26,829 results match your criteria salmon

The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition.

Int J Biol Macromol 2021 Apr 10. Epub 2021 Apr 10.

Department of Biology, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, Via Cintia, I-80126 Naples, Italy.

The superfamily of vertebrate ribonucleases, a large group of evolutionarily related proteins, continues to provide interesting structural and functional information. In particular, the crystal structure of SS-RNase-2 from Salmo salar (SS2), here presented, has revealed a novel auto-inhibition mechanism that enriches the number of inhibition strategies observed in some members of the family. Within an essentially unmodified RNase folding, the SS2 active site cleft is in part obstructed by the collapse of an extra pentapeptide inserted in the C-terminal region. Read More

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Effect of commercial wearables and digital behaviour change resources on the physical activity of adolescents attending schools in socio-economically disadvantaged areas: the RAW-PA cluster-randomised controlled trial.

Int J Behav Nutr Phys Act 2021 Apr 12;18(1):52. Epub 2021 Apr 12.

Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.

Background: There has been increasing interest in using wearable activity trackers to promote physical activity in youth. This study examined the short- and longer-term effects of a wearable activity tracker combined with digital behaviour change resources on the physical activity of adolescents attending schools in socio-economically disadvantaged areas.

Methods: The Raising Awareness of Physical Activity (RAW-PA) Study was a 12-week, multicomponent intervention that combined a Fitbit Flex (and accompanying app), and online digital behaviour change resources and weekly challenges delivered via Facebook. Read More

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The transcriptomic responses of Atlantic salmon (Salmo salar) to high temperature stress alone, and in combination with moderate hypoxia.

BMC Genomics 2021 Apr 12;22(1):261. Epub 2021 Apr 12.

Department of Ocean Sciences, Memorial University, St. John's, NL, A1C 5S7, Canada.

Background: Increases in ocean temperatures and in the frequency and severity of hypoxic events are expected with climate change, and may become a challenge for cultured Atlantic salmon and negatively affect their growth, immunology and welfare. Thus, we examined how an incremental temperature increase alone (Warm & Normoxic-WN: 12 → 20 °C; 1 °C week), and in combination with moderate hypoxia (Warm & Hypoxic-WH: ~ 70% air saturation), impacted the salmon's hepatic transcriptome expr\ession compared to control fish (CT: 12 °C, normoxic) using 44 K microarrays and qPCR.

Results: Overall, we identified 2894 differentially expressed probes (DEPs, FDR < 5%), that included 1111 shared DEPs, while 789 and 994 DEPs were specific to WN and WH fish, respectively. Read More

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Aladaip, beyond alara and towards personalized optimization for paediatric cone beam ct.

Int J Paediatr Dent 2021 Apr 12. Epub 2021 Apr 12.

Université de Paris, Orofacial Pathologies, Imaging and Biotherapies UR2496 Lab, F-92120, Montrouge, France.

ALARA is a well-known principle that has been used to identify optimization of x-ray exposure in the field of radiology since the seventies. While ALARA implies the responsibility to minimize radiation exposures to a level As Low As Reasonably Achievable, some years ago, a variation of the acronym, ALADA, was proposed which took into account the evolution of imaging technology and any related dose increases . Read More

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Higher mortality of the less suitable brown trout host compared to the principal Atlantic salmon host when infested with freshwater pearl mussel (Margaritifera margaritifera) glochidia.

Parasitol Res 2021 Apr 12. Epub 2021 Apr 12.

Norwegian Institute for Nature Research (NINA), Postboks 5685 Torgarden, 7485, Trondheim, Norway.

The freshwater pearl mussel (Margaritifera margaritifera) is a highly host-specific parasite, with an obligate parasitic stage on salmonid fish. Atlantic salmon (Salmo salar) and brown trout (Salmo trutta f. trutta and Salmo trutta f. Read More

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Gene and Transposable Element Expression Evolution Following Recent and Past Polyploidy Events in (Poaceae).

Front Genet 2021 25;12:589160. Epub 2021 Mar 25.

UMR CNRS 6553 Ecosystèmes, Biodiversité, Evolution (ECOBIO), Université de Rennes 1, Rennes, France.

