7,525 results match your criteria rutosides


A combined approach based on matrix solid-phase dispersion extraction assisted by titanium dioxide nanoparticles and liquid chromatography to determine polyphenols from grape residues.

J Chromatogr A 2021 Mar 31;1644:462128. Epub 2021 Mar 31.

Analytical Chemistry Department. Faculty of Chemistry. Universidad Complutense de Madrid. 28040-Madrid, Spain.

A simple and efficient low-cost matrix solid phase dispersion (MSPD) extraction assisted by TiO nanoparticles and diatomaceous earth has been developed for the extraction of phenolic compounds from grape and grape pomace wastes. Experimental conditions for MSPD extraction were optimized by a factorial design and a surface response methodology. The simultaneous identification and quantification of eight main natural polyphenols (caffeic, p-coumaric, dihydroxybenzoic and gallic acid, rutin, resveratrol, quercetin and catechin) was possible by combining MSPD and capillary liquid chromatography coupled to a diode array detection and a mass simple quadrupole analyzer (cLC-DAD-MS). Read More

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Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment.

Pharmacol Res 2021 Apr 9:105604. Epub 2021 Apr 9.

LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal. Electronic address:

Diabetes mellitus is one of the biggest health emergencies of the 21 century worldwide, characterized by deficiency in insulin secretion and/or action, leading to hyperglycemia. Despite the currently available antidiabetic therapeutic options, 4.2 million people died in 2019 due to diabetes. Read More

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Enzymatic acylation of rutin with benzoic acid ester and lipophilic, antiradical, and antiproliferative properties of the acylated derivatives.

J Food Sci 2021 Apr 12. Epub 2021 Apr 12.

Department of Food Science and Engineering, Jinan University, Guangzhou, Guangdong, China.

Rutin (3',4',5,7-tetrahydroxy-flavone-3-rutinoside) was enzymatically acylated with benzoic acid and its esters (methyl benzoate and vinyl benzoate) using Thermomyces lanuginosus lipase (Lipozyme TLIM). The acylation reaction was optimized by varying the reaction medium, reaction temperature, acyl donor, substrate molar ratio, and reaction time. The highest conversion yield (76%) was obtained in tert-amyl alcohol (60 °C, 72 hr) using vinyl benzoate (molar ratio of 1:10) as acyl donor. Read More

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Rutin Improves Cardiac and Erythrocyte Membrane-Bound ATPase Activities in Male Rats Exposed to Cadmium Chloride and Lead Acetate.

Biol Trace Elem Res 2021 Apr 12. Epub 2021 Apr 12.

Cardiovascular Physiology Unit, Department of Physiology, Bowen University, P.M.B 284, Iwo, Osun State, Nigeria.

Cardiovascular diseases have been associated with cadmium (Cd) and lead (Pb). Impaired Ca and Na/K-ATPase activities have also been linked to hemolytic and cardiovascular disorders. This study investigated the effect of rutin on Cd and/or Pb-induced cardiac and erythrocyte disorders in male rats. Read More

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Antibacterial, anti-inflammatory, analgesic, and hemostatic activities of (L.) merr.

Food Sci Nutr 2021 Apr 28;9(4):2191-2202. Epub 2021 Feb 28.

Allan H. Conney Laboratory for Anticancer Research School of Biomedical and Pharmaceutical Sciences Guangdong University of Technology Guangzhou China.

(L.) Merr (AT) is a medicinal and edible plant with high nutritional value. The biological activity of (L. Read More

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Polyphenols, Flavonoids, and Antioxidant Activity Involved in Salt Tolerance in Wheat, and Their Amphidiploids.

Front Plant Sci 2021 25;12:646221. Epub 2021 Mar 25.

Department of Agronomy and Plant Breeding, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.

spp. is the closest genus to wheat ( spp.), which makes great candidates to exhibit precursors of wheat features. Read More

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Hydropriming Applied on Fast Germinating Miller Seeds: Impact on Pre-germinative Metabolism.

Front Plant Sci 2021 25;12:639336. Epub 2021 Mar 25.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.

Seed priming can circumvent poor germination rate and uniformity, frequently reported in eggplant ( L.) and its crop wild relatives (CWRs). However, there is still a gap of knowledge on how these treatments impact the pre-germinative metabolism in a genotype- and/or species-dependent manner. Read More

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Novel bayberry-and-honeycomb-like magnetic surface molecularly imprinted polymers for the selective enrichment of rutin from Sophora japonica.

Food Chem 2021 Mar 29;356:129722. Epub 2021 Mar 29.

School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.

