134,841 results match your criteria reviewed incidence

Neonatal Withdrawal Syndrome following Late in utero Exposure to Selective Serotonin Reuptake Inhibitors: A Systematic Review and Meta-Analysis of Observational Studies.

Psychother Psychosom 2021 May 10:1-9. Epub 2021 May 10.

Department of Health Sciences, University of Florence, Florence, Italy.

Introduction: A clear picture of neonatal withdrawal signs due to in utero selective serotonin reuptake inhibitor (SSRI) exposure and its consequences is still missing.

Objective: A systematic review and a meta-analysis were performed to provide an overview of neonatal withdrawal signs following late in utero exposure to SSRIs and to quantify the corresponding risks.

Methods: MEDLINE, Web of Science, and Embase were searched from inception to January 2021. Read More

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Pituicytoma: Report of three cases and a systematic literature review.

Clin Neurol Neurosurg 2021 Apr 24;205:106650. Epub 2021 Apr 24.

Department of Neurosurgery, Beijing Tiantan hospital, Capital Medical University, 119 South Fourth Ring West Road, Fengtai District, Beijing 100070, China. Electronic address:

Pituicytoma is a rare subtype of WHO grade I glioma that originates in the neurohypophysis or infundibulum. Here we presented 3 cases of histopathologically diagnosed pituicytoma and subsequently performed a corresponding systematic literature review. A comprehensive literature search of the PubMed database was conducted. Read More

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Not so sweet and simple: impacts of SARS-CoV-2 on the β cell.

Islets 2021 May 10:1-14. Epub 2021 May 10.

Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, USA.

The link between COVID-19 infection and diabetes has been explored in several studies since the start of the pandemic, with associations between comorbid diabetes and poorer prognosis in patients infected with the virus and reports of diabetic ketoacidosis occurring with COVID-19 infection. As such, significant interest has been generated surrounding mechanisms by which the virus may exert effects on the pancreatic β cells. In this review, we consider possible routes by which SARS-CoV-2 may impact β cells. Read More

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Incidence and risk factors for symptomatic venous thromboembolism following anterior cruciate ligament reconstruction.

Knee Surg Sports Traumatol Arthrosc 2021 May 10. Epub 2021 May 10.

Rush University Medical Center, 1611 W Harrison St, Chicago, IL, 60612, USA.

Purpose: To determine the incidence of symptomatic venous thromboembolism (VTE) following anterior cruciate ligament (ACL) reconstruction using a large national database and to identify corresponding independent risk factors.

Methods: The Humana administrative claims database was reviewed for patients undergoing ACL reconstruction from 2007 to 2017. Patient demographics, medical comorbidities, as well as concurrent procedures were recorded. Read More

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Immune Checkpoint Inhibitor Associated Hepatotoxicity in Primary Liver Cancer Versus Other Cancers: A Systematic Review and Meta-Analysis.

Front Oncol 2021 21;11:650292. Epub 2021 Apr 21.

Thoracic and Gastrointestinal Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

Background: Overall risks of hepatotoxicity with immune checkpoint inhibitors (ICIs) have yet to be compared in primary liver cancers to other solid tumors.

Methods: We reviewed data from the PubMed, Embase, and Scopus databases, and assessed the risk of hepatotoxicity associated with ICIs.

Results: A total of 117 trials were eligible for the meta-analysis, including 7 trials with primary liver cancers. Read More

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Dabigatran, rivaroxaban, and apixaban are superior to warfarin in Asian patients with non-valvular atrial fibrillation: An updated meta-analysis.

World J Cardiol 2021 Apr;13(4):82-94

Department of Medicine, Jacobi Medical Center, Bronx, NY 10461, United States.

Background: Most of the randomized clinical trials that led to the wide use of non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation (AF) originated from western countries.

Aim: To systematically review and quantitatively synthesize the real-world data regarding the efficacy and safety of dabigatran, rivaroxaban, and apixaban compared to warfarin for stroke prevention in Asian patients with non-valvular AF.

Methods: Medline, Cochrane, and ClinicalTrial. Read More

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Introducing V-Line as a New Strategy to Choose Surgical Corridor in Oblique Lumbar Interbody Fusion at the L5-S1 Segment.

