42 results match your criteria satureja khuzestanica


Mediated Synthesis of Silver Nanoparticles and Its Evaluation of Antineoplastic Activity to Combat Colorectal Cancer Cell Line.

Iran J Pharm Res 2020 ;19(4):169-180

Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Several formulations of herbal plants have been extensively applied to treat diseases. ( is an Iranian traditional plant with a wide range of benefit effects on different diseases. In this study, we aimed to prepare silver nanoparticles from via the green synthesis method and investigate the anti-cancer effects on the HT29 cell line. Read More

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January 2020

Comparison of the effectiveness of and clotrimazole vaginal creams for the treatment of vulvovaginal candidiasis.

J Med Life 2021 Jan-Mar;14(1):111-117

Department of Biostatistics and Epidemiology, Faculty of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Candidal vaginitis has a relatively high prevalence, and its resistance to treatment is on the rise. Considering the complications of chemical drugs, the use of herbal medicines has now been favored due to the lack of changes in the normal vaginal flora. The aim of this study was to compare the effectiveness of and clotrimazole vaginal creams for the treatment of candidal vulvovaginitis. Read More

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Carvacrol loaded beta cyclodextrin-alginate-chitosan based nanoflowers attenuates renal toxicity induced by malathion and parathion: A comparative toxicity.

Pestic Biochem Physiol 2021 Feb 9;172:104747. Epub 2020 Nov 9.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, Iran; Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address:

Most of approximately 1.8 billion people involved in agriculture protect their food products using pesticides especially insecticides which may remain in foods as pesticide residues. Among insecticides organophosphates such as malathion have been widely used around the world and others such as parathion has been restricted because of their toxicity. Read More

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February 2021

Antimicrobial activity of Jamzad and Bunge essential oils against and in table cream containing LU5.

Food Sci Nutr 2020 Nov 17;8(11):5907-5915. Epub 2020 Sep 17.

Department of Food Science and Technology Tarbiat Modares University Tehran Iran.

The essential oils (EOs) from Marzeh khuzestani ( Jamzad) and Marzeh bakhtiari ( Bunge) were analyzed and their antibacterial activities on and in probiotic table cream containing LU5 were evaluated. Carvacrol (86.5%) was the main component of Marzeh khuzestani, but thymol (33. Read More

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November 2020

Antimicrobial Activities of Satureja khuzestanica Jamzad; A Review.

Infect Disord Drug Targets 2020 Jun 10. Epub 2020 Jun 10.

Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad. Iran.

Satureja khuzestanica Jamzad. is a species native to Iran, highly important in Southwestern regions. It belongs to the Lamiaceae family and grows in different climates. Read More

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Control of nectarine fruits postharvest fungal rots caused by and via some essential oils.

J Food Sci Technol 2020 May 9;57(5):1647-1655. Epub 2019 Dec 9.

4Department of Horticultural Science, University of Mohaghegh Ardabili, Ardabil, Iran.

Nectarines ( L. Bath) are very sensitive fruit to fungal infection. Today, the control of postharvest fruit diseases with essential oils (EOs) has been significantly noticed as a novel trend in biological preservation. Read More

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A Systematic Review of the Effects of Jamzad and Boiss against .

Iran J Med Sci 2020 Mar;45(2):83-90

Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.

Background: The use of antibiotics is common, but its excessive or improper use leads to antibiotic resistance. Consequently, scientists have been interested in exploring traditional medicine to identify a new source of anti-bacterial agents. The present study aimed to conduct a systematic review to determine the anti-bacterial activity of Jamzad (SKJ) and Boiss (ZM) essential oils against in vitro. Read More

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Essential Oil against Quorum Sensing of Using RT-PCR.

Iran J Public Health 2019 Jul;48(7):1390-1391

Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.

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Isolation and functional characterization of an antifungal hydrophilic peptide, Skh-AMP1, derived from Satureja khuzistanica leaves.

Phytochemistry 2019 Aug 23;164:136-143. Epub 2019 May 23.

Department of Mycology, Pasteur Institute of Iran, Tehran, 1316943551, Iran. Electronic address:

The increasing resistance of pathogenic fungi to conventional antifungal therapies is a major global health concern. Currently, antifungal peptides are receiving increasing attention as suitable candidates for antifungal drug discovery. In the present study, an antifungal peptide was isolated from Satureja khuzistanica by reverse phase-HPLC column and sequenced by de novo sequencing and Edman degradation. Read More

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Development and characterization of biocomposite films made from kefiran, carboxymethyl cellulose and Satureja Khuzestanica essential oil.

Food Chem 2019 Aug 18;289:443-452. Epub 2019 Mar 18.

