23,936 results match your criteria scleral

The history of pneumatic retinopexy: have we come full circle?

Acta Ophthalmol 2021 Apr 14. Epub 2021 Apr 14.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

The historical literature on the treatment of rhegmatogenous retinal detachment (RRD) was reviewed from 1911 to the present, focusing on the role of intravitreal air and gas. The history of the pneumatic retinopexy (PnR) technique is described from its original roots to the current day procedure. The treatment of RRD has evolved tremendously over the past century. Read More

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Poor Outcome in Camel-Related Eye Trauma with Ruptured Globe.

Int Med Case Rep J 2021 7;14:219-222. Epub 2021 Apr 7.

Department of Ophthalmology, Tabuk University, Tabuk, Saudi Arabia.

Purpose: To report the poor visual outcome of ruptured globe caused by camel bites.

Observations: A 48-year-old camel caregiver presented to the emergency department after being bitten by a camel in the left side of his face. Ophthalmic examination revealed a superior scleral wound from 9 to 2 o'clock, about 6 mm from the limbus extending to the equator with prolapse of uveal and vitreous tissues, an opaque cornea, total hyphema, diffuse subconjunctival hemorrhage, and a lower lid laceration involving the lid margin and the nasolacrimal duct. Read More

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Safety and Efficacy of Current Sclera Fixation Methods for Intraocular Lenses and Literature Overview.

Klin Monbl Augenheilkd 2021 Apr 14. Epub 2021 Apr 14.

Augenklinik und Poliklinik, Klinikum der Universität München, LMU München, Deutschland.

Background: Evaluation of the three currently most common techniques for intraocular lens (IOL) sclera fixation: (1) Prolene suture with Hoffman sclera pocket (2) four-point GoreTex suture technique (3) sutureless flanged intrascleral IOL fixation with double-needle ("Yamane") technique.

Material And Methods: Retrospective, clinical case series (chart review) at the Department of Ophthalmology, Ludwig-Maximilians-University (LMU), Munich, Germany. Enrolled in the study were 51 patients with 55 eyes. Read More

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Am J Ophthalmol 2021 Apr 11. Epub 2021 Apr 11.

Department of Computer Science, University of California, Irvine.

Purpose: To improve the apparent motility of ocular prosthetic devices using technology. Prevailing ocular prostheses are acrylic shells with a static eye image rendered on the convex surface. A limited range of ocular prosthetic movement and lack of natural saccadic movements commonly causes the appearance of eye misalignment that may be disfiguring. Read More

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Decreased choroidal and scleral thicknesses in highly myopic eyes with posterior staphyloma.

Sci Rep 2021 Apr 12;11(1):7987. Epub 2021 Apr 12.

Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Korea.

In this cross-sectional study, we investigated choroidal thickness (CT) and scleral thickness (ST) in highly myopic eyes and their associations with ocular factors. Patients underwent widefield swept-source optical coherence tomography (OCT) to measure the CT and ST at the subfovea and 3000 μm superior, inferior, temporal, and nasal to the fovea and macular curvature. A total of 237 eyes (154 patients) were included. Read More

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Towards 'automated gonioscopy': a deep learning algorithm for 360° angle assessment by swept-source optical coherence tomography.

Br J Ophthalmol 2021 Apr 12. Epub 2021 Apr 12.

Singapore Eye Research Institute/Singapore National Eye Centre, Singapore

Aims: To validate a deep learning (DL) algorithm (DLA) for 360° angle assessment on swept-source optical coherence tomography (SS-OCT) (CASIA SS-1000, Tomey Corporation, Nagoya, Japan).

Methods: This was a reliability analysis from a cross-sectional study. An independent test set of 39 936 SS-OCT scans from 312 phakic subjects (128 SS-OCT meridional scans per eye) was analysed. Read More

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Central-to-peripheral corneal edema during wear of embedded-component contact lenses.

Cont Lens Anterior Eye 2021 Apr 9:101443. Epub 2021 Apr 9.

Vision Science Group, University of California, Berkeley, CA, 94720, United States; Chemical and Biomolecular Engineering Department, University of California, Berkeley, CA, 94720, United States. Electronic address:

Purpose: With active investigation underway for embedded-circuit contact lenses, safe oxygen supply of these novel lenses remains a question. Central-to-peripheral corneal edema for healthy eyes during wear of soft contact (SCL) and scleral lenses (SL) with embedding components is assessed.

Methods: Various 2-dimensional (2D) designs of SL and SCL with embedded components are constructed on Comsol Multiphysics 5. Read More

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Observed Frequency and Characteristics of Hearing Loss in Osteogenesis Imperfecta.

