118 results match your criteria rhizome paris


Study on the identification and evaluation of growth years for Paris polyphylla var. yunnanensis using deep learning combined with 2DCOS.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Nov 30;261:120033. Epub 2021 May 30.

Medicinal Plants Research Institute, Yunnan Academy of Agricultural Sciences, Kunming 650200, China. Electronic address:

Paris polyphylla var. yunnanensis, as perennial plants, its quality is closely related to growth period. Different harvest years determine the dry matter accumulation of its medicinal parts and the dynamic accumulation of active ingredients, as well as its economic value and medicinal value. Read More

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November 2021

The traditional uses, phytochemistry, and pharmacological properties of Paris L. (Liliaceae): A review.

J Ethnopharmacol 2021 Oct 5;278:114293. Epub 2021 Jun 5.

Medicinal Plants Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, China. Electronic address:

Ethnopharmacological Relevance: Paris L. (Liliaceae) consisted of 33 species, of which the study focused on Paris polyphylla Smith, P. polyphylla var. Read More

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October 2021

Molecular-networking-guided discovery of species-specific markers for discriminating five medicinal Paris herbs.

Phytomedicine 2021 May 10;85:153542. Epub 2021 Mar 10.

State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China. Electronic address:

Background: Paridis Rhizoma (PR) is a famous traditional herbal medicine. Apart from two officially recorded species, viz. Paris polyphylla Smith var. Read More

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[Screening and identification of potassium-dissolving bacteria from different rhizosphere soil of Paris polyphylla var. yunnanensis].

Zhongguo Zhong Yao Za Zhi 2021 Mar;46(5):1073-1078

College of Biological and Food Engineering,Chongqing Three Gorges University Chongqing 404120,China Chongqing Engineering Laboratory for Green Cultivation and Deep Processing of the Three Gorges Reservoir Area's Medicinal Herbs Chongqing 404120,China.

The study aiming at exploring the potassium-dissolving capacity of rhizosphere potassium-dissolving bacteria from diffe-rent sources and screen the strains with high potassium-dissolving ability, so as to lay a theoretical foundation for cultivation and quality improvement of Paris polyphylla var. yunnanensis sources. The rhizosphere soil of 10 wild and transplanted species from Yunnan, Sichuan and Guizhou provinces was used as the research object. Read More

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Influence of drying process on furostanoside and spirostanoside profiles of Paridis Rhizoma by combination of HPLC, UPLC and UPLC-QTOF-MS/MS analyses.

J Pharm Biomed Anal 2021 Apr 1;197:113932. Epub 2021 Feb 1.

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address:

Drying method is one of the important factors affecting quality of traditional Chinese medicine. To study the effect of shaded drying and hot air drying on steroidal saponins of Paridis Rhizoma (PR), high performance liquid chromatography (HPLC) analysis was used to investigate the difference of Paris polyphylla var. chinensis (PPC) samples treated by different methods, and then, a rapid and reliable ultra-high performance liquid chromatography (UPLC) method was established to quantitatively analyze the content change of ten steroidal saponins. Read More

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saponin H inhibits the proliferation of glioma cells through the A1 and A3 adenosine receptor‑mediated pathway.

Int J Mol Med 2021 04 4;47(4). Epub 2021 Feb 4.

Department of Chinese Materia Medica and Natural Medicines, Air Force Medical University, Xi'an, Shaanxi 710032, P.R. China.

saponin H (PSH) is a type of steroid saponin derived from Rhizoma Paridis (RP; the rhizome of ). In our previous studies, saponins from RP exerted antiglioma activity . However, the effects of PSH on glioma have not been elucidated. Read More

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Evaluation of antioxidant, anti-inflammatory and anticancer activities of diosgenin enriched Paris polyphylla rhizome extract of Indian Himalayan landraces.

J Ethnopharmacol 2021 Apr 16;270:113842. Epub 2021 Jan 16.

Department of Biotechnology, National Institute of Technology (NIT)-Arunachal Pradesh, Yupia, 791112, Papum Pare, Arunachal Pradesh, India. Electronic address:

Ethnopharmacological Relevance: Traditional medicinal plants have gained attention as a potential therapeutic agent to combat cancer and inflammation. Diosgenin rich fresh extracts of Paris polyphylla rhizome from Indian Himalaya is traditionally used as wound healing, anti-bleeding, anti-inflammatory and anti-cancer agent by the folk healers.

Aim Of The Study: Present study was aimed to prepare two types of extracts from Paris polyphylla rhizome of Indian Himalayan landraces - 1. Read More

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A new homo-aro-cholestane glycoside from the rhizome of var. .