Gene expression dynamics is a key component of polyploid evolution, varying in nature, intensity, and temporal scales, most particularly in allopolyploids, where two or more sub-genomes from differentiated parental species and different repeat contents are merged. Here, we investigated transcriptome evolution at different evolutionary time scales among tetraploid, hexaploid, and neododecaploid species (Poaceae, Chloridoideae) that successively diverged in the last 6-10 my, at the origin of differential phenotypic and ecological traits. Of particular interest are the recent (19th century) hybridizations between the two hexaploids (2 = 6 = 62) and (2 = 6 = 60) that resulted in two sterile F1 hybrids: × (2 = 6 = 62) in England and × (2 = 6 = 62) in France. Read More

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Endocrine Disruptor Impacts on Fish From Chile: The Influence of Wastewaters.

Front Endocrinol (Lausanne) 2021 25;12:611281. Epub 2021 Mar 25.

Biological Sciences, University of Calgary, Calgary, AB, Canada.

Industrial wastewaters and urban discharges contain complex mixtures of chemicals capable of impacting reproductive performance in freshwater fish, called endocrine-disrupting compounds (EDCs). In Chile, the issue was highlighted by our group beginning over 15 years ago, by analyzing the impacts of pulp and paper mill effluents (PPME) in the Biobio, Itata, and Cruces River basins. All of the rivers studied are important freshwater ecosystems located in the Mediterranean region of Central Chile, each with a unique fish biodiversity. Read More

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The importance of a functional approach on benthic communities for aquaculture environmental assessment: Trophic groups - A polychaete view.

Mar Pollut Bull 2021 Apr 8;167:112309. Epub 2021 Apr 8.

Escuela de Ciencias del Mar, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.

Polychaetes were studied to assess the effect of aquaculture activity on the seafloor. Very high biodiversity of species was recorded associated with aquaculture centres with Cirratulidae, Spionidae and Paraonidae families being the most diverse and abundant families. The spatial distribution of polychaete trophic groups was the best descriptor for detecting changes on the benthos. Read More

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Barriers and facilitators to implementing perinatal mental health care in health and social care settings: a systematic review.

Lancet Psychiatry 2021 Apr 7. Epub 2021 Apr 7.

Centre for Maternal and Child Health, City, University of London, London, UK.

The improvement of perinatal mental health formed part of WHO's Millennium Development Goals. Research suggests that the implementation of perinatal mental health care is variable. To ensure successful implementation, barriers and facilitators to implementing perinatal mental health services need to be identified. Read More

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QuickIsoSeq for Isoform Quantification in Large-Scale RNA Sequencing.

Methods Mol Biol 2021 ;2284:135-145

Pfizer Worldwide Research and Development, Cambridge, MA, USA.

RNA-sequencing (RNA-seq) is a powerful technology for transcriptome profiling. While most RNA-seq projects focus on gene-level quantification and analysis, there is growing evidence that most mammalian genes are alternatively spliced to generate different isoforms that can be subsequently translated to protein molecules with diverse or even opposing biological functions. Quantifying the expression levels of these isoforms is key to understanding the genes biological functions in healthy tissues and the progression of diseases. Read More

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January 2021

The Citizenship Advantage in Psychological Well-being: An Examination of the Hukou System in China.

Demography 2021 Feb;58(1):165-189

RAND Corporation, Santa Monica, CA, USA.

Given that Chinese migrants with rural hukou status are not considered full citizens in their urban destinations, rural-urban hukou conversion signifies full citizenship attainment in urban China. We assess causal effects of three major types of urban hukou attainment-merit-, policy-, and family-based hukou conversion-on migrants' psychological well-being in middle- and later-life. We further examine how hukou matters-how periods and hukou destinations alter the values of specific urban hukou and their psychological health implications for individuals. Read More

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February 2021

[Multiple myeloma in an elderly patient with history of breast cancer : the value of multidisciplinary oncogeriatric collaboration].

Rev Med Liege 2021 Apr;76(4):232-238

Service de Gériatrie, CHR Citadelle, Liège, Belgique.

As the prevalence of cancers increases with age, some elderly patients are confronted with multiple tumoural pathologies. The clinical case of a 70-year-old patient with adenocarcinoma of the breast and multiple myeloma complicated by severe renal failure illustrates the complexity of oncogeriatric management. The geriatric assessment makes it possible to detect frailty and provides assistance in the development of a personalized care plan while respecting the quality of life. Read More

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How ancestral subsistence strategies solve salmon starvation and the "protein problem" of Pacific Rim resources.

Am J Phys Anthropol 2021 Apr 8. Epub 2021 Apr 8.

Department of Anthropology, University of California, Davis, California, USA.

