123 results match your criteria scores wms-iii

Visuospatial short-term and working memory disturbance in the primary progressive aphasias: Neuroanatomical and clinical implications.

Cortex 2020 11 8;132:223-237. Epub 2020 Sep 8.

The University of Sydney, School of Psychology, Sydney, Australia; The University of Sydney, Brain and Mind Centre, Sydney, Australia. Electronic address:

Introduction: Primary progressive aphasia (PPA) comprises three main variants: logopenic (lv-PPA), non-fluent (nfv-PPA) and semantic variant (sv-PPA). Differentiating the language profiles of the PPA variants remains challenging, especially for lv-PPA and nfv-PPA. As such, diagnostic tools that do not rely on speech and language may offer some utility. Read More

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November 2020

Attention/Working Memory, Learning and Memory in Adult Cameroonians: Normative Data, Effects of HIV Infection and Viral Genotype.

J Int Neuropsychol Soc 2020 07 18;26(6):607-623. Epub 2020 Feb 18.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA92093, USA.

Objective: There is lack of Cameroonian adult neuropsychological (NP) norms, limited knowledge concerning HIV-associated neurocognitive disorders in Sub-Saharan Africa, and evidence of differential inflammation and disease progression based on viral subtypes. In this study, we developed demographically corrected norms and assessed HIV and viral genotypes effects on attention/working memory (WM), learning, and memory.

Method: We administered two tests of attention/WM [Paced Auditory Serial Addition Test (PASAT)-50, Wechsler Memory Scale (WMS)-III Spatial Span] and two tests of learning and memory [Brief Visuospatial Memory Test-Revised (BVMT-R), Hopkins Verbal Learning Test-Revised (HVLT-R)] to 347 HIV+ and 395 seronegative adult Cameroonians. Read More

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Association between polymorphism of the NEDD4 gene and cognitive dysfunction of schizophrenia patients in Chinese Han population.

BMC Psychiatry 2019 12 18;19(1):405. Epub 2019 Dec 18.

Shandong Mental Health Center, Jinan, Shandong, People's Republic of China.

Background: Schizophrenia is a complex psychiatric disorder with unknown etiology. A number of recent studies have shown that the polymorphism of the neural precursor cell expressed developmentally down-regulated 4 (NEDD4) gene is associated with a variety of neuropsychiatric disorders, such as schizophrenia, and may also be associated with cognitive dysfunction in these diseases.

Methods: A case-control study was carried out, the alleles and genotypes distributions of five loci (rs3088077, rs2303579, rs7162435, rs11550869, rs62043855) of the NEDD4 gene from 296 schizophrenia patients and 320 healthy controls were detected by using Taqman single-nucleotide polymorphism (SNP) genotyping technology. Read More

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December 2019

Polymorphism in the LASP1 gene promoter region alters cognitive functions of patients with schizophrenia.

Sci Rep 2019 12 11;9(1):18840. Epub 2019 Dec 11.

Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.

Schizophrenia's pathogenesis remains elusive. Cognitive dysfunction is the endophenotype and outcome predictor of schizophrenia. The LIM and SH3 domain protein (LASP1) protein, a component of CNS synapses and dendritic spines, has been related to the N-methyl-D-aspartate receptor (NMDAR) dysfunction hypothesis and schizophrenia. Read More

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December 2019

Recognition of Famous and Unfamiliar Faces among Patients Suffering from Amnesia Mild Cognitive Impairment (AMCI) and Alzheimer's Disease.

Iran J Psychiatry 2019 Jul;14(3):227-235

Neuropsychological Assessments in Mehr Clinic, Shiraz, Iran.

Memory assessment for the early diagnosis of cortical dementia is a complicated process which depends on important factors such as facial recognition and naming. These factors could be considered to carry a predictive power to detect neurodegenerative disorders. The present study aimed to study and compare naming or recognizing famous faces with the recognition of newly learned faces among patients with Amnesia Mild Cognitive Impairment (AMCI) and Alzheimer's disease. Read More

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Episodic memory and executive functioning in informal dementia caregivers.

Aging Ment Health 2020 10 22;24(10):1681-1689. Epub 2019 May 22.

Department of Cognitive Neuropsychology, Tilburg University, Tilburg, The Netherlands.

