44,932 results match your criteria scan revealed


Case Report: Metagenomic Next-Generation Sequencing in Diagnosis of Disseminated Tuberculosis of an Immunocompetent Patient.

Front Med (Lausanne) 2021 12;8:687984. Epub 2021 Jul 12.

Department of General Practice, Ningbo First Hospital, Ningbo, China.

Disseminated tuberculosis (TB) is a rare disease and mainly occurs in immunodeficient patients. It is marked by hematogenous or lymphatic dissemination of , causing tuberculous infection involving any organ system. Here, we report a case of disseminated TB involving lung, liver, spine, mediastinum, and prostate in an immunocompetent man. Read More

View Article and Full-Text PDF

A case of hepatic focal nodular hyperplasia mimicking hepatocellular carcinoma identified on gallium-68-prostate-specific membrane antigen positron emission tomography/computed tomography.

World J Nucl Med 2021 Apr-Jun;20(2):192-194. Epub 2021 Feb 12.

Department of Nuclear Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Prostate-specific membrane antigen (PSMA) is a glycosylated type-II transmembrane protein highly expressed in individual tumor cells. Lesions with PSMA expression in the liver are commonly reported as prostate cancer metastasis or hepatocellular cancer previously. This is the first case reported as hepatic focal nodular hyperplasia, mimicking hepatocellular carcinoma with imaging features. Read More

View Article and Full-Text PDF
February 2021

Debating the embolization of a large aberrant systemic artery for pulmonary sequestration using an Amplatzer duct occluder: a case report and literature review.

Cardiol Young 2021 Jul 29:1-6. Epub 2021 Jul 29.

Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan610041, China.

Here, we report two rare cases of pulmonary sequestration that were fed by large systemic arteries and embolized with a large Amplatzer duct occluder and their 3-year follow-up, and we discuss the efficacy and safety of the embolization of a large aberrant systemic artery to pulmonary sequestration using an Amplatzer duct occluder. A 9-year-old boy complained of chest pain for 1 month, and a 6-year-old boy initially complained of recurrent cough for 3 months. A series of examinations was launched to evaluate any possible malformation or abnormalities in the patients. Read More

View Article and Full-Text PDF

What are the odds? Duodenum adenocarcinoma as a primary metachronic neoplasia.

Rev Esp Enferm Dig 2021 Jul 29. Epub 2021 Jul 29.

Gastroenterology, Hospital General Universitario de Elche.

We present a 81-year-old man with a history of colorectal and bladder cancer surgically removed, who was admitted to our hospital with a urinary infection. A routine renal ultrasound revealed a pelvic cyst and CT-scan confirmed a non-complicated cyst but observed a lesion in the left lung. Read More

View Article and Full-Text PDF

Invasive Fungal Infection in COVID-19-Recovered Patient Detected on 18F-FDG-Labeled Leukocytes PET/CT Scan.

Clin Nucl Med 2021 Jul 26. Epub 2021 Jul 26.

From the Department of Nuclear Medicine, Fortis Memorial Research Institute, Gurgaon, Haryana, India.

Abstract: Occurrence of invasive fungal infections has gained significant attention during recent times in patients with COVID-19. Patients with severe form of COVID-19, such as those treated in the intensive care unit with prolonged steroid use, are particularly vulnerable to secondary bacterial and fungal infections. Disseminated systemic mycosis is a life-threatening condition, especially in immunocompromised patients. Read More

View Article and Full-Text PDF

Vesicoureteral Reflux in Nonfunctioning Renal Allograft Incidentally Detected in a Posttransplant 99mTc-DTPA Scan: Significance of Postvoid Imaging.

Authors:
Mohsen Qutbi

Clin Nucl Med 2021 Jul 26. Epub 2021 Jul 26.

From the Department of Nuclear Medicine, Taleghani Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract: In the present note, a case with rising serum creatinine shortly posttransplantation was referred for 99mTc-DTPA scan. The previous nonfunctioning renal allograft in the left hemipelvis showed no finding during dynamic phase of scan and filling phase of bladder but revealed a high-grade vesicoureteral reflux (VUR) in postvoid image, which can be responsible, partly, for the patient's present and prior symptoms. Read More

View Article and Full-Text PDF

Spin-crossover iron(II) long-chain complex with slow spin equilibrium at low temperatures.

Dalton Trans 2021 Jul 28. Epub 2021 Jul 28.

Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry and Chemical Engineering, Liangxiang Campus, Beijing Institute of Technology, Beijing 102488, People's Republic of China.

A mononuclear complex with long alkyl chains, [FeII(H2Bpz2)2(C9bpy)] (1; H2Bpz2 = dihydrobis(1-pyrazolyl)borate, C9bpy = 4,4'-dinonyl-2,2'-bipyridine), was synthesized. Single-crystal X-ray crystallographic studies revealed that the Δ- and Λ-forms of the complex co-crystallized in the lattice asymmetric unit, while magnetic measurements unveiled that this complex underwent incomplete one-step spin crossover (SCO) with the transition completeness and temperature depending on the measurement velocity because of slow spin equilibrium. Multivariable approaches such as varying scan rate, annealing the sample, light irradiation and pressure have been adopted to effectively overcome the slow spin equilibrium and thus improve the SCO completeness. Read More

View Article and Full-Text PDF

Novel Homozygous Truncating Variant Widens the Spectrum of Early-Onset Multisystemic SYNE1 Ataxia.

Cerebellum 2021 Jul 28. Epub 2021 Jul 28.

Department of Neurology, University of Copenhagen, Rigshospitalet, Inge Lehmanns Vej 8, 2100, Copenhagen, Denmark.

Pathogenic variants in the SYNE1 gene are associated with a phenotypic spectrum spanning from late-onset, slowly progressive, relatively pure ataxia to early-onset, fast progressive multisystemic disease. Since its first description in 2007 as an adult-onset ataxia in French Canadian families, subsequent identification of patients worldwide has widened the clinical spectrum and increased the number of identified pathogenic variants. We report a 20-year-old Faroese female with early-onset progressive gait problems, weakness, dysphagia, slurred speech, orthostatic dizziness, and urge incontinence. Read More

View Article and Full-Text PDF

Steganography-based voice hiding in medical images of COVID-19 patients.

Authors:
Melih Yildirim

Nonlinear Dyn 2021 Jul 22:1-16. Epub 2021 Jul 22.

The Scientific and Technological Research Council of Turkey (TUBITAK), Ankara, Turkey.

A novel image steganography technique in order to hide the ciphered voice data has been suggested in this work. The doctor's voice comments belonging to a coronavirus disease 2019 (COVID-19) patient are hidden in a medical image in order to protect the patient information. The introduced steganography technique is based on chaos theory. Read More

View Article and Full-Text PDF

Secondary pleuropulmonary amoebiasis due to liver abscess rupture: A complication case report in low resource setting.

Int J Surg Case Rep 2021 Jul 21;85:106231. Epub 2021 Jul 21.

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Electronic address:

Background: Pleuropulmonary amoebiasis caused by complications of amoebic liver abscess (ALA) is rare.

Case Presentation: A 23 years old male, presented with shortness of breath, cough with yellowish phlegm, right chest pain, fever, bulging stomach, yellow eyes, and swelling of both legs. Abdominal ultrasound and CT scan thorax and abdomen revealed right fluidopneumothorax and liver abscess. Read More

View Article and Full-Text PDF

Growing teratoma syndrome and gliomatosis peritonei in 15-year-old female patient with immature ovarian teratoma - case report and review of literature.

J Pediatr Adolesc Gynecol 2021 Jul 24. Epub 2021 Jul 24.

Department of Pediatrics, Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland.

Gliomatosis peritonei (GP) is a rare clinical condition characterized by presence of mature glial cells in the peritoneum. Growing teratoma syndrome (GTS) is described as an uncommon phenomenon which could be related to the incidence of non-seminomatous germ cell tumors. We report a case of a patient treated for immature ovarian teratoma, where both GP and GTS have been observed, an association to date scarcely described in literature. Read More

View Article and Full-Text PDF

Comparing left ventricular mechanical dyssynchrony between diabetic and non-diabetic patients with normal gated SPECT MPI.

Int J Cardiovasc Imaging 2021 Jul 27. Epub 2021 Jul 27.

Clinical Research Development Unit of Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The aim of this study was to employ phase analysis to diagnose left ventricular mechanical dyssynchrony (LVMD) in asymptomatic patients with diabetes mellitus type 2 and normal perfusion study which may help prevent diabetic cardiomyopathy. Ninety-three consecutive patients with known type 2 diabetes and 81 age- and gender- matched patients without diabetes who were candidates for SPECT-MPI were considered as the control group. The presence of LVMD as an possible risk factor for cardiomyopathy- was determined using phase analysis for each scan with quantitative gated SPECT (QGS) and corridor4DM (4DM) software. Read More

View Article and Full-Text PDF

Aldosterone-producing adenoma-harbouring KCNJ5 mutations is associated with lower prevalence of metabolic disorders and abdominal obesity.

