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Media and social media attention to retracted articles according to Altmetric.

PLoS One 2021 12;16(5):e0248625. Epub 2021 May 12.

Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, United States of America.

The number of retracted articles has grown fast. However, the extent to which researchers and the public are made adequately aware of these retractions and how the media and social media respond to them remains unknown. Here, we aimed to evaluate the media and social media attention received by retracted articles and assess also the attention they receive post-retraction versus pre-retraction. Read More

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Validating a novel algorithm to identify patients with autoimmune hepatitis in an administrative database.

Pharmacoepidemiol Drug Saf 2021 May 12. Epub 2021 May 12.

Department of Medicine, Division of Digestive Health and Liver Disease, University of Miami Miller School of Medicine, Miami, FL.

Purpose: Population-level studies on the treatment practices and comparative effectiveness of therapies in autoimmune hepatitis (AIH) are lacking due to the absence of validated methods to identify patients with AIH in large databases, such as administrative claims or electronic health records. This study ascertained the performance of International Classification of Diseases (ICD) codes for AIH, and developed and validated a novel algorithm that reliably identifies patients with AIH in health administrative data and claims.

Methods: This was a cross-sectional study of patients with ≥1 inpatient or ≥2 outpatient ICD codes for AIH between 2008-2019 at a single health system. Read More

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Prevalence of Bacterial Meningitis Among Febrile Infants Aged 29-60 Days With Positive Urinalysis Results: A Systematic Review and Meta-analysis.

JAMA Netw Open 2021 May 3;4(5):e214544. Epub 2021 May 3.

Division of Pediatric Emergency Medicine, Department of Pediatrics, British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Importance: Fever in the first months of life remains one of the most common pediatric problems. Urinary tract infections are the most frequent serious bacterial infections in this population. All published guidelines and quality initiatives for febrile young infants recommend lumbar puncture (LP) and cerebrospinal fluid (CSF) testing on the basis of a positive urinalysis result to exclude bacterial meningitis as a cause. Read More

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Expanding role of radiotherapy in adenoid cystic carcinoma of the tracheobronchial tree: a new horizon.

Tumori 2021 May 12:3008916211012461. Epub 2021 May 12.

Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Background: Primary adenoid cystic carcinomas (ACCs) of central trachea-bronchi system are rare and heterogeneous tumors. Definitive radiotherapy (RT) is the recommended treatment in surgically unresectable or incomplete resection or in the presence of severe comorbidities.

Objective: To evaluate the clinical features and outcomes of patients with ACC of trachea-bronchi treated with radiotherapy. Read More

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Delivery of systemic anti-cancer therapy during the COVID-19 pandemic.

Ir J Med Sci 2021 May 12. Epub 2021 May 12.

Medical Oncology Department, Beaumont Hospital, Dublin, Ireland.

Background: The first confirmed case of COVID-19 in Ireland was on February 29th 2020. From March until late April, the number of cases increased exponentially. The delivery of anti-cancer therapy during the COVID-19 pandemic was extremely challenging. Read More

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Expanding the Spectrum of Movement Disorders Associated With Hexanucleotide Expansions.

Neurol Genet 2021 Apr 12;7(2):e575. Epub 2021 Mar 12.

Department of Neurodegenerative Diseases (C.E.-F., D.H.M., S.J.T.), Department of Clinical and Movement Neurosciences (A.L, F.M., E.M., G.D.L., M.M., K.P.B.), and Department of Neuromuscular Disorders (H.H.), UCL Queen Square Institute of Neurology, United Kingdom; Department of Neurosciences, Biomedicine and Movement Sciences (F.M.), University of Verona, Italy; St George's University of London (D.H.M.), United Kingdom; Department of Systems Medicine (G.D.L.), University of Rome Tor Vergata, Italy; and Pacific Parkinson's Research Centre and Djavad Mowafaghian Centre for Brain Health (M.M.), University of British Columbia, Vancouver, Canada.

Objective: Hexanucleotide repeat expansions (HREs) in are a major cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). We aimed to determine the frequency and phenomenology of movement disorders (MD) in carriers of HRE in through a retrospective review of patients' medical records.

