100,818 results match your criteria saudi arabia


Risk factors associated with the development of diabetic kidney disease in Sudanese patients with type 2 diabetes mellitus: A case-control study.

Diabetes Metab Syndr 2021 Oct 20;15(6):102320. Epub 2021 Oct 20.

Dr. Salma Center for Kidney Diseases, University of Khartoum, Khartoum, Sudan.

Background And Aims: Limited data are available regarding the risk factors associated with the development of diabetic kidney disease (DKD) among Sudanese adults with type 2 diabetes mellitus (T2DM).

Methods: A case-control study was conducted at Dr. Salma Center for Kidney Diseases between April and September 2019. Read More

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October 2021

Opportunistic mycoses in COVID-19 patients/survivors: Epidemic inside a pandemic.

J Infect Public Health 2021 Oct 15;14(11):1720-1726. Epub 2021 Oct 15.

Department of Obstetrics and Gynecology, Centre for Perinatal and Reproductive Medicine, University of Perugia, Perugia, Italy. Electronic address:

Being considered minor vexations, fungal infections hinder the life of about 15% of the world population superficially, with rare threats to life in case of invasive sepsis. A significant rise in the intrusive mycoses due to machiavellian fungal species is observed over the years due to increased pathology and fatality in people battling life-threatening diseases. Individuals undergoing therapy with immune suppressive drugs plus recovering from viral infections have shown to develop fungal sepsis as secondary infections while recovering or after. Read More

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October 2021

Candida utilis and Stenotrophomonas maltophilia causing nosocomial meningitis following a neurosurgical procedure: A rare co-infection.

J Infect Public Health 2021 Oct 13;14(11):1715-1719. Epub 2021 Oct 13.

Department of Infectious Diseases, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; Department of Infectious Diseases, Al-Moosa Specialist Hospital, Al-Ahsa, Saudi Arabia.

Candida utilis and Stenotrophomonas maltophilia co-infections connected to meningitis are uncommon. We describe a patient who developed C. utilis and S. Read More

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October 2021

A pre-experimental pilot study exploring EBP Beliefs and EBP Implementation among post-graduate student nurses in Saudi Arabia.

Nurse Educ Pract 2021 Sep 30;57:103215. Epub 2021 Sep 30.

Dublin City University, School of Nursing, Psychotherapy and Community Health, Dublin D09Y5NO, Ireland. Electronic address:

Aim: This study aimed to measure the impact of a dedicated EBP module on the knowledge, skills and capability for EBP of students undertaking the inaugural MSc in Nursing: Advanced Practice programme in the KSA.

Background: Evidence-based practice (EBP) yields multiple benefits for all key stakeholders of healthcare. Key to this are healthcare professionals armed with necessary EBP knowledge and skills. Read More

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September 2021

Efficacy of Antimicrobial photodynamic therapy (aPDT) in reducing cariogenic bacteria in primary deciduous dentine.

Authors:
Hiba F Kattan

Photodiagnosis Photodyn Ther 2021 Oct 23:102600. Epub 2021 Oct 23.

Preventive Dental Science Department, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia. Electronic address:

Aim: The aim is to systematically review the efficacy of aPDT in minimizing cariogenic bacteria in primary dentine when compared to tooth preparation and endodontic debridement.

Materials And Methods: The focused question was: Is aPDT (intervention) effective in minimizing the cariogenic bacteria (outcome) in deciduous dentine (participants) after caries removal when compared to before aPDT or mechanical caries removal alone (controls). The keywords that were used were: 'antimicrobial photodynamic therapy', 'dentine', 'primary teeth' and 'deciduous teeth' in different combinations. Read More

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October 2021

Effectiveness of synthetic and natural Photosensitizers and different chemical disinfectants on the contaminated metal crown.

Photodiagnosis Photodyn Ther 2021 Oct 23:102601. Epub 2021 Oct 23.