Informal dementia caregivers are thought to experience high levels of depression and burden, which can contribute to worse cognitive functioning. However, poorer cognitive functioning in caregivers is not always found. The current study explored whether caregivers perform better, worse, or similar to non-caregivers on tasks for executive functioning and memory. Read More

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October 2020

The Effects of Radiation and Sex Differences on Adaptive Functioning in Adult Survivors of Pediatric Posterior Fossa Brain Tumors.

J Int Neuropsychol Soc 2019 08;25(7):729-739

Department of Psychology, Georgia State University, Atlanta, GA, USA.

Objective: Radiation therapy (RT) improves rates of survival of patients with childhood brain tumors but increases deficits in cognition and independent living skills. Previous literature has studied difficulties in basic cognitive processes, but few explore impairment in higher-order skills such as adaptive functioning. Some studies identify females as at risk for cognitive deficits due to RT, but few investigate sex differences in adaptive functioning. Read More

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Memory Impairment and Plasma BDNF Correlates of the Polymorphism in Patients With Bipolar II Disorder.

Front Genet 2018 27;9:583. Epub 2018 Nov 27.

Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Studies suggest that a functional polymorphism of brain-derived neurotrophic factor (BDNF), polymorphism affects cognitive functions, however, the effect is unclear in bipolar II (BD-II) disorder. We used the Wechsler Memory Scale-third edition (WMS-III), the presence of the polymorphism, and plasma concentrations of BDNF to investigate the association between memory impairment and BDNF in BD-II disorder. We assessed the memory functions of 228 BD-II patients and 135 healthy controls (HCs). Read More

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November 2018

Trajectories of brain development in school-age children born preterm with very low birth weight.

Sci Rep 2018 10 22;8(1):15553. Epub 2018 Oct 22.

Department of Clinical & Molecular Medicine, Norwegian University of Science & Technology, Trondheim, Norway.

Preterm birth (gestational age < 37 weeks) with very low birth weight (VLBW, birth weight ≤ 1500 g) is associated with lifelong cognitive deficits, including in executive function, and persistent alterations in cortical and subcortical structures. However, it remains unclear whether "catch-up" growth is possible in the preterm/VLBW brain. Longitudinal structural MRI was conducted with children born preterm with VLBW (n = 41) and term-born peers participating in the Norwegian Mother and Child Cohort Study (MoBa) (n = 128) at two timepoints in early school age (mean ages 8. Read More

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October 2018

Psychometric properties and reference data for Danish versions of Free and Cued Selective Reminding Test, Category Cued Memory Test and Logical Memory.

Scand J Psychol 2018 Oct 12;59(5):496-502. Epub 2018 Jul 12.

Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Memory assessment is a key element in neuropsychological testing. Gold standard evaluation is based on updated normative data, but in many small countries (e.g. Read More

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October 2018

Evaluation of diffusion tensor imaging changes and neurocognitive effects of asymptomatic vitamin B12 deficiency.

Acta Neurol Belg 2018 Jun 16;118(2):289-296. Epub 2018 Apr 16.

Department of Radiology, Adiyaman University Faculty of Medicine, Siteler Mahallesi, Atatürk Bulvarı, No. 411, Adiyaman, Turkey.

Vitamin B12 plays an important role in the mechanisms which are responsible for myelinization in the central nervous system. It can particularly lead to hematological and neuropsychiatric symptoms when serum levels fall due to insufficient intake with diet or absorption problems. The purpose of this study was to show the cognitive effects in vitamin B12 deficiency cases that have not reached clinical symptom level using neuropsychological tests, and to show possible cerebral neuronal damage using diffusion tensor imaging (DTI) method. Read More

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Temporal lobe thickness and verbal memory in first-degree relatives of individuals with schizophrenia.

Schizophr Res 2018 09 28;199:221-225. Epub 2018 Feb 28.

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, Geffen School of Medicine at UCLA, Los Angeles, CA, United States; Department of Psychology, UCLA, Los Angeles, CA, United States. Electronic address:

Cortical thinning in frontal and temporal regions has been reported in individuals diagnosed with schizophrenia and, less consistently, among their unaffected first-degree relatives. Likewise, first-degree relatives demonstrate attenuated differences in neurocognitive performance relative to healthy controls, indicating that neurocognitive performance may be an important endophenotype of the disorder. Less is known about how cortical thickness relates to neurocognitive performance in these individuals. Read More

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September 2018

Blood Alcohol Concentration-Related Lower Performance in Immediate Visual Memory and Working Memory in Adolescent Binge Drinkers.