Methods: We retrospectively reviewed the clinical records of patients carrying a HRE in the pathogenic range and compared the characteristics of patients with and without MD. Read More

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Qualitative Interdisciplinary Learning Reviews of Non-COVID-19 Patients' Journeys During the COVID-19 Pandemic.

Cureus 2021 Apr 9;13(4):e14378. Epub 2021 Apr 9.

Quality and Patient Safety, Vancouver Coastal Health, Richmond, CAN.

In the early months of 2020, hospital processes were changed in response to the coronavirus disease 2019 (COVID-19) pandemic. We present one community hospital's experience in conducting a series of interdisciplinary learning reviews (ILRs) on non-COVID-19 patient's journeys during the early months of the pandemic. An ILR is a method of reviewing medical records using a system lens to identify system-level opportunities for improvement. Read More

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Clinical characteristics of COVID-19 patients admitted at the Korle-Bu Teaching Hospital, Accra, Ghana.

Ghana Med J 2020 Dec;54(4 Suppl):33-38

Department of Medicine and Therapeutics, University of Ghana Medical School, University of Ghana, Accra, Ghana.

The study examined the clinical characteristics and outcomes of 2019 novel coronavirus disease (COVID-19) infections among hospitalized patients.

Design: Study design was a retrospective single-center review of hospital data.

Setting: The study was conducted at the COVID-19 Treatment Center of the Department of Medicine and Therapeutics of the Korle-Bu Teaching hospital in Accra, Ghana. Read More

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December 2020

End-stage kidney disease and rationing of kidney replacement therapy in the free state province, South Africa: a retrospective study.

BMC Nephrol 2021 May 11;22(1):174. Epub 2021 May 11.

Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa.

Background: End-stage kidney disease (ESKD) and the required kidney replacement therapy (KRT) are significant public health challenges for low-and-middle-income countries. The South African government adopted a KRT rationing policy to balance the growing need for KRT and scarce resources. We aimed to describe the epidemiology and KRT access in patients with ESKD referred to the main public sector hospital in the Free State Province, South Africa. Read More

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Psychocutaneous Medicine Clinic; Wisconsin experience.

Ladan Mostaghimi

J Acad Consult Liaison Psychiatry 2021 May 8. Epub 2021 May 8.

Director of Wisconsin Psychocutaneous Clinic, Honorary Associate/fellow of Letter &Science/Integrative Biology UW Madison, Professor Emerita of the University of Wisconsin Madison. Electronic address:

Background: Psychocutaneous medicine, also known as psychodermatology, is a subspecialty of dermatology and psychiatry that explores the interactions between the skin and the brain. For many patients, skin disease affects their quality of life and mental wellbeing. For others, psychiatric problems exhibit skin signs. Read More

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Relationships Between Daily Device Use and Early Communication Outcomes in Young Children With Cochlear Implants.

Ear Hear 2021 Jan 6. Epub 2021 Jan 6.

1Department of Speech, Language, and Hearing, School of Behavioral and Brain Science, The University of Texas at Dallas, Richardson, Texas, USA 2Pediatric Cochlear Implant Program, Callier Center for Communication Disorders, Dallas, Texas, USA.

Objectives: Children with significant hearing loss can gain access to sound via a cochlear implant (CI), but they must wear the device to reap the communication benefits of the device. That is, poor daily device use may result in underdeveloped perceptual and language skills in children and adolescents using CIs. This retrospective study focuses on the relationship between daily CI use and communication performance (auditory skills, speech recognition, expressive and receptive language) in young children, with the hypothesis that greater daily device use coincides with better communication outcomes. Read More

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January 2021

Rate of glycemic control and associated factors among type two diabetes mellitus patients in Ethiopia: A cross sectional study.

PLoS One 2021 11;16(5):e0251506. Epub 2021 May 11.

Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Objective: To assess the rate of glycemic control and associated factors among type 2 diabetes mellitus patients at Dilchora Referral Hospital, Dire Dawa, Eastern Ethiopia.