Dis Markers 2021 22;2021:5584372. Epub 2021 Apr 22.

Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, YouYi Road 1#, YuZhong District, Chongqing 400016, China.

Purpose: A retrospective imaging study assessing the availability of oblique lumbar interbody fusion at the level of L5-S1 (OLIF51) and to choose ideal surgical corridor in OLIF51 by introducing V-line.

Methods: The axial views through the center of L5-S1 disc were reviewed. We adopt 18 mm as the width of the simulated surgical corridor. Read More

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Nuclear Imaging for Cardiac Amyloidosis: Bone Scan, SPECT/CT, and Amyloid-Targeting PET.

Nucl Med Mol Imaging 2021 Apr 7;55(2):61-70. Epub 2021 Jan 7.

Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, 06351 Seoul, Republic of Korea.

Cardiac amyloidosis (CA) is a type of systemic amyloidosis, in which abnormal amyloid fibril is deposited in extracellular space of myocardium. Most common subtypes of CA are amyloidosis of immunoglobulin light chain (AL) and amyloidosis of transthyretin (ATTR). With increase in incidence of CA and development of new drugs, the needs of early and accurate diagnosis of CA are increasing. Read More

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Level I Nodal Positivity as a Factor for Involvement of the Submandibular Gland in Oral Cavity Carcinoma: A Case Series Report.

Int Arch Otorhinolaryngol 2021 Apr 30;25(2):e279-e283. Epub 2020 Jun 30.

Department of Surgery, Aga Khan University, Karachi, Pakistan.

 The routine practice of neck dissection in the surgical management of oral carcinoma has evolved into a more functionally conservative approach. Over time, the rationale for removal of the submandibular gland has been questioned. Routine extirpation of the submandibular gland can aggravate the xerostomia experienced by many patients, significantly affecting their quality of life. Read More

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The Incidence of Stroke in Indigenous Populations of Countries With a Very High Human Development Index: A Systematic Review Protocol.

Front Neurol 2021 22;12:661570. Epub 2021 Apr 22.

School of Population and Global Health, University of Western Australia, Perth, WA, Australia.

Despite known Indigenous health and socioeconomic disadvantage in countries with a Very High Human Development Index, data on the incidence of stroke in these populations are sparse. With oversight from an Indigenous Advisory Board, we will undertake a systematic review of the incidence of stroke in Indigenous populations of developed countries or regions, with comparisons between Indigenous and non-Indigenous populations of the same region, though not between different Indigenous populations. Using PubMed, OVID-EMBASE, and Global Health databases, we will examine population-based incidence studies of stroke in Indigenous adult populations of developed countries published 1990-current, without language restriction. Read More

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Effectiveness of Trainings of General Practitioners on Antibiotic Stewardship: Methods of a Pragmatic Quasi-Experimental Study in a Controlled Before-After Design in South-East-Lower Saxony, Germany (WASA).

Front Pharmacol 2021 22;12:533248. Epub 2021 Apr 22.

Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

Antibiotic resistance is a serious threat to global public health. It reduces the effectiveness of treatments for serious bacterial infections and thus increases the risk of fatal outcomes. Antibiotic prescriptions are often not in line with clinical evidence-based guidelines. Read More

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Correlative study of tumor budding, mode of invasion and lymphocytic host response with known clinicopathological prognostic factors in oral squamous cell carcinoma.

J Oral Maxillofac Pathol 2020 Sep-Dec;24(3):484-491. Epub 2021 Jan 9.

Department of Pathology, NRI Medical College, Chinakakani, Guntur, Andhra Pradesh, India.

Background: Oral squamous cell carcinoma (OSCC) is a significant public health problem in India, accounting to 30% of all cancers with a worrying rise in incidence and related mortality. Invasive tumor front (ITF) of OSCC has been an area of histopathologic research interest, where parameters like tumor budding (TB), mode of invasion (MOI) and lymphocytic host response (LHR) are being evaluated extensively.

