18,213 results match your criteria reviewed eyes


Ocular symptoms as the initial clinical manifestations in patients with extraocular tumors.

Ann Transl Med 2021 Mar;9(6):497

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, China.

Background: Due to the variety of clinical presentation, some tumors may be concealed and easily misdiagnosed, leading to delays in management. We report a series of patients who initially presented to an Ophthalmic Clinic with ocular symptoms and were subsequently diagnosed with extraocular tumors.

Methods: Patients who presented to the ophthalmic outpatient clinic at the Joint Shantou International Eye Center with ocular symptoms between April 2013 and December 2019 and were subsequently diagnosed with intracranial or systemic tumors were reviewed retrospectively. Read More

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Preoperative imaging optimized for epiretinal membrane surgery.

Int J Retina Vitreous 2021 Apr 13;7(1):32. Epub 2021 Apr 13.

Ophthalmology Department, AP-HP, Hôpital Lariboisière, Université de Paris, 75010, Paris, France.

Background: To compare imaging modalities for visualizing primary epiretinal membrane (ERM) with each other and with intraoperative digital images (IDI) after blue staining.

Methods: The records of consecutive patients operated for primary ERM over a 12-month period were retrospectively reviewed. Preoperative imaging included color fundus photography (CFP), En Face spectral-domain optical coherence tomography (OCT), 45° infrared- (IR) and blue-reflectance (BR) scanning laser ophthalmoscopy. Read More

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Fall-related eye injury among older adults in the United States.

Am J Ophthalmol 2021 Apr 10. Epub 2021 Apr 10.

Department of Ophthalmology, Massachusetts Eye and Ear, 243 Charles St, Boston, MA 02114; Glaucoma Service, Massachusetts Eye and Ear, 243 Charles ST, Boston, MA 02114. Electronic address:

Purpose: To identify common causes of emergency department-treated eye injury among older adults in the United States (US), and to characterize of fall-related ocular trauma in this population.

Design: Retrospective cohort study METHODS: Data from the National Electronic Injury Surveillance System, a nationally representative database of US emergency department-treated injuries, was used to assemble a cohort of adults 65 years and older with eye injuries between January 1, 2000 and December 31, 2019. Demographic information, diagnosis, disposition, injury location and consumer product associated with injury were collected. Read More

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Current Management of Age-Related Macular Degeneration.

Adv Exp Med Biol 2021 ;1256:295-314

Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

Age-related macular degeneration (AMD) remains a leading cause of blindness worldwide. The assessment and management of patients with this condition has evolved in the last decades. In this chapter, current standards for diagnosis, follow-up, and treatment of patients with AMD are reviewed and summarized. Read More

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January 2021

The kebab technique uses a bipolar pencil to retrieve a dropped nucleus of the lens via a small incision.

Sci Rep 2021 Apr 12;11(1):7897. Epub 2021 Apr 12.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.

We developed a new method to retrieve a dropped nucleus of the lens via a small incision using bipolar pencils, the kebab technique, to solve the lack of small-gauge fragmatomes, and the expense and toxicity of perfluorocarbon liquids (PFCL). A total of 8 eyes in 6 patients underwent this technique and were reviewed. After vitrectomy, the dropped nucleus of the lens was lifted from the retina by adhesion with a bipolar pencil, and phacoemulsification was performed while rotating the lens. Read More

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Visual Performance and Optical Quality after Implantation of a New Generation Monofocal Intraocular Lens.

Korean J Ophthalmol 2021 Apr 5;35(2):112-119. Epub 2021 Apr 5.

Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea.

Purpose: To evaluate the performance of two intraocular lenses (IOLs). The new monofocal IOL using a higher-order aspheric optic (Tecnis Eyhance ICB00) was compared to a standard monofocal IOL (Tecnis monofocal ZCB00) of the identical platform and material.