J Hypertens 2021 Jul 26. Epub 2021 Jul 26.

Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University Industrial Ph.D. Program of Biomedical Science and Engineering, School of Biomedical Science and Engineering, National Yang-Ming University Industrial Ph.D. Program of Biomedical Science and Engineering, School of Biomedical Science and Engineering, National Yang Ming Chiao Tung University Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine Department and Graduate Institute of Forensic Medicine, National Taiwan University College of Medicine Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Objective: Aldosterone overproduction and lipid metabolic disturbances between idiopathic hyperaldosteronism (IHA) and unilateral aldosterone-producing adenoma (APA) have been inconsistently linked in patients with primary aldosteronism. Moreover, KCNJ5 mutations are prevalent among APAs and enhance aldosterone synthesis in adrenal cortex. We aimed to investigate the prevalence of metabolic syndrome (MetS) in each primary aldosteronism subtype and observe the role of KCNJ5 mutations among APAs on the distribution of abdominal adipose tissues quantified using computed tomography (CT), including their changes postadrenalectomy. Read More

View Article and Full-Text PDF

Primary Extra-Osseous Ewing Sarcoma of the Thyroid: A Case Report and Review of the Literature.

Head Neck Pathol 2021 Jul 26. Epub 2021 Jul 26.

Department of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.

Extra-osseous Ewing sarcoma (ES) is a rare and aggressive malignant tumor found in a variety of organs. Primary ES of the thyroid is exceedingly rare and few cases have been documented to date. We describe the case of a 54-year old woman with a history of breast carcinoma in whom a unique hypermetabolic left thyroid nodule was identified during a follow-up PET-CT scan. Read More

View Article and Full-Text PDF

Clinical Reasoning: An Unexpected Response to Therapy in a Patient With HIV and Focal Seizures.

Neurology 2021 Jul 26. Epub 2021 Jul 26.

Department of Internal Medicine, University Teaching Hospital, Lusaka, Zambia

We present the case of a 23-year-old right-handed man who presented to an emergency department in Lusaka, Zambia with new-onset headaches and focal seizures. He was on combination antiretroviral therapy (cART) for HIV and had been started on anti-tuberculous therapy at his local clinic two weeks prior to presentation based on chest x-ray findings. On examination, he had subtle weakness and hyperreflexia in his left upper extremity. Read More

View Article and Full-Text PDF

Cranial Nerve Palsy Secondary to Botulism After Black Tar Heroin Use.

J Am Board Fam Med 2021 Jul-Aug;34(4):808-810

From the University of California, Riverside, Department of Family Medicine, University of California, Riverside (HS); St. Bernardine Medical Center, Sound Critical Care, San Bernardino, CA (HR).

Introduction: Wound botulism (WB) is an uncommon but severe neuromuscular illness caused by the bacterium in an infected wound. There has been a dramatic increase in WB associated with black tar heroin injection in California.

Case Description: A 50-year-old male with heroin abuse presented to the emergency department with a 2-day history of dysphagia and dysarthria. Read More

View Article and Full-Text PDF
December 2020

Incidental Finding of Squamous Cell Carcinoma on a 68Ga-DOTATATE PET Scan.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211035232

University of Rochester Medical Center, Rochester, NY, USA.

Neuroendocrine tumors (NETs) are a relatively rare entity; however, the incidence and prevalence of these tumors are increasing, likely attributed to improved diagnostic accuracy. The diagnosis of suspected NETs is facilitated by clinical symptoms, laboratory test abnormalities such as elevated chromogranin-A, and other diagnostic modalities such as the use of computed tomography scans, magnetic resonance imaging scans, positron emission tomography (PET) scans, and biopsy. The expression of high levels of somatostatin receptors in NETs enables the use of a specialized PET scan using the radiolabeled somatostatin analogues 68Ga-DOTATATE. Read More

View Article and Full-Text PDF

Bioprocess development for biosorption of cobalt ions and Congo red from aquatic mixture using Enteromorpha intestinalis biomass as sustainable biosorbent.

