339,527 results match your criteria review provide


Emergencies in freestanding ambulatory surgery centre.

Curr Opin Anaesthesiol 2021 Sep 24. Epub 2021 Sep 24.

Department of Anaesthesia & Intensive Care, Institution for Clinical Sciences, Karolinska Institutet at Danderyds University Hospital, Stockholm, Sweden.

Purpose Of Review: Ambulatory surgery is increasing, more procedures as well as more complex procedures are transferred to ambulatory surgery. Patients of all ages including elderly and more fragile are nowadays scheduled for ambulatory surgery. Enhanced recovery after surgery (ERAS) protocols are now developed for further facilitating readily recovery, ambulation, and discharge. Read More

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September 2021

Management of postoperative nausea and vomiting in adults: current controversies.

Curr Opin Anaesthesiol 2021 Sep 24. Epub 2021 Sep 24.

Department of Anesthesiology and Perioperative Medicine, Penn State Health, Hershey, Pennsylvania Department of Anesthesiology and Pain Management, University of Texas Southwestern, Dallas, Texas, USA.

Purpose Of Review: Postoperative nausea and vomiting (PONV) continue to plague the surgical patient population with an adverse impact on postoperative outcomes. The aim of this review is to critically assess current evidence for PONV management, including studies evaluating baseline risk reduction and antiemetic prophylaxis, to provide a pragmatic approach to prevention and treatment of PONV in routine clinical practice.

Recent Findings: Multiple recent reviews and guidelines have been published on this topic with some limitations. Read More

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September 2021

Cancer driver gene and non-coding RNA alterations as biomarkers of brain metastasis in lung cancer: A review of the literature.

Biomed Pharmacother 2021 Sep 21;143:112190. Epub 2021 Sep 21.

Zimagene Medical Genetics Laboratory, Avicenna St., Hamedan, Iran. Electronic address:

Brain metastasis (BM) is the most common event in patients with lung cancer. Despite multimodal treatments and advances in systemic therapies, development of BM remains one of the main factors associated with poor prognosis and mortality in patients with lung cancer. Therefore, better understanding of mechanisms involved in lung cancer brain metastasis (LCBM) is of great importance to suppress cancer cells and to improve the overall survival of patients. Read More

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September 2021

Regulation and functions of NLRP3 inflammasome in cardiac fibrosis: Current knowledge and clinical significance.

Biomed Pharmacother 2021 Sep 21;143:112219. Epub 2021 Sep 21.

Institute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine,Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China; Department of Cardiovascular Disease, ShuGuang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address:

Cardiac fibrosis can lead to heart failure, arrhythmia, and sudden cardiac death, representing one of the leading causes of death due to cardiovascular diseases. Cardiac fibrosis involves several multifactorial processes that cannot be effectively controlled by the available therapies. Therefore, current research has focused on the development of novel drugs that can be used to prevent cardiac fibrosis. Read More

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September 2021

Regulatory interplay between microRNAs and WNT pathway in glioma.

Biomed Pharmacother 2021 Sep 21;143:112187. Epub 2021 Sep 21.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Glioma is one of the most common neoplasms of the central nervous system with a poor survival. Due to the obstacles in treating this disease, a part of recent studies mainly focuses on identifying the underlying molecular mechanisms that contribute to its malignancy. Altering microRNAs (miRNAs) expression pattern has been identified obviously in many cancers. Read More

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September 2021

Nursing assistants and resident satisfaction in long-term care: A systematic review.

Geriatr Nurs 2021 Sep 21;42(6):1323-1331. Epub 2021 Sep 21.

College of Health and Public Service, University of North Texas, 410 S. Avenue C, Denton, TX 76201, United States.

Background: The number of nursing assistants (NAs) in the long-term care industry is on the rise, helping to service the needs of an increasingly aging population. Understanding influences on NAs service qualities and resident satisfaction is important to sustainable long-term care services. To date, the research evidence about NAs factors and resident satisfaction has not been synthesized. Read More

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September 2021

Development and implementation of venous thromboembolism stewardship across a hospital network.

Int J Med Inform 2021 Sep 14;155:104575. Epub 2021 Sep 14.

Concord Repatriation General Hospital, Department of Hematology, Sydney, Australia; Anzac Research Institute, Concord, Sydney, Australia; University of Sydney, Faculty of Medicine and Health, Sydney, Australia.

Background: Venous thromboembolism (VTE) is a leading cause of preventable death in hospital. Ensuring all hospitalized patients are assessed for VTE risk and given appropriate prophylaxis can reduce the burden of VTE on patients and the healthcare system. This is the first study to explore the effectiveness of a VTE stewardship program using electronic clinical decision support (eCDS) to provide oversight of hospital initiatives to prevent VTE. Read More

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September 2021

High intelligence may exacerbate paediatric inflammatory response to SARS-CoV-2 infection.

Med Hypotheses 2021 Sep 9;155:110677. Epub 2021 Sep 9.

Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

The body's innate and acquiredimmunesystems are critical in responses to a wide spectrum of assaults, including SARS-CoV-2 infection. We identify studies of autoimmunity to support our hypothesis that a high intelligence quotient (IQ) may put children at increased risk for severe COVID-19 sequelae; especially those whose viral load is high and/or who develop multisystem inflammatory syndrome in children (MIS-C). MIS-C is associated with a higher risk of COVID-19 morbidity and death, even in otherwise healthy children. Read More

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September 2021

Neuroscientific approaches to study prosociality.

