Pregnancy Hypertens 2018 Oct 10;14:252-259. Epub 2018 Mar 10.
Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Institute for Molecular Medicine Finland, HiLIFE Unit, University of Helsinki, Helsinki, Finland; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.
Objectives: To study first and second/third trimester levels of soluble fms-like tyrosine kinase 1 (sFlt1), placental growth factor (PlGF) and soluble endoglin (sEng) in FINNPEC case-control cohort. The participants were further divided into subgroups based on parity and onset of the disease. Recommended cut-off values in aid of pre-eclampsia (PE) prediction and diagnosis were also tested. Read More