Department of Food Science and Technology, University of Tabriz, Tabriz 51666-16471, Iran. Electronic address:

Kefiran-carboxymethyl cellulose biocomposite films incorporated with Satureja Khuzestanica essential oil were developed and characterized. Results indicated that increase in the concentration of the essential oil increased ultimate tensile strength and contact angle but decreased elongation at break, moisture content and water vapor permeability. It also significantly altered color parameters and the percentage of light transmission in the visible and ultraviolet range. Read More

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Antifungal and antibacterial activities of polyherbal toothpaste against oral pathogens, in .

Curr Med Mycol 2018 Jun;4(2):21-26

Student Research Committee, Abadan School of Medical Sciences, Abadan, Iran.

Background And Purpose: Herbal toothpastes are more secure and efficacious and less poisonous due to containing natural chemicals as compared with the synthetic toothpastes. The present study aimed to formulate a polyherbal toothpaste using accessible medicinal plants in Iran and evaluate its efficiency in the protection of oral hygiene and prevention of dental caries.

Materials And Methods: The developed toothpaste was made of the leaf extracts of , (Jamzad), and (Linn), combined at four different dilutions, namely 1:4 (25%), 1:1 (50%), 3:4 (75%), and (100%), with sterile distilled water. Read More

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In Vitro Anti-mycobacterial Activity of Three Medicinal Plants of Lamiaceae Family.

Recent Pat Antiinfect Drug Discov 2018 ;13(3):240-245

Department of Medical Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Mycobacterium tuberculosis as an intracellular pathogen causes Tuberculosis (TB). Due to the long time required for treatment, hepatotoxicity of drugs and also emergence of Multidrug-Resistant (MDR) and Extremely Drug Resistant (XDR) strains, TB is currently a major public health problem. Some medicinal plants possess remarkable activity against Mycobacterium. Read More

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Anti-Proliferative and Pro-Apoptotic Properties of on Human Breast Cancer Cell Line (MCF-7) and Its Synergic Effects with Anticancer Drug Vincristine.

Iran J Pharm Res 2018 ;17(1):343-352

Research Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.

Jamzad (Marzeh Khuzestani in Persian) is an endemic plant that is widely distributed in the southern part of Iran. Despite the number of papers published on this plant, no one has focused on its anticancer effects. Therefore, the present study was designed to investigate the selective cytotoxic and anti-proliferative properties of total extract (SKE). Read More

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January 2018

Busulfan-mediated oxidative stress and genotoxicity decrease in sperm of Satureja Khuzestanica essential oil-administered mice.

Syst Biol Reprod Med 2018 Oct 20;64(5):348-357. Epub 2018 Mar 20.

c Department of Biology, Faculty of Sciences , University of Guilan , Rasht , Iran.

Here, we studied the protective effects of Satureja Khuzestanica essential oil (SKEO) as a potent anti-oxidant, against damage caused by chemotherapy with busulfan in testis and epididymal sperm of adult mice. The NMRI adult mice were assigned: G1: control, G2: was treated with busulfan (4 days, 3.2 mg/kg), G3: was treated with busulfan (4 days, 3. Read More

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October 2018

Effect of Satureja essential oil against fertility disorders induced by busulfan in female mice.

Vet Res Forum 2017 15;8(4):281-286. Epub 2017 Dec 15.

Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

Busulfan is an alkylating agent affects ovarian follicles growth by oxidative stress induction. has antioxidant effects. The aim of this study was to examine whether essential oil (SKEO) exhibits protective effects on busulfan-induced ovarian failure. Read More

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December 2017

Isolation and antifungal activity evaluation of Satureja khuzestanica Jamzad extract against some clinically important dermatophytes.

J Mycol Med 2017 Dec 8;27(4):554-560. Epub 2017 Sep 8.

The Agricultural and Natural of Resources center, Ahvaz, Iran.

Objective: Among the fungi, dermatophytes are the major cause of spectrum of superficial mycoses medically known as dermatophytosis (tinea) in human and animal. Treatment of these infections has still remained difficult. The aim of this survey was to evaluate in vitro anti-dermatophytic activity of ethanolic extract (EtOH) from Satureja khuzestanica leaf (SKLE) against some clinically important dermatophyte species from the genera of Trichophyton, Microsporum and Epidermophyton. Read More

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December 2017

Pseudomoniasis phytotherapy: a review on most important Iranian medicinal plants effective on .

Iran J Microbiol 2016 Oct;8(5):347-350

Razi Herbal Medicines Research Center and Department of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.