Sci Rep 2021 Jul 22;11(1):14953. Epub 2021 Jul 22.

Department of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El‑Arab City, 21934, Alexandria, Egypt.

Because of the increased amount of cobalt and Congo red dye effluents attributable to the industrial operations, the capacity of Enteromorpha intestinalis biomass as a sustainable source to achieve significant biosorption percent for both pollutants from dual solution was assessed. A fifty batch FCCCD experiments for biosorption of cobalt ions and Congo red dye were performed. The complete removal of Congo red dye was obtained at 36th run using an initial pH value of 10, 1. Read More

View Article and Full-Text PDF

Colorectal cancer with first known case of simultaneous bilateral tibial metastases.

Authors:
Ta Li Hsu Karl Wu

J Int Med Res 2021 Jul;49(7):3000605211027773

Department of Orthopedic Surgery, 46608Far Eastern Memorial Hospital, Far Eastern Memorial Hospital, New Taipei City.

The most common osseous metastatic regions for colorectal cancer are the lumbar and sacral vertebrae and the pelvis. There are few reported cases of isolated solitary tibial metastasis, and simultaneous bilateral solitary tibial metastases in colorectal cancer are even rarer. A 62-year-old female patient was admitted to our inpatient clinic 3 years after receiving initial chemotherapy for a rectosigmoid adenocarcinoma with liver metastasis. Read More

View Article and Full-Text PDF

COVID-19-Related Spontaneous Aortic Arch Thrombus With Delayed Embolization.

Am Surg 2021 Jul 25:31348211034744. Epub 2021 Jul 25.

Division of Vascular Surgery and Endovascular Therapy, Loyola University Health System, Maywood, IL, USA.

Presentation of a 62-year-old man with baseline chronic obstructive pulmonary disease admitted to the hospital with dyspnea and newly diagnosed COVID-19 infection. CT scan of the chest was obtained to rule out pulmonary embolism. This revealed a mural thrombus of the inner curvature of the aortic arch with a floating component. Read More

View Article and Full-Text PDF

A case report showing unusual atrial communication with severe regurgitation of multiple valves and pulmonary aneurysm: double atrial septum with persistent interatrial space.

Eur Heart J Case Rep 2021 Jul 1;5(7):ytaa499. Epub 2021 Jul 1.

Complejo Asistencial de Zamora. Hospital Virgen de la Concha. Servicio de Medicina Interna. Sección de Cardiología, Av. Requejo n 6. Zamora, Spain.

Background: We discuss an unusual association: double atrial septum, pulmonary artery aneurysm, and severe regurgitation of multiple valves.

Case Summary: A 70-year-old man was admitted into the hospital because of progressive dyspnoea. Physical examination showed a blood pressure of 132/70 mmHg, a systolic murmur on the right upper sternal border, another systolic murmur at the apex, and a diastolic murmur at the lower left sternal border. Read More

View Article and Full-Text PDF

Ovarian Steroid Cell Tumor Masquerading as Steroid-Unresponsive Congenital Adrenal Hyperplasia.

AACE Clin Case Rep 2021 Jul-Aug;7(4):261-263. Epub 2021 Feb 17.

Division of Pediatric Endocrinology and Metabolism.

Objective: Ovarian neoplasms in children are rare. The objective of this report is to emphasize the importance of considering those neoplasms in the differential diagnosis of hyperandrogenism even with negative diagnostic imaging.

Methods: We report the case of a 12-year-old girl who presented with virilization and elevated 17 hydroxyprogesterone (17-OHP) and who was subsequently diagnosed with an ovarian neoplasm. Read More

View Article and Full-Text PDF
February 2021

Metastatic Malignant Struma Ovarii and Graves' Disease: A Rare Occurrence.

AACE Clin Case Rep 2021 Jul-Aug;7(4):243-246. Epub 2021 Jan 6.

Tan Tock Seng Hospital, Department of Endocrinology, Novena, Singapore.

Objective: Malignant struma ovarii (SO) is a rare condition. Although there have been a few reported cases of malignant SO with coexisting Graves' disease (GD), the exact incidence of metastasis in these cases is not known. We report a rare case of metastatic malignant SO coexisting with GD. Read More

View Article and Full-Text PDF
January 2021

Splenosis masquerading as gastric stromal tumor: A case report.

World J Clin Cases 2021 Jul;9(20):5724-5729

Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China.