J Asian Nat Prod Res 2020 Nov 23:1-8. Epub 2020 Nov 23.

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

A new homo-aro-cholestane glycoside parispolyside H, along with nine known compounds, were isolated from 75% ethanolic extract of the rhizome of var. . Their chemical structures were elucidated on the basic of analysis of detailed spectroscopic and physicochemical properties. Read More

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November 2020

Communities of mycorrhizal fungi in different trophic types of Asiatic Pyrola japonica sensu lato (Ericaceae).

J Plant Res 2020 Nov 24;133(6):841-853. Epub 2020 Oct 24.

Agro-Environmental Science, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.

Mixotrophic plants obtain carbon by their own photosynthetic activity and from their root-associated mycorrhizal fungi. Mixotrophy is deemed a pre-adaptation for evolution of mycoheterotrophic nutrition, where plants fully depend on fungi and lose their photosynthetic activity. The aim of this study was to clarify mycorrhizal dependency and heterotrophy level in various phenotypes of mixotrophic Pyrola japonica (Ericaceae), encompassing green individuals, rare achlorophyllous variants (albinos) and a form with minute leaves, P. Read More

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November 2020

Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications.

Front Pharmacol 2020 15;11:01021. Epub 2020 Sep 15.

Faculty of Medicine, University of Porto, Porto, Portugal.

Curcumin, a yellow polyphenolic pigment from the L. (turmeric) rhizome, has been used for centuries for culinary and food coloring purposes, and as an ingredient for various medicinal preparations, widely used in Ayurveda and Chinese medicine. In recent decades, their biological activities have been extensively studied. Read More

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September 2020

Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves.

Phytochemistry 2020 Oct 21;178:112460. Epub 2020 Jul 21.

CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China; Center of Economic Botany, Core Botanical Gardens, Chinese Academy of Sciences, Menglun, Mengla, Yunnan, 666303, China; The Innovative Academy of Seed Design, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China. Electronic address:

Paris polyphylla var. yunnanensis can synthesize Paris saponins with multiple effective therapies, and its rhizome has become an indispensable ingredient in many patented drugs. However, how Paris saponin content changes in tissues at different stages and the molecular mechanisms underlying the production and accumulation of the bioactive compounds are unclear. Read More

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October 2020

[Determination of five steroidal saponins in Paridis Rhizoma and its adulterants as well as consideration on its quantitative method described in Chinese Pharmacopoeia (2015 edition)].

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(8):1745-1755

National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

Paridis Rhizoma is prepared from the dried rhizoma of Paris polyphylla var. yunnanensis or P. polyphylla var. Read More

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Molecular networking uncovers steroidal saponins of Paris tengchongensis.

Fitoterapia 2020 Sep 16;145:104629. Epub 2020 May 16.

State Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address:

Based on a method combining the LC-MS/MS molecular networking strategy with the conventional means of phytochemical research, the chemical constituents and the availability of Paris tengchongensis, a new species found in 2017 from Yunnan Province, were investigated for the first time. The molecular networking showed that this species contained the characteristic steroidal glycosides of the genus Paris by comparison of those of Paris polyphylla var. yunnanensis. Read More

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September 2020

A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.

Biosci Trends 2020 May 14;14(2):123-133. Epub 2020 Mar 14.

Institute of Materia Medica, School of Pharmacy, Fourth Military Medical University, Xi'an, China.

Glioblastoma is one of the most difficult cancers to treat with a 5-year overall survival rate less than 5%. Temozolomide (TMZ) is an effective drug for prolonging the overall survival time of patients, while drug-resistance is an important clinical problem at present. Pennogenin-3-α-L-rhamnopyranosyl-(1→4)-[α-Lrhamno-pyranosyl-(1→2)]- β-D-glucopyranoside (N45), a steroidal saponin, was isolated from the rhizomes of Paris vietnamensis (Takht. Read More

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Niche differentiation in the rhizosphere and endosphere fungal microbiome of wild Sm.

PeerJ 2020 5;8:e8510. Epub 2020 Feb 5.

College of Life Sciences, Shaanxi Normal University, Xi'an, China.

Background: The plant microbiome is one of the key determinants of plant health and metabolite production. The plant microbiome affects the plant's absorption of nutrient elements, improves plant tolerance to negative environmental factors, increases the accumulation of active components, and alters tissue texture. The microbial community is also important for the accumulation of secondary metabolites by plants. Read More

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February 2020

Anti-cancer effects of Polyphyllin I: An update in 5 years.

Chem Biol Interact 2020 Jan 20;316:108936. Epub 2019 Dec 20.