Rutin (RT), a widely distributed natural flavonoid compound, has been generally utilized as an important active ingredient owing to its considerable biomedical and economic value. Inspired by the structure features of densely-packed bayberry and well-orientated honeycomb, a novel type of magnetic molecularly imprinted polymers (HB-TI-MMIPs) with abundant high-affinity and uniformly-distributed binding sites was rationally constructed for the selective enrichment of RT from Sophora japonica. The polymerization conditions, physicochemical properties, and adsorption performance of the imprinted nanomaterials were systematically investigated. Read More

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White Tip Silver Needle (Slightly Fermented White Tea) Flavonoids Help Prevent Aging via Antioxidative and Anti-Inflammatory Effects.

Drug Des Devel Ther 2021 31;15:1441-1457. Epub 2021 Mar 31.

Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing, 400067, People's Republic of China.

Aim: White tip silver needle, a slightly fermented white tea, is abundant in flavonoids, and it has great significance in terms of D-galactose/lipopolysaccharide-induced aging in mice.

Methods: We analyzed the antioxidant capacity of white tip silver needle flavonoids (WTSNF) in vitro, assessed the effects of WTSNF on organ indexes, pathological changes, liver function indexes, biochemical indicators, molecular biological indicators, and genes related to oxidation and inflammation.

Results: Ultra-high performance liquid chromatography-tandem mass spectrometry results showed that WTSNF contained baicalin, kaempferol, kaempferide, quercetin, isorhamnetin, lespenephryl, and rutin. Read More

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Characterization, techno-functional properties, and encapsulation efficiency of self-assembled β-lactoglobulin nanostructures.

Food Chem 2021 Mar 30;356:129719. Epub 2021 Mar 30.

Graduate Program in Chemistry Engineering, Federal University of São João del-Rei, Campus Alto Paraopeba, MG 443, km 7, 36420-000 Ouro Branco, MG, Brazil; Department of Chemistry, Biotechnology and Bioprocess Engineering, Federal University of São João del-Rei, Campus Alto Paraopeba, MG 443, km 7, 36420-000 Ouro Branco, MG, Brazil. Electronic address:

Whey is a cheese co-product with high protein content used in the food industry due to its techno-functional properties and nutritive value. This study aims to optimize the production of β-lactoglobulin (β-lg) nanostructures, to characterize their techno-functional properties and stability, and to apply them as a carrier of bioactive molecules. Box-Behnken planning was applied to determine the best conditions to obtain the β-lg nanostructure, which consists in treatment at 100 °C in NaCl 50 mmol·L for 60 min. Read More

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Unravelling the anthelmintic bioactives from Jasminum grandiflorum L. subsp. Floribundum adopting in vitro biological assessment.

J Ethnopharmacol 2021 Apr 5:114083. Epub 2021 Apr 5.

Departement of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, P.O. Box 12211, Egypt. Electronic address:

Ethnopharmacological Relevance: Jasminum grandiflorum L. is a medicinal plant widely used in the traditional system of Medicine as an anthelmintic in ringworm infections, for treating ulcers, stomatitis, skin diseases, and wounds.

Aim Of The Study: The emergence of resistance by different parasites to currently used chemicals has been reported. Read More

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In silico analysis of the potential mechanism of a preventive Chinese medicine formula on Coronavirus Disease 2019.

J Ethnopharmacol 2021 Apr 5:114098. Epub 2021 Apr 5.

Provincial Key Laboratory of TCM Diagnostics, Hunan University of Chinese Medicine, Changsha, China; Hunan Engineering Technology Research Center for Medicinal and Functional Food, Hunan University of Chinese Medicine, Changsha, China; Key Laboratory of TCM Heart and Lung Syndrome Differentiation &; Medicated Diet and Dietotherapy, Hunan University of Chinese Medicine, Changsha, China. Electronic address:

Ethnopharmacological Relevance: With the spread of Coronavirus Disease 2019 (COVID-19), combination with traditional Chinese medicine (TCM) has been widely used as a prevention and therapy strategy in China. Xin guan No.1 (XG-1) prescription is a preventive formula recommended by the Hunan Provincial Administration of TCM to prevent the pandemic of COVID-19. Read More

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Application field of VOXEL-MAN Tempo 3D virtual reality simulator in surgery of pars petrosa of temporal bone

Orv Hetil 2021 04 7;162(16):623-628. Epub 2021 Apr 7.

1 Szegedi Tudományegyetem, Általános Orvostudományi Kar, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika, Szeged, Tisza Lajos krt. 111., 6725.

Összefoglaló. Bevezetés: Az emberi sziklacsont a halántékcsont része, egy bonyolult és változatos anatómiai felépítésű struktúra. A sziklacsonton végzett beavatkozások előtt, a műtéti szövődmények megelőzése érdekében, nélkülözhetetlen a biztos anatómiai tudás és kézügyesség megszerzése, valamint az egyes műtéti lépések és mozdulatok begyakorlása. Read More

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The chromosome-level Hemerocallis citrina Borani genome provides new insights into the rutin biosynthesis and the lack of colchicine.