Methods: The medical records of the patients who had undergone cataract surgery with implantation of either the ZCB00 or the ICB00 in the dominant eye from March 2020 to August 2020 and with available data from the 3-month visit were reviewed. Read More

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Outcome of cataract surgery in children affected by malignancies other than retinoblastoma with eye-lens radiation exposure.

Eur J Ophthalmol 2021 Apr 10:11206721211009445. Epub 2021 Apr 10.

San Paolo Ophthalmic Center, San Antonio Hospital - University Hospital, Padova, Italy.

Purpose: To describe, retrospectively, the visual outcome, feasibility, and safety of cataract surgery in a pediatric population affected by iatrogenic cataract, secondary to systemic oncological treatment for malignancies other than retinoblastoma.

Methods: Young patients, affected by radiation-induced cataract, who were referred to the San Paolo Ophthalmic Center in Padova between 2010 and 2017, were included in the study. All patients had previously received radiotherapy and/or chemotherapy treatment for malignancies, between 2004 and 2013. Read More

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Prevalence of subclinical retinal ischemia in patients with cardiovascular disease - a hypothesis driven study.

EClinicalMedicine 2021 Mar 2;33:100775. Epub 2021 Mar 2.

Department of Ophthalmology, University of California San Diego, La Jolla, California USA.

Background: Cardiovascular disease is the leading cause of mortality and disability worldwide. A noninvasive test that can detect underlying cardiovascular disease has the potential to identify patients at risk prior to the occurrence of adverse cardiovascular events. We sought to determine whether an easily observed imaging finding indicative of retinal ischemia, which we term ' (RIPLs), could serve as a biomarker for cardiovascular disease. Read More

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Safety of video-based telemedicine compared to in-person triage in emergency ophthalmology during COVID-19.

EClinicalMedicine 2021 Apr 5:100818. Epub 2021 Apr 5.

Department of Digital Medicine, Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, United Kingdom.

Background: the need for social distancing midst the COVID-19 pandemic has forced ophthalmologists to innovate with telemedicine. The novel process of triaging emergency ophthalmology patients via videoconsultations should reduce hospital attendances. However, the safety profile of such services were unknown. Read More

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Descemet Membrane Endothelial Keratoplasty Outcomes between Young and Old Graft Recipients.

Curr Eye Res 2021 Apr 11:1-7. Epub 2021 Apr 11.

Department of Ophthalmology, Rabin Medical Center, Petah-Tikva, Israel.

: To evaluated Descemet's membrane endothelial keratoplasty (DMEK) outcomes in young and old graft recipients.: Data of 164 surgeries with a median age of 76 years (interquartile range 14 years) undergoing DMEK surgery between 2016 and 2018 was reviewed. Complications, graft survival, and visual acuity gain were compared between subjects in the 25th percentile (young recipients; aged 70 years and less, n = 21) and 75th percentile (old recipients; aged 85 years and over, n = 27) over the 2-year follow-up. Read More

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Teleglaucoma Initiative at a Veterans Affairs Hospital: Pilot Safety Data and Early Experience.

Ophthalmol Glaucoma 2021 Apr 8. Epub 2021 Apr 8.

Department of Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Objective: To evaluate the safety, reliability and efficacy of telemedicine in delivering tertiary sub-specialty glaucoma care (herein referred to as teleglaucoma) to the Veteran patient population.

Study Design: Prospective case series.

Participants: 20 patients being referred for glaucoma sub-specialist opinion participated in the pilot safety study. Read More

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Sunlamp use is a risk factor for uveal melanoma: a meta-analysis.

Can J Ophthalmol 2021 Apr 8. Epub 2021 Apr 8.

Department of Surgery, Faculty of Medicine and Dentistry, University of Calgary, Calgary, Alb.

Objective: Advancements in the treatment of uveal melanoma have not improved survival; therefore, identifying modifiable risk factors is critical to improving outcomes. This study aims to investigate the association between sunlamp use and the development of uveal melanoma.

Design: This study is designed as a meta-analysis. Read More

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Comparative study of combined vitrectomy with phacoemulsification versus vitrectomy alone for primary full-thickness macular hole repair.