Department of Prosthetic Dental Science, College of Dentistry, King Saud University; Research Chair for Biological Research in Dental Health, College of Dentistry, Riyadh 11545, Saudi Arabia. Electronic address:

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October 2021

Interactive effects of dietary quercetin nanoparticles on growth, flesh antioxidant capacity and transcription of cytokines and Aeromonas hydrophila quorum sensing orchestrating genes in Nile tilapia (Oreochromis niloticus).

Fish Shellfish Immunol 2021 Oct 23. Epub 2021 Oct 23.

Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44511, Egypt.

Recently, the concept of incorporating natural products into nanocarriers has been intended to promote fish growth and health via modulating their stability and bioavailability. In this concern, the potential role of reformulated quercetin into nanocarriers was examined, for the first time, on Nile tilapia's performance and immunity, flesh quality and antioxidant indices and disease resistance. Five hundred fish assigned into five experimental groups with formulated diets containing quercetin nanoparticles (QT-NPs) at levels of 0, 100, 200, 300 and 400 mg/kg were challenged with Aeromonas hydrophila (A. Read More

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October 2021

Vector-borne and zoonotic infections and their relationships with regional and socioeconomic statuses: A survey in 24 countries of Europe, Africa and Asia.

Travel Med Infect Dis 2021 Oct 23:102174. Epub 2021 Oct 23.

Department of Infectious and Tropical Diseases, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.

Background: In this cross-sectional, international study, we aimed to analyze vector-borne and zoonotic infections (VBZI), which are significant global threats.

Method: VBZIs' data between May 20-28, 2018 was collected. The 24 Participatingcountries were classified as lower-middle, upper-middle, and high-income. Read More

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October 2021

Reef accumulation is decoupled from recent degradation in the central and southern Red Sea.

Sci Total Environ 2021 Oct 23:151176. Epub 2021 Oct 23.

School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia; Australian Research Council Centre of Excellence for Coral Reef Studies, The University of Queensland, Brisbane, QLD 4072, Australia.

Reefs are biogenic structures that result in three-dimensional accumulations of calcium carbonate. Over geological timescales, a positive balance between the production and accumulation of calcium carbonate versus erosional and off-reef transport processes maintains positive net accretion on reefs. Yet, how ecological processes occurring over decadal timescales translate to the accumulation of geological structures is poorly understood, in part due to a lack of studies with detailed time-constrained chronologies of reef accretion over decades to centuries. Read More

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October 2021

An evaluation study of biclusters visualization techniques of gene expression data.

J Integr Bioinform 2021 Oct 26. Epub 2021 Oct 26.

Departamento de Informática y Automática, Universidad de Salamanca, Salamanca, Spain.

is a non-supervised data mining technique used to analyze gene expression data, it consists to classify subgroups of genes that have similar behavior under subgroups of conditions. The classified genes can have independent behavior under other subgroups of conditions. Discovering such co-expressed genes, called , can be helpful to find specific biological features such as gene interactions under different circumstances. Read More

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October 2021

The value of blue-green algae (Spirulina platensis) as a nutritive supplement and toxicant against almond moth [Cadra cautella (Lepidoptera: Pyralidae)].

PLoS One 2021 26;16(10):e0259115. Epub 2021 Oct 26.

Department of Food Sciences and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.

Blue-green algae, Spirulina platensis is a well-known algal formulation known for its beneficial effects on the growth and development in several types of organisms. Although it is used as a food supplement, it possesses significant toxic effects on growth and development of organisms. This study assessed the positive/negative impacts of S. Read More

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October 2021

Early administration of remdesivir to COVID-19 patients associates with higher recovery rate and lower need for ICU admission: A retrospective cohort study.

PLoS One 2021 26;16(10):e0258643. Epub 2021 Oct 26.

Sharjah Institute of Medical Research, University of Sharjah, Sharjah, United Arab Emirates.

Objectives: Remdesivir is one of the most widely recommended and used medications for COVID-19 treatment. However, different outcomes have been reported for hospitalized patients with COVID-19 treated with remdesivir. Specifically, the effect of the timing of remdesivir initiation (from patient's symptom onset) on clinical outcomes in COVID-19 patients has not been investigated. Read More

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October 2021

In Situ Fabrication of Nickel-Iron Oxalate Catalysts for Electrochemical Water Oxidation at High Current Densities.

