49,490 results match your criteria review summarized


Prevalence of HIV, hepatitis B virus, and hepatitis C virus among incarcerated people in Iran: a systematic review and meta-analysis.

Public Health 2022 Jan 12;203:75-82. Epub 2022 Jan 12.

HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

Objectives: Incarcerated people are at higher risk for HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) infections. This review systematically summarized the evidence on the prevalence of these infections among incarcerated people in Iran.

Study Design: A systematic review and meta-analysis. Read More

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January 2022

Degradation of toxic agrochemicals and pharmaceutical pollutants: Effective and alternative approaches toward photocatalysis.

Environ Pollut 2022 Jan 12:118844. Epub 2022 Jan 12.

Department of Biotechnology, Rajalakshmi Engineering College, Chennai, 602105, India.

Emerging concern regarding the remediation of environmental pollution has expanded tremendously in recent years. Pharmaceutical industries and agricultural sectors release an enormous amount of residues containing toxic pollutants at trace levels which poses a serious impact on the environment and human health. To cope with the effect of hazardous and toxic contaminants, numerous methodologies have been developed for the treatment of effluents released from the agrochemical and pharmaceutical industries. Read More

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January 2022

Activation-induced cell death in CAR-T cell therapy.

Hum Cell 2022 Jan 15. Epub 2022 Jan 15.

School of Life Sciences, Jiangsu University, 301 Xuefu Road, Zhenjiang, 212013, Jiangsu, China.

Engineered T cells expressing chimeric antigen receptors (CARs) with tumor specificity have shown remarkable therapeutic effects on hematologic malignancies. However, CAR-T cells are less effective on solid tumors mainly due to the weak persistence of CAR-T cells, which might be caused by T cell death. Significant activation-induced cell death (AICD) of CAR-T cells was triggered by repeated antigen stimulation. Read More

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January 2022

Perovskite Quantum Dots in Solar Cells.

Adv Sci (Weinh) 2022 Jan 14:e2104577. Epub 2022 Jan 14.

Dalian National Laboratory for Clean Energy, iChEM, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning, 116023, China.

Perovskite quantum dots (PQDs) have captured a host of researchers' attention due to their unique properties, which have been introduced to lots of optoelectronics areas, such as light-emitting diodes, lasers, photodetectors, and solar cells. Herein, the authors aim at reviewing the achievements of PQDs applied to solar cells in recent years. The engineering concerning surface ligands, additives, and hybrid composition for PQDSCs is outlined first, followed by analyzing the reasons of undesired performance of PQDSCs. Read More

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January 2022

Understanding the key factors determining rural domestic waste treatment behavior in China: a meta-analysis.

Environ Sci Pollut Res Int 2022 Jan 15. Epub 2022 Jan 15.

College of Economics and Management, Northwest A&F University, Xianyang, 712100, Yangling, China.

The growing interest of policy-makers, environmental stakeholders, and academics in rural domestic waste treatment has made it a recent focus of research in the field of rural human settlements. Many studies have been conducted to understand the related factors; however, their results are inconsistent. Therefore, different from previous studies, the study systematically analyzed and summarized empirical studies on rural domestic waste treatment and explored the key factors that fostered and impeded it. Read More

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January 2022

Zebrafish Xenotransplantation Models for Studying Gene Function and Drug Treatment in Hepatocellular Carcinoma.

J Gastrointest Cancer 2022 Jan 15. Epub 2022 Jan 15.

Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.

Introduction: Zebrafish is a promising model organism for human disease including hepatocellular cancer (HCC). Recently, zebrafish has emerged also as a host for xenograft studies of liver cancer cell lines and patient derived tumors of HCC. Zebrafish embryos enable drug screening and gene function studies of xenografted cells via ease of microinjection and visualization of tumor growth and metastasis. Read More

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January 2022

Aerosolization of fungal spores in indoor environments.

Sci Total Environ 2022 Jan 11:153003. Epub 2022 Jan 11.