Methods: A cross-sectional study was conducted from 13 May to 16 August 2019. Type 2 diabetic patients on follow up at Dilchora Referral Hospital who fulfilled the inclusion criteria of the study were included. Read More

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Measuring Multimorbidity: Selecting the Right Instrument for the Purpose and the Data Source.

Med Care 2021 May 11. Epub 2021 May 11.

Behavioral Research Program, National Cancer Institute, Bethesda, MD Institute for Health Research, Kaiser Permanente Colorado Department of Family Medicine, University of Colorado School of Medicine, Aurora, CO Complex Care Services, Division of General Pediatrics, Boston Children's Hospital Department of Pediatrics, Harvard Medical School, Boston, MA Center for Evidence and Practice Improvement, Agency for Healthcare Research and Quality, Rockville, MD Department of Epidemiology, S441A College of Public Health, University of Iowa, Iowa City, IA Office of Science Policy, Strategic Planning, Reporting, and Data, National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD Department of Family Medicine and Emergency Medicine, University of Sherbrooke, Chicoutimi, Quebec, QC, Canada Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH Department of Family Medicine, Oregon Health and Science University, Portland, OR Center for Outcomes Research, The Children's Hospital of Philadelphia, Philadelphia, PA Division of Health Care Statistics, National Center for Health Statistics, Hyattsville, MD Division of General Medicine, University of Michigan Medical School, Ann Arbor, MI Office of Behavioral and Social Sciences Research, National Institutes of Health Office of Disease Prevention, National Institutes of Health, Bethesda, MD.

Background: Adults have a higher prevalence of multimorbidity-or having multiple chronic health conditions-than having a single condition in isolation. Researchers, health care providers, and health policymakers find it challenging to decide upon the most appropriate assessment tool from the many available multimorbidity measures.

Objective: The objective of this study was to describe a broad range of instruments and data sources available to assess multimorbidity and offer guidance about selecting appropriate measures. Read More

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Alkhumra hemorrhagic fever virus infection.

Arch Virol 2021 May 11. Epub 2021 May 11.

Scientific Chair of Sheikh Mohammad Hussein Alamoudi for Viral Hemorrhagic Fever, King Abdulaziz University, Jeddah, Saudi Arabia.

Objectives: This review article summarizes what has been published on Alkhumra hemorrhagic fever virus (AHFV), a novel flavivirus that was discovered in Saudi Arabia in 1995.

Methods: PubMed was used to search for studies published from January 1995 to June 2019 using the key words Alkhumra virus, Alkhurma virus, novel flavivirus, and tick-borne encephalitis virus. Additionally, records of the Saudi Ministry of Health were reviewed. Read More

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Breast Augmentation with Microtextured Anatomical Implants in 653 Women: Indications and Risk of Rotation.

Plast Reconstr Surg 2021 May 10. Epub 2021 May 10.

From the Department of Plastic Surgery and Burns Treatment, Copenhagen University Hospital, Rigshospitalet; and Amalieklinikken.

Background: Anatomical implants provide a wide range of options in terms of implant dimensions for breast augmentation. Nevertheless, many surgeons choose not to use anatomical implants due to the risk of rotation malposition and because their advantages over round implants are not clearly defined.

Methods: A retrospective review of medical records was performed on all women who underwent breast augmentation or implant exchange with microtextured anatomical implants from 2012 to 2019 in a single private clinic. Read More

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The Use of Head-Worn Displays for Vital Sign Monitoring in Critical and Acute Care: Systematic Review.

JMIR Mhealth Uhealth 2021 May 11;9(5):e27165. Epub 2021 May 11.

School of Psychology, The University of Queensland, St Lucia, QLD, Australia.

Background: Continuous monitoring of patient vital signs may improve patient outcomes. Head-worn displays (HWDs) can provide hands-free access to continuous vital sign information of patients in critical and acute care contexts and thus may reduce instances of unrecognized patient deterioration.

