Int J Radiat Oncol Biol Phys 2021 Aug 30. Epub 2021 Aug 30.
Department of Radiation Oncology, Rutgers University, New Brunswick, NJ.
Objective: SBRT is increasingly used to treat a variety of oligometastatic histologies, but few data exist for ovarian cancer. Ablative SBRT dosing is challenging in sites like the abdomen, pelvis, and central thorax due to proximity and motion of organs-at-risk. A novel radiation delivery method, stereotactic magnetic-resonance-guided online-adaptive radiotherapy (SMART), may improve SBRT's therapeutic index through enhanced soft-tissue visualization, real-time non-ionizing imaging, and ability to adapt to the anatomy-of-the-day, with the goal of producing systemic-therapy-free intervals. Read More