Hortic Res 2021 Apr 7;8(1):89. Epub 2021 Apr 7.

Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha, Hunan, 410128, China.

Hemerocallis citrina Borani (huang hua cai in Chinese) is an important horticultural crop whose flower buds are widely consumed as a delicious vegetable in Asia. Here we assembled a high-quality reference genome of H. citrina using single-molecule sequencing and Hi-C technologies. Read More

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Characterization and quantification of bioactive compounds from Ilex paraguariensis residue by HPLC-ESI-QTOF-MS from plants cultivated under different cultivation systems.

J Food Sci 2021 Apr 6. Epub 2021 Apr 6.

Department of Agroindustrial Science and Technology, Faculty of Engineering Eliseu Maciel, Federal University of Pelotas (UFPEL), Pelotas, Rio Grande do Sul, CEP 96010-610, Brazil.

Ilex paraguariensis is a perennial plant used in the production of mate tea, "chimarrão" and "tererê," cosmetics, and other food products. Its leaves are harvested every 12 or 18 months. Approximately 2 to 5 tons of residue are generated per hectare during the harvest. Read More

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Fluorescence spectroscopy and molecular docking analysis of the binding of Lactobacillus acidophilus GIM1.208 β-glucosidase with quercetin glycosides.

Enzyme Microb Technol 2021 May 11;146:109761. Epub 2021 Feb 11.

School of Liquor & Food Engineering, Guizhou University, National Forestry and Grassland Bureau Prickly Pear Engineering Technology Research Center, Key Laboratory of Agricultural and Animal Products Store and Processing of Guizhou Province, Guiyang, 550025, China.

Lactobacillus acidophilus is an important probiotic. The β-glucosidase produced by L. acidophilus GIM1. Read More

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Molecular mechanisms involved in the prevention and reversal of ketamine-induced schizophrenia-like behavior by rutin: the role of glutamic acid decarboxylase isoform-67, cholinergic, Nox-2-oxidative stress pathways in mice.

Mol Biol Rep 2021 Apr 3. Epub 2021 Apr 3.

Neuropharmacology Unit, Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.

Mounting evidences have shown that nicotinamide adenine dinucleotide phosphate oxidase-2 (Nox-2) pathway modifies glutamic-acid decarboxylase-67 (GAD) (GABAergic enzyme) and cholinergic systems via oxidative-nitrergic mechanisms in schizophrenia pathology. Rutin, a neuroactive antioxidant compound, with proven neuroprotective property has been shown to reduce schizophrenic-like behavior in mice. This study sought to investigate the mechanisms of action of the psychopharmacological activity of rutin in the preventive and reversal effects of ketamine-induced schizophrenic-like behavior, oxidative-nitrergic stress, cholinergic and GABAergic derangements in mice. Read More

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Productivity and Post-Harvest Fungal Resistance of Hot Pepper as Affected by Potassium Silicate, Clove Extract Foliar Spray and Nitrogen Application.

Plants (Basel) 2021 Mar 30;10(4). Epub 2021 Mar 30.

Department of Plant Pathology, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria 21545, Egypt.

In the present study, growth and productivity of hot pepper planted in the two successive summer seasons of 2017 and 2018 were evaluated under the effect of foliar spray of variable doses of potassium silicate (PS), and clove water extract (CWE) with different rates of nitrogen (N) fertilization application. The post-harvest resistance of hot pepper fruits to fungal infection, was also evaluated. Maximum plant height was achieved with the application of the highest rates of N, PS and CWE, while the intermediate rates were sufficient to reach the maximum number of branches, the highest leaf dry matter and chlorophyll accumulation. Read More

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Maillard Reaction Products in Gluten-Free Bread Made from Raw and Roasted Buckwheat Flour.

Molecules 2021 Mar 4;26(5). Epub 2021 Mar 4.

Department of Food Technology of Plant Origin, Poznań University of Life Sciences, 31 Wojska Polskiego St., 60-624 Poznań, Poland.

The formation of Maillard reaction products (MRPs) in gluten-free bread made from roasted and raw buckwheat flour was examined. The levels of phenolic compounds such as flavonoids (catechin, naringenin, quercetin, rutin, and others) and phenolic acids (like 4-hydroxybenzoic, caffeic, dihydroxybenzoic, ferulic, gallic, syringic, vanillic, and -coumaric) were measured using reversed-phase ultra-high performance liquid chromatography-electrospray ionization mass spectrometry (RP-UHPLC-ESI-MS). Early and advanced Maillard reaction products were analyzed using HPLC, whereas spectrofluorimetric analysis was used to determine the levels of fluorescent intermediate compounds (FIC). Read More

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Phytochemical Profiling of Methanolic Fruit Extract of Ait. by LC-MS/MS Analysis and Evaluation of Its Antioxidant and Antimicrobial Activity.