ACS Appl Mater Interfaces 2021 Oct 26. Epub 2021 Oct 26.

Optoelectronic Convergence Research Center, Department of Materials Science and Engineering, Chonnam National University, Gwangju 500-757, South Korea.

Ni-Fe-based electrode materials are promising candidates for the oxygen evolution reaction (OER). The synergy between Fe and Ni atoms is crucial in modulating the electronic structure of the active site to enhance electrochemical performance. Herein, a simple chemical immersion technique was used to grow Ni-Fe oxalate nanowires directly on a porous nickel foam substrate. Read More

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October 2021

Can manipulation of gut microbiota really be transformed into an intervention strategy for cardiovascular disease management?

Folia Microbiol (Praha) 2021 Oct 26. Epub 2021 Oct 26.

King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Recent advancement in manipulation techniques of gut microbiota either ex vivo or in situ has broadened its plausible applicability for treating various diseases including cardiovascular disease. Several reports suggested that altering gut microbiota composition is an effective way to deal with issues associated with managing cardiovascular diseases. However, actual translation of gut microbiota manipulation-based techniques into cardiovascular-therapeutic approach is still questionable. Read More

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October 2021

Non-invasive neuromodulation in the acute treatment of migraine: a systematic review and meta-analysis of randomized controlled trials.

Neurol Sci 2021 Oct 26. Epub 2021 Oct 26.

Division of Pediatric Neurology, Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G1X8, Canada.

Objective: A systematic review and meta-analysis was performed to determine the efficacy of non-invasive neuromodulation modalities for the treatment of acute migraine.

Background: Although pharmacological treatments are the gold standard for the management of acute migraine, some patients may require non-pharmacological treatment options. Non-invasive neuromodulation may provide an alternative, and techniques include transcranial magnetic stimulation (TMS), non-invasive vagal nerve stimulation (nVNS), non-painful remote electrical stimulation (NRES), and external trigeminal nerve stimulation (e-TNS). Read More

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October 2021

Pharmacy Students' Perceptions and Attitudes towards Online Education during COVID-19 Lockdown in Saudi Arabia.

Pharmacy (Basel) 2021 Oct 14;9(4). Epub 2021 Oct 14.

School of Life and Medical Sciences, University of Hertfordshire (Hosted by Global Academic Foundation), 6 (R5), Cairo 11835, Egypt.

In March 2020, a national lockdown in Saudi Arabia due to the pandemic forced all educational institutions to complete their academic year via online education. This study aims to explore pharmacy students' perceptions and assess their attitude towards online education during the lockdown. A cross-sectional self-administered survey was designed to collect responses of pharmacy students (from one college of pharmacy in Saudi Arabia) from December 2020 through January 2021. Read More

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October 2021

Dietary Habits and Musculoskeletal Pain in Statin and Red Yeast Rice Users: A Pilot Study.

Eur J Investig Health Psychol Educ 2021 Sep 29;11(4):1156-1165. Epub 2021 Sep 29.

Research Centre for Food and Nutrition, Council for Agricultural Research and Economics (CREA-AN), 00142 Rome, Italy.

(1) Background: Diet and statins are commonly used to treat high cholesterol (CHOL) levels. (2) Aim: To compare adherence to Mediterranean diet (Med-D), orthorexia nervosa (ON), and musculoskeletal pain in individuals in treatment with statins metabolized by CYP3A4, not metabolized by CYP3A4 or red yeast rice (RYR, containing monacolin K: MON-K). (3) Methods: starting from 80 individuals, after the exclusion of those with other causes of possible pain, 56 individuals were selected and divided into three groups according to the type of statin (CYP3A4, NO-CYP3A4 and MON-K). Read More

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September 2021

Vitamin D Receptor Gene Variants Susceptible to Osteoporosis in Arab Post-Menopausal Women.

Curr Issues Mol Biol 2021 Sep 27;43(3):1325-1334. Epub 2021 Sep 27.