School of Civil Engineering and Architecture, Linyi University, Linyi 276000, China.

Fungi in indoor environments can cause adverse health effects through inhalation and epidermal exposure. The risk of fungal exposure originates from the aerosolization of fungal spores. However, spore aerosolization is still not well understood. Read More

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January 2022

A review on characterizing the metabolite property of anammox sludge by spectroscopy.

Sci Total Environ 2022 Jan 11:153065. Epub 2022 Jan 11.

School of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China. Electronic address:

As one of the most promising autotrophic biological nitrogen removal technology, anaerobic ammonia oxidation (anammox) has gained intense attention for the past decades and several full-scale facilities have been implemented worldwide. However, anammox bacteria are easily affected by disturbed external environmental factors, which commonly leads to the fluctuations in reactor performance. The response of anammox sludge to external stress results in changes in components and structural characteristics of intracellular and extracellular polymer substances. Read More

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January 2022

Postmarketing safety surveillance of high-dose quadrivalent influenza vaccine: Reports to the Vaccine Adverse Event Reporting System.

Vaccine 2022 Jan 11. Epub 2022 Jan 11.

Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address:

On November 4, 2019, the Food and Drug Administration approved high-dose quadrivalent influenza vaccine (Fluzone High-Dose Quadrivalent; QIV-HD) for active immunization for the prevention of influenza disease in individuals 65 years of age and older. A prelicensure randomized, active-controlled, modified double-blind trial did not reveal any major differences in adverse events following QIV-HD versus Fluzone High-Dose (trivalent). To improve our understanding of the safety profile of QIV-HD, we reviewed and summarized reports of adverse events after QIV-HD to the Vaccine Adverse Event Reporting System (VAERS). Read More

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January 2022

A Systematic Review of Health Technology Assessments of Chimeric Antigen Receptor T-Cell Therapies in Young Compared With Older Patients.

Value Health 2022 Jan 28;25(1):47-58. Epub 2021 Aug 28.

Centre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.

Objectives: The objective of this review was to identify sources of variability in cost-effectiveness analyses of chimeric antigen receptor T-cell (CAR-T) therapies, tisagenlecleucel and axicabtagene ciloleucel, evaluated by health technology assessment (HTA) agencies, focusing on young compared with older patients.

Methods: HTA evaluations in pediatric acute lymphoblastic leukemia (ALL) and adult diffuse large B-cell lymphoma (DLBCL) were included from Australia, Canada, England, Norway, and the United States. Key clinical evidence, economic approach, and outcomes (costs, quality-adjusted life-years [QALYs] and incremental cost-effectiveness ratios) were summarized. Read More

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January 2022

Properties, optimized morphologies, and advanced strategies for photocatalytic applications of WO based photocatalysts.

J Hazard Mater 2022 Jan 7;428:128218. Epub 2022 Jan 7.

Department of Chemical and Biological Engineering, University of British Columbia, 2360 East Mall, Vancouver, BC V6P 1Z3, Canada. Electronic address:

The development of WO based photocatalysts has gained considerable attention across the world, especially in the realm of environmental remediation and energy production. WO has a band gap of 2.5- 2. Read More

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January 2022

Engineering strategies towards overcoming bleeding and glial scar formation around neural probes.

Cell Tissue Res 2022 Jan 14. Epub 2022 Jan 14.

Department of Microsystems Engineering (IMTEK), University of Freiburg, Georges-Köhler Allee 201, 79110, Freiburg, Germany.

Neural probes are sophisticated electrophysiological tools used for intra-cortical recording and stimulation. These microelectrode arrays, designed to penetrate and interface the brain from within, contribute at the forefront of basic and clinical neuroscience. However, one of the challenges and currently most significant limitations is their 'seamless' long-term integration into the surrounding brain tissue. Read More

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January 2022

Human-Centered Design of Mobile Health Apps for Older Adults: Systematic Review and Narrative Synthesis.

JMIR Mhealth Uhealth 2022 Jan 14;10(1):e29512. Epub 2022 Jan 14.

Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: The world is aging. The number of older patients is on the rise, and along with it comes the burden of noncommunicable diseases, both clinical and economic. Attempts with mobile health (mHealth) have been made to remedy the situation with promising outcomes. Read More

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January 2022

The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis.

JMIR Serious Games 2022 Jan 14;10(1):e32331. Epub 2022 Jan 14.

Division of Information and Computing Technology, College of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar.

Background: Depression is a common mental disorder characterized by disturbances in mood, thoughts, or behaviors. Serious games, which are games that have a purpose other than entertainment, have been used as a nonpharmacological therapeutic intervention for depression. Previous systematic reviews have summarized evidence of effectiveness of serious games in reducing depression symptoms; however, they are limited by design and methodological shortcomings. Read More

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January 2022

Machine Learning Models for Predicting Cytotoxicity of Nanomaterials.

Chem Res Toxicol 2022 Jan 14. Epub 2022 Jan 14.

National Center for Toxicological Research, United States Food and Drug Administration, Jefferson, Arkansas 72079, United States.

The wide application of nanomaterials in consumer and medical products has raised concerns about their potential adverse effects on human health. Thus, more and more biological assessments regarding the toxicity of nanomaterials have been performed. However, the different ways the evaluations were performed, such as the utilized assays, cell lines, and the differences of the produced nanoparticles, make it difficult for scientists to analyze and effectively compare toxicities of nanomaterials. Read More

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January 2022

Potential Application of Exosomes in Vaccine Development and Delivery.

Pharm Res 2022 Jan 13. Epub 2022 Jan 13.

Department of Pharmaceutical Sciences, University of Texas at El Paso School of Pharmacy, 1101 N. Campbell St, El Paso, TX, 79902, USA.

Exosomes are cell-derived components composed of proteins, lipid, genetic information, cytokines, and growth factors. They play a vital role in immune modulation, cell-cell communication, and response to inflammation. Immune modulation has downstream effects on the regeneration of damaged tissue, promoting survival and repair of damaged resident cells, and promoting the tumor microenvironment via growth factors, antigens, and signaling molecules. Read More

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January 2022

Recent advances in preventing neurodegenerative diseases.

Fac Rev 2021 1;10:81. Epub 2021 Dec 1.

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, 733 North Broadway, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

The worldwide health-care burden of neurodegenerative diseases is on the rise-a crisis created through a combination of increased caseload and lack of effective treatments. The limitations of pharmacotherapy in these disorders have led to an urgent shift toward research and clinical trials for the development of novel compounds, interventions, and methods that target shared features across the spectrum of neurodegenerative diseases. Research targets include neuronal cell death, mitochondrial dysfunction, protein aggregation, and neuroinflammation. Read More

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December 2021

Pediatric Upper Cervical Spine Trauma: A 10-Year Retrospective Review at a Pediatric Trauma Center.

Cureus 2022 Jan 6;14(1):e20995. Epub 2022 Jan 6.

Department of Orthopedic Surgery, Oakland University William Beaumont School of Medicine, Rochester, USA.

Background Traumatic upper cervical spine injuries (tUCSI) are generally caused by high-impact injuries to the C1-C2 vertebral level. The current literature is limited with regards to comparing epidemiological trends, treatment options, and overall outcomes for tUCSI within the pediatric cohort. The purpose of this study was to analyze pediatric tUCSI epidemiological data, potential variations in treatment and patient outcomes, and to evaluate any specific trends that may be clinically relevant. Read More

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January 2022

Expression of Prostate Specific Membrane Antigen (PSMA) in Breast Cancer.

Geburtshilfe Frauenheilkd 2022 Jan 10;82(1):50-58. Epub 2022 Jan 10.

Klinik für Frauenheilkunde, Universitätsklinikum Freiburg, Freiburg, Germany.