Background And Objectives: is a Gram-negative, aerobic bacterium found in water and soil. It is a normal flora in skin and gastrointestinal tract of human beings. as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibiotics. Read More

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October 2016

Effect of olive leaf, , and extracts on cysts compared with metronidazole in vitro.

J Parasit Dis 2016 Dec 14;40(4):1204-1209. Epub 2015 Feb 14.

Young Researcher Club, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran.

is one of the common causes of worldwide diarrhea in children. Appropriate medicinal treatment for giardiasis is available but there are some evidences of drug resistance, insufficient efficacy, and unpleasant side effects. In order to reach a more natural drug with suitable efficacy and the lowest side effects, the effects of the hydroalcoholic extracts of olive leaf, , and on cysts were evaluated in vitro, as well as antigiardial effect of the extracts was compared with metronidazole as the drug of choice. Read More

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December 2016

A Critical Overview on the Pharmacological and Clinical Aspects of Popular Satureja Species.

J Acupunct Meridian Stud 2016 Jun 30;9(3):118-27. Epub 2016 Apr 30.

Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Throughout the world, various parts of most Satureja species are traditionally used to treat patients with various diseases and complications. As for the presence of different classes of metabolites in Satureja and their numerous ethnomedical and ethnopharmacological applications, many species have been pharmacologically evaluated. The current work aimed to compile information from pharmacological studies on this savory for further investigations. Read More

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Protection against Cyclosporine-Induced Reprotoxicity by Satureja khuzestanica Essential Oil in Male Rats.

Int J Fertil Steril 2016 Jan-Mar;9(4):548-57. Epub 2015 Dec 23.

Department of Biology, Faculty of Science, Urmia University, Urmia, Iran.

Background: The effects of cyclosporine (Cs), a fungal cyclic polypeptide with potent immunosuppressive activity, on fertility have assumed greater significance with the increasing numbers of transplantations being performed all over the world. Current study was undertaken to investigate the potential of Satureja khuzestanica Essential Oil (SEO) as an antioxidant to mitigate Cs-induced reprotoxicity.

Materials And Methods: In this experimental study (April-July 2012), thirty-two adult male Wistar rats were randomly divided into 4 groups of 8 animals each. Read More

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Effects of essential oil of Satureja khuzestanica on the oxidative stress in experimental hyperthyroid male rat.

Vet Res Forum 2015 15;6(3):233-8. Epub 2015 Sep 15.

Reproductive Biology Department, School of Advanced Medical Sciences and Technologies, Shiraz, Iran; ; Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

This work analyzes the effects of Satureja khuzestanica essential oil (SKEO) on the thyroid and antioxidant system, assessed by measuring levels of tri-iodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), malondialdehyde (MDA), reduced glutathione (GSH), and glutathione peroxidase (GPx) activity. Forty adult male Sprague Dawley rats (225 ± 25 g) were divided into five equal groups: one control and four hyperthyroid groups that received placebo, 200 mg kg(-1) body weight of vitamin (Vit.) E, 225 mg kg(-1) body weight of SKEO, 200 and 225 mg kg(-1) body weight of Vit. Read More

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February 2016

Cytoprotective and anti-apoptotic effects of Satureja khuzestanica essential oil against busulfan-mediated sperm damage and seminiferous tubules destruction in adult male mice.

Andrologia 2016 Feb 25;48(1):74-81. Epub 2015 May 25.

Department of Biology, Kazerun Branch, Islamic Azad University, Kazerun, Iran.

We studied the protective effect of Satureja khuzestanica essential oil (SKEO) against damage caused by busulfan on testis in male mice. The NMRI mice (n = 40) were assigned to four groups including: G1: control, G2: treated with busulfan for 4 days (3.2 mg kg(-1)), G3: receive busulfan (4 days, 3. Read More

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February 2016

Antimicrobial activity of seven essential oils from Iranian aromatic plants against common causes of oral infections.

Jundishapur J Microbiol 2015 Feb 19;8(2):e17766. Epub 2015 Feb 19.

Department of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, IR Iran.

Background: Over the past two decades, there has been a growing trend in using oral hygienic products originating from natural resources such as essential oils (EOs) and plant extracts. Seven aromatic plants used in this study are among popular traditional Iranian medicinal plants with potential application in modern medicine as anti-oral infectious diseases.

Objectives: This study was conducted to determine the chemical composition and antimicrobial activities of essential oils from seven medicinal plants against pathogens causing oral infections. Read More

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February 2015

Evaluation of Repellency Effect of Essential Oils of Satureja khuzestanica (Carvacrol), Myrtus communis (Myrtle), Lavendula officinalis and Salvia sclarea using Standard WHO Repellency Tests.

J Arthropod Borne Dis 2014 18;8(1):60-8. Epub 2013 Dec 18.