Rev Med Chil 2020 Dec;148(12):1781-1786

Department of Pediatric Endocrinology, UC Christus Health Center, Pontificia Universidad Católica de Chile, Chile.

Background: Osteogenesis imperfecta (OI) is a rare group of genetic disorders affecting connective tissue, with consequent bone fragility, frequent fractures and skeletal deformity. Depending on the type, patients can have blue sclera, dentinogenesis imperfecta, and hearing loss.

Aim: To determine the frequency, type and audiometric characteristics of hearing loss in a group of patients with OI. Read More

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December 2020

Modified illuminated scleral depressor: A cost-efficient instrument for unassisted vitreous base shaving.

Retina 2021 Apr 2. Epub 2021 Apr 2.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Port Road, SA 5000, Australia.

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Pediatric rhegmatogenous retinal detachment: predictors of anatomic and functional success.

Int Ophthalmol 2021 Apr 11. Epub 2021 Apr 11.

Instituto de Oftalmología Conde de Valenciana IAP, Mexico City, Mexico.

Purpose: This study describes presenting clinical features and surgical techniques associated with successful repair of pediatric rhegmatogenous retinal detachment (RRD).

Methods: This is a retrospective case series which involved 242 cases younger than 18 years with new-onset RRD with descriptive statistics for the full group. Further exclusion established 168 cases that underwent surgery with minimum 3-month follow-up. Read More

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Long-term ocular biometric variations after scleral buckling surgery in macula-on rhegmatogenous retinal detachment.

BMC Ophthalmol 2021 Apr 10;21(1):172. Epub 2021 Apr 10.

Ophthalmology Unit - Department of Sense Organs, Sapienza University of Rome - Policlinico Umberto I University Hospital, Rome, Italy.

Background: Myopic shift and biometric ocular changes have been previously observed after scleral buckling (SB) surgery in rhegmatogenous retinal detachment (RRD), but long term-term outcomes had not yet been explored. The purpose of present study is to evaluate long term ocular biometric changes in patients with primary macula-on RRD treated with SB.

Methods: In this retrospective, observational study, we reviewed the medical records of patients undergoing SB surgery for macula-on RRD. Read More

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Computer-aided Intraoperative Toric Intraocular Lens Positioning and Alignment During Cataract Surgery.

IEEE J Biomed Health Inform 2021 Apr 9;PP. Epub 2021 Apr 9.

Cataract causes more than half of all blindness worldwide. The most effective treatment is surgery, where cataract is often replaced by intraocular lens (IOL). Beyond saving vision, toric IOL implantation is becoming increasingly popular to correct corneal astigmatism. Read More

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Asymptomatic epiploic appendage with torsion in laparoscopic surgery: a case report and literature review.

Ann Palliat Med 2021 Apr 1. Epub 2021 Apr 1.

Department of General Surgery, Strategic Support Force Medical Center, Beijing, China.

Torsion of an epiploic appendage may result in epiploic appendagitis, which is a rare cause of acute abdominal pain. However, no previous reports have described an asymptomatic twisted epiploic appendage found during laparoscopic surgery to the best of our knowledge. This case describes a 66-year-old man who was admitted to our medical center with yellowness of the skin and eyes that had lasted over two months. Read More

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Bandage lens for treatment of corneosclera melting two weeks after pterygium surgery: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25348

Eye Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, China.

Introduction: Pterygium is a common chronic ocular surface condition in ophthalmology.At present, the main treatment modality is surgical resection. Although the recurrence rate can be controlled to varying degrees, some patients can still develop serious complications, such as scleral melting, corneal melting, and even corneal perforation. Read More

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[Regulation of bFGF and TGF-β2 in human scleral fibroblasts by the lumican gene mutation associated with myopia].

Zhonghua Yan Ke Za Zhi 2021 Apr;57(4):277-283

Beijing Tongren Eye Center, Beijing Tongren Hospital of Capital Medical University, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.

To investigate the regulation of basic fibroblast growth factor (bFGF) and transforming growth factor (TGF)-β2 in human scleral fibroblasts (HSFs) by the adenovirus-mediated Lumican gene mutation, and to illustrate the effect of this mutation on myopia. Experimental study. The HSFs were isolated and cultured from human scleral tissues. Read More

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Infectious Scleritis due to Methicillin-resistant Staphylococcus Aureus after Dengue Viral Fever.

Ocul Immunol Inflamm 2021 Apr 8:1-3. Epub 2021 Apr 8.

Cornea Service, The Cornea Institute, L V Prasad Eye Institute, Hyderabad, India.

