemic in South East Asia and parts of the Americas. Dengue hemorrhagic fever is characterized by vascular permeability, coagulation-disorders and thrombocytopenia, which can culminate in hypotension i.e. Read More

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December 2016

The price of a 15-year delay in diagnosis of Sheehan's syndrome.

Proc (Bayl Univ Med Cent) 2016 Apr;29(2):212-3

Department of Medicine, Civil Hospital, Ahmedabad, India (Parikh, Makwana, H. Buch), and SAL Hospital, Ahmedabad, India (V. Buch).

We describe a case of a 48-year-old woman who presented with a 15-year history of recurrent episodes of hypoglycemia and hyponatremia leading to altered behavior and generalized seizures. She underwent full clinical assessment, endocrine tests, and a pituitary magnetic resonance scan that showed pananterior hypopituitarism secondary to postpartum pituitary necrosis (Sheehan's syndrome). She was commenced on appropriate hormone replacement therapy, which led to significant improvement in lethargy, anorexia, muscle weakness, and episodes of hypoglycemia. Read More

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[Sheehan's syndrome--a forgotten disease with 100 years' history].

Przegl Lek 2015 ;72(6):313-20

Although named after Harold Sheehan, postpartum ischemic pituitary necrosis was reported for the first time 100 years ago in Przeglad Lekarski by Leon Konrad Gliński. In the majority of cases, the syndrome is a consequence of severe postpartum bleeding episode resulting in severe hypotension or hemorrhagic shock. The frequency of Sheehan's syndrome has decreased in developed countries as a result of improved obstetrical care, but this clinical entity remains a common cause of hypopituitarism in developing countries. Read More

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Religion, coping and outcome in out-patients with depression or diabetes mellitus.

Acta Psychiatr Scand 2016 06 15;133(6):489-96. Epub 2015 Dec 15.

Department of Psychological Medicine, College of Medicine, University of Nigeria, Enugu, Nigeria.

Objective: The study assesses the association between religiosity and coping style with the outcome of depression and diabetes.

Method: Using a simple random sampling, we recruited 112 participants with diabetes and an equal number with depression consecutively, matching for gender. Religiosity was determined using Religious Orientation Scale (revised) (ROS-R), coping styles with Brief Religious Coping (Brief RCOPE) scale and Mental Adjustment to Cancer (MAC) scale (adapted). Read More

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Pituitary injury and persistent hypofunction resulting from a peripartum non-hemorrhagic, vaso-occlusive event.

Endocrinol Diabetes Metab Case Rep 2015 1;2015:150001. Epub 2015 Jun 1.

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology , McGill University Health Center , 687 Pine Avenue West F 6.58, Montreal, Quebec , Canada H3A 1A1.

Unlabelled: Cerebral vascular accidents are caused by vasospasm when induced by preeclampsia or by dopamine agonists. However, six arteries nourish the pituitary and prevent against vasospasm-induced damage, which up until now has not been thought to occur. Bromocriptine was used to arrest lactation in a 31-year-old with secondary amenorrhea following preeclampsia and fetal demise at 28 weeks gestation. Read More

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[Sheehan's syndrome after obstetric hemorrhage].

Rev Esp Anestesiol Reanim 2014 Dec 15;61(10):575-8. Epub 2014 Mar 15.

Servicio de Anestesiología y Reanimación, Hospital Teresa Herrera, Complejo Hospitalario Universitario de A Coruña, A Coruña, España.

Sheehan's syndrome is described as panhypopituitarism secondary to a pituitary hypoperfusion during or just after obstetric hemorrhage. Advances in obstetric care make this syndrome quite unusual, but some cases are reported in underdeveloped countries. Clinical presentation may change depending on the severity of the hormone deficiencies. Read More

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December 2014

Recurrent hypoglycemia…: A less well-known presentation of Sheehan's syndrome.