This article provides a theoretical treatment of hunter-gatherer diet and physiology. Through a synthesis of nutritional studies, informed by ethno-archaeological data, we examine the risk of protein-rich diets for human survival, and how societies circumvent "salmon starvation" in the northeastern Pacific Rim. Fundamental nutritional constraints associated with salmon storage and consumption counter long-standing assumptions about the engine of cultural evolution in the region. Read More

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The pharmacokinetics of [F]UCB-H revisited in the healthy non-human primate brain.

EJNMMI Res 2021 Apr 7;11(1):36. Epub 2021 Apr 7.

Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire Des Maladies Neurodégénératives, 18 Route du Panorama, 92265, Fontenay-aux-Roses, France.

Background: Positron Emission Tomography (PET) imaging of the Synaptic Vesicle glycoprotein (SV) 2A is a new tool to quantify synaptic density. [F]UCB-H was one of the first promising SV2A-ligands to be labelled and used in vivo in rodent and human, while limited information on its pharmacokinetic properties is available in the non-human primate. Here, we evaluate the reliability of the three most commonly used modelling approaches for [F]UCB-H in the non-human cynomolgus primate, adding the coupled fit of the non-displaceable distribution volume (V) as an alternative approach to improve unstable fit. Read More

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Skin bacteria of rainbow trout antagonistic to the fish pathogen Flavobacterium psychrophilum.

Sci Rep 2021 Apr 6;11(1):7518. Epub 2021 Apr 6.

Faculty of Marine Science and Technology, Fukui Prefectural University, 1-1 Gakuen-cho, Obama, Fukui, 917-0003, Japan.

Rainbow trout fry syndrome (RTFS) and bacterial coldwater disease (BCWD) is a globally distributed freshwater fish disease caused by Flavobacterium psychrophilum. In spite of its importance, an effective vaccine is not still available. Manipulation of the microbiome of skin, which is a primary infection gate for pathogens, could be a novel countermeasure. Read More

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Large inter-stock differences in catch size-at-age of mature Atlantic salmon observed by using genetic individual origin assignment from catch data.

PLoS One 2021 6;16(4):e0247435. Epub 2021 Apr 6.

Department of Biology, University of Turku, Turku, Finland.

Genetic individual assignment of river stock of origin of mixed stock catch fish offers a tool to analyze size differences among river stocks. Data on the genetically identified river stock of origin of individual fish from commercial mixed stock catches were used to compare the catch size-at-age of mature Atlantic salmon catch fish (Salmo salar) from different rivers in the Baltic Sea. In this application of genetic mixed stock modeling, individual assignments of the river stock of origin were analyzed together with length- and weight-at-age data for individual catch fish. Read More

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Rapid prototyping of flexible terahertz metasurfaces using a microplotter.

Opt Express 2021 Mar;29(6):8617-8625

Additive manufacturing is a promising tool for the rapid prototyping of terahertz metamaterials at low-cost. In this letter, a terahertz metamaterial is fabricated using a microplotter system on a flexible polyimide film. The limits of the rapid prototyping technique is investigated both experimentally and numerically in order to determine the spectral range accessible by the fabricated metamaterials. Read More

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Pharmacy, workplace or primary care? Where Australian adults get their influenza vaccines.

Aust N Z J Public Health 2021 Apr 5. Epub 2021 Apr 5.

Biosecurity Program, The Kirby Institute, University of New South Wales.

Objective: To estimate the proportion of influenza vaccines administered in non-medical settings in Australia in 2019 and identify factors associated with vaccination site.

Methods: We surveyed 1,444 Australian adults online in October 2019. To identify factors associated with vaccination site, we used Pearson's chi-square test. Read More

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Limits on performance and survival of juvenile sockeye salmon () during food deprivation: a laboratory-based study.

Conserv Physiol 2021 24;9(1):coab014. Epub 2021 Mar 24.

Fisheries and Oceans Canada, Cooperative Resource Management Institute, School of Resource and Environmental Management, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.

Long-distance migrations can be energetically demanding and can represent phases of high mortality. Understanding relationships between body condition and migratory performance can help illuminate the challenges and vulnerabilities of migratory species. Juvenile anadromous sockeye salmon () may migrate over 1000 km from their freshwater nursery habitats to estuary and ocean feeding grounds. Read More

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No more than meets the eye.

Eur J Intern Med 2021 Apr 1. Epub 2021 Apr 1.

