Nutrients 2021 Mar 19;13(3). Epub 2021 Mar 19.
Faculty of Science and Technology, Free University of Bozen, 39100 Bolzano, Italy.
This work aimed to define the microbial consortia that are able to digest gluten into non-toxic and non-immunogenic peptides in the human gastrointestinal tract.
Methods: 131 out of 504 tested and lactic acid bacteria, specifically (64), lactobacilli (63), (1), and (3), showed strong gastrointestinal resistance and were selected for their PepN, PepI, PepX, PepO, and PepP activities toward synthetic substrates. Based on multivariate analysis, 24 strains were clearly distinct from the other tested strains based on having the highest enzymatic activities. Read More