Plants (Basel) 2021 Mar 13;10(3). Epub 2021 Mar 13.

Nutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, Ourense Campus, University of Vigo, E32004 Ourense, Spain.

Ait. (Rubiaceae) is also known as Indian Boxwood is a small deciduous tree often growing in southern states of India. In the present study, phytochemical profiling of methanolic extract of fruits were carried out using FTIR and LC-MS/MS analysis. Read More

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Chemical Composition, Antioxidant and Cytoprotective Potentials of Leaf Extracts: A Comparison of Supercritical Fluid and Conventional Extraction Methods.

Molecules 2021 Mar 9;26(5). Epub 2021 Mar 9.

School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.

The leaves of (CP) are rich in natural antioxidants. has traditionally been used to treat various ailments, including skin diseases. This study aims to decipher the antioxidant effects and phytochemical content of different CP leaf extracts (CPEs) obtained using supercritical carbon dioxide (scCO) and conventional extraction methods. Read More

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Electrochemical Sensor for Determination of Various Phenolic Compounds in Wine Samples Using FeO Nanoparticles Modified Carbon Paste Electrode.

Micromachines (Basel) 2021 Mar 17;12(3). Epub 2021 Mar 17.

Department of Biomedical Engineering, Near East University, Near East Boulevard, 99138 Nicosia, Cyprus.

Phenolic compounds contain classes of flavonoids and non-flavonoids, which occur naturally as secondary metabolites in plants. These compounds, when consumed in food substances, improve human health because of their antioxidant properties against oxidative damage diseases. In this study, an electrochemical sensor was developed using a carbon paste electrode (CPE) modified with FeO nanoparticles (MCPE) for the electrosensitive determination of sinapic acid, syringic acid, and rutin. Read More

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Quantitative Analysis of Rutin by HPTLC and In Vitro Antioxidant and Antibacterial Activities of Phenolic-Rich Extracts from .

Plants (Basel) 2021 Mar 3;10(3). Epub 2021 Mar 3.

CONACYT-Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional Unidad Michoacán, Instituto Politécnico Nacional, Jiquilpan 59510, Michoacan, Mexico.

A. Gray, like other wild plants of the genus , has been used in herbal medicine. There is information for other species of the genus related to their phenolic content, antioxidant capacity, and isolation of bioactive compounds with antimicrobial activity. Read More

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The Antioxidant Effect of Curcumin and Rutin on Oxidative Stress Biomarkers in Experimentally Induced Periodontitis in Hyperglycemic Wistar Rats.

Molecules 2021 Mar 2;26(5). Epub 2021 Mar 2.

Dental Medicine Department, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania.

Background: There is a growing interest in the correlation between antioxidants and periodontal disease. In this study, we aimed to investigate the effect of oxidative stress and the impact of two antioxidants, curcumin and rutin, respectively, in the etiopathology of experimentally induced periodontitis in diabetic rats.

Methods: Fifty Wistar albino rats were randomly divided into five groups and were induced with diabetes mellitus and periodontitis: (1) (CONTROL)-control group, (2) (DPP)-experimentally induced diabetes mellitus and periodontitis, (3) (DPC)-experimentally induced diabetes mellitus and periodontitis treated with curcumin (C), (4) (DPR)-experimentally induced diabetes mellitus and periodontitis treated with rutin (R) and (5) (DPCR)-experimentally induced diabetes mellitus and periodontitis treated with C and R. Read More

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In Vitro Gastrointestinal Digestion Impact on the Bioaccessibility and Antioxidant Capacity of Bioactive Compounds from Tomato Flours Obtained after Conventional and Ohmic Heating Extraction.

Foods 2021 Mar 7;10(3). Epub 2021 Mar 7.

CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.

In times of pandemic and when sustainability is in vogue, the use of byproducts, such as fiber-rich tomato byproducts, can be an asset. There are still no studies on the impact of extraction methodologies and the gastrointestinal tract action on bioactive properties. Thus, this study used a solid fraction obtained after the conventional method (SFCONV) and a solid fraction after the ohmic method (SFOH) to analyze the effect of the gastrointestinal tract on bioactive compounds (BC) and bioactivities. Read More

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Preparative separation of five polyphenols from the fruits of Sorbus pohuashanensis Hedl. by high-speed counter-current chromatography.

J Chromatogr B Analyt Technol Biomed Life Sci 2021 Mar 5;1172:122620. Epub 2021 Mar 5.

School of Pharmaceutical Sciences, Liaoning University, Shenyang 110036, PR China; Natural Products Pharmaceutical Engineering Technology Research Center of Liaoning Province, Shenyang 110036, PR China. Electronic address:

The fruits of Sorbus pohuashanensis Hedl. (S. pohuashanensis) are rich in polyphenols with many beneficial effects such as anti-inflammatory, anti-tussive, anti-asthmatic and anti-cancer. Read More

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