10,353 results match your criteria sebaceous


Anagen Effluvium after Therapeutic Scalp Surgery: Unreported Phenomenon.

Skin Appendage Disord 2021 Jun 23;7(4):311-314. Epub 2021 Mar 23.

Dermatology, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.

Introduction: Many procedures are performed on the scalp, such as excision of pilar and sebaceous cysts, melanocytic nevi, and reduction surgery for scarring alopecia, among others. In hair transplants, telogen effluvium is often reported 3 months after surgery; however, hair loss usually happens much earlier, around second week after the procedure, not compatible with the time required for hair to enter telogen and exogenous phases in normal conditions.

Case Reports: We report 3 cases of anagen hair loss 4 weeks after surgeries, with perilesional trichoscopy suggesting anagen effluvium, with typical signs such as black dots and exclamation hairs. Read More

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Lower Eyelid Orbicularis Oculi Myocutaneous Flap: A Feasible Technique for Full Thickness Upper Eyelid Reconstruction.

World J Plast Surg 2021 May;10(2):98-102

Istituto Nazionale dei Tumori Fondazione G. Pascale Via M. Semmola, 52 - 80131 Naples, Italy.

Basal cell carcinoma (BCC) is the most frequent malignant eyelid tumor, followed by squamous cell carcinoma, sebaceous gland carcinoma and malignant melanoma. These eyelid malignancies represent main reason for eyelid reconstruction in ophthalmoplastic surgery which can be challenging. Lower eyelid orbicularis oculi myocutaneous flap was used for reconstructive purpose in four consecutive patients with a full thickness upper eyelid BCC. Read More

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[Malassezia spp.: interactions with topically applied lipids-a review : Malassezia and topically applied lipids].

Hautarzt 2021 Jul 24. Epub 2021 Jul 24.

Symrise AG, Muehlenfeldstr. 1, 37603, Holzminden, Deutschland.

Lipophilic Malassezia yeasts are an important part of the human resident skin flora, especially in seborrheic areas. Besides mutualistic interactions with the host they are also linked to diseases although the specific causes are not yet comprehensively understood. The amount of available lipids on the skin correlates with the Malassezia density and also with the occurrence of certain diseases like tinea versicolor. Read More

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Trop2 Expression in Extramammary Paget's Disease and Normal Skin.

Int J Mol Sci 2021 Jul 19;22(14). Epub 2021 Jul 19.

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Extramammary Paget's disease (EMPD) is a rare skin cancer arising in the apocrine gland-rich areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor outcomes owing to the lack of effective systemic therapies. Trophoblast cell surface antigen 2 (Trop2), a surface glycoprotein, has drawn attention as a potential therapeutic target for solid tumors. Read More

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Cd34+ Stromal Cells/Telocytes in Normal and Pathological Skin.

Int J Mol Sci 2021 Jul 8;22(14). Epub 2021 Jul 8.

Department of Basic Medical Sciences, Faculty of Medicine, University of La Laguna, 38071 Tenerife, Spain.

We studied CD34+ stromal cells/telocytes (CD34+SCs/TCs) in pathologic skin, after briefly examining them in normal conditions. We confirm previous studies by other authors in the normal dermis regarding CD34+SC/TC characteristics and distribution around vessels, nerves and cutaneous annexes, highlighting their practical absence in the papillary dermis and presence in the bulge region of perifollicular groups of very small CD34+ stromal cells. In non-tumoral skin pathology, we studied examples of the principal histologic patterns in which CD34+SCs/TCs have (1) a fundamental pathophysiological role, including (a) fibrosing/sclerosing diseases, such as systemic sclerosis, with loss of CD34+SCs/TCs and presence of stromal cells co-expressing CD34 and αSMA, and (b) metabolic degenerative processes, including basophilic degeneration of collagen, with stromal cells/telocytes in close association with degenerative fibrils, and cutaneous myxoid cysts with spindle-shaped, stellate and bulky vacuolated CD34+ stromal cells, and (2) a secondary reactive role, encompassing dermatitis-e. Read More

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Non-thymoma-associated exfoliative dermatitis in a European shorthair cat: A case report.