Service de Médecine Interne, Maladies Infectieuses et Immunologie Clinique. Hôpital Robert Debré. Centre Hospitalier Universitaire Reims. France. Electronic address:

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Routine antiseptic baths and MRSA decolonization: diverse approaches across Singapore's acute-care hospitals.

J Hosp Infect 2021 Apr 1. Epub 2021 Apr 1.

Division of Infectious Diseases, National University Hospital, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

To determine the variation in practices on meticillin-resistant Staphylococcus aureus (MRSA) surveillance and management of MRSA-colonized patients amongst 17 acute healthcare facilities in Singapore, the Ministry of Health convened a sharing session with Infection Prevention and Control Leads. All hospitals practised close to universal MRSA entry swabbing in keeping with national policy. There were, however, major variations in the response to both positive and negative surveillance swabs across facilities including the role of routine antiseptic bathing and MRSA decolonization. Read More

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Persistent homology in two-dimensional atomic networks.

J Chem Phys 2021 Mar;154(12):124109

Department of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, South Parks Road, Oxford OX1 3QZ, United Kingdom.

The topology of two-dimensional network materials is investigated by persistent homology analysis. The constraint of two dimensions allows for a direct comparison of key persistent homology metrics (persistence diagrams, cycles, and Betti numbers) with more traditional metrics such as the ring-size distributions. Two different types of networks are employed in which the topology is manipulated systematically. Read More

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Quantity and Quality of Aquaculture Enrichments Influence Disease Epidemics and Provide Ecological Alternatives to Antibiotics.

Antibiotics (Basel) 2021 Mar 22;10(3). Epub 2021 Mar 22.

Department of Biological and Environmental Science, University of Jyvaskyla, P.O. Box 35, 40014 Jyvaskyla, Finland.

Environmental heterogeneity is a central component influencing the virulence and epidemiology of infectious diseases. The number and distribution of susceptible hosts determines disease transmission opportunities, shifting the epidemiological threshold between the spread and fadeout of a disease. Similarly, the presence and diversity of other hosts, pathogens and environmental microbes, may inhibit or accelerate an epidemic. Read More

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Molecular Evolution of Infectious Pancreatic Necrosis Virus in China.

Viruses 2021 Mar 16;13(3). Epub 2021 Mar 16.

Key Laboratory of Aquatic Animal Diseases and Immune Technology of Heilongjiang Province, Department of Aquatic Animal Diseases and Control, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China.

Passive virus surveillance was performed in twenty-nine salmon and trout farms from seven provinces and districts in China during the period 2017-2020. A total of 25 infectious pancreatic necrosis virus (IPNV) isolates were obtained, mainly from rainbow trout (). The molecular evolution of these Chinese IPNV isolates and the previously reported Chinese IPNV strains ChRtm213 and WZ2016 was analyzed, based on their VP2 gene coding region sequences (CDS). Read More

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Transcriptomic and Histopathological Effects of Bifenthrin to the Brain of Juvenile Rainbow Trout ().

Toxics 2021 Mar 5;9(3). Epub 2021 Mar 5.

Department of Environmental Sciences, University of California, Riverside, 2460A Geology, Riverside, CA 92521, USA.

The increased global use of pyrethroids raises concern for non-target aquatic species. Bifenthrin, among the most predominantly detected pyrethroids in the environment, is frequently measured in water samples above concentrations reported to induce neuroendocrine and neurotoxic effects to several threatened and endangered fish species, such as the Chinook salmon and steelhead trout. To better characterize the neurotoxic effect of bifenthrin to salmonids, rainbow trout were treated with environmentally relevant concentrations of bifenthrin (15 and 30 ng/L) for two weeks and assessed for changes in transcriptomic profiles and histopathological alterations. Read More

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Modulation of Gene Expression in a Sterile Atopic Dermatitis Model and Inhibition of Adhesion by Fucoidan.

Dermatopathology (Basel) 2021 Mar 25;8(2):69-83. Epub 2021 Mar 25.

Marinova Pty Ltd., 249 Kennedy Drive, Cambridge, TAS 7170, Australia.

Atopic dermatitis is a multifactorial pathology that includes perturbations of gene expression and increased adhesion of Fucoidans are seaweed-derived sulfated fucose-rich polysaccharides that are known to be anti-inflammatory and may inhibit adhesion of pathogens. Fucoidan was assessed for effects on gene expression of an in vitro 3D model of atopic dermatitis. It was also assessed for inhibitory effects on the adhesion of bacteria onto 3D reconstructed skin. Read More

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