Objective: The purpose of the study is to conduct a systematic review of the literature to evaluate clinical, surrogate, and process outcomes when clinicians use HWDs for continuous patient vital sign monitoring. Read More

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Infantile orbital abscess: clinical presentation, microbiological profile, and management outcomes.

Orbit 2021 May 11:1-7. Epub 2021 May 11.

Department of Orbit, Oculoplasty, Reconstructive and Aesthetics, Chennai, India.

: Orbital abscesses in children are not uncommon. Unless managed in a timely fashion, they can potentially lead to vision-threatening as well as life-threatening complications. The objective of this study is to report the clinical and microbiological profile and management outcomes in infants presenting with orbital abscesses. Read More

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Treatment of epilepsy for people with Alzheimer's disease.

Cochrane Database Syst Rev 2021 May 11;5:CD011922. Epub 2021 May 11.

Department of Geriatric Neurology, Chinese PLA General Hospital, Beijing, China.

Background: Any type of seizure can be observed in Alzheimer's disease. Antiepileptic drugs seem to prevent the recurrence of epileptic seizures in most people with Alzheimer's disease. There are pharmacological and non-pharmacological treatments for epilepsy in people with Alzheimer's disease, however there are no current systematic reviews to evaluate the efficacy and tolerability of these treatments. Read More

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Clinical Decision Support Systems in Orthodontics: A Narrative Review of Data Science Approaches.

Orthod Craniofac Res 2021 May 11. Epub 2021 May 11.

Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI, United States.

Advancements in technology and data collection generated immense amounts of information from various sources such as health records, clinical examination, imaging, medical devices, as well as experimental and biological data. Proper management and analysis of these data via high-end computing solutions, artificial intelligence and machine learning approaches can assist in extracting meaningful information that enhances population health and well-being. Furthermore, the extracted knowledge can provide new avenues for modern healthcare delivery via clinical decision support systems. Read More

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Gastrointestinal symptomatology, diagnosis, and treatment history in patients with underweight avoidant/restrictive food intake disorder and anorexia nervosa: Impact on weight restoration in a meal-based behavioral treatment program.

Int J Eat Disord 2021 May 11. Epub 2021 May 11.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Objective: Gastrointestinal (GI) concerns are often presumed to complicate nutritional rehabilitation for restrictive eating disorders, yet their relationship to weight restoration outcomes is unclear. This retrospective chart review examined GI history and weight-related discharge outcomes in primarily adult, underweight inpatients with anorexia nervosa (AN, N = 107) or avoidant/restrictive food intake disorder (ARFID, N = 22) treated in a meal-based, behavioral eating disorder program.

Method: Lifetime GI symptomatology, diagnoses, diagnostic tests, and procedures were abstracted from medical records. Read More

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Clinical characteristics and management differences for grade II and III spinal meningiomas.

J Neurooncol 2021 May 10. Epub 2021 May 10.

Mayo Clinic Neuro-Informatics Laboratory, Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.

Purpose: The majority of spinal meningiomas are grade I tumors, as defined by World Health Organization (WHO) classification making atypical (grade II) or anaplastic (grade III) tumors extremely rare lesions to encounter in clinical practice. Here, we present our institutional experience of management of grade II and III spinal meningiomas.

Methods: Following IRB approval, we queried all available institutional electronic medical records for patients undergoing surgical resection of pathology-proven spinal meningiomas, with further review of patients with grade II and III. Read More

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Genetic counseling and testing for Asian Americans: a systematic review.

Genet Med 2021 May 10. Epub 2021 May 10.

Department of Medicine, Stanford University, CA, USA.

Purpose: Asian Americans have been understudied in the literature on genetic and genomic services. The current study systematically identified, evaluated, and summarized findings from relevant qualitative and quantitative studies on genetic health care for Asian Americans.

Methods: A search of five databases (1990 to 2018) returned 8,522 unique records. Read More

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Interventions and strategies involving primary healthcare professionals to manage emergency department overcrowding: a scoping review.

BMJ Open 2021 May 10;11(5):e048613. Epub 2021 May 10.

George and Fay Yee Center for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada.

