4,914 results match your criteria searched november


Differences in survival and mortality in minority ethnic groups with dementia: A systematic review and meta-analysis.

Int J Geriatr Psychiatry 2021 Jun 18. Epub 2021 Jun 18.

Department of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Objectives: Although there are disparities in both risk of developing dementia and accessibility of dementia services for certain minority ethnic groups in the United States and United Kingdom, disparities in survival after a dementia diagnosis are less well-studied. Our objective was to systematically review the literature to investigate racial/ethnic differences in survival and mortality in dementia.

Methods: We searched Embase, Ovid MEDLINE, Global Health and PsycINFO from inception to November 2018 for studies comparing survival or mortality over time in at least two race/ethnicity groups. Read More

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Characteristics and effects of integrated nutrition and stimulation interventions to improve the nutritional status and development of children under 5 years of age: a systematic review and meta-analysis.

BMJ Glob Health 2021 Jul;6(7)

School of Health Sciences, Western Sydney University, Penrith South, New South Wales, Australia.

Introduction: Around 250 million children in low-income and middle-income countries are at risk of not fulfilling their developmental potential. There is a need to update syntheses investigating the effects of combined nutrition and stimulation interventions on children's growth and development and identify intervention characteristics associated with positive effects.

Methods: We did a systematic review to: (1) understand the effects of integrated nutrition and stimulation interventions versus (i) usual care and (ii) standalone nutrition or stimulation interventions, on the growth and development of children under five; (2) explore intervention characteristics (delivery strategies, behaviour change techniques, intensity and personnel) associated with positive effects. Read More

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Can omalizumab be used effectively to treat severe conjunctivitis in children with asthma? A case example and review of the literature.

World J Clin Pediatr 2021 Jul 9;10(4):48-52. Epub 2021 Jul 9.

Centre of Medical Education, Queens University Belfast, School of Medicine, Belfast BT9 7BL, United Kingdom.

A 14-year-old girl with poorly controlled asthma attended the difficult-to-treat asthma clinic for review. Although she has eosinophilia and significantly raised immunoglobulin E levels, she is not currently a candidate for omalizumab (Xolair). She also suffers from chronic urticaria, eosinophilic eosophagitis and severe conjunctivitis. Read More

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Amyloidosis of the urinary bladder: a systematic review and a proposed management algorithm.

Urology 2021 Jul 24. Epub 2021 Jul 24.

Urology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; Urology Department, The Pennine Acute Hospitals NHS Trust, Manchester, UK.

Objective: To propose an algorithm for the management of bladder amyloidosis based on a systematic review of the literature, given that the bladder is the second most commonly affected organ of the urinary tract in the course of systemic or localized amyloidosis.

Methods: We searched PubMed, Cochrane Library and Scopus databases utilizing PRISMA methodology from inception to November 30, 2020 (PROSPERO: CRD42020207855).

Results: We included 76 studies with 184 patients (9 case series and 67 case reports). Read More

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Community nurses' attitudes, knowledge and educational needs in relation to urinary continence, continence assessment and management: A systematic review.

J Clin Nurs 2021 Jul 22. Epub 2021 Jul 22.

School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland.

Aims And Objectives: To identify, appraise and summarise the available evidence relating to community nurses' attitudes, knowledge and educational needs in relation to urinary continence.

Background: Community nurses play a pivotal role in identifying and supporting individuals who experience urinary continence issues. Gaps in nurses' continence-related education and knowledge may contribute to sub-optimal assessment and management across the continuum of care. Read More

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Maternal Dietary Intake, Nutritional Status, and Macronutrient Composition of Human Breast Milk: Systematic Review.

Br J Nutr 2021 Jul 23:1-66. Epub 2021 Jul 23.

Wageningen University and Research, The Netherlands.

Introduction: Human breast milk is the best source of nutrition in early life, particularly during the first six months. Nevertheless, human breast milk composition is variable and more insight in the exact factors contributing to this variability is warranted. In this review, we explored the impact of maternal dietary intake and nutritional status (e. Read More

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The need of a system phantom for quantitative hybrid nuclear imaging of PET/CT: A systematic review.

Med J Malaysia 2021 Jul;76(4):551-561

Universiti Sains Malaysia, School of Medical Sciences, Medical Radiation Programme, Malaysia.

Introduction: There has already been a rising demand in utilising phantom for hybrid Positron Emission Tomography/ Computed Tomography (PET/CT) scanner of nuclear imaging. This review further clarifies this topic and investigates how the previous research phantoms operated with the need for quantitative hybrid nuclear imaging of PET/CT while providing a relatively high image quality when it was performed. In this article, the necessity of previous and current phantom studies in hybrid nuclear imaging of PET/CT scanners is reviewed. Read More

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Efficacy and Tolerability of Evogliptin in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis with Bayesian Inference Through a Quality-management System.

