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Int J Dermatol 2021 Jan 29;60(1):60-69. Epub 2020 Sep 29.

Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Prompt management of acute graft-versus-host disease (GVHD) may prevent its morbidity and mortality. Maculopapular (MP) eruption is a presenting sign of acute GVHD, but differentiation from other causes of MP rash is challenging.

Methods: A retrospective study was conducted among patients developing MP eruptions after allogeneic hematopoietic stem cell transplantation. Read More

World Neurosurg 2019 Dec 11;132:347-355. Epub 2019 Sep 11.

Department of Pathology, Medical College of Georgia at Augusta University, Augusta, Georgia, USA. Electronic address:

Background: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognized epileptogenic neuroepithelial tumor. Despite its distinctiveness, its polymorphous histology and the nature of its oligodendrocyte-like cells remain unclear.

Case Description: A 30-year-old, right-handed man was diagnosed with intractable epilepsy since 22 years of age. Read More

Int J Dermatol 2019 Oct 21;58(10):1199-1201. Epub 2018 Sep 21.

Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.

JFMS Open Rep 2018 Jul-Dec;4(2):2055116918786598. Epub 2018 Jul 23.

Veterinary Clinical Sciences, University of Minnesota, St Paul, MN, USA.

Case Summary: A 9-year-old male neutered Devon Rex cat presented with bilaterally symmetrical ulcerative lesions with mucopurulent exudate that developed rapidly. The lesions were apparent on the axillae, ventral abdomen and inguinal areas. The cat was systemically well. Read More

Clin Cancer Res 2017 04 18;23(8):2093-2104. Epub 2016 Nov 18.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Primary vulvar melanoma (PVM) is the second most common vulvar malignancy. Despite their distinct anatomic site and unique molecular-genetic alterations, PVMs are staged according to the American Joint Committee on Cancer (AJCC) guidelines for primary cutaneous melanomas (PCM). However, whether parameters derived for PCM also apply to PVM remain a critical yet largely unexplored clinical question. Read More

Ann Surg Oncol 2016 Feb;23(2):579-84

Background: Sentinel lymph node biopsy (SLNB) is a sensitive test for detecting subclinical nodal metastatic disease in patients with melanoma without evidence of lymph node involvement. The prognostic significance of SLN positivity in patients with melanoma >4 mm thick (T4) is unclear. The survival curves in the current AJCC staging system suggest that the status of the SLN is not predictive of outcome for patients with T4 melanoma. Read More

J Cutan Pathol 2015 Jan 29;42(1):56-60. Epub 2014 Dec 29.

Department of Pathology, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.

Atypical fibroxanthoma (AFX) is a cutaneous neoplasm of uncertain etiology that develops on sun-exposed regions of elderly males. It is widely considered to act indolently, despite its highly malignant cytologic features. Reports of metastatic AFX are very rare, and recurrence is uncommon. Read More

Am J Surg Pathol 2014 Aug;38(8):1058-70

Departments of *Pathology §Radiology †The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD Departments of ‡Pathology ¶Neurological Surgery, University of California San Francisco School of Medicine, San Francisco, CA ∥Hospital Pathology Associates, Minneapolis, St Paul, MN #University of Arizona, College of Medicine, Phoenix, AZ.

Oligodendrogliomas are an important adult form of diffuse gliomas with a distinctive clinical and genetic profile. Histologically similar tumors occurring rarely in children are incompletely characterized. We studied 50 patients with oligodendrogliomas (median age at diagnosis 8 y, range 7 mo to 20 y). Read More

Appl Immunohistochem Mol Morphol 2014 Jan;22(1):57-64

Cutaneous melanoma in young patients is rare with increasing incidence. It is not clear whether the etiology and clinical outcome are similar to cutaneous melanoma in the elderly. Mutations in BRAF gene in patients with cutaneous melanoma, in general, range in frequency from 20% to 80%; however, the status and clinical significance of BRAF mutations in the young population have not been evaluated. Read More

Melanoma Res 2012 Oct;22(5):362-7

Department of Dermatology, University of Tsukuba, Ibaraki, Japan.

The benefit of a sentinel lymph node (SLN) biopsy and adjuvant therapy for patients with thick (>4 mm) melanoma has not been well studied in the Asian population. We examined the benefit of an SLN biopsy and adjuvant therapy on prognosis in Japanese patients with thick melanoma. A review of the melanoma database collected from 26 institutions in Japan identified 291 patients with thick melanoma between 2005 and 2010. Read More

An Bras Dermatol 2011 Mar-Apr;86(2):215-21

Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.

Background: The incidence of melanoma cutaneous and the mortalities rates are rising in most countries worldwide.

Objective: to describe the histopathological characteristics of cutaneous melanoma, according to the criteria established by the Brazilian Group of Melanoma, and to evaluate early diagnosis in a cancer treatment referral center.

Methods: we performed a cross-sectional descriptive study of cases of primary cutaneous melanoma identified after excisional biopsy and processed at the pathology laboratory of Complexo Hospitalar Santa Casa between Jan 1st 2000 and Jan 15th 2005. Read More

Head Neck 2011 May 19;33(5):661-7. Epub 2010 Oct 19.

Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Background: The aim of the present analysis was to retrospectively evaluate outcomes in patients with cutaneous angiosarcoma of the face/scalp treated curatively with surgery, radiation therapy (RT), or a combination of surgery and RT.

Methods: In all, 70 patients with nonmetastatic angiosarcoma underwent surgery, RT, or combined-modality therapy. Of these, 20 patients (29%) were treated with surgery alone, 27 patients (39%) with RT alone, and 23 patients (33%) with combined-modality therapy; 44 patients received chemotherapy, either neoadjuvantly or adjuvantly or both. Read More

Ann Surg Oncol 2009 May 18;16(5):1176-83. Epub 2009 Feb 18.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Background: Microscopic satellitosis in melanoma is uncommon. The role of regional basin staging/therapy in patients with this high-risk feature has not been well defined.

Methods: Patients presenting from 1996 to 2005 with clinically localized melanoma containing microscopic satellitosis were identified from a prospective, single-institution database. Read More

J Vet Intern Med 2007 Jul-Aug;21(4):846-52

Tufts Cummings School of Veterinary Medicine, N. Grafton, MA, USA.

Background: Eastern equine encephalitis (EEE) virus is a mosquito-borne togavirus (alphavirus) that causes severe (often fatal) encephalitis in many mammalian species, but it has not been reported previously in South American camelids.

Hypothesis: South American camelids can become naturally infected with EEE virus and show encephalitic signs similar to those observed in other affected species.

Animals: Nine cases (8 alpacas and 1 llama, aged 3. Read More

Nihon Shokakibyo Gakkai Zasshi 1996 Mar;93(3):167-75

Department of Surgery, Ishikawaken Saiseikai Kanazawa Hospital, Japan.

We produced acute biliary reflux pancreatitis by an injection of auto-bile in 31 young mongrel dogs. We divided into control group (n = 10), catalase administration group (B1 group, n = 17) and no-administration group (B2 group, n = 14). We studied the histologic changes of the brain tissue in those groups. Read More

Hua Xi Yi Ke Da Xue Xue Bao 1992 Sep;23(3):314-7

Lanzhou Medical College.

A comparative ultrastructural investigation of the hypothalamic suprachiasmatic nuclei (SCN) of young, adult and senescent SD male rats was carried out. The neurons and neuroglial cells in SCN of the senile rats displayed more lipofuscin (Lipo) accumulation in comparison with those of the younger animals. Golgi apparatus (Gol) of the three age groups converted from well-ordered cisternae to irregular ones with extensive dilatation and vacuolization. Read More