BMC Ophthalmol 2021 Apr 10;21(1):174. Epub 2021 Apr 10.

Department of Ophthalmology, Cantonal Hospital St. Gallen, Rorschacher Strasse 95, 9007, St. Gallen, Switzerland.

Background: To assess the effectiveness and safety of 23-gauge pars plana vitrectomy combined with phacoemulsification versus vitrectomy alone in patients over 50 years with primary full-thickness macular holes (FTMH).

Methods: We retrospectively reviewed the medical records related to 406 consecutive vitrectomies performed for primary FTMH. Phacovitrectomy was performed in 294 phakic eyes whereas vitrectomy alone in 112 pseudophakic eyes. Read More

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Long-term ocular biometric variations after scleral buckling surgery in macula-on rhegmatogenous retinal detachment.

BMC Ophthalmol 2021 Apr 10;21(1):172. Epub 2021 Apr 10.

Ophthalmology Unit - Department of Sense Organs, Sapienza University of Rome - Policlinico Umberto I University Hospital, Rome, Italy.

Background: Myopic shift and biometric ocular changes have been previously observed after scleral buckling (SB) surgery in rhegmatogenous retinal detachment (RRD), but long term-term outcomes had not yet been explored. The purpose of present study is to evaluate long term ocular biometric changes in patients with primary macula-on RRD treated with SB.

Methods: In this retrospective, observational study, we reviewed the medical records of patients undergoing SB surgery for macula-on RRD. Read More

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A comparative study of functioning and non-functioning pituitary adenomas.

Medicine (Baltimore) 2021 Apr;100(14):e25306

Department of Ophthalmology, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Xi Cheng District.

Abstract: Pituitary tumors commonly cause visual impairment and the degree of impairment can depend on the size, location, and type of the tumor. However, no studies have been made regarding the differences caused by functioning pituitary adenoma (FPA) and non-functioning pituitary adenoma (NFPA). We aimed to investigate the relationship between clinical characteristics and visual impairment in patients with FPA and NFPA. Read More

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Corneal transplantation activity in Catalonia, Spain, from 2011 to 2018: Evolution of indications and surgical techniques.

PLoS One 2021 8;16(4):e0249946. Epub 2021 Apr 8.

Institut Clinic d'Oftalmologia (ICOF), Hospital Clinic de Barcelona, Barcelona, Spain.

Purpose: To report corneal transplant activity carried out in Catalonia (Spain) and the evolving indications for keratoplasty over an 8-year period.

Methods: Annual reports from the Catalan Transplant Organization, Spain, on corneal graft indications and techniques from 2011 to 2018 were reviewed.

Results: A total of 9457 keratoplasties were performed in Catalonia, from January 2011 to December 2018. Read More

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A meta-analysis and systematic review of changes in joint position sense and static standing balance in patients with whiplash-associated disorder.

PLoS One 2021 8;16(4):e0249659. Epub 2021 Apr 8.

Centre of Precision Rehabilitation for Spinal Pain (CPR Spine), School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Objective: To synthesise and analyse the current evidence regarding changes in joint position sense (JPS) and standing balance in people with whiplash-associated disorder (WAD) taking the presence or absence of dizziness into account.

Data Sources: PubMed, CINAHL Plus, Web of Science, Embase, MEDLINE and APA PsycINFO were searched by two independent reviewers from inception until August 2020 and reference lists of all included studies were also reviewed.

Study Selection: Only cross-sectional studies that measured JPS and/or standing balance between people with WAD vs. Read More

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Proton Beam Therapy in the Treatment of Periorbital Malignancies.

Int J Part Ther 2021 26;7(4):42-51. Epub 2021 Mar 26.

Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.

Purpose: Periorbital tumor location presents a significant challenge with 3-dimensional conformal radiation therapy or intensity modulated radiation therapy due to high tumor dose needed in the setting of close proximity to orbital structures with lower tolerance. Proton beam therapy (PBT) is felt to be an effective modality in such cases due to its sharp dose gradient.