Objectives: To conduct a scoping review to identify and summarise the existing literature on interventions involving primary healthcare professionals to manage emergency department (ED) overcrowding.

Design: A scoping review.

Data Sources: A comprehensive database search of Medline (Ovid), EMBASE (Ovid), Cochrane Library (Wiley) and CINAHL (EBSCO) databases was conducted (inception until January 2020) using peer-reviewed search strategies, complemented by a search of grey literature sources. Read More

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Making every contact count: recognising obesity in paediatric and young adult cardiology.

Cardiol Young 2021 May 11:1-6. Epub 2021 May 11.

Department of Dietetics/SLT, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Introduction: With increased survival, children with CHD are reaching adulthood, however, obesity amongst this cohort is an emerging problem. Making every contact count encourages clinicians to utilise contact to elicit behaviour change. The aim of this work was to identify whether the body habitus of children classified as obese was addressed during a clinical review. Read More

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Risk of Vaccine-Preventable Infections in Swiss Adults with Inflammatory Bowel Disease.

Digestion 2021 May 10:1-9. Epub 2021 May 10.

Department of Pediatrics, Pediatric Infectious Disease Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.

Background: Patients with inflammatory bowel disease (IBD) have a higher risk of infection and are frequently not up to date with their immunizations.

Objectives: This study aims to review vaccination status and evaluate whether age, disease type, or treatment regimen could predict the absence of seroprotection against selected vaccine-preventable infection in adults with IBD.

Methods: Cross-sectional study using questionnaire, immunization records review, and assessment of tetanus-specific, varicella-specific, and measles-specific immunoglobulin G concentrations. Read More

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Artificial Intelligence for Adult Spinal Deformity: Current State and Future Directions.

Spine J 2021 May 7. Epub 2021 May 7.

Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.

As we experience a technological revolution unlike any other time in history, neurosurgery as a discipline is poised to undergo a dramatic transformation. As enormous amounts of data become digitized and more readily available, medical professionals approach a critical juncture with respect to how advanced computational techniques may be incorporated into clinical practices. Within neurosurgery, spinal disorders in particular, represent a complex and heterogeneous disease entity that can vary dramatically in its clinical presentation and how it may impact patients' lives. Read More

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Trends and concerns of potentially inappropriate medication use in patients with cardiovascular diseases.

Expert Opin Drug Saf 2021 May 10. Epub 2021 May 10.

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences.

IntroductionThe use of potentially inappropriate medications (PIM) is an alarming social risk factor in cardiovascular patients. PIM administration may result in iatrogenic disorders and adverse consequences may be attenuated by limiting PIM intake.Areas coveredThe goal of this review article is to discuss the trends, risks, and concerns regarding PIM administration with focus on cardiovascular patients. Read More

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The effect of cocoa-rich products on depression, anxiety, and mood: A systematic review and meta-analysis.

Crit Rev Food Sci Nutr 2021 May 10:1-13. Epub 2021 May 10.

Department of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, Catania, Italy.

In the popular imaginary, cocoa-derived products, like chocolate, represent a panacea for mood and affectivity. However, whether this is a myth or a fact has yet to be clarified. A systematic review and meta-analysis were conducted according to the PRISMA guidelines to investigate the effect of cocoa-derived food on depressive and anxiety symptoms, positive and negative affect. Read More

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Stigmatization of people with alcohol use disorders: An updated systematic review of population studies.

Alcohol Clin Exp Res 2021 May 10. Epub 2021 May 10.

Department of Psychiatry, Medical Faculty, University of Leipzig, Leipzig, Germany.

Background: We summarize research on the public stigmatization of persons with alcohol use disorder (AUD) in comparison with other mental health conditions and embed the results into a conceptual framework of the stigma process.

Methods: We conducted a systematic search using Embase, MEDLINE, PubMed and PsycINFO (via Ovid), and Web of Science for population-based studies on the public stigma in AUD and at least 1 other mental health condition, published between October 1, 2010 and December 20, 2020, thus including all studies published since the last systematic review on this topic. The study is registered with PROSPERO (registration number: CRD42020173054). Read More

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