Anesthesiology 2016 Jul;125(1):92-104
From the Department of Anesthesia, Critical Care and Pain Medicine (S.Z., C.H.S., S.A.M., S.D.G., T.M., D.D-.G., M.E.), Department of Surgery (M.M.H.), and Respiratory Care, Department of Anesthesia, Critical Care and Pain Medicine (D.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Sleep Medicine, Department of Neurology, Rheinische Friedrich-Wilhelms-University, Bonn, Germany (S.Z.); German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Bonn, Germany (S.Z.); Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (S.K.R.); Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Diego, La Jolla, California (A.M.); and Department of Anesthesia and Critical Care, University Hospital Essen, Essen, Germany (M.E.).
Background: Bariatric surgery patients are vulnerable to sleep-disordered breathing (SDB) early after recovery from surgery and anesthesia. The authors hypothesized that continuous positive airway pressure (CPAP) improves postoperative oxygenation and SDB and mitigates opioid-induced respiratory depression.
Methods: In a randomized crossover trial, patients after bariatric surgery received 30% oxygen in the postanesthesia care unit (PACU) under two conditions: atmospheric pressure and CPAP (8 to 10 cm H2O). Read More