Objectives: The aim is to study and evaluate the possible association of ITF histological parameters such as TB, LHR and MOI with known clinicopathological prognostic factors in cases of OSCC. Read More

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January 2021

Validation of cobas 4800 HPV assay in SurePath Papanicolaou specimens for cervical cancer screening.

J Am Soc Cytopathol 2021 Apr 19. Epub 2021 Apr 19.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Introduction: The cobas (Roche Diagnostics, Indianapolis, IN) HPV assay was approved by the US Food and Drug Administration for human papillomavirus (HPV) testing in SurePath (Becton Dickinson, Franklin Lakes, NJ) Papanicolaou specimens for cervical cancer prevention. To validate the cobas HPV assay in SurePath specimens in our institution, we compared its accuracy and clinical efficacy to that of the Cervista (Hologic, Marlborough, MA) HPV HR assay.

Methods: This study used 138 Papanicolaou (Pap) cytology specimens collected in SurePath preservative fluid at our institution in 2018. Read More

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Stroke and Neurointervention in the COVID-19 pandemic: A narrative review.

Expert Rev Med Devices 2021 May 8. Epub 2021 May 8.

Cooper Neurological Institute, Cooper University Hospital, Camden NJ 08103.

Introduction: In this review, we will summarize the impact of the COVID-19 pandemic on neurointerventional care for patients with cerebrovascular disease, with a particular emphasis on epidemiology, neurointerventional processes, and lessons learned from paradigm shifts in endovascular care.

Areas Covered: Peer-reviewed research is summarized regarding the complications of COVID-19 as related to the pandemic's impact on hospital admissions, imaging capabilities, treatment times, and outcomes of neurointerventional cases.

Expert Opinion: In the first wave of the COVID-19 pandemic, there was a global decline in neuroimaging, use of intravenous thrombolysis, thrombectomy, and coil embolization for ruptured intracranial aneurysms. Read More

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Reasons for hospitalization and factors of mortality in patients with Parkinson's disease in the Philippines.

Neurodegener Dis Manag 2021 May 10. Epub 2021 May 10.

Department of Neurosciences, College of Medicine & Philippine General Hospital, University of The Philippines Manila, Manila, Philippines.

We aimed to determine the reasons for hospitalizations and factors of mortality of Filipino Parkinson's disease (PD) patients in a tertiary hospital. We conducted a retrospective review of medical records of PD patients admitted to our institution between 2016 and 2018. Demographic and clinical data were analyzed. Read More

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Signal Detection in EUROmediCAT: Identification and Evaluation of Medication-Congenital Anomaly Associations and Use of VigiBase as a Complementary Source of Reference.

Drug Saf 2021 May 9. Epub 2021 May 9.

Population Health Research Institute, St George's, University of London, London, UK.

Introduction: Knowledge on the safety of medication use during pregnancy is often sparse. Pregnant women are generally excluded from clinical trials, and there is a dependence on post-marketing surveillance to identify teratogenic medications.

Aims: This study aimed to identify signals of potentially teratogenic medications using EUROmediCAT registry data on medication exposure in pregnancies with a congenital anomaly, and to investigate the use of VigiBase reports of adverse events of medications in the evaluation of these signals. Read More

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Pediatric Snakebites: Comparing Patients in Two Geographic Locations in the United States.

J Surg Res 2021 May 6;265:297-302. Epub 2021 May 6.

Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Surgery, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee. Electronic address:

Background: Management of children with snakebites may vary based on subjective criteria, geographic, and climatic factors. We reviewed the incidence and management of snakebite injuries in children at two tertiary referral centers in separate geographic and climatic location to assess differences in management and outcomes of these patients.

Methods: After institutional review board approval, a retrospective chart review was performed for patients ≤18 years with snakebite injuries at emergency departments (ED) of two American College of Surgeons verified trauma centers (2006-2013). Read More

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Nationwide Burden of Sudden Cardiac Death: A Study of 54,028 Deaths in Denmark.

Heart Rhythm 2021 May 6. Epub 2021 May 6.

Department of Cardiology, Rigshospitalet, Denmark;; Section of Forensic Pathology, Copenhagen University, Denmark.

Background: A large proportion of all deaths are sudden cardiac death (SCD). Reliable estimates of nationwide incidence of SCD, however, are missing.