Vet Med Sci 2021 Jul 22. Epub 2021 Jul 22.

Department of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.

The current case report presents a case of non-thymoma-associated exfoliative dermatitis in an 8-year-old European Shorthair female cat. The animal displayed extensive alopecia and excessive peeling of the epidermis. There were no other apparent disorders, except for the skin lesions. Read More

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GLUT1 Expression in Cutaneous Sebaceous Lesions Determined by Immunohistochemical Staining Patterns.

Dermatopathology (Basel) 2021 Jul 5;8(3):258-264. Epub 2021 Jul 5.

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.

GLUT1 is a membrane associated carrier protein that functions in the physiologic transport of glucose across cell membranes. Multiple studies have shown an increased GLUT1 expression in various tumor types and a role in cancer prognosis. The aim of this study was to determine whether cutaneous sebaceous lesions have a differential expression of GLUT1 by immunohistochemistry (IHC). Read More

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Peripunctal Mass Lesions: Clinicopathological Analysis and Surgical Outcomes-A Multicentric Series.

Ophthalmic Plast Reconstr Surg 2021 Jul 19. Epub 2021 Jul 19.

Ophthalmic Plastic Surgery and Ocular Oncology Services, Advanced Eye Hospital & Institute, A Unit of Dr. Agarwal's Eye Hospital, Navi Mumbai, India Ophthalmic Plastic Surgery and Ocular Oncology Services, Aditya Jyot Eye Hospital, Mumbai, India Ophthalmic Plastic Surgery and Ocular Oncology Services, Aayush Eye Clinic, A Unit of Dr. Agarwal's Eye Hospital, Mumbai, India Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital, Mumbai, India Department of Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Sankara Nethralaya, Chennai, India EyeHUB Vision Care, Faridabad, India Ophthalmic Plastic Surgery and Ocular Oncology Services, L J Eye Institute, Ambala, India Ophthalmic Plastic Surgery & Facial Aesthetics, L V Prasad Eye Institute, Hyderabad, India Department of Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, India Clinico-Path Laboratory, Chembur, Mumbai, India.

Purpose: To report the epidemiology, histopathological spectrum, and surgical outcomes of peripunctal mass lesions.

Methods: Multicentric retrospective case series involving 6 centers in India. All cases of peripunctal masses with histopathological diagnoses and minimum follow up of 3 months were included. Read More

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Necrotizing infundibular (ostial) crystalline folliculitis.

Clin Dermatol 2021 Mar-Apr;39(2):194-198. Epub 2020 Oct 16.

Department of Pathology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address:

Necrotizing infundibular crystalline folliculitis is a rare condition characterized by folliculocentric waxy papules in the seborrheic areas of adult patients, with intrafollicular filamentous birefringent crystalline deposits as the histopathologic clue. Although the real pathogenesis of necrotizing infundibular crystalline folliculitis remains unclear, the intrafollicular material seems to be derived from an interaction between such superficial microorganisms as gram-positive bacteria (Propionibacterium acnes, Staphylococcus spp), Malassezia yeasts, and sebaceous lipids. Topical or systemic antiacne agents or antimycotics appear to be effective therapy. Read More

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October 2020

Infiltrative Sebaceous Carcinoma Presenting as a "Tumor Tarsorrhaphy".

Ophthalmic Plast Reconstr Surg 2021 Jul 15. Epub 2021 Jul 15.

Signature Healthcare/Brockton Hospital, Brockton, Massachusetts David G. Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear/Harvard Medical School, Boston, Massachusetts Ophthalmic Plastic Surgery, Department of Ophthalmology, Massachusetts Eye and Ear/Harvard Medical School, Boston, Massachusetts, U.S.A.

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A Novel Surgical Approach for Rhinophyma: Experience From a Cohort of Thirty Patients.