Materials And Methods: We reviewed our institutional PBT registry and identified 17 patients with tumor epicenters within 2 cm of the eye and optic apparatus treated with passive scatter PBT with comparison volumetric arc therapy plans available. Read More

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Diagnostic accuracy of deep learning in medical imaging: a systematic review and meta-analysis.

NPJ Digit Med 2021 Apr 7;4(1):65. Epub 2021 Apr 7.

Institute of Global Health Innovation, Imperial College London, London, UK.

Deep learning (DL) has the potential to transform medical diagnostics. However, the diagnostic accuracy of DL is uncertain. Our aim was to evaluate the diagnostic accuracy of DL algorithms to identify pathology in medical imaging. Read More

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Relationship between retinal sensitivities and optical coherence tomographic findings in eyes with myopic chorioretinal atrophy.

Eur J Ophthalmol 2021 Apr 7:11206721211008038. Epub 2021 Apr 7.

Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.

Purpose: To determine whether there is a significant correlation between the retinal sensitivity and the integrity of the ellipsoid zone (EZ) of the photoreceptors in eyes with myopic chorioretinal atrophy (CRA). We also determined the significance of the correlation between the retinal sensitivity and the retinal and choroidal thicknesses.

Methods: The medical records of 10 eyes of six subjects with myopic CRA were reviewed. Read More

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Estimating the Prevalence of Mental and Substance Use Disorders: A Systematic Approach to Triangulating Available Data to Inform Health Systems Planning:: Estimer la prévalence des troubles mentaux et des troubles liés à une substance: une approche systématique de la triangulation des données disponibles pour éclairer la planification du système de santé.

Can J Psychiatry 2021 Apr 8:7067437211006872. Epub 2021 Apr 8.

Centre for Applied Research in Mental Health and Addictions, Simon Fraser University, Vancouver, British Columbia, Canada.

Objective: To estimate the prevalence of specific mental and substance use disorders (MSUDs), by age and sex, as a first step toward informing needs-based health systems planning by decision-makers.

Methods: We developed a conceptual framework and a systematic methodology for combining available data sources to yield prevalence estimates for specific MSUDs. Data sources used included published, peer-reviewed literature from Canada and comparable countries, Canadian population survey data, and health administrative data from British Columbia. Read More

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Report of a cluster of cases of toxic anterior-segment syndrome after implantation of a specific intraocular lens model.

Am J Ophthalmol 2021 Apr 4. Epub 2021 Apr 4.

Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan.

Purpose: To report a cluster of cases of toxic anterior-segment syndrome (TASS) in eyes implanted with a specific foldable acrylic intraocular lens (IOL) model.

Design: Retrospective case series.

Methods: The medical records were reviewed for seven eyes of four patients diagnosed with TASS after cataract surgery at Shimane University and Matsue Red Cross Hospital between July and November 2020. Read More

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Refractive outcome of trocar-assisted sutureless scleral fixation with 3-piece intraocular lenses.

Int Ophthalmol 2021 Apr 7. Epub 2021 Apr 7.

Department of Ophthalmology, Faculty of Medicine, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Kadikoy, Istanbul, Turkey.

Purpose: Intraocular lens (IOL) implantation with a trocar-assisted sutureless scleral fixation technique is a relatively new IOL implantation approach for aphakic eyes. During this surgery, the intrascleral position of the haptics can change the location of the IOL optic and may alter the refractive outcome. This study aimed to evaluate the refractive outcome of this surgery. Read More

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Photodynamic therapy as a treatment option for peripapillary pachychoroid syndrome: a pilot study.

Eye (Lond) 2021 Apr 6. Epub 2021 Apr 6.

Division of Ophthalmology, Tel Aviv Sourasky Medical Center affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: To investigate the anatomical and functional results in eyes with peripapillary pachychoroid syndrome (PPS) undergoing photodynamic therapy (PDT).