Department of Hematology, Affiliated Zhongshan Hospital of Dalian University, Dalian, 116001, China. Electronic address:

Chong-lou, the rhizome of Paris polyphylla, has been used in herbal regimes to treat parotitis, mastitis and certain malignant tumors for thousands of years in traditional medicine. Polyphyllin I (PPI) is the main bioactive component in Paris polyphylla. Recent studies of PPI in various types of cancers have shown that PPI may exert a broad spectrum of anti-tumor effects, including inducing cell cycle arrest, inducing cell apoptosis, inducing autophagy, anti-angiogenesis, sensitizing tumors to chemotherapy, and participating in the modulation of inflammatory and immune response. Read More

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January 2020

Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation.

Cell Death Discov 2019 9;5:150. Epub 2019 Dec 9.

1CNRS UMR 8003, SSPIN Saints-Pères Neurosciences Institute, Paris University, Saint-Germain Campus, 45 rue des Saints-Pères, 75006 Paris, France.

Iron overload, notably caused by hereditary hemochromatosis, is an excess storage of iron in various organs that causes tissue damage and may promote tumorigenesis. To manage that disorder, free iron depletion can be induced by iron chelators like deferoxamine that are of increasing interest also in the cancer field since iron stock could be a potent target for managing tumorigenesis. Curcumin, a well-known active substance extracted from the turmeric rhizome, destabilizes endoplasmic reticulum, and secondarily lysosomes, thereby increasing mitophagy/autophagy and subsequent apoptosis. Read More

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December 2019

Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide.

Oxid Med Cell Longev 2019 14;2019:1805635. Epub 2019 Nov 14.

Laboratory of Experimental Animal Disease Model, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

The high recurrence frequency of gliomas but deficiency of effective treatment and prevalent chemoresistance have elicited interests in exploring and developing new agents. Paris polyphyllins are monomers extracted from rhizome of Paris polyphylla var. yunnanensis. Read More

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Capturing the Geoherbalism Differentiation in Wild var. Raw Materials through the Application of Multispectral Information Fusion Combined with Chemometrics.

ACS Omega 2019 Nov 1;4(20):18820-18832. Epub 2019 Nov 1.

Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650200, China.

var. is a famous medicinal plant distributed in some Asian countries. This species has attracted a great deal of attention and is often used as raw materials in traditional medicine practices. Read More

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November 2019

Isolation of Yasminevirus, the First Member of Klosneuvirinae Isolated in Coculture with Vermamoeba vermiformis, Demonstrates an Extended Arsenal of Translational Apparatus Components.

J Virol 2019 12 12;94(1). Epub 2019 Dec 12.

Aix-Marseille Université, MEPHI (Microbes, Evolution, Phylogeny and Infections), IRD, APHM, Faculté de Médecine, Marseille, France

The family of giant viruses is still expanding, and evidence of a translational machinery is emerging in the virosphere. The Klosneuvirinae group of giant viruses was first reconstructed from studies, and then a unique member was isolated, Bodo saltans virus. Here we describe the isolation of a new member in this group using coculture with the free-living amoeba This giant virus, called Yasminevirus, has a 2. Read More

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December 2019

Polyphyllin I induces autophagy and cell cycle arrest via inhibiting PDK1/Akt/mTOR signal and downregulating cyclin B1 in human gastric carcinoma HGC-27 cells.

Biomed Pharmacother 2019 Sep 4;117:109189. Epub 2019 Jul 4.

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, National Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu 611137, China. Electronic address:

Paris polyphylla. is a traditional medicinal herb that has long been used to prevent cancer in many Asian countries. Polyphyllin I (PPI), an important bioactive constituent of Paris polyphylla, has been found to exhibit a wide variety of anticancer activities in many types of cancer cells. Read More

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September 2019

Determination of Inorganic Elements in the Rhizome of Smith Var. (Franch.) Hara by Using Inductively Coupled Plasma Mass Spectrometry.

J Anal Methods Chem 2019 9;2019:4946192. Epub 2019 Jun 9.

West China School of Pharmacy, Sichuan University, Chengdu 610041, China.

The objective of this study was to investigate the concentrations of inorganic elements in the rhizome of Smith var. (Franch.) Hara of different planting years and cultivation conditions. Read More

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Chloroplast phylogenomic analysis provides insights into the evolution of the largest eukaryotic genome holder, Paris japonica (Melanthiaceae).

BMC Plant Biol 2019 Jul 4;19(1):293. Epub 2019 Jul 4.

Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, People's Republic of China.

