Sex Transm Dis 2021 Jul 24. Epub 2021 Jul 24.
Assistant Professor, Division of Infectious Diseases and Global Health, Department of Medicine, University of California, San Diego Assistant Professor, Fielding School of Public Health, University of California, Los Angeles, USA Associate Professor, Division of Infectious Diseases and Global Health, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA USA Senior Research Associate, Botswana Harvard Aids Institute Partnership Sexual & Reproductive Health Lead Physician, Botswana UPenn Partnership Professor (Hon), Women's Health Research Unit, Division of Social/Behavioural Sciences, School of Public Health, UCT Clinical Reader in International Sexual and Reproductive Health, Liverpool School of Tropical Medicine Deputy Director, UK Faculty of Sexual and Reproductive Health Care Clinical Effectiveness Unit Deputy Dean of Research and Graduate Studies, Faculty of Medicine, University of Botswana, Acting Dean, School of Medicine, University of Botswana Professor, Fielding School of Public Health, University of California, Los Angeles, USA Professor Emeritus, Luskin School of Public Policy, University of California, Los Angeles, USA.
Introduction: Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are common sexually transmitted infections (STIs) associated with adverse outcomes - yet most countries do not test and conduct syndromic management, which lacks sensitivity and specificity. Innovations allow for expanded STI testing; however, cost is a barrier.
Methods: Using inputs from a pilot program in Botswana, we developed a model among a hypothetical population of 50,000 pregnant women to compare one-year costs and outcomes associated with three antenatal STI testing strategies: 1) point-of-care, 2) centralized laboratory hubs, and 3) a mixed approach (point-of-care at high-volume sites, and hubs elsewhere); and syndromic management. Read More