20,618 results match your criteria risk 117


The impact of the Regional Partnership Grant program on adult recovery and well-being, and child safety, permanency, and well-being outcomes.

Child Abuse Negl 2021 Apr 10;117:105069. Epub 2021 Apr 10.

Mathematica, United States.

Background: Adult substance use contributes to high rates of child maltreatment, adverse parenting, and poor child well-being outcomes. The Children's Bureau in the Administration for Children and Families, U.S. Read More

View Article and Full-Text PDF

Benefit of chemotherapy in stage III nasopharyngeal carcinoma: Analysis of the surveillance, epidemiology, and end results database.

Oral Oncol 2021 Apr 9;117:105284. Epub 2021 Apr 9.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China; Department of Nasopharyngeal Carcinoma, Sun Yat-Sen University Cancer Center, Guangzhou 510060, China. Electronic address:

Objectives: Chemoradiotherapy is the standard treatment for locoregionally advanced nasopharyngeal carcinoma (NPC). We aimed to reveal factors associated with chemotherapy use and evaluate chemotherapy's benefit in patients with stage III NPC stratified by lymph node status.

Patients And Methods: Overall, 1452 patients with stage III NPC who underwent radiotherapy with (n = 1361) or without (n = 91) chemotherapy were identified in the SEER database. Read More

View Article and Full-Text PDF

Poor Validity of Functional Performance Tests to Predict Knee Injury in Female Soccer Players With or Without Anterior Cruciate Ligament Reconstruction.

Am J Sports Med 2021 Apr 12:3635465211002541. Epub 2021 Apr 12.

Unit of Physiotherapy, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

Background: Various tests have been developed to evaluate athletes' functional performance and for use as screening tools for injury prediction. Further validation of their accuracy to predict injury is needed.

Purpose: To investigate the validity of predetermined cutoffs used to differentiate between high- and low-risk players in different functional performance tests to predict (1) anterior cruciate ligament (ACL) injury or (2) severe traumatic knee injury in a cohort of female soccer players with a primary unilateral ACL reconstruction and a cohort of knee-healthy players. Read More

View Article and Full-Text PDF

Electronic cigarette use is negatively associated with body mass index: An observational study of electronic medical records.

Obes Sci Pract 2021 Apr 22;7(2):226-231. Epub 2020 Dec 22.

Department of Health Behavior School of Public Health University of Alabama at Birmingham Birmingham Alabama USA.

Objective: Vaping is advertised as a method to mitigate weight gain after smoking cessation; however, while there is an established inverse association between conventional tobacco use and body mass index (BMI), there is little research on the relationship between e-cigarettes and BMI. This research tested whether e-cigarette use was associated with BMI.

Methods: A secondary data analysis of 207,117 electronic medical records from the UAB was conducted. Read More

View Article and Full-Text PDF

Appropriate responses to potential child abuse: The importance of information quality.

Child Abuse Negl 2021 Apr 8;117:105062. Epub 2021 Apr 8.

School of Psychology, UNSW, Sydney, Australia.

Background: When people suspect a child or young person is experiencing, or at risk of, abuse or neglect, they have to decide how to respond. However, the under and over reporting of child welfare issues indicate that people may struggle to identify an appropriate response.

Objective: To develop scenarios (for future training and research purposes) that closely resemble the child welfare situations health/allied health practitioners encounter, and for which there is a reasonable level of child protection professional consensus as to what the appropriate response for each situation should be. Read More

View Article and Full-Text PDF

Validation and further development of a risk assessment instrument for child welfare.

Child Abuse Negl 2021 Apr 7;117:105047. Epub 2021 Apr 7.

Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, the Netherlands.

Background: Although many child maltreatment risk assessment instruments have been implemented in child welfare organizations, thorough studies on their predictive validity are scarce.

Objective: To examine (1) the predictive validity of a risk assessment instrument that has been widely implemented in the Netherlands, and to examine (2) whether the actuarial risk estimation could be improved and simplified to widen the instrument's applicability to different organizations serving different populations.

Participants And Setting: The sample comprised risk assessments (N = 3,681) performed for families enrolled at one of five child welfare agencies in the Netherlands between January 2015 and December 2017. Read More

View Article and Full-Text PDF

Cross-cultural adaptation of the Perceived Risk of HIV Scale in Brazilian Portuguese.

Health Qual Life Outcomes 2021 Apr 9;19(1):117. Epub 2021 Apr 9.

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Background: Valid and reliable instruments are needed to measure the multiple dimensions of perceived risk. The Perceived Risk of HIV Scale is an 8-item measure that assesses how people think and feel about their risk of infection. We set out to perform a cross-cultural adaptation of the scale to Brazilian Portuguese among key populations (gay, bisexual and other men who have sex with men and transgender/non-binary) and other populations (cisgender heterosexual men and cisgender women). Read More

View Article and Full-Text PDF

Performance of the graphite felt flow-through electrode in hexavalent chromium reduction using a single-pass mode.

J Hazard Mater 2021 Apr 1;416:125768. Epub 2021 Apr 1.