Clin Ther 2021 Jul 22. Epub 2021 Jul 22.

College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea.

Purpose: Evogliptin is one of the latest dipeptidyl peptidase-4 (DPP-4) inhibitor, and a number of clinical trials have been performed following its development, including several randomized controlled trials (RCTs) performed to evaluate its efficacy and tolerability. In our study, we performed a systematic review and meta-analysis of its efficacy and tolerability by collecting RCTs and confirmed the results with Bayesian inference. Moreover, an updated quality-management system was integrated into the study process of systematic review. Read More

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Effect of capsular tension ring on optical and multifunctional lens position outcomes: a systematic review and a meta-analysis.

Int Ophthalmol 2021 Jul 24. Epub 2021 Jul 24.

Department of Ophthalmology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China.

Aim: To evaluate the effect of capsular tension rings with multifunctional lens position and optical outcomes.

Methods: We defined multifunctional lens as more than improving vision, but also to restore visual quality. PubMed, EMBASE, Cochrane Library and Scopus were searched for English-language articles published up to November 11, 2020. Read More

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Adverse Events of Prone Positioning in Mechanically Ventilated Adults with Acute Respiratory Distress Syndrome.

Respir Care 2021 Jul 23. Epub 2021 Jul 23.

Master program in Physical Therapy and Rehabilitation, Carrera de Kinesiología, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago, Chile.

Introduction: Prone positioning is a therapy utilized globally to improve gas exchange, minimize ventilator-induced lung injury, and reduce mortality in acute respiratory distress syndrome (ARDS), particularly during the ongoing coronavirus disease 2019 (COVID-19) pandemic. While the respiratory benefits of prone positioning in ARDS have been accepted, the concurrent complications could be undervalued. Therefore, this study aimed to identify the adverse events related to prone positioning in ARDS, and secondarily, to collect strategies and recommendations to mitigate these adverse events. Read More

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Ethical Problems and Moral Distress in Primary Care: A Scoping Review.

Int J Environ Res Public Health 2021 Jul 16;18(14). Epub 2021 Jul 16.

Center for Nursing Research and Innovation, Vita-Salute San Raffaele University, 20132 Milan, Italy.

Background: Since 1997, nursing ethics research has focused on solving ethical dilemmas, enhancing decision-making strategies, and introducing professional education. Few studies describe the triggers of ethical dilemmas among primary care nurses. The aim of this study was to explore the moral distress and ethical dilemmas among primary care nurses. Read More

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Anti-HER2 antibody prolongs overall survival disproportionally more than progression-free survival in HER2-Positive metastatic breast cancer patients.

Breast 2021 Jul 8;59:211-220. Epub 2021 Jul 8.

Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

Background: This meta-analysis aimed to test the hypothesis that the HER2-positive metastatic breast cancer (mBC) patients treated with anti-HER2 antibodies in trial intervention arms have a greater prolongation of overall survival (OS) than of progression-free survival (PFS) and this extra-prolongation of median survival time in OS relates specifically to the anti-HER2 antibody.

Methods: The NCBI/Pubmed and Cochrane databases were searched systematically for HER2-positive or mBC trials published in English during January 1999-November 2017. Treatment arms with shorter PFS were considered as the "control" arm, whereas those with longer PFS as the "test" arm. Read More

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Evaluation of the reporting quality of clinical practice guidelines on lung cancer using the RIGHT checklist.

Transl Lung Cancer Res 2021 Jun;10(6):2588-2602

Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Background: In recent years, the number of clinical practice guidelines (CPGs) for lung cancer has increased, but the quality of these guidelines has not been systematically assessed so far. Our aim was to assess the reporting quality of CPGs on lung cancer published since 2018 using the International Reporting Items for Practice Guidelines in Health Care (RIGHT) instrument.

Methods: We systematically searched the major electronic literature databases, guideline databases and medical society websites from January 2018 to November 2020 to identify all CPGs for small cell and non-small cell lung cancer (NSCLC). Read More

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Transcranial Doppler Based Cerebrovascular Reactivity Indices in Adult Traumatic Brain Injury: A Scoping Review of Associations With Patient Oriented Outcomes.

Front Pharmacol 2021 6;12:690921. Epub 2021 Jul 6.

Section of Neurosurgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

Disruption in cerebrovascular reactivity following traumatic brain injury (TBI) is a known phenomenon that may hold prognostic value and clinical relevance. Ultimately, improved knowledge of this process and more robust means of continuous assessment may lead to advances in precision medicine following TBI. One such method is transcranial Doppler (TCD), which has been employed to evaluate cerebrovascular reactivity following injury utilizing a continuous time-series approach. Read More

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Scoping Review of Postinfectious Sequelae.