: Dengue fever is a severe mosquito-borne disease which can present with various severe ocular manifestations. We aim to report a case of infectious scleritis in dengue fever, occurring due to Methicillin-resistant Staphylococcus aureus (MRSA), managed with intravenous Teicoplanin.: Case report. Read More

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Refractive outcome of trocar-assisted sutureless scleral fixation with 3-piece intraocular lenses.

Int Ophthalmol 2021 Apr 7. Epub 2021 Apr 7.

Department of Ophthalmology, Faculty of Medicine, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Kadikoy, Istanbul, Turkey.

Purpose: Intraocular lens (IOL) implantation with a trocar-assisted sutureless scleral fixation technique is a relatively new IOL implantation approach for aphakic eyes. During this surgery, the intrascleral position of the haptics can change the location of the IOL optic and may alter the refractive outcome. This study aimed to evaluate the refractive outcome of this surgery. Read More

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Multifocal Electroretinogram in Keratoconus Patients without and with Scleral Lenses.

Curr Eye Res 2021 Apr 7. Epub 2021 Apr 7.

Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics, University of Minho. Braga Portugal.

: To investigate changes in the multifocal electroretinogram (mfERG) response in eyes with keratoconus when corrected with scleral lenses (SL) compared with the best correction in glasses.: The mfERG response s in 10 eyes with keratoconus were recorded with the best correction using both a trial frame (baseline) and a hexafocon A SL using an electrophysiological diagnostic system. Electrophysiologic measurements were performed with the pupils fully dilated with instillation of 1% phenylephrine. Read More

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Adaptive Control Improves Sclera Force Safety in Robot-Assisted Eye Surgery: A Clinical Study.

IEEE Trans Biomed Eng 2021 Apr 6;PP. Epub 2021 Apr 6.

The integration of robotics into retinal microsurgery leads to a reduction in surgeon perception of tool-to-tissue interaction forces. Tool shaft-to-sclera, and tool tip-to-surgical target, forces are rendered either markedly reduced or imperceptible to the surgeon. This blunting of human tactile sensory input is due to the inflexible mass and large inertia of the robotic arm as compared to the milli-Newton scale of the interaction forces encountered during ophthalmic surgery. Read More

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Wegener's granulomatosis with orbital involvement: case report and literature review.

Rom J Ophthalmol 2021 Jan-Mar;65(1):93-97

Emergency Eye Hospital, Bucharest, Romania.

To describe the chronology and the extent of orbital involvement in a case of granulomatosis with polyangiitis. Descriptive case report and literature review. A 45-year-old patient, formerly diagnosed with granulomatosis with polyangiitis due to otorhinolaryngologic manifestations, pulmonary lesions, renal impairment, left knee arthritis and high blood levels of antineutrophil cytoplasmic antibodies, addressed the Ophthalmology Department in November 2020, having the following complaints: left eye mild retro-orbital discomfort, proptosis and epiphora. Read More

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Retinal detachment following focal laser to ruptured retinal artery macro aneurysm.

Rom J Ophthalmol 2021 Jan-Mar;65(1):70-72

Smt. Kanuri Santhamma Centre for Vitreoretinal Diseases, LV Prasad Eye Institute, Hyderabad India.

A 53-year-old lady presented with inferior retinal detachment (RD) following focal laser for retinal artery macroaneurysm (RAM). She underwent focal laser with intravitreal gas injection elsewhere; however, no retinal break was localized on the examination. The patient was taken up for vitreoretinal surgery. Read More

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Superficial Temporal Muscle Fascia Grafting: Successful Transplant of Surgical-induced Necrotizing Scleritis.

Middle East Afr J Ophthalmol 2020 Oct-Dec;27(4):238-240. Epub 2021 Jan 19.

Institute Hedi Raies of Ophthalmology, Tunis, Tunisia.

To report the case of a surgical-induced necrotizing scleritis (SINS) following vitreoretinal surgery for rhegmatogenous retinal detachment, successfully managed by superficial muscle temporal fascia grafting. An 18-year-old teenager, with a history of a 23G vitrectomy with silicone oil tamponade for rhegmatogenous retinal detachment of the left eye, presented with intense left ocular pain, decreased visual acuity to counting fingers and eye redness. Split lamp examination showed: Conjunctival infiltration with silicone oil, circumferential sclera thinning with ectasia of the underling uvea. Read More

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January 2021

NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice.

Exp Cell Res 2021 Mar 31;403(1):112581. Epub 2021 Mar 31.

Department of Ophthalmology, School of Medicine, Sapporo Medical University, Sapporo, Japan.

Purpose: To evaluate Nuclear Factor NF-κB (NF-κB) signaling on microglia activation, migration, and angiogenesis in laser-induced choroidal neovascularization (CNV).