Front Psychol 2017 4;8:1720. Epub 2017 Oct 4.

Department of Psychobiology, University of Valencia, Valencia, Spain.

The binge drinking (BD) pattern of alcohol consumption is prevalent during adolescence, a period characterized by critical changes to the structural and functional development of brain areas related with memory and cognition. There is considerable evidence of the cognitive dysfunctions caused by the neurotoxic effects of BD in the not-yet-adult brain. Thus, the aim of the present study was to evaluate the effects of different blood alcohol concentrations (BAC) on memory during late adolescence (18-19 years old) in males and females with a history of BD. Read More

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October 2017

Investigating patterns of memory impairment in ischemic stroke in an iranian population.

Appl Neuropsychol Adult 2018 Sep-Oct;25(5):458-463. Epub 2017 Sep 7.

b Department of Neurology , Isfahan University of Medical Sciences , Isfahan , Iran.

Up until the date of this research, studies have examined poststroke cognitive impairments in attention, memory, and executive functions. In this study, we investigated the occurrence of memory problems in various patterns of memory in ischemic stroke patients in an attempt to determine specific memory profiles of the patients. The goal was to determine the severity and patterns of memory impairments in ischemic stroke patients and to identify specific profiles of memory impairments in stroke patients, in order to help therapists to develop more appropriate memory rehabilitation programs for the patients. Read More

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October 2018

Depression, inflammation, and memory loss among Mexican Americans: analysis of the HABLE cohort.

Int Psychogeriatr 2017 10 20;29(10):1693-1699. Epub 2017 Jun 20.

Center for Neuroscience Discovery,University of North Texas Health Science Center,Fort Worth,Texas,USA.

Background: This study explored the combined impact of depression and inflammation on memory functioning among Mexican-American adults and elders.

Methods: Data were analyzed from 381 participants of the Health and Aging Brain study among Latino Elders (HABLE). Fasting serum samples were collected and assayed in duplicate using electrochemiluminesce on the SECTOR Imager 2400A from Meso Scale Discovery. Read More

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October 2017

Comparison of Two Measures of Working Memory Impairments in 220 Adolescents and Adults With ADHD.

J Atten Disord 2019 Dec 1;23(14):1838-1843. Epub 2016 Aug 1.

Keck School of Medicine of University of Southern California, Los Angeles, USA.

This study tests the hypotheses that (a) adolescents and adults with ADHD score lower on two normed measures of verbal working memory, relative to their overall verbal abilities, than the general population and (b) a specific story memory test is a more sensitive and relevant measure of working memory impairment than a numerically based test. Scores on normed story memory and numerical memory tests of 220 adolescents and adults with ADHD were corrected for the individual's verbal abilities and compared with each other and national norms. Participants with ADHD scored significantly below their verbal ability measure on both verbal and numerically based memory tests in comparison with national norms. Read More

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December 2019

Catechol-O-methyltransferase val(158)met Polymorphism Interacts with Sex to Affect Face Recognition Ability.

Front Psychol 2016 27;7:965. Epub 2016 Jun 27.

School of Psychology, The University of Auckland Auckland, New Zealand.

The catechol-O-methyltransferase (COMT) val158met polymorphism affects the breakdown of synaptic dopamine. Consequently, this polymorphism has been associated with a variety of neurophysiological and behavioral outcomes. Some of the effects have been found to be sex-specific and it appears estrogen may act to down-regulate the activity of the COMT enzyme. Read More

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Portuguese version of Wechsler Memory Scale-3rd edition's utility with demented elderly adults.

Appl Neuropsychol Adult 2017 May-Jun;24(3):212-225. Epub 2016 Apr 18.

d Neurology Department , Baixo Vouga Hospital Center , Aveiro , Portugal.

The purpose of this study is to analyze the utility of the Portuguese version of the Wechsler Memory Scale-3rd edition (WMS-III) with demented elderly people, namely its capacity to detect and discriminate between subcortical vascular dementia (SVD) and Alzheimer's disease (AD). We assessed early demented patients (SVD = 16; AD = 36) aged 65 or older who were compared to a control group (n = 40). Both clinical groups were adequately matched in terms of disease severity, overall cognitive functioning, depressive symptomatology, and pre-morbid intelligence. Read More

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Contralateral ictal electrographic involvement is associated with decreased memory performance in unilateral mesial temporal sclerosis.