State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, China; National Engineering Laboratory for Industrial Wastewater Treatment, East China University of Science and Technology, Shanghai 200237, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address:

Flow-through electrodes generally outcompete traditional parallel-plate electrodes in current efficiency and mass transfer. High-performance electrode materials can be costly and complicated to fabricate, hindering their wide application. In this study, we used commercial graphite felt (GF) as the cathode of a flow-through electrochemical cell to investigate its potential in treating Cr(VI) solution through electroreduction. Read More

View Article and Full-Text PDF

Exploration of E. coli contamination drivers in private drinking water wells: An application of machine learning to a large, multivariable, geo-spatio-temporal dataset.

Water Res 2021 Mar 27;197:117089. Epub 2021 Mar 27.

Department of Civil Engineering, McMaster University, 1280 Main St. W, Hamilton, Ontario, L8S 4L8, Canada; Department of Geography and Planning and Global Institute for Water Security, University of Saskatchewan, 117 Science Place, Saskatoon, Saskatchewan, S7N 5C8, Canada.

Groundwater resources are under increasing threats from contamination and overuse, posing direct threats to human and environmental health. The purpose of this study is to better understand drivers of, and relationships between, well and aquifer characteristics, sampling frequencies, and microbiological contamination indicators (specifically E. coli) as a precursor for improving knowledge and tools to assess aquifer vulnerability and well contamination within Ontario, Canada. Read More

View Article and Full-Text PDF

Real-world analysis of clinical and economic impact of 21-gene recurrence score (RS) testing in early-stage breast cancer (ESBC) in Ireland.

Breast Cancer Res Treat 2021 Apr 9. Epub 2021 Apr 9.

Department of Medical Oncology, St Vincent's University Hospital, Dublin 4, Ireland.

Purpose: Results from TAILOR-X suggest that up to 70% of hormone receptor-positive (HR+) node-negative (N0) ESBC patients (pts) may avoid chemotherapy (CT) with RS ≤ 25. We assess clinical and economic impacts of RS testing on treatment using real-world data.

Methods: From October 2011 to February 2019, a retrospective, cross-sectional observational study was conducted of HR+ N0 ESBC pts who had RS testing in Ireland. Read More

View Article and Full-Text PDF

Epigenetics: A Missing Link Between Early Life Stress and Depression.

Adv Exp Med Biol 2021 ;1305:117-128

Center of Molecular Biology & Pharmacogenetics, Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Temuco, Chile.

Exposure to early life stress (ELS) represents a major risk factor for the development of psychiatric disorders, including depression. The susceptibility associated with ELS may result from persistent changes in gene transcription, which can occur through epigenetic mechanisms, such as DNA methylation, histone modifications, and microRNA expression. Animal models and reports in humans described that negative stimuli can alter the neurodevelopment of an individual, affecting their behavior and cognitive development. Read More

View Article and Full-Text PDF

Mortality rates and risk factors after low-trauma hip fracture in the largest university center in Romania.

Arch Osteoporos 2021 Apr 8;16(1):64. Epub 2021 Apr 8.

Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, 34-38 Aviatorilor blvd, 011863, Bucharest, Romania.

We calculated in-hospital, 30-day, and 1-year mortality rates and analyzed potential mortality risk factors in 2742 patients with low-trauma hip fractures. We found a high mortality rate at 30 days and 1 year after hip fracture. The high mortality can be explained by a very high number of conservatively treated fractures. Read More

View Article and Full-Text PDF

A community-supported metaproteomic pipeline for improving peptide identifications in hydrothermal vent microbiota.

Brief Bioinform 2021 Apr 8. Epub 2021 Apr 8.

School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Microorganisms in deep-sea hydrothermal vents provide valuable insights into life under extreme conditions. Mass spectrometry-based proteomics has been widely used to identify protein expression and function. However, the metaproteomic studies in deep-sea microbiota have been constrained largely by the low identification rates of protein or peptide. Read More

View Article and Full-Text PDF

The prevalence and impact of maltreatment of child laborers in the context of four South Asian countries: A scoping review.

Child Abuse Negl 2021 Apr 5;117:105052. Epub 2021 Apr 5.

College of Nursing and Health Sciences, Flinders University, SA, 5042, Australia. Electronic address:

Background: Child maltreatment is a global health concern, which adversely affects millions of children. Among them, child laborers are highly susceptible to maltreatment due to their economic vulnerability and workplace practices.

Objectives: This review seeks to identify the extent, risk factors and psychological impairments associated with the maltreatment of child laborers in four South East Asian countries. Read More

View Article and Full-Text PDF

Pre-micro RNA polymorphism detection in small versus large vessel disease in stroke Egyptian patients.

Metab Brain Dis 2021 Apr 8. Epub 2021 Apr 8.

Neurology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Stroke is the main cause of adult disability and is responsible for around 11% of deaths all over the world. Ischemic stroke encompasses about 80-85% of total stroke cases. Several studies have shown the relation between microRNAs polymorphism and ischemic stroke. Read More

View Article and Full-Text PDF

Impact of renin-angiotensin system inhibitors and beta-blockers on dental implant stability.