J Craniofac Surg 2021 Jul 15. Epub 2021 Jul 15.

Department of Dermatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai, China.

Background: Rhinophyma is the severe rosacea whit hypertrophy of sebaceous glands in nasal tissue, which severely influences the patient's appearance. Surgical therapy is the best method for treating moderate-to-severe rhinophyma. In this study, we used a new ameliorated scarification for 30 patients with moderate-to-severe rhinophyma. Read More

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Rare upper lip pleomorphic adenoma presents as cutaneous skin lesion: Case report.

Int J Surg Case Rep 2021 Jun 29;85:106142. Epub 2021 Jun 29.

Department of Surgery, King Khalid University Hospital, King Saud University, Saudi Arabia.

Introduction: Pleomorphic adenoma of the minor salivary gland is not uncommon. Although malignant lesion is the most common in the minor salivary glands, benign lesion has been also reported. Many ectopic sites for minor salivary gland including the lip have been reported mainly intra-orally. Read More

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Somatic KRAS mutation affecting codon 146 in linear sebaceous nevus syndrome.

Am J Med Genet A 2021 Jul 13. Epub 2021 Jul 13.

UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Linear Sebaceous Nevus Syndrome is a rare disorder that presents with nevus sebaceus in association with corneal dermoids, colobomas, choroidal osteomas, and arachnoid cysts. It is thought to represent a mosaic RASopathy. These are disorders characterized by postzygotic somatic mutation in genes involved in RAS/MAPK signaling pathway. Read More

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Shifts in the skin bacterial and fungal communities of healthy children transitioning through puberty.

J Invest Dermatol 2021 Jul 9. Epub 2021 Jul 9.

Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA. Electronic address:

Previous cross-sectional studies have shown that skin microbiomes in adults are distinct from children. However, the human skin microbiome in individuals as they sexually mature has not been studied as extensively. We performed a prospective, longitudinal study to investigate puberty-associated shifts in skin microbiota. Read More

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Can a radiofrequency device reduce the pore size?

Lasers Med Sci 2021 Jul 12. Epub 2021 Jul 12.

Department of Dermatology, Korea University Ansan Hospital, Korea University, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, Republic of Korea.

A facial pore is an empty funnel-shaped structure filled with cornified cylindrical plugs that can be cosmetically bothersome to some patients. In the previous report, the new unipolar radiofrequency (RF) device with a vacuum showed excellent skin tightening and patient satisfaction with improved pores. This study aims to confirm the treatment's efficacy with the new unipolar RF device on facial dilated pores by measuring quantitative sebum production differences and doing a histologic examination of pore size. Read More

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Case Report: A Frameshift Mutation in MSH2 Exon 2 in a Kidney Recipient With Muir-Torre Syndrome.

Front Oncol 2021 24;11:681780. Epub 2021 Jun 24.

Department of Pathology, Taicang Hospital of Traditional Chinese Medicine, Suzhou, China.

Muir-Torre syndrome (MTS), a rare subtype of Lynch syndrome, is mostly autosomal dominant, which is caused by germline mutations in DNA mismatch repair (MMR) genes, the resulting microsatellite instability (MSI) of which increases the risk of developing sebaceous and other visceral tumors. Several reports have showed an association between immunosuppressive agents and the progression of latent MTS. In this report, we described a 41-year-old man with a history of kidney transplantation, having a rapid growth of the nodule on the anterior chest under immunosuppressive therapy, which was histologically proved to be sebaceous carcinoma. Read More

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[Vulva anatomopathological peculiarities].

Ann Pathol 2021 Jul 6. Epub 2021 Jul 6.

Cabinet de dermatopathologie Mathurin Moreau, Paris 19(ième) ; service de pathologie, hôpital Cochin, Paris 14(e), France. Electronic address:

The vulva is the transition zone between the skin and the lower genital tract. As such, it presents histological specificities, comprises physiological modifications which are specific to it and is characterized by particular artifacts. Knowledge of them prevents many questions or even diagnostic errors. Read More

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Spectrum of AS-OCT features of ocular surface tumors and correlation of clinico-tomographic features with histopathology: a study of 70 lesions.