J Neurol Sci 2015 12 5;359(1-2):241-6. Epub 2015 Nov 5.

Department of Neurology, Faculdade de Medicina Universidade de Sao Paulo, Sao Paulo, Brazil.

Purpose: To evaluate the effect of contralateral electrographic involvement on memory performance (measured by neuropsychological and Wada memory testing) in patients with epilepsy associated with unilateral mesial temporal sclerosis (MTS).

Methods: We studied 51 patients with medically-refractory epilepsy associated with unilateral MTS (27 women, 30/51, left MTS) submitted to prolonged non-invasive video-EEG monitoring and bilateral Wada testing. According to ictal electrographic involvement, patients were classified as: Contralateral ictal involvement, when one or more seizures evolved with rhythmic activity in the temporal region contralateral to the MTS or exclusive ipsilateral ictal involvement if all seizures showed ictal EEG activity exclusively on the MTS side. Read More

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December 2015

A Confirmatory Factor Analytic Study of the Wechsler Memory Scale-III in an Elderly Norwegian Sample.

Arch Clin Neuropsychol 2016 Feb 21;31(1):12-7. Epub 2015 Oct 21.

Department of Psychosocial Science, University of Bergen, Bergen, Norway.

This study compared the factor structure of the translated Wechsler Memory Scale-III (WMS-III), which is the latest available version in Norway, with the original U.S. version. Read More

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February 2016

The brain-derived neurotrophic factor (BDNF) val66met polymorphism differentially affects performance on subscales of the Wechsler Memory Scale - Third Edition (WMS-III).

Front Psychol 2015 17;6:1212. Epub 2015 Aug 17.

School of Psychology, Faculty of Science, The University of Auckland, Auckland New Zealand.

Single nucleotide polymorphisms in the brain-derived neurotrophic factor (BDNF) gene and the catechol-O-methyltransferase (COMT) gene influence brain structure and function, as well as cognitive abilities. They are most influential in the hippocampus and prefrontal cortex (PFC), respectively. Recall and recognition are forms of memory proposed to have different neural substrates, with recall having a greater dependence on the PFC and hippocampus. Read More

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September 2015

Evoked Potentials and Memory/Cognition Tests Validate Brain Atrophy as Measured by 3T MRI (NeuroQuant) in Cognitively Impaired Patients.

PLoS One 2015 5;10(8):e0133609. Epub 2015 Aug 5.

Department of Psychiatry, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida, United States of America.

To our knowledge, this is the largest study evaluating relationships between 3T Magnetic Resonance Imaging (MRI) and P300 and memory/cognitive tests in the literature. The 3T MRI using NeuroQuant has an increased resolution 15 times that of 1.5T MRI. Read More

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Toward the processing speed theory of activities of daily living in healthy aging: normative data of the Functional Activities Questionnaire.

Aging Clin Exp Res 2016 Apr 1;28(2):239-47. Epub 2015 Aug 1.

National Institute of Mental Health, Klecany, Czech Republic.

Background: The aim of this study was to describe an instrumental activities of daily living (IADL) measure: Functional Activities Questionnaire (FAQ), which is often used in clinical settings as a self- or informant-based measure of IADL. However, the FAQ's relationship with age or education in healthy aging has not been investigated.

Methods: FAQ and a neuropsychological battery were administered to old and very old Czech adults (n = 540). Read More

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Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls.

Acta Psychiatr Scand 2016 Jan 20;133(1):53-62. Epub 2015 Jul 20.

NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Objective: We investigated whether elevated plasma levels of immune markers were associated with verbal memory and hippocampal subfield volumes in patients with severe mental illnesses and in healthy controls.

Method: In total, 230 patients with a broad DSM-IV schizophrenia spectrum illness or bipolar disorder and 236 healthy controls were recruited. Memory was assessed using the Wechsler Memory Scale-Third Edition (WMS-III) Logical Memory immediate and delayed recall, and the California Verbal Learning Test summed recall over learning list (CVLT learning) and delayed free recall. Read More

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January 2016

Combined effects of marijuana and nicotine on memory performance and hippocampal volume.

Behav Brain Res 2015 Oct 14;293:46-53. Epub 2015 Jul 14.