Foodborne Pathog Dis 2021 Jul 22:1-15. Epub 2021 Jul 22.

Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.

Previous economic estimates of infection with and chronic sequelae following infection lack sufficient data to establish the true burden of disease and its chronic sequelae. This scoping review aims to fill this gap by updating existing literature regarding the development of postinfectious sequelae following infection. Literature published between January 1, 2000, and November 6, 2018, in PubMed, EMBASE, and Scopus was searched for a wide range of postinfectious sequelae and economic estimate terms. Read More

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Ophthalmic artery Doppler in the prediction of preeclampsia.

Am J Obstet Gynecol 2021 Jan 8. Epub 2021 Jan 8.

Institute of Health Research, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.

The ophthalmic artery is an easily accessible vessel for Doppler assessment that provides information on the less accessible intracranial circulation. In women with preeclampsia, compared with normotensive pregnant women, there is a decrease in impedance to flow and an increase in velocities in the flow velocity waveforms from the ophthalmic arteries. This study aimed to report the methodology for ophthalmic artery Doppler and summarize findings from the clinical implementation of such assessment in the prediction of preeclampsia. Read More

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January 2021

How can we improve the quality of cataract services for all? A global scoping review.

Clin Exp Ophthalmol 2021 Jul 21. Epub 2021 Jul 21.

International Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Cataract is a leading cause of blindness and vision impairment globally. Cataract surgery is one of the most frequently performed operations worldwide, but good quality services are not universally available. This scoping review aims to summarise the nature and extent of published literature on interventions to improve the quality of services for age-related cataract globally. Read More

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The Lidcombe Program for Early Stuttering in Non-English-Speaking Countries: A Systematic Review.

Folia Phoniatr Logop 2021 Jul 21:1-14. Epub 2021 Jul 21.

Department of Speech Therapy and Audiology, Thomas More College of Applied Sciences, Antwerp, Belgium.

Background: The Lidcombe Program is a stuttering treatment approach for children between the ages of 3 and 6 years. Most papers about the Lidcombe Program, however, are based on studies conducted in native English-speaking countries. The aim of this paper is to systematically review the delivery and implementation of the Lidcombe Program in non-native English-speaking countries. Read More

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Digital Health Training Programs for Medical Students: Scoping Review.

JMIR Med Educ 2021 Jul 21;7(3):e28275. Epub 2021 Jul 21.

Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, United Kingdom.

Background: Medical schools worldwide are accelerating the introduction of digital health courses into their curricula. The COVID-19 pandemic has contributed to this swift and widespread transition to digital health and education. However, the need for digital health competencies goes beyond the COVID-19 pandemic because they are becoming essential for the delivery of effective, efficient, and safe care. Read More

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Stem cell therapy for dilated cardiomyopathy.

Cochrane Database Syst Rev 2021 Jul 21;7:CD013433. Epub 2021 Jul 21.

Interdisciplinary Centre for Health Studies CIESAL, Universidad de Valparaíso, Viña del Mar, Chile.

Background: Stem cell therapy (SCT) has been proposed as an alternative treatment for dilated cardiomyopathy (DCM), nonetheless its effectiveness remains debatable.

Objectives: To assess the effectiveness and safety of SCT in adults with non-ischaemic DCM.

Search Methods: We searched CENTRAL in the Cochrane Library, MEDLINE, and Embase for relevant trials in November 2020. Read More

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Cerebral palsy in children born after assisted reproductive technology: a meta-analysis.

World J Pediatr 2021 Jul 20. Epub 2021 Jul 20.

Department of Pediatrics, West China Second University Hospital, Sichuan University, 20 South Renmin Road 3rd Section, Wuhou District, Chengdu 610041, China.

Background: Several studies have assessed the association between cerebral palsy (CP) and assisted reproductive technology (ART), but the results remain controversial. We conducted a meta-analysis to evaluate the risk of CP after ART compared with natural conceptions and to examine CP risk separately in ART singletons, multiples and preterm births.

Methods: Web-based databases (PubMed, Embase, the Cochrane Library, and Web of Science) were searched until November 22, 2020. Read More

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Diagnostic test accuracy of telehealth assessment for dementia and mild cognitive impairment.

Cochrane Database Syst Rev 2021 07 20;7:CD013786. Epub 2021 Jul 20.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Background: Many millions of people living with dementia around the world are not diagnosed, which has a negative impact both on their access to care and treatment and on rational service planning. Telehealth - the use of information and communication technology (ICT) to provide health services at a distance - may be a way to increase access to specialist assessment for people with suspected dementia, especially those living in remote or rural areas. It has also been much used during the COVID-19 pandemic. Read More

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Association of Oral Anticoagulation With Stroke in Atrial Fibrillation or Heart Failure: A Comparative Meta-Analysis.

