3 results match your criteria saponin sk-mel28

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Cell-based electrochemical cytosensor for rapid and sensitive evaluation of the anticancer effects of saponin on human malignant melanoma cells.

Bioelectrochemistry 2021 Aug 31;140:107813. Epub 2021 Mar 31.

Department of Bionano Engineering, Center for Bionano Intelligence Education and Research, Hanyang University, Ansan 426-791, South Korea. Electronic address:

Discovering new anticancer agents and analyzing their activities is a vital part of drug development, but it requires a huge amount of time and resources, leading to the increasing demands for more-effective techniques. Herein, a novel and simple cell-based electrochemical biosensor, referred to as a cytosensor, was proposed to investigate the electrochemical behavior of human skin malignant melanoma (SK-MEL28) cells and the anticancer effect of saponin on cell viability. To enhance both electrocatalytic properties and biocompatibility, gold nanoparticles were electrochemically deposited onto a conductive substrate, and poly-L-lysine was further added to the electrode surface. Read More

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Isolation and Structural Characterization of Echinocystic Acid Triterpenoid Saponins from the Australian Medicinal and Food Plant Acacia ligulata.

J Nat Prod 2017 10 4;80(10):2692-2698. Epub 2017 Oct 4.

Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia , Adelaide, South Australia 5000, Australia.

The Australian plant Acacia ligulata has a number of traditional food and medicinal uses by Australian Aboriginal people, although no bioactive compounds have previously been isolated from this species. Bioassay-guided fractionation of an ethanolic extract of the mature pods of A. ligulata led to the isolation of the two new echinocystic acid triterpenoid saponins, ligulatasides A (1) and B (2), which differ in the fine structure of their glycan substituents. Read More

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October 2017

Biological activity and LC-MS/MS profiling of extracts from the Australian medicinal plant Acacia ligulata (Fabaceae).

Nat Prod Res 2018 Mar 21;32(5):576-581. Epub 2017 Apr 21.

a School of Pharmacy and Medical Sciences, Quality Use of Medicines and Pharmacy Research Centre , Sansom Institute for Health Research, University of South Australia , Adelaide , Australia.

Acacia ligulata A.Cunn. ex Benth. Read More

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