Prostate specific membrane antigen (PSMA) is a promising protein for breast cancer patients. It has not only been detected in prostate cancer but is also expressed by tumor cells and the endothelial cells of tumor vessels in breast cancer patients. PSMA plays a role in tumor progression and tumor angiogenesis. Read More

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January 2022

Applications of artificial intelligence in the diagnosis and prediction of erectile dysfunction: a narrative review.

Int J Impot Res 2022 Jan 13. Epub 2022 Jan 13.

Andrology Laboratory, West China Hospital, Sichuan University, Chengdu, China.

Despite the high prevalence of erectile dysfunction, patients are reluctant to seek medical advice, which leads to low diagnostic rates in clinical practice. Artificial intelligence has been widely applied in the diagnosis of many diseases and may alleviate the situation. However, the applications of artificial intelligence in erectile dysfunction have not been reviewed to date. Read More

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January 2022

Biportal Endoscopic Technique for Transforaminal Lumbar Interbody Fusion: Review of Current Research.

Int J Spine Surg 2021 Dec;15(suppl 3):S84-S92

Department of Orthopedics and Neurosurgery, Endoscopic Spine Surgery Center, Bumin Hospital Seoul, Seoul, Republic of Korea.

Background: There are many types of minimally invasive lumbar interbody fusion procedures. Among them is the recently introduced biportal endoscopic lumbar interbody fusion surgery. Biportal endoscopic transforaminal lumbar interbody fusion (TLIF) might combine the advantages of minimally invasive TLIF and endoscopic spine approaches. Read More

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December 2021

A Review of Unilateral Biportal Endoscopic Decompression for Degenerative Lumbar Canal Stenosis.

Authors:
Jwo-Luen Pao

Int J Spine Surg 2021 Dec;15(suppl 3):S65-S71

Department of Orthopedic Surgery, Far-Eastern Memorial Hospital, New Taipei, Taiwan

Background: The unilateral biportal endoscopic (UBE) technique provides minimally invasive decompression for degenerative lumbar canal stenosis (DLCS). With appropriate control of the hydrostatic pressure of normal saline irrigation, the surgery can be performed in a clear and magnified surgical field through 2 small surgical wounds.

Methods: A review of published literature in PubMed was performed to identify studies of UBE decompression for DLCS. Read More

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December 2021

Potential therapeutic options for COVID-19: an update on current evidence.

Eur J Med Res 2022 Jan 13;27(1). Epub 2022 Jan 13.

Department of Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19 pandemic and is a major public health concern nowadays. The rapid and global spread of this coronavirus leads to an increase in hospitalizations and thousands of deaths in many countries. To date, great efforts have been made worldwide for the efficient management of this crisis, but there is still no effective and specific treatment for COVID-19. Read More

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January 2022

Primary low-grade extrauterine endometrial stromal sarcoma: analysis of 10 cases with a review of the literature.

World J Surg Oncol 2022 Jan 13;20(1):17. Epub 2022 Jan 13.

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Pan Jia Yuan Street, Chao Yang District, Beijing, 100021, China.

Background: This study aimed to analyze the clinical and pathological features of extrauterine endometrial stromal sarcoma (EESS) and explore an effective therapeutic regimen to reduce the recurrence rate in low-grade EESS patients.

Methods: Ten LG-EESS patients who were treated at the Chinese Academy of Medical Sciences Cancer Institute and Hospital from June 1999 to June 2019 were collected and analyzed.

Results: (1) Patient demographics are summarized in manuscript. Read More

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January 2022

Ginseng in vascular dysfunction: A review of therapeutic potentials and molecular mechanisms.

Phytother Res 2022 Jan 13. Epub 2022 Jan 13.

Jilin Ginseng Academy, Key Laboratory of Active Substances and Biological Mechanisms of Ginseng Efficacy, Ministry of Education, Jilin Provincial Key Laboratory of Bio-Macromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.

Vascular dysfunction can lead to a variety of fatal diseases, including cardiovascular and cerebrovascular diseases, metabolic syndrome, and cancer. Although a large number of studies have reported the therapeutic effects of natural compounds on vascular-related diseases, ginseng is still the focus of research. Ginseng and its active substances have bioactive effects against different diseases with vascular dysfunction. Read More

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January 2022

Neuroimaging Prediction of Hemorrhagic Transformation for Acute Ischemic Stroke.