Background: Splenosis is a rare benign disease that often disguises itself as a malignant tumor. There are few articles providing a comprehensive description of splenosis, especially cases located in the stomach being treated by laparoscopic surgery.

Case Summary: A 44-year-old man presented with recurrent upper abdominal pain for more than half a year. Read More

View Article and Full-Text PDF

Gelfoam embolization for distal, medium vessel injury during mechanical thrombectomy in acute stroke: A case report.

World J Clin Cases 2021 Jul;9(20):5668-5674

Department of Radiology, Chungbuk National University Hospital, Cheongju 28644, South Korea.

Background: Arterial perforation has inevitably increased as endovascular treatments have become more common for intracranial large vessel occlusions, and even distal, medium vessel occlusions. A distal, medium vessel has a tortuous course and thinner wall compared to large arteries, making it more susceptible to damage. Here, we review the treatment strategies for arterial perforation during mechanical thrombectomy, and we report the case of a patient treated with gelfoam embolization. Read More

View Article and Full-Text PDF

Villous adenoma of the renal pelvis: a common entity at an uncommon location.

Autops Case Rep 2021 6;11:e2021283. Epub 2021 May 6.

All India Institute of Medical Sciences (AIIMS) Jodhpur, Department of Pathology & Lab Medicine, Jodhpur, Rajasthan, India.

Villous adenoma is uncommonly seen in the urogenital tract and is even more rarely seen in the upper urinary tract and renal pelvis. Like colorectal adenomas, these neoplasms can transform into adenocarcinoma. The preoperative diagnosis is challenging due to their frequent association with hydronephrosis. Read More

View Article and Full-Text PDF

Concomitant Langerhans cell histiocytosis of cervical lymph nodes in adult patients with papillary thyroid carcinoma: A report of two cases and review of the literature.

Autops Case Rep 2021 12;11:e2021253. Epub 2021 Mar 12.

King Hussein Cancer Center, Department of Pathology and Laboratory Medicine, Amman, Jordan.

Objective: : Langerhans cell histiocytosis (LCH) is an uncommon entity of unknown etiology. It contains a wide range of clinical presentations. The discovery of oncogenic mutation in LCH has provided additional evidence that LCH is a neoplasm. Read More

View Article and Full-Text PDF

Liver Granulocytic Sarcoma With Megakaryocytic Differentiation: A Rare Extra Medullary Involvement That Warrants Liver Biopsy for Prompt Diagnosis.

Cureus 2021 Jul 13;13(7):e16366. Epub 2021 Jul 13.

Department of Internal Medicine, State University of New York (SUNY) Downstate Health Sciences University, Brooklyn, USA.

Granulocytic sarcoma (GS) is an extramedullary manifestation of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) or myeloproliferative neoplasms. The diagnosis depends on morphology, immunohistochemistry and flow cytometry. An unusual location of this tumor may mask its primary source, therefore, a strategy involving immediate symptom control, and investigation is crucial in preventing clinical deterioration. Read More

View Article and Full-Text PDF

Incidental Finding of Right-Sided Idiopathic Spontaneous Acquired Diaphragmatic Hernia.

Cureus 2021 Jun 21;13(6):e15793. Epub 2021 Jun 21.

Medicine, Bangalore Medical College & Research Institute, Bengaluru, IND.

Spontaneous acquired diaphragmatic hernia is a rare finding which occurs in the absence of any trauma or surgery. Here, we present the case of an 83-year-old male who presented to the outpatient department complaining of nausea, vomiting, epigastric pain and sensation of fullness, loss of appetite, and occasional episodes of constipation, with no history of trauma or surgery. Clinical examination revealed no specific cause. Read More

View Article and Full-Text PDF

Case Report: A Challenging Localization of a Pulmonary Ectopic ACTH-Secreting Tumor in a Patient With Severe Cushing's Syndrome.

Front Endocrinol (Lausanne) 2021 9;12:687539. Epub 2021 Jul 9.

Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.

Background: Ectopic adrenocorticotropic syndrome (EAS) is a rare cause of endogenous ACTH-dependent Cushing's syndrome, usually associated with severe hypercortisolism as well as comorbidities. Tumor detection is still a challenge and often requires several imaging procedures. In this report, we describe a case of an ectopic ACTH secretion with a misleading localization of the responsible tumor due to a concomitant rectal carcinoma. Read More

View Article and Full-Text PDF