Methods: Nine-week-old C57BL/6 male mice were randomly assigned to IMD-0354 treated or untreated groups (5 mice, 10 eyes per group). CNV was induced with a 532-nm laser. Read More

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Lipid Peroxidation in Subretinal Fluid: Some Light on the Prognosis Factors.

Biomolecules 2021 Mar 30;11(4). Epub 2021 Mar 30.

Thematic Cooperative Health Network for Research in Ophthalmology (Oftared), Carlos III Health Institute, 28220 Madrid, Spain.

The aim of this study was to identify a relation between the clinical characteristics and differences in lipid peroxidation in the subretinal fluid (SRF) of rhegmatogenous retinal detached patients by malondialdehyde (MDA) quantification. We collected 65 SRF samples from consecutive patients during scleral buckling surgery in rhegmatogenous retinal detachment (RRD) eyes. In addition to a complete ophthalmic evaluation, we studied the refractive status, evolution time, and the number of detached retinal quadrants to establish the extension of RRD. Read More

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Investigating the Relationship between Glaucoma Prevalence and Trabecular Meshwork Length.

J Clin Med 2021 Mar 5;10(5). Epub 2021 Mar 5.

Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Korea.

Glaucoma is one of the most common causes of blindness worldwide, but the risk factors of glaucoma are yet to be fully understood. We investigated the relationship between the prevalence of glaucoma and trabecular meshwork (TM) length by comparing the mean TM length of a South Korean population with that of another ethnic population. We included 250 eyes of 125 patients who underwent anterior segment optical coherence tomography at Yonsei University Gangnam Severance Hospital between January 2015 and December 2017. Read More

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Relationship between Axial Length and Corneo-Scleral Topography: A Preliminary Study.

Diagnostics (Basel) 2021 Mar 18;11(3). Epub 2021 Mar 18.

Group of Optics and Visual Perception, Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 Alicante, Spain.

The main objective of the current study was to investigate further the relationship of the overall length of the eye with a great variety of anterior segment parameters, including scleral geometry. A total of 64 eyes of 32 participants with ages from 12 to 52 years were included in this prospective non-randomized single-center study. All participants underwent a complete eye examination, including an analysis of corneo-scleral shape with a Fourier-domain profilometer. Read More

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Intratumor Heterogeneity in Uveal Melanoma BAP-1 Expression.

Cancers (Basel) 2021 Mar 7;13(5). Epub 2021 Mar 7.

Departments of Ophthalmology and Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Malignant tumors are rarely homogenous on the morphological, genome, transcriptome or proteome level. In this study, we investigate the intratumor heterogeneity of BAP-1 expression in uveal melanoma with digital image analysis of 40 tumors. The proportion of BAP-1 positive cells was measured in full tumor sections, hot spots, cold spots and in scleral margins. Read More

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A Case Series of "Solitary Idiopathic Choroiditis" and Proposal of a Nomenclature Change to "Idiopathic Scleroma".

Ocul Oncol Pathol 2021 Mar 10;7(1):48-53. Epub 2020 Nov 10.

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Objective: To define the characteristics of solitary idiopathic choroiditis (SIC) in a consecutive series of patients and propose a nomenclature change to idiopathic scleroma.

Materials And Methods: Electronic patient records were retrospectively interrogated to identify all patients diagnosed with SIC between 2002 and 2019 in a tertiary referral ophthalmic hospital in the United Kingdom.

Results: Thirty-four eyes of 34 patients were found to have SIC. Read More

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Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis.

Ophthalmol Retina 2021 Mar 29. Epub 2021 Mar 29.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To assess visual acuity (VA) outcomes of epiretinal membrane (ERM) surgery following primary rhegmatogenous retinal detachment (RD) repair.

Design: Retrospective, consecutive case series.

Subjects: Eyes undergoing pars plana vitrectomy (PPV) with membrane peel (MP) surgery for ERM following primary RD repair (PPV with or without scleral buckle (SB) and gas tamponade). Read More

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Ophthalmic manifestations in Kabuki (make-up) syndrome: A single-center pediatric cohort and systematic review of the literature.

Eur J Med Genet 2021 Mar 29:104210. Epub 2021 Mar 29.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; The Institute for Rare Diseases, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel. Electronic address:

Kabuki syndrome (KS) is a genetic disorder caused by pathogenic variants in KMT2D or KDM6A, and manifesting with multi-systemic involvement, including recognizable facial features, developmental delay and multiple congenital anomalies. Ophthalmological involvement has been described in varying rates in several studies. We aimed to evaluate the prevalence and nature of ophthalmological findings in a cohort of KS patients in Israel. Read More

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