The Center for BrainHealth, School of Behavioral and Brain Sciences, University of Texas at Dallas, United States.

Combined use of marijuana (MJ) and tobacco is highly prevalent in today's population. Individual use of either substance is linked to structural brain changes and altered cognitive function, especially with consistent reports of hippocampal volume deficits and poorer memory performance. However, the combined effects of MJ and tobacco on hippocampal structure and on learning and memory processes remain unknown. Read More

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October 2015

Working memory impairment in probands with schizoaffective disorder and first degree relatives of schizophrenia probands extend beyond deficits predicted by generalized neuropsychological impairment.

Schizophr Res 2015 Aug 23;166(1-3):310-5. Epub 2015 May 23.

Department of Psychiatry, University of Texas Southwestern, Dallas, TX, United States.

Objective: Working memory impairment is well established in psychotic disorders. However, the relative magnitude, diagnostic specificity, familiality pattern, and degree of independence from generalized cognitive deficits across psychotic disorders remain unclear.

Method: Participants from the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study included probands with schizophrenia (N=289), psychotic bipolar disorder (N=227), schizoaffective disorder (N=165), their first-degree relatives (N=315, N=259, N=193, respectively), and healthy controls (N=289). Read More

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Evaluating the impact of hippocampal sparing during whole brain radiotherapy on neurocognitive functions: A preliminary report of a prospective phase II study.

Biomed J 2015 Sep-Oct;38(5):439-49

Department of Neurosurgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Whole brain radiotherapy (WBRT) is the treatment of choice for patients with brain metastases. However, neurocognitive functions (NCFs) decline due to impaired hippocampal neurogenesis might occur thereafter. It is hypothesized that conformal hippocampal avoidance during the course of WBRT (HA-WBRT) might provide meaningful NCF preservation. Read More

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December 2016

A pilot study on utility of Malayalam version of Addenbrooke's Cognitive Examination in detection of amnestic mild cognitive impairment: A critical insight into utility of learning and recall measures.

Ann Indian Acad Neurol 2014 Oct;17(4):420-5

Department of Neurology, Cognitive and Behavioural Neurology Section, National Institute for Mental Health and Neuro Sciences, Bangalore, Karnataka, India.

Aims: This pilot study sought to determine whether the Malayalam adaptation of Addenbrooke's Cognitive Examination (M-ACE) can effectively identify patients with amnestic mild cognitive impairment (a-MCI) and the impact of measures of learning and free recall.

Materials And Methods: A cohort of 23 patients with a-MCI aged between 55-80 years diagnosed as per current criteria and 23 group matched cognitively normal healthy controls (CNHC) were studied. The measures of acquisition and delayed recall were the Rey Auditory Verbal Learning Test (RAVLT) and Wechsler Memory Scale (WMS)-III (verbal and visual subsets) and Delayed Matching-to-sample Test (DMS)-48. Read More

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October 2014

Predictors of memory and processing speed dysfunctions after traumatic brain injury.

Biomed Res Int 2014 29;2014:129796. Epub 2014 Apr 29.

Department of Occupational Therapy, College of Health Sciences, Kaohsiung Medical University, Kaohsiung City 807, Taiwan.

Background: The aims of this study were to evaluate the predictive value of admission Glasgow Coma Scale (GCS) scores, duration of unconsciousness, neurosurgical intervention, and countercoup lesion on the impairment of memory and processing speed functions six months after a traumatic brain injury (TBI) based on a structural equation modeling.

Methods: Thirty TBI patients recruited from Neurosurgical Department at the Kaohsiung Medical University Hospital were administered the Wechsler Memory Scale-III (WMS-III) and the Wechsler Adult Intelligence Scale-III processing speed index to evaluate the memory and processing speed functions.

Results: The study showed that GCS scores accounted for 40% of the variance in memory/processing speed. Read More

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February 2015

Does brain volume loss predict cognitive and narrative discourse performance following traumatic brain injury?

Am J Speech Lang Pathol 2014 May;23(2):S271-84

Purpose: In this study, the authors investigated the relationship between brain volume loss and performance on cognitive measures, including working memory, immediate memory, executive functions, and intelligence, and a narrative discourse production task. An underlying goal was to examine the prognostic potential of a brain lesion metric for discourse outcomes. It was hypothesized that brain volume loss would correlate with and predict cognitive and narrative discourse measures and have prognostic value for discourse outcomes. Read More

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