Background: Robust phylogenies for species with giant genomes and closely related taxa can build evolutionary frameworks for investigating the origin and evolution of these genomic gigantisms. Paris japonica (Melanthiaceae) has the largest genome that has been confirmed in eukaryotes to date; however, its phylogenetic position remains unresolved. As a result, the evolutionary history of the genomic gigantisms in P. Read More

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Comparative analysis of proteomic and metabolomic profiles of different species of Paris.

J Proteomics 2019 05 16;200:11-27. Epub 2019 Mar 16.

National Center of Biomedical Analysis, Beijing 100850, China.

An extract prepared from species of Paris is the most widely consumed herbal product in China. The genus Paris includes a variety of genotypes with different medicinal component contents but only two are defined as official sources. Closely related species have different medicinal properties because of differential expression of proteins and metabolites. Read More

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Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from , Is a New Inhibitor of Hepatitis C Virus RNA Replication.

J Virol 2019 05 1;93(10). Epub 2019 May 1.

Center for Infection and Immunity of Lille (CIIL), University of Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019, UMR 8204, Lille, France

Recent emergence of direct-acting antivirals (DAAs) targeting hepatitis C virus (HCV) proteins has considerably enhanced the success of antiviral therapy. However, the appearance of DAA-resistant-associated variants is a cause of treatment failure, and the high cost of DAAs renders the therapy not accessible in countries with inadequate medical infrastructures. Therefore, the search for new inhibitors with a lower cost of production should be pursued. Read More

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Traceability the provenience of cultivated Paris polyphylla Smith var. yunnanensis using ATR-FTIR spectroscopy combined with chemometrics.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Apr 3;212:132-145. Epub 2019 Jan 3.

Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650200, China. Electronic address:

The conventional procedures, based on attenuated total reflectance-Fourier transform infrared spectrometry (ATR-FTIR), have been developed for the origins traceability of cultivated Paris polyphylla Smith var. yunnanensis (PPY) samples with the help of partial least square discriminant analysis (PLS-DA) and random forest. In this study, a set of 219 batch cultivated PPY samples, containing the cultivation years of 5, 6 and 7, and covering the municipal districts of Chuxiong, Dali, Honghe, Lijiang and Yuxi in Yunnan Province, China, were used to build the discrimination models. Read More

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Comparison and Identification for Rhizomes and Leaves of Paris yunnanensis Based on Fourier Transform Mid-Infrared Spectroscopy Combined with Chemometrics.

Molecules 2018 Dec 17;23(12). Epub 2018 Dec 17.

Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650200, China.

, as a traditional herb with long history, has been widely used to treat diseases in multiple nationalities of China. Nevertheless, the quality of fluctuates among from different geographical origins, so that a fast and accurate classification method was necessary for establishment. In our study, the geographical origin identification of 462 rhizome and leaf samples from Kunming, Yuxi, Chuxiong, Dali, Lijiang, and Honghe were analyzed by Fourier transform mid infrared (FT-MIR) spectra, combined with partial least squares discriminant analysis (PLS-DA), random forest (RF), and hierarchical cluster analysis (HCA) methods. Read More

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December 2018

A plastid phylogeny of the fern genus Arachniodes (Dryopteridaceae).

Mol Phylogenet Evol 2019 04 11;133:214-235. Epub 2018 Dec 11.

CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, P.O. Box 416, Chengdu, Sichuan 610041, China; Missouri Botanical Garden, 4344 Shaw Blvd., St. Louis, MO 63110, USA. Electronic address:

Arachniodes (Dryopteridaceae) is one of the most confusing and controversial fern genera in terms of its circumscription, nomenclature, and taxonomy. Estimates of species number range from 40 to 200. Previous molecular works included only 2-17 accessions representing 2-12 species of Arachniodes and allied genera, leaving most of the Asian species remain unsampled and the infragneric relationships unclear. Read More

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Mixotrophic orchids do not use photosynthates for perennial underground organs.

New Phytol 2019 01 16;221(1):12-17. Epub 2018 Sep 16.

Institut de Systématique, Evolution, Biodiversité (ISYEB), Muséum national d'Histoire naturelle, CNRS, Sorbonne Université, EPHE, CP 39, 57 rue Cuvier, 75005, Paris, France.

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January 2019

Seeing the light: Shifting from wild rhizomes to extraction of active ingredients from above-ground parts of Paris polyphylla var. yunnanensis.

J Ethnopharmacol 2018 Oct 21;224:134-139. Epub 2018 May 21.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People's Republic of China. Electronic address:

Ethnopharmacological Relevance: The dried rhizomes of Paris polyphylla var. yunnanensis are widely used in traditional Chinese medicine (TCM) as hemostatic, antitumor, and antimicrobial agents. More than 70 Chinese patent medicines are based on P. Read More

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October 2018