Int Ophthalmol 2021 Jul 9. Epub 2021 Jul 9.

Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, 500034, India.

Purpose: To assess the correlation between clinical and anterior segment optical coherence tomographic (AS-OCT) details and histopathological changes in various ocular surface lesions.

Methods: Prospective case series of 70 lesions in 65 patients.

Results: AS-OCT revealed epithelial changes in OSSN (n = 19; 44%), squamous papilloma (n = 3; 60%), nevus (n = 1; 33%), epithelial hyperplasia (n = 1; 33%), granular dystrophy (n = 1; 100%) and granulation tissue (n = 1; 100%); subepithelial changes in chronic inflammation (n = 4, 100%), lymphoma (n = 3; 100%) and arteriovenous malformation (n = 1; 100%); combined epithelial and subepithelial changes in OSSN (n = 24; 56%), squamous papilloma (n = 2; 40%), PEH (n = 3; 100%), nevus (n = 2; 67%), epithelial hyperplasia (n = 2; 67%), solar elastosis (n = 1; 100%), lobular capillary hemangioma (n = 1; 100%) and sebaceous carcinoma (n = 1; 100%). Read More

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Serum resistin levels and resistin gene polymorphism in patients with acne vulgaris: does it correlate with disease severity?

Int J Dermatol 2021 Jul 7. Epub 2021 Jul 7.

Medical Biochemistry and Molecular Biology Department, Menoufia University, Shebin EL-Kom, Egypt.

Background: Acne vulgaris is a disease that inflames the sebaceous gland with multiple etiologies. Many proinflammatory adipokines contribute to this pathogenesis. Resistin is a proinflammatory mediator that activates kappa B, a nuclear factor, and c-Jun N-terminal kinases pathways inducing toll-like receptor-2, interleukin-1, 6, and tumor necrosis factor alpha. Read More

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Trichoblastoma Arising From the Nevus Sebaceus of Jadassohn.

Cureus 2021 May 29;13(5):e15325. Epub 2021 May 29.

Dermatology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.

Trichoblastoma is a rare benign skin adnexal tumour, belonging to the category of trichogenic tumours. The clinical and histological findings may often be confused with basal cell carcinoma, a malignant epidermal skin tumour. We report here a case of a 70-year-old man presented with a dome-shaped, dark-pigmented nodule within a yellowish hairless plaque on the scalp. Read More

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Pleomorphic Adenoma of the Submandibular Gland in a 10-Year-Old Child: A Case Report.

Ear Nose Throat J 2021 Jul 8:1455613211022113. Epub 2021 Jul 8.

ENT Department, Fattouma Bourguiba Hospital of Monastir, Monastir, Tunisia.

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Read More

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Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.

Am J Surg Pathol 2021 May 12. Epub 2021 May 12.

*Department of Pathology, University Clinic Hospital, INCLIVA Biomedical Research Institute Departments of †Pathology §Biochemistry and Molecular Biology, University of Valencia, Valencia ‡Department of Pathology, Costa del Sol Health Agency, Málaga, Spain ∥Barr Dermatopathology, Laguna Beach, CA.

The term "cutaneous lymphadenoma" was coined in this journal for an unusual lymphoepithelial cutaneous adnexal neoplasm, possibly with immature pilosebaceous differentiation. Some authors further proposed that cutaneous lymphadenoma was an adamantinoid trichoblastoma. However, although a hair follicle differentiation is widely accepted, the fact that this is a lymphoepithelial tumor is not appropriately explained by the trichoblastoma hypothesis. Read More

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Dermoid Cyst with Intracranial Extension Presenting With Headache.