J Postgrad Med 2013 Oct-Dec;59(4):318-20

Department of Medicine, Government Medical College and S.S.G. Hospital, Vadodara, Gujarat, India.

Sheehan's syndrome is a rare cause of recurrent hypoglycemia. We present a case of a middle aged woman who presented with recurrent life threatening hypoglycemia. Based on a past history of severe post partum hemmorhage and a clinical picture of myxedema and secondary amennorhea, laboratory and neuroimaging was undertaken to confirm a diagnosis of Sheehan's syndrome. Read More

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November 2014

Complete hydatidiform mole and a coexistent fetus following ovulation induction in a patient with Sheehan's syndrome: a first case report and review of literature.

Arch Gynecol Obstet 2014 May 8;289(5):1145-50. Epub 2013 Dec 8.

Reproductive Medicine Center, Department of Obstetrics and Gynaecology, The First People's Hospital of Foshan, Foshan, 528000, Guangdong, People's Republic of China,

Pregnancy in Sheehan's syndrome (SS) is extremely rare. We present the first reported case of twin pregnancy with complete hydatiform mole (CHM) and a coexistent fetus (CHCF) in a patient with SS. A 29-year-old Chinese patient with SS became pregnant following one cycle of ovulation induction with human menopausal gonadotropin after secondary infertility. Read More

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Deep vein thrombosis in a patient of Sheehan's syndrome: Autoimmunity or hypercoagulabilty.

Indian J Endocrinol Metab 2013 Oct;17(Suppl 1):S105-6

Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India.

Introduction: Literature is inconsistent whether patients with hypopituitarism have increased risk of thrombosis. Recent data has shown problems with the coagulation system in Sheehan's syndrome (SS). Here, we describe a case of SS which presented with deep vein thrombosis. Read More

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October 2013

A ray of hope for a woman with Sheehan's syndrome.

Authors:
Deepti Jain

BMJ Case Rep 2013 Feb 4;2013. Epub 2013 Feb 4.

Department of Gynaecology, Chotu Ram Hospital, Rohtak, Haryana, India.

A 25-year-old woman presented with a history of secondary amenorrhoea for the last 3 years, coinciding with her delivery. She delivered at home and had massive postpartum haemorrhage. She was brought in a state of circulatory collapse to the nearest teaching hospital, where she was resuscitated. Read More

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February 2013

Flexion contractures of the legs as the manifestation of secondary adrenal insufficiency due to Sheehan's syndrome.

J Orthop Sci 2014 May 21;19(3):502-6. Epub 2012 Sep 21.

Department of Orthopaedic Surgery, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan,

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Acute renal failure: A rare presentation of Sheehan's syndrome.

Indian J Endocrinol Metab 2012 Mar;16(2):306-9

Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India.

Sheehan's syndrome occurs as a result of ischemic pituitary necrosis secondary to severe postpartum bleeding. It is one of the most common causes of hypopituitarism, characterized by variable clinical presentation. Acute kidney injury occurs rarely in Sheehan's syndrome and most of the cases have been found to be precipitated by rhabdomyolysis. Read More

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Acute hypopituitarism in a pregnant patient after cardiac gunshot injury.

J Clin Anesth 2011 Aug 8;23(5):414-7. Epub 2011 Jul 8.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

Sheehan's syndrome is a well described entity that refers to hypopituitarism with pituitary infarction secondary to postpartum shock or hemorrhage. Antepartum pituitary infarction is a very rare condition that has been reported only in patients with longstanding type 1 diabetes mellitus or uncontrolled gestational diabetes. A case of severe, acute hypopituitarism in the setting of hemorrhagic shock from a gunshot wound is presented. Read More

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A Patient with Postpartum Hypopituitarism (Sheehan's Syndrome) Developed Postpartum Autoimmune Thyroiditis (Transient Thyrotoxicosis and Hypothyroidism): A Case Report and Review of the Literature.

J Thyroid Res 2011 11;2011:413026. Epub 2011 Apr 11.