Int J Implant Dent 2021 Apr 8;7(1):31. Epub 2021 Apr 8.

Prof. Dr. Dr. Stoll & Partner Wilhelmstraße 3, 79098, Freiburg, Germany.

Background: Current experimental research suggests antihypertensive medication reduces the failure risk of dental implants due to enhanced bone remodeling. However, evidence from clinical studies evaluating the impact of antihypertensive medication on implant stability is lacking.

Methods: We retrospectively analyzed 377 implants in 196 patients (46 implants inserted in antihypertensive drug users (AH) and 331 implants in non-users (NAH)) for implant stability measured by radiofrequency analysis, and we determined the implant stability quotient (ISQ). Read More

View Article and Full-Text PDF

Atherosclerotic cardiovascular disease events among statin eligible individuals with and without long-term healthy arterial aging.

Atherosclerosis 2021 Mar 26. Epub 2021 Mar 26.

The Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address:

Background And Aims: A large proportion of statin eligible candidates have a baseline absence of coronary artery calcium (CAC) and low 10-year atherosclerotic cardiovascular disease (ASCVD) risk. We sought to determine the proportion of statin eligible individuals who had long-term healthy arterial aging (persistent CAC = 0) and their examined 15-year ASCVD outcomes.

Methods: We included 561 statin eligible candidates from the Multi-Ethnic Study of Atherosclerosis who were not on statin therapy with CAC = 0 at Visit 1 (2000-02) and underwent a subsequent CAC scan at Visit 5 (2010-11). Read More

View Article and Full-Text PDF

Clinical Characteristics and Controllable Risk Factors of Osteoporosis in Elderly Men with Diabetes Mellitus.

Orthop Surg 2021 Apr 5. Epub 2021 Apr 5.

State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia; Department of Endocrinology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Objective: To analyze the clinical characteristics and controllable risk factors of osteoporosis in elderly men with type-2 diabetes mellitus (T2DM).

Methods: A total of 250 elderly OP patients with T2DM were included in the present study. Patients with one or more common chronic diseases (including hypertension, coronary heart disease, heart failure, chronic bronchitis, chronic nephrosis, and cirrhosis), and a course of more than 3 years were defined as complicated with chronic diseases. Read More

View Article and Full-Text PDF

Child labor in Tehran, Iran: Abuses experienced in work environments.

Child Abuse Negl 2021 Apr 2;117:105054. Epub 2021 Apr 2.

West Texas A&M University, Harrington Amarillo Center 380C, Amarillo, TX, USA.

Background: Child labor is exploitative and harmful and deprives children of opportunities for a healthy life. Nonetheless, child labor is prevalent worldwide. Abusive working conditions are common, especially in developing countries. Read More

View Article and Full-Text PDF

Respiratory outcomes in the first ten years-of-life in children with gastroschisis: a retrospective cohort study.

Pediatr Pulmonol 2021 Apr 5. Epub 2021 Apr 5.

Department of Surgery, Division of Pediatric Surgery, University of Manitoba and Children's Hospital Research Institute of Manitoba.

Background: Little attention has been given to the long-term respiratory outcomes of children with gastroschisis. The purpose of this study was to determine if gastroschisis survivors have more respiratory illnesses in their first 10 years-of-life compared to age-matched controls.

Methods: We performed a retrospective cohort study of all gastroschisis children born in Manitoba between 1991-2017. Read More

View Article and Full-Text PDF

The Association of β2-Microglobulin and Fibroblast Growth Factor 23 with Major Adverse Cardiac Event in Acute Coronary Syndrome Patients with Chronic Kidney Disease.

Acta Med Indones 2021 Jan;53(1):5-12

Division of Cardiology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Background: chronic kidney disease (CKD) increases the severity and risk of mortality in acute coronary syndrome (ACS) patients. The role of β2-M as a filtration and inflammation marker and FGF23 as a CKD-MBD process marker might be significant in the pathophysiology in ACS with CKD patients. This study aims to determine the association of β2-M and FGF23 with major adverse cardiac event (MACE) in ACS patients with CKD. Read More

View Article and Full-Text PDF
January 2021

Prospective evaluation of the first-trimester screening strategy for preterm pre-eclampsia and its clinical applicability in China.

Ultrasound Obstet Gynecol 2021 Apr 5. Epub 2021 Apr 5.

Department of Obstetrics and Gynecology, Beijing Shunyi District Maternal and Child Health Hospital, Beijing, China.

Objectives: To evaluate the performance of screening strategy for preterm preeclampsia using the Fetal Medicine Foundation (FMF)'s competing risk model in mainland China and to explore its clinical applicability.

Methods: A prospective multicenter study was conducted and 10,899 singleton pregnancies were included, Mean arterial pressure (MAP), uterine artery pulsatility index (UtPI), maternal serum levels of placental growth factor (PlGF) and pregnancy associated plasma protein A (PAPPA) at 11-13 weeks' gestation were measured and converted into multiples of median according to localized parameters, individualized risk stratification was calculated using FMF's algorithm. Prior risk was calculated based on maternal characteristics and obstetric history information. Read More

View Article and Full-Text PDF