Methods: A total of 25 eyes from 23 patients with PPS treated with PDT were retrospectively evaluated in this multicentric study. Main outcome measure was the proportion of eyes that achieved treatment success, defined as a decrease in both subretinal fluid (SRF) height and central subfield thickness (CST), at 3 months after PDT compared to baseline. Read More

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Depression in disabling medical conditions - current perspectives.

Int Rev Psychiatry 2021 Apr 6:1-14. Epub 2021 Apr 6.

School of Health and Social Care, University of Essex, Colchester, UK.

Chronic diseases commonly entail disability and are highly comorbid with mental health problems, particularly depression. Prevalence of depression across different disabling conditions affecting adult patients, as well as risk factors for depression in these patient groups are reviewed in the current work, with a particular focus on the literature published in the past 5 years. The prevalence of depression in disabling conditions is higher than in the general population and is associated with different factors. Read More

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Lamellar corneal patch grafts in the management of corneal thinning and perforations without using extra corneas.

Semin Ophthalmol 2021 Apr 6:1-4. Epub 2021 Apr 6.

Beyoglu Research and Training Hospital, Ophtalmology Department, Istanbul, Turkey.

Objectives: To report the tectonic role of circular and square-shaped lamellar grafts without using extra corneas.

Materials And Methods: We retrospectively reviewed 23 lamellar patch grafts performed over a six-year period for various tectonic indications in corneal thinning and perforations. The anterior stroma of corneal endothelium peeled for Descemet Membrane Endothelial Keratoplasty were used to prepare circular lamellar corneal grafts. Read More

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CRISPR Cas9 based genome editing in inherited retinal dystrophies.

Ophthalmic Genet 2021 Apr 6:1-10. Epub 2021 Apr 6.

Council of Scientific and Industrial Research - Institute of Genomics & Integrative Biology, New Delhi, India.

Background: Precision genome engineering, with targeted therapy towards patient-specific mutations is predicted to be the future of personalized medicine. Ophthalmology is in the frontiers of development of targeted therapy since the eye is an accessible organ and has the ease of both delivery as well as monitoring effects of therapy.

Materials And Methods: We reviewed literature using keywords CRISPR, precision medicine, genomic editing, retinal dystrophies, retinitis pigmentosa, Usher syndrome, Stargardt's Disease. Read More

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Microvascular comparison in younger and older patients with retinal vein occlusion analyzed by OCT angiography.

BMC Ophthalmol 2021 Apr 5;21(1):161. Epub 2021 Apr 5.

Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, No.88, Jiefang Road, 310009, Hangzhou, China.

Background: To compare changes in retinal microvasculature of young and elderly patients with retinal vein occlusion (RVO) after anti-VEGF treatment.

Methods: RVO patients who underwent anti-VEGF treatment were retrospectively reviewed and categorized into two groups based on age. The OCT angiography images were obtained during each visit. Read More

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Incidence of Endophthalmitis after Intravitreal Anti-Vascular Endothelial Growth Factor Injections in an Operating Room in China.

J Ophthalmol 2020 12;2020:5163484. Epub 2020 Nov 12.

Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Purpose: To evaluate the rate of presumed endophthalmitis (EO) after intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections performed in an operating room (OR) under sterile conditions in mainland China.

Methods: Retrospective single-center study between September 2012 and December 2017 at Beijing Tongren Eye Center, Beijing, China. Intravitreal injection database was reviewed. Read More

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November 2020

Study protocol for a multicentre, randomised controlled trial to compare the use of the decellularised dermis allograft in addition to standard care versus standard care alone for the treatment of venous leg ulceration: DAVE trial.

BMJ Open 2021 Apr 2;11(4):e041748. Epub 2021 Apr 2.

Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK

Introduction: Venous leg ulceration (VLU), the most common type of chronic ulcer, can be difficult to heal and is a major cause of morbidity and reduced quality of life. Although compression bandaging is the principal treatment, it is time-consuming and bandage application requires specific training. There is evidence that intervention on superficial venous incompetence can help ulcer healing and recurrence, but this is not accessible to all patients. Read More

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