Objective: To estimate SCD burden across all ages in Denmark and compare this with other common causes of death. Read More

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Our experience with the laparoscopic surgery of hiatal hernias

Orv Hetil 2021 05 9;162(19):754-759. Epub 2021 May 9.

1 Markusovszky Egyetemi Oktatókórház, Szombathely.

Összefoglaló. Bevezetés: A hiatus hernia egy anatómiai betegség; gyakoribb előfordulása idősebbeknél jelezheti, hogy a betegség idővel előrehalad, súlyosbodik. Elhanyagolt esetben szövődmények alakulhatnak ki, melyek növelhetik a perioperatív mortalitást. Read More

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Salvage stereotactic body radiotherapy (SBRT) for intraprostatic relapse after prostate cancer radiotherapy: An ESTRO ACROP Delphi consensus.

Cancer Treat Rev 2021 Apr 20;98:102206. Epub 2021 Apr 20.

Department of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Background And Purpose: Between 30% and 47% of patients treated with definitive radiotherapy (RT) for prostate cancer are at risk of intraprostatic recurrence during follow-up. Re-irradiation with stereotactic body RT (SBRT) is emerging as a feasible and safe therapeutic option. However, no consensus or guidelines exist on this topic. Read More

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Association between serum bilirubin levels and progression of albuminuria in Taiwanese with type 2 diabetes mellitus.

Biomed J 2021 May 5. Epub 2021 May 5.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Background: To investigate the association between serum bilirubin (BIL) levels and the progression of albuminuria in type 2 diabetic Taiwanese.

Methods: Longitudinal data from January 2001 to June 2015 were retrospectively reviewed from Chang Gung Memorial Hospital in Taiwan. A total of 2877 type 2 diabetic patients with normal total BIL levels were divided into 4 groups according to BIL, with the highest BIL in the fourth group. Read More

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Discordance in Appendicitis Grading and the Association with Outcomes: A Post-Hoc Analysis of an EAST Multicenter Study.

J Surg Res 2021 May 5;265:259-264. Epub 2021 May 5.

Division of Trauma and Surgical Critical Care, DeWitt Daughtry Family Department of Surgery, Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, Florida.

Background: The American Association for the Surgery of Trauma (AAST) appendicitis severity grading criteria use independent subscales for radiologists (Rad), surgeons (Surg), and pathologists (Path). We reviewed the EAST Multicenter Study of the Treatment of Appendicitis in America: Acute, Perforated, and Gangrenous (MUSTANG) database to determine rates of discordance and clinical consequences of inaccuracy.

Materials And Methods: A confusion matrix was constructed for pairs among Rad, Surg, and Path. Read More

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Klebsiella pneumoniae Harboring Carbapenemase Genes in Taiwan: Its Evolution over 20 Years, 1998-2019.

Int J Antimicrob Agents 2021 May 5:106354. Epub 2021 May 5.

Department of Intensive Care Medicine, Chi Mei Medical Center, Tainan, Tainan; Department of Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Klebsiella pneumoniae is an important pathogen causing various types of human infections in Taiwan. Carbapenemases have increasingly been reported in Enterobacterales in the past two decades. Carbapenemase-producing K. Read More

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Outcomes of Posterior Labral Repair with or without Concomitant High-Grade Glenohumeral Chondral Pathology: a retrospective cohort with minimum 2-year follow-up.

J Shoulder Elbow Surg 2021 May 5. Epub 2021 May 5.

Carolinas Medical Center, Atrium Musculoskeletal Institute, 1025 Morehead Medical Dr., Suite #300, Charlotte, NC, 28204, USA. Electronic address:

Background: The purpose of this study was to compare outcomes of patients who underwent posterior labral repair with and without concomitant glenohumeral chondral pathology.

Methods: A retrospective review was performed on patients ≥ 18 years of age who underwent primary posterior labral repair over 5 years. Charts were reviewed to determine the presence and location of high-grade (Outerbridge Grade III/IV) pathology. Read More

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Pre-incision Adjunctive Prophylaxis for Cesarean Sections: A Systematic Review and Meta-analysis.