Mymensingh Med J 2021 Jul;30(3):860-862

Dr Shameem Ahmed, Chief Consultant Neurosurgeon, Department of Neurosurgery, Apollo Hospitals (Unit: International Hospital), Guwahati, India.

Dermoid cysts (DC) are benign cutaneous developmental anomalies comprising of hair follicles, sweat glands and sebaceous glands, and lined by stratified squamous epithelium. They are most commonly found on the face, lower back, and ovaries. We present a case of DC with intracranial extension in a 9 year old boy who presented with headache and a fluctuant scalp swelling. Read More

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The impact of isotretinoin on the pituitary-ovarian axis: An interpretative review of the literature.

Reprod Toxicol 2021 Jul 2;104:85-95. Epub 2021 Jul 2.

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

Isotretinoin (13-cis-retinoic acid), a derivative of vitamin A, is used in the treatment of severe acne resulting in sebum suppression induced by sebocyte apoptosis. Isotretinoin treatment is associated with several adverse effects including teratogenicity, hepatotoxicity, and dyslipidemia. Isotretinoin's effects on endocrine systems and its potential role as an endocrine disruptor are not yet adequately investigated. Read More

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Sebaceous carcinoma of the vulva treated with sentinel lymph node biopsy: a case report and literature review.

Int Cancer Conf J 2021 Jul 5;10(3):239-243. Epub 2021 May 5.

Department of Gynecology and Obstetrics, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507 Japan.

Sebaceous carcinoma (SC) is a rare and aggressive cutaneous malignancy. It often occurs on the eyelid, where it is called periocular SC, while extraocular SC mainly occurs on the head and heck. Extraocular vulvar SC is extremely rare; only nine cases have been described in the literature, and the optimal treatment strategy is unknown. Read More

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Vulvar Fordyce adenitis: A cohort of 45 women.

Ann Dermatol Venereol 2021 Jun 30. Epub 2021 Jun 30.

Study group for anogenital diseases, French Society of Dermatology, Maison de la Dermatologie, 10, cité Malesherbes, 75009 Paris, France; Private Vulvar Clinic, 4, rue Léon-Delhomme, 75015 Paris, France.

Background: Recurrent episodes of painful papules and nodules, mostly located on the labia minora, have been reported under the denominations of vulvar sebaceous adenitis (14 published cases) and vulvar acne (16 published cases).

Objectives: The primary aim of this study was to delve further into the clinical and pathological features of this condition. The secondary aim was to collect therapeutic data. Read More

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Thymoliposarcoma with sebaceous differentiation and MDM2 amplification.

Pathol Int 2021 Jul 2. Epub 2021 Jul 2.

Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.

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Gradually progressing painless lower lid mass.

Cytopathology 2021 Jul 2. Epub 2021 Jul 2.

Department of Cytology and Gynaecological Pathology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.

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Adjuvant radiation therapy for malignant tumours of the eyelid: Experience from a tertiary cancer centre in India.

Natl Med J India 2020 Sep-Oct;33(5):271-275

Department of Radiation Oncology, Dr B.R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

Background: . Tumours of the eyelid are a rare subgroup of neoplasms with varied histology and inherent differences in clinical behaviour. Surgery is the standard of care, and adjuvant radiation therapy (RT) is given in the presence of features suggesting a high risk of local recurrence. Read More

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The Role of KRAS Mutations in Cortical Malformation and Epilepsy Surgery: A Novel Report of Nevus Sebaceous Syndrome and Review of the Literature.

Brain Sci 2021 Jun 16;11(6). Epub 2021 Jun 16.

Rare and Complex Epilepsy Unit, Department of Neuroscience, Bambino Gesù Children's Hospital IRCCS, Member of European Reference Network EpiCARE, 00165 Rome, Italy.

The rare nevus sebaceous (NS) syndrome (NSS) includes cortical malformations and drug-resistant epilepsy. Somatic RAS-pathway genetic variants are pathogenetic in NS, but not yet described within the brain of patients with NSS. We report on a 5-year-old boy with mild psychomotor delay. Read More

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