Stroke 2021 Jul 20:STROKEAHA120033910. Epub 2021 Jul 20.

HRB-Clinical Research Facility, National University of Ireland Galway. (C.R., C.J., E.L., R.M., M. Costello, A.A., J.F., A.S., M. Canavan, M.J.O.).

Background And Purpose: Atrial fibrillation and heart failure with reduced ejection fraction (HFrEF) are common sources of cardioembolism. While oral anticoagulation is strongly recommended for atrial fibrillation, there are marked variations in guideline recommendations for HFrEF due to uncertainty about net clinical benefit. This systematic review and meta-analysis evaluates the comparative association of oral anticoagulation with stroke and other cardiovascular risk in populations with atrial fibrillation or HFrEF in sinus rhythm and identify factors mediating different estimates of net clinical benefit. Read More

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A meta-analysis of clinical risk factors for stroke in anticoagulant-naïve patients with atrial fibrillation.

Europace 2021 Jul 19. Epub 2021 Jul 19.

Centre for Heart Rhythm Disorders, University of Adelaide, Adelaide, SA, Australia.

Aims: The aim of this study is to summarize data from prospective cohort studies on clinical predictors of stroke and systemic embolism in anticoagulant-naïve atrial fibrillation (AF) patients.

Methods And Results: EMBASE, MEDLINE, Global Index Medicus, and Web of Science were searched to identify all studies published by 28 November 2019. Forty-seven studies reporting data from 1 756 984 participants in 15 countries were included. Read More

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Chinese Herbal Medicine for Treating Epilepsy.

Front Neurosci 2021 2;15:682821. Epub 2021 Jul 2.

Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan.

Chinese herbal medicine has a long history of use for treating epilepsy. Because of the side effects of Western antiepileptic therapy and the quest for more accessible treatment, complementary and alternative medicines have become popular. Traditional Chinese medical diet therapy appears to be safe and effective. Read More

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Systematic review with meta-analysis: effects of implementing a nutrition support team for in-hospital parenteral nutrition.

Aliment Pharmacol Ther 2021 Jul 18. Epub 2021 Jul 18.

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Background: Nutrition support teams (NST) may improve parenteral nutrition (PN) outcomes. No previous systematic review has provided conclusive data on catheter-related infection (CRI) occurrence after NST introduction, nor have previous studies performed meta-analysis or graded the evidence.

Aims: To systematically evaluate the effects of implementing an NST for hospitalised adults on PN and compare these with standard care. Read More

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Residential radon exposure and leukemia: A meta-analysis and dose-response meta-analyses for ecological, case-control, and cohort studies.

Environ Res 2021 Jul 16;202:111714. Epub 2021 Jul 16.

Department of Environmental Health Science, Graduate School of Public Health, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul, 08826, Republic of Korea.

Introduction: In this study, the authors conducted a comprehensive systematic review and meta-analysis (including a dose-response meta-analysis) for a possible causal association between residential radon exposure and leukemia. All 3 types of study design, including ecological, case-control, and cohort studies, were included in this study. In particular, different measurement units of radon exposure among studies were dealt with and analyzed thoroughly. Read More

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Indirect Comparison of Topiramate and Monoclonal Antibodies Against CGRP or Its Receptor for the Prophylaxis of Episodic Migraine: A Systematic Review with Meta-Analysis.

CNS Drugs 2021 Jul 16. Epub 2021 Jul 16.

Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Charitéplatz 1 (Bonhoeffer-Weg 3), 10117, Berlin, Germany.

Background: Head-to-head comparator trials between first-line oral migraine preventatives and the new monoclonal antibodies (mAbs) blocking the calcitonin gene-related peptide (CGRP) pathway have not been published to date.

Objectives: This study aimed to indirectly compare the clinical efficacy and safety of mAbs against CGRP or its receptor (CGRPR) and topiramate in episodic migraine prophylaxis using meta-analysis.

Methods: We included controlled trials testing efficacy and safety of erenumab, galcanezumab, fremanezumab, eptinezumab, and topiramate in adults diagnosed with episodic migraine. Read More

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What is the incidence of medical device-related pressure injuries in adults within the acute hospital setting? A systematic review.

J Tissue Viability 2021 Mar 29. Epub 2021 Mar 29.

School of Nursing and Midwifery, Royal College of Surgeons in Ireland (RCSI), University of Medicine and Science, Ireland; Skin Wounds and Trauma Research Centre, RCSI, Ireland.

Medical devices provide effective therapeutic care for patients. However, medical device-related pressure injuries (MDRPI) are caused by prolonged pressure or shear from a medical device on any location on the body, including mucosal cavities. The primary outcome of this quantitative systematic review was to identify the incidence of MDRPIs in adults within the acute hospital setting. Read More

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