Chair for Biomarkers of Chronic Diseases, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Post-menopausal osteoporosis (PMO) is a multifactorial bone disorder in elderly women. Various vitamin D receptor (VDR) gene variants have been studied and associated with osteoporosis in other populations, but not in a homogenous Arab ethnic group. Herein, the current study explores the association between VDR polymorphisms and susceptibility to osteoporosis in Saudi postmenopausal women. Read More

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September 2021

Effect of and Extracts on Inhibition of Human Colon and Prostate Cancer Cell Lines.

Curr Issues Mol Biol 2021 Oct 10;43(3):1518-1528. Epub 2021 Oct 10.

College of Biotechnology, Misr University for Science and Technology, Giza 12563, Egypt.

The goal of this study was to investigate whether and methanol extract the have effect on colon and prostate cancer cell lines. Analysis of total content of phenolics and flavonoids of each plant extract was carried out. Cytotoxic effect, cell cycle analysis, induction of apoptosis and gene expression of and genes were studied. Read More

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October 2021

Genistein: A Potent Anti-Breast Cancer Agent.

Curr Issues Mol Biol 2021 Oct 10;43(3):1502-1517. Epub 2021 Oct 10.

Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.

Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations into mechanisms of the anti-cancer activity have revealed many pathways including induction of cell proliferation, suppression of tyrosine kinases, regulation of Hedgehog-Gli1 signaling, modulation of epigenetic activities, seizing of cell cycle and Akt and MEK signaling pathways, among others via which the cancer cell proliferation can be controlled. Read More

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October 2021

Hybrid Antibody-Aptamer Assay for Detection of Tetrodotoxin in Pufferfish.

Anal Chem 2021 Oct 26. Epub 2021 Oct 26.

Interfibio, Nanobiotechnology and Bioanalysis Group, Departament d'Enginyeria Química, Universitat Rovira i Virgili, Avinguda Paisos Catalans 26, 43007 Tarragona, Spain.

The marine toxin tetrodotoxin (TTX) poses a great risk to public health safety due to its severe paralytic effects after ingestion. Seafood poisoning caused by the consumption of contaminated marine species like pufferfish due to its expansion to nonendemic areas has increased the need for fast and reliable detection of the toxin to effectively implement prevention strategies. Liquid chromatography-mass spectrometry is considered the most accurate method, although competitive immunoassays have also been reported. Read More

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October 2021

Investigating patient outcomes and healthcare costs associated with ventilator-associated pneumonia.

Nurs Manag (Harrow) 2021 Oct 26. Epub 2021 Oct 26.

School of Nursing, clinical nursing, The University of Jordan, Amman, Jordan.

Background: Ventilator-associated pneumonia is the most frequent infection seen in intensive care units. Of those patients with an endotracheal tube, many will develop ventilator-associated pneumonia within 48 hours of being mechanically ventilated. There are many issues related to mechanical ventilation including costs, patient outcomes and the amount of suffering patients experience during the process. Read More

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October 2021

Towards revealing the global diversity and community assembly of soil eukaryotes.

Ecol Lett 2021 Oct 25. Epub 2021 Oct 25.

Institute of Ecology and Earth Sciences, University of Tartu, Tartu, Estonia.

Soil fungi, protists, and animals (i.e., the eukaryome) play a critical role in key ecosystem functions in terrestrial ecosystems. Read More

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October 2021

A recurrent rare intronic variant in CAPN3 alters mRNA splicing and causes autosomal recessive limb-girdle muscular dystrophy-1 in three Pakistani pedigrees.

Am J Med Genet A 2021 Oct 25. Epub 2021 Oct 25.

Center for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina, USA.

Autosomal recessive limb-girdle muscular dystrophy-1 (LGMDR1) is an autosomal recessive disorder characterized by progressive weakness of the proximal limb and girdle muscles. Biallelic mutations in CAPN3 are reported frequently to cause LGMDR1. Here, we describe 11 individuals from three unrelated consanguineous families that present with typical features of LGMDR1 that include proximal muscle wasting, weakness of the upper and lower limbs, and elevated serum creatine kinase. Read More

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October 2021

Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia.