Cerebrovasc Dis 2022 Jan 13:1-11. Epub 2022 Jan 13.

Department of Neurology, National Center for Neurological Disorders, National Clinical Research Centre for Aging and Medicine, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.

Background: Hemorrhagic transformation (HT) is a common complication of acute ischemic stroke, often resulting from reperfusion therapy. Early prediction of HT can enable stroke neurologists to undertake measures to avoid clinical deterioration and make optimal treatment strategies. Moreover, the trend of extending the time window for reperfusion therapy (both for intravenous thrombolysis and endovascular treatment) further requires more precise detection of HT tendency. Read More

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January 2022

Maternal lifestyle factors and risk of neuroblastoma in the offspring: A meta-analysis including Greek NARECHEM-ST primary data.

Cancer Epidemiol 2022 Jan 11;77:102055. Epub 2022 Jan 11.

Hellenic Society for Social Pediatrics and Health Promotion, Athens, Greece; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Greece. Electronic address:

The etiology of childhood neuroblastoma remains largely unknown. In this systematic review and meta-analysis, we summarized and quantitatively synthesized published evidence on the association of maternal modifiable lifestyle factors with neuroblastoma risk in the offspring. We searched MEDLINE up to December 31, 2020 for eligible studies assessing the association of maternal smoking, alcohol consumption and nutritional supplementation during pregnancy with childhood (0-14 years) neuroblastoma risk. Read More

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January 2022

Advanced detection and sensing strategies of Pseudomonas aeruginosa and quorum sensing biomarkers: A review.

Talanta 2022 Jan 7;240:123210. Epub 2022 Jan 7.

The Affiliated Hospital of Medical School, Ningbo University, Ningbo, Zhejiang Province, 315211, People's Republic of China; Department of Preventative Medicine, Zhejiang Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province, 315211, People's Republic of China. Electronic address:

Pseudomonas aeruginosa (P. aeruginosa), a ubiquitous opportunistic pathogen, can frequently cause chronic obstructive pulmonary disease, cystic fibrosis and chronic wounds, and potentially lead to severe morbidity and mortality. Timely and adequate treatment of nosocomial infection in clinic depends on rapid detection and accurate identification of P. Read More

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January 2022

Genus Lonicera: New drug discovery from traditional usage to modern chemical and pharmacological research.

Phytomedicine 2021 Dec 20;96:153889. Epub 2021 Dec 20.

Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong 518020, China; Department of Pathology (Longhua Branch), Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong 518020, China; Guangdong Provincial Key Laboratory of Regional Immunity and Diseases, Medicine School of Shenzhen University, Shenzhen, Guangdong 518037, China. Electronic address:

Background: Lonicera Linn. belonging to the family Caprifoliaceae, the largest genus in the plant family, includes about more than 200 species, which are mainly distributed in northern Africa, North America, Europe and Asia. Some species of this genus have been usually used in traditional Chinese medicine as well as functional foods, cosmetics and other applications, such as L. Read More

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December 2021

Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment.

Biotechnol Adv 2022 Jan 10:107902. Epub 2022 Jan 10.

State Key Laboratory of Food Science and Technology, School of Food Science and Technology, International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China; Key Laboratory of Meat Processing of Sichuan, Chengdu University, Chengdu 610106, China. Electronic address:

Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized libraries, presenting high affinity and specificity toward targets with similar to antibodies. Recently, aptamers have demonstrated their outstanding application potential ranging from biosensors, bioimaging, and therapeutics due to various advantages including low immunogenicity, ease of large-scale synthesis, low batch-to-batch variation, easily chemical modification, and programmability. However, the current overall success rate of aptamer is far from being satisfactory, and still needs to overwhelm the major obstacle in affinity, specificity, and stability for practical application. Read More

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January 2022