Department of Endocrinology and Metabolism, Aizawa Hospital, 2-5-1 Honjo, Mtasumoto 390-8521, Japan.

A 36-year-old woman with postpartum hypopituitarism (Sheehan's syndrome: SS) developed postpartum autoimmune thyroiditis (PPAT). She delivered a baby by Caesarean section (620 mL blood loss). At 1 month post partum, she developed thyrotoxicosis due to painless thyroiditis (autoimmune destructive thyroiditis). Read More

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A case of Sheehan's syndrome that manifested as bilateral ptosis.

J Korean Med Sci 2011 Apr 28;26(4):580-2. Epub 2011 Mar 28.

Department of Internal Medicine, College of Medicine, Dongguk University, 307 Dongdae-ro, Gyeongju, Korea.

Hypothyroidism can cause a variety of signs and symptoms of the neuromuscular system. However, ptosis in a patient with hypothyroidism is very rare. We report here on a case of central hypothyroidism that was due to Sheehan's syndrome and it manifested as bilateral ptosis in a 51-yr-old woman. Read More

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Assessment of bleeding disorders in Sheehan's syndrome: are bleeding disorders the underlying cause of Sheehan's syndrome?

Platelets 2011 6;22(2):92-7. Epub 2010 Dec 6.

Department of Endocrinology, Faculty of Medicine, Dicle University School of Medicine, Diyarbakir, Turkey.

Sheehan's syndrome (SS) is an adenopituitary insufficiency caused by hypovolemia secondary to excessive blood loss during or after childbirth. However, the mechanism of postpartum hemorrhage and ischemia is not clear. We aimed to evaluate the bleeding disorders among patients with SS, in comparison with healthy controls. Read More

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Sheehan's syndrome presenting as postpartum seizures.

Anaesth Intensive Care 2010 May;38(3):571-3

Department of Anesthesia and Intensive Care, Institute of Medical Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

We report a case where a patient presented with generalised tonic-clonic seizures secondary to nausea, vomiting and dehydration. She had suffered a postpartum haemorrhage six months previously. On laboratory assessment hyponatraemia and low hormone concentrations suggested pituitary failure. Read More

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Practice of symptomatic treatment in the era of evidence-based medicine: report of 2 cases of diagnosis of Sheehan's syndrome delayed till eighth decade.

BMJ Case Rep 2010 May 6;2010. Epub 2010 May 6.

Hera General Hospital, Makkah, Saudi Arabia.

Sheehan's syndrome, first described in 1937, is characterised by postpartum haemorrhage, pituitary necrosis, lactational failure and hypopitutarism. Presentation is variable and late presentations are not unusual due to partial ischaemic injury of the pituitary and gradual loss of endocrine function. A history of postpartum haemorrhage is usual but in some cases it is not elicited. Read More

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[Severe hyponatremia revealing Sheehan's syndrome].

Rev Med Liege 2009 Jul-Aug;64(7-8):398-402

Service d'Endocrinologie, CHR Citadelle, Liège, Belgique.

We describe the case of a young woman admitted for severe hyponatremia due to hypopituitarism caused by a Sheehan's syndrome. Sheehan's syndrome is a rare disorder. It develops after obstetrical hemorrhage that causes ischemic necrosis of the pituitary gland. Read More

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November 2009

A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia.

Acta Biomed 2009 Apr;80(1):73-6

Department of Gynecology, Obstretrics and Neonatology, University of Parma, University Hospital of Parma, Italy.

Sheehan's syndrome is a well-known cause of panhypopituitarism secondary to pituitary apoplexy, that generally occurs after an intra- or postpartum bleeding episode characterized by severe hypertension or hemorrhagic shock. The diagnosis can be difficult and is often formulated after some years from the syndrome occurrence. We report the case of a woman with an early diagnosis of early-onset Sheehan's syndrome associated with severe hyponatremia following dystocic childbirth complicated by postpartum hemorrhage. Read More

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