National Health Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Using special lotions and repellent sprays on skin is one of the effective methods to prevent Arthropods biting which was verified in this study.

Methods: Essential oils of four plants (Satureja khuzestanica, Salvia sclarea, Lavendula officinalis and Myrtus communis) were separately extracted by Clevenger used hydro distillation method. Then separated solutions with 10%, 20% and 40% concentrations of essential oils of plants in 99. Read More

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January 2015

Hepatoprotective effect of satureja khuzestanica essential oil and vitamin e in experimental hyperthyroid rats: evidence for role of antioxidant effect.

Iran J Med Sci 2014 Sep;39(5):459-66

Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Hyperthyroidism is associated with liver oxidative stress causing liver dysfunction in many hyperthyroid patients. The hepatoprotective effect of Satureja Khuzestanica Essential Oil (SKEO), as herbal origin antioxidant and anti-inflammatory agent on the hyperthyroidism induced hepatotoxicity and oxidative stress is investigated.

Methods: Adult male sprague dawley rats were divided into categories of; control (group C), hyperthyroid (group H), hyperthyroid with olive oil (group H+O), hyperthyroid with vitamin E (group H+E), hyperthyroid with SKEO (group H+S), combination of hyperthyroid with vitamin E and SKEO (group H+S+E). Read More

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September 2014

Characterization of Satureja khuzestanica leaf as a herbal medicine.

Microsc Microanal 2014 Oct 26;20(5):1425-35. Epub 2014 Aug 26.

1Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL),Pharmacological Sciences Group, Faculty of Pharmacy,University of Lisbon, Av. Prof. Gama Pinto,1649-019 Lisbon,Portugal.

Dried leaves of Satureja khuzestanica Jamzad are a popular herbal medicine and dental anesthetic among the nomadic inhabitants of southwestern Iran. The present study establishes criteria for identification of S. khuzestanica dried whole, fragmented and powdered leaves for specification as a herbal substance using macroscopic and microscopic characterization. Read More

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October 2014

Hepatoprotective and Hypolipidemic Effects of Satureja Khuzestanica Essential Oil in Alloxan-induced Type 1 Diabetic Rats.

Iran J Pharm Res 2012 ;11(4):1219-26

Department of Biochemistry, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. ; Razi Herbal Researches Center, Lorestan University of Medical Sciences, Khorramabad, Iran.

In the present study, we examined the antioxidative activities of Satureja khuzestanica essential oil (SKE) and possible protective effect of SKE on lipid profile, atherogenic index and liver enzyme markers in Alloxan-induced Type 1 diabetic rats. Thirty male rats were randomly divided into three groups; group one as control, group two diabetic untreatment, and group three treatments with SKE by 500 ppm in drinking water, respectively. Diabetes was induced in the second and third groups by alloxan injection subcutaneously. Read More

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November 2013

Satureja khuzestanica prevents the development of morphine analgesic tolerance through suppression of spinal glial cell activation in rats.

J Nat Med 2015 Apr 14;69(2):165-70. Epub 2013 Aug 14.

Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center (KNRC), Kerman University of Medical Sciences, Kerman, Iran,

Glial cell activation and oxidative stress are important factors in the induction of opioid side effects such as tolerance and dependence. It has been demonstrated that Satureja khuzistanica extract (SKE) has antioxidative, antinociceptive and anti-inflammatory properties; however, its influences on opioid analgesic tolerance have not yet been clarified. Adult male Wistar rats were rendered analgesic-tolerant by injection of 10 mg/kg morphine twice daily for 8 days. Read More

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Scolicidal effects of Olea europaea and Satureja khuzestanica extracts on protoscolices of hydatid cysts.

Korean J Parasitol 2012 Mar 6;50(1):53-6. Epub 2012 Mar 6.

Division of Parasitology, Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorram Abad, Iran.

Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of Satureja khuzestanica leaves and aqueous extracts of Olea europaea leaves on hydatid cyst protoscolices. Read More

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Satureja khuzestanica attenuates apoptosis in hyperglycemic PC12 cells and spinal cord of diabetic rats.

J Nat Med 2013 Jan 2;67(1):61-9. Epub 2012 Mar 2.

Kerman University of Medical Sciences, Kerman, Iran.

Several studies have indicated the involvement of oxidative stress and high glucose-induced cell death in the development of diabetic neuropathy. Satureja khuzestanica has been recommended in the literature as a remedy for the treatment of diabetes, and also contains antioxidant agents. Here, we investigated the possible neuroprotective effects of Satureja khuzestanica extract (SKE) on in vitro and in vivo models of diabetic neuropathy pain. Read More

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January 2013