Am J Obstet Gynecol 2021 May 5. Epub 2021 May 5.

ObGyn & Women's Health Institute, 9500 Euclid Avenue, Cleveland, Ohio 44195. Electronic address:

Objective: To systematically review the relative effectiveness of pre-incision cefazolin with or without adjunctive prophylaxis (macrolides or metronidazole), versus cefazolin alone, in decreasing the incidence of post-Cesarean surgical site infections.

Data Sources: We performed a systematic search of PubMed, Ovid EMBASE, Google Scholar, ClinicalTrials.gov and Cochrane Central Register of Controlled Trials from October 25 to November 25, 2020, to identify studies comparing cefazolin with adjunctive macrolides or metronidazole to cefazolin alone. Read More

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Statin therapy and the incidence of thromboembolism and vascular events following liver transplantation.

Liver Transpl 2021 May 8. Epub 2021 May 8.

Mayo Clinic Arizona, Phoenix, AZ, USA.

Statin therapy may reduce the risk of venous thromboembolism (VTE), which may impact solid organ transplant outcomes. We evaluated the incidence of VTE and other complications after liver transplantation stratified by hyperlipidemia status and statin use using a retrospective cohort study approach from a high-volume liver transplant center. We reviewed all primary orthotopic liver transplant (OLT) records from January 2014-December 2019 from our center. Read More

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Does Training in LI-RADS Version 2018 Improve Readers' Agreement with the Expert Consensus and Inter-reader Agreement in MRI Interpretation?

J Magn Reson Imaging 2021 May 8. Epub 2021 May 8.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: The Liver Imaging Reporting and Data System (LI-RADS) was established for noninvasive diagnosis for hepatocellular carcinoma (HCC). However, whether training can improve readers' agreement with the expert consensus and inter-reader agreement for final categories is still unclear.

Purpose: To explore training effectiveness on readers' agreement with the expert consensus and inter-reader agreement. Read More

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Using Pressure Mapping to Optimize Hospital-Acquired Pressure Injury Prevention Strategies in the Burn Intensive Care Unit.

J Burn Care Res 2021 May 8. Epub 2021 May 8.

Department of Plastic & Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Although prior studies have demonstrated the utility of real-time pressure mapping devices in preventing pressure ulcers, there has been little investigation of their efficacy in burn intensive care unit (BICU) patients, who are at especially high risk for these hospital-acquired injuries. This study retrospectively reviewed clinical records of BICU patients to investigate the utility of pressure mapping data in determining the incidence, predictors and associated costs of hospital-acquired pressure injuries. Of 122 patients, 57 (47%) were studied prior to implementation of pressure mapping and 65 (53%) were studied after implementation. Read More

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Post-COVID syndrome: Incidence, clinical spectrum, and challenges for primary healthcare professionals.

Arch Med Res 2021 May 4. Epub 2021 May 4.

Directorate of Research, Studies and Documentation, National Public Health Organization, Athens, Greece. Electronic address:

Post-COVID syndrome also known as long COVID refers to symptoms persisting for more than three weeks after the diagnosis of COVID-19. We reviewed the current evidence on post-COVID syndrome, focusing on its clinical manifestations and addressing the challenges for its management in primary healthcare. The incidence of post-COVID syndrome is estimated at 10-35%, while for hospitalized patients it may reach 85%. Read More

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Multiple myeloma and physical activity.

BMC Res Notes 2021 May 7;14(1):171. Epub 2021 May 7.

University College London Behavioural Science and Health, Institute of Epidemiology & Health, 1-19 Torrington Place, London, WC1E 6BT, UK.

Objective: Physical activity has been shown to improve quality of life in cancer patients with some evidence in multiple myeloma. This study aimed to determine myeloma patients' exercise levels, their perception of physical activity, and to explore correlations with quality of life. Myeloma outpatients were invited to complete a number of questionnaires, including the Godin leisure-time exercise questionnaire (GLTEQ) to determine their exercise levels, the Functional Assessment of Cancer Therapy-General (FACT-G) questionnaire to assess health related quality of life, and the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) questionnaire to assess fatigue. Read More

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