Curr Opin Psychol 2021 Aug 31;44:38-43. Epub 2021 Aug 31.

Department of Social Neuroscience and Social Psychology, University of Bern, Switzerland. Electronic address:

Prosociality is a core feature of human functioning and has been a topic of interest across disciplinary boundaries for decades. In this review, we highlight different neuroscientific approaches that have enriched traditional psychological methods for studying prosocial behavior among individuals and groups. First, we outline findings from task-based neuroimaging studies that provide correlational evidence for the involvement of different neural mechanisms in prosocial behavior. Read More

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Prismatic 2.0 - Simulation software for scanning and high resolution transmission electron microscopy (STEM and HRTEM).

Micron 2021 Sep 10;151:103141. Epub 2021 Sep 10.

National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA, USA. Electronic address:

Scanning transmission electron microscopy (STEM), where a converged electron probe is scanned over a sample's surface and an imaging, diffraction, or spectroscopic signal is measured as a function of probe position, is an extremely powerful tool for materials characterization. The widespread adoption of hardware aberration correction, direct electron detectors, and computational imaging methods have made STEM one of the most important tools for atomic-resolution materials science. Many of these imaging methods rely on accurate imaging and diffraction simulations in order to interpret experimental results. Read More

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September 2021

Current understanding of autophagy in intrahepatic cholestasis of pregnancy.

Placenta 2021 Sep 20;115:53-59. Epub 2021 Sep 20.

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, 610041, China. Electronic address:

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease during pregnancy. Manifested with pruritus and elevation in bile acids, the etiology of ICP is still poorly understood. Although ICP is considered relatively benign for the mother, increased rates of adverse fetal outcomes including sudden fetal demise are possible devastating outcomes associated with ICP. Read More

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September 2021

Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls.

Brain Stimul 2021 Sep 21. Epub 2021 Sep 21.

Defitech Chair of Clinical Neuroengineering, Center for Neuroprosthetics (CNP) and Brain Mind Institute (BMI), Swiss Federal Institute of Technology Lausanne (EPFL), Geneva, Switzerland; Defitech Chair of Clinical Neuroengineering, Clinique Romande de Réadaptation, Center for Neuroprosthetics (CNP) and Brain Mind Institute (BMI), Swiss Federal Institute of Technology (EPFL Valais), Sion, Switzerland; Clinical Neuroscience, University of Geneva Medical School, Geneva, Switzerland. Electronic address:

Background: Noninvasive brain stimulation has been successfully applied to improve stroke-related impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous outcomes within and across studies. It has been proposed to develop and apply noninvasive brain stimulation in a patient-tailored, precision medicine-guided fashion to maximize response rates and effect magnitude. Read More

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September 2021

Machine-learning methods for ligand-protein molecular docking.

Drug Discov Today 2021 Sep 21. Epub 2021 Sep 21.

Université de Reims Champagne Ardenne, LICIIS - LRC CEA DIGIT, Reims, France. Electronic address:

Artificial intelligence (AI) is often presented as a new Industrial Revolution. Many domains use AI, including molecular simulation for drug discovery. In this review, we provide an overview of ligand-protein molecular docking and how machine learning (ML), especially deep learning (DL), a subset of ML, is transforming the field by tackling the associated challenges. Read More

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September 2021

Imaging in Osteoarthritis.

Osteoarthritis Cartilage 2021 Sep 21. Epub 2021 Sep 21.

Department of Radiology, New York University Grossmann School of Medicine, 550 1(st) Avenue, 3nd Floor, New York, NY 10016, USA.

Osteoarthritis (OA) is the most frequent form of arthritis with major implications on both individual and public health care levels. The field of joint imaging, and particularly magnetic resonance imaging (MRI), has evolved rapidly due to the application of technical advances to the field of clinical research. This narrative review will provide an introduction to the different aspects of OA imaging aimed at an audience of scientists, clinicians, students, industry employees, and others who are interested in OA but who do not necessarily focus on OA. Read More

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September 2021

Pharmacologic treatments in preclinical tinnitus models with special focus on Ginkgo biloba leaf extract EGb 761®.

Mol Cell Neurosci 2021 Sep 21:103669. Epub 2021 Sep 21.

Experimental Otolaryngology, ENT-Hospital, Head and Neck Surgery, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany. Electronic address:

Tinnitus is defined as the perception of sound in the absence of external acoustic stimuli. Frequent comorbidities or associated factors are depression, anxiety, concentration problems, insomnia, resignation, helplessness, headache, bruxism, or social isolation, just to name a few. Although many therapeutic approaches have already been tested with varying success, there still is no cure available for tinnitus. Read More

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September 2021

Effect of combined aerobic and resistance exercise on blood pressure in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials.

Exp Gerontol 2021 Sep 21:111560. Epub 2021 Sep 21.

School of Nursing, Jilin University, Changchun, Jilin 130021, China. Electronic address:

Objective: The purpose of this study is to evaluate the effects of combined aerobic and resistance exercise on blood pressure (BP) in postmenopausal women. The results of this study will provide an effective means for postmenopausal women to control BP and reduce the morbidity and mortality of cardiovascular disease (CVD).

Methods: Eligible studies were searched in five electronic databases until November 2020, and 11 randomized controlled trials that met the inclusion criteria were included in this systematic review and meta-analysis. Read More

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September 2021

Role of TRP ion channels in cerebral circulation and neurovascular communication.

Neurosci Lett 2021 Sep 21:136258. Epