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The comparative histologic effects of subthreshold 532- and 810-nm diode micropulse laser on the retina.

Invest Ophthalmol Vis Sci 2013 Mar 1;54(3):2216-24. Epub 2013 Mar 1.

University of California-Davis, Department of Ophthalmology and Vision Science, Sacramento, California, USA.

Purpose: Therapeutic retinal laser photocoagulation can damage the neurosensory retina and cause iatrogenic visual impairment. Subthreshold micropulse photocoagulation may decrease this risk by selective tissue treatment. The aim of this study was to compare subthreshold 810-nm diode micropulse laser and subthreshold 532-nm micropulse laser on the retina by histologic examination and differential protein expression. Read More

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CXCR4/SDF-1 pathway is crucial for TLR9 agonist enhanced metastasis of human lung cancer cell.

Biochem Biophys Res Commun 2009 May 18;382(3):571-6. Epub 2009 Mar 18.

Department of Immunology, Zunyi Medical College, Guizhou, PR China.

Accumulating data suggested that CXCR4/SDF-1 pathway may play an important role in the metastasis of tumor. We previously demonstrated that CpG ODN could enhance the metastasis of human lung cancer cell via TLR9. Here we further evaluated the possible role of CXCR4/SDF-1 pathway in the enhanced metastasis of human lung cancer 95D cells induced by CpG ODN. Read More

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