Br J Haematol 2021 Oct 25. Epub 2021 Oct 25.

Campus of Haematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo, Italy.

In β-thalassaemia, the severity of inherited β-globin gene mutations determines the severity of the clinical phenotype at presentation and subsequent transfusion requirements. However, data on associated long-term outcomes remain limited. We analysed data from 2109 β-thalassaemia patients with available genotypes in a global database. Read More

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October 2021

Monitoring of linear alkyl benzenes (LABs) in riverine and estuarine sediments in Malaysia.

Environ Geochem Health 2021 Oct 25. Epub 2021 Oct 25.

Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, 81411, Saudi Arabia.

The aim of this a pioneering research is to investigate linear alkylbenzenes (LABs) as biomarkers of sewage pollution in sediments collected from four rivers and estuaries of the south and east of Peninsular Malaysia. The sediment samples went through soxhlet extraction, two-step column chromatography purification, fractionation and gas chromatography-mass spectrometry (GC-MS) analysis. Principal component analysis (PCA) with multivariate linear regression (MLR) was used as well for source apportionment of LABs. Read More

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October 2021

Association between maternal serum 25-hydroxyvitamin D concentrations and the risk of pre-eclampsia in central Sudan: a case-control study.

Trans R Soc Trop Med Hyg 2021 Oct 25. Epub 2021 Oct 25.

Department of Obstetrics and Gynecology, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Kingdom of Saudi Arabia.

Background: There are few published data on the role of vitamin D concentrations during pregnancy in sub-Saharan Africa. Thus, the aim of the current study was to investigate the association between 25-hydroxyvitamin D (25[OH)]D) levels and pre-eclampsia.

Method: A case-control study, with 60 women in each arm, was conducted in Medani Hospital in Sudan. Read More

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October 2021

The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-, IL 1, and NF- Expressions in Acute Pancreatitis in Albino Rats.

J Diabetes Res 2021 16;2021:6229460. Epub 2021 Oct 16.

Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, and Department of Basic Medical Science, Faculty of Medicine, King Salman International University, Cairo, Egypt.

Severe acute pancreatitis (SAP) is a necrotic pancreatic inflammation associated with high mortality rate (up to 70%). Bone marrow (BM) mesenchymal stem cells (MSCs) have been investigated in pancreatic cellular regeneration, but still their effects are controversial. Therefore, the present study is aimed at examining the enrichment of the stem cells with ascorbic acid (AA) and N-acetylcysteine (NAC) and explore their combined action on the expression of the inflammatory cytokines: interleukin 1 (IL 1), tumor necrosis factor- (TNF-), and nuclear factor- (NF-). Read More

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October 2021

The Dynamic Movement of Disaster Management Systems Based on Vehicle Networks and Applied on the Healthcare System.

Appl Bionics Biomech 2021 16;2021:5710294. Epub 2021 Oct 16.

Department of Computer Engineering, College of Computers and Information Technology, Taif University, Taif, Saudi Arabia.

In order to save human life and assets, the emergency management system (DMS) requires roving rescue teams to respond promptly and effectively. Installation and restoration of appropriate communication infrastructure are important for reducing the effect of disasters and enabling and coordinating information flow among relief teams working in the region. This paper describes a data collection system based on vehicular cloud network services that incorporates the advantages of both architectures of vehicular ad hoc networks (VANETs) with the cloud to establish vehicular cloud networks (VCNs). Read More

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October 2021

Green synthesis of zinc oxide nanoparticles using Elaeagnus angustifolia L. leaf extracts and their multiple in vitro biological applications.

Sci Rep 2021 Oct 25;11(1):20988. Epub 2021 Oct 25.

Botany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.

Due to their versatile applications, ZnONPs have been formulated by several approaches, including green chemistry methods. In the current study, convenient and economically viable ZnONPs were produced using Elaeagnus angustifolia (EA) leaf extracts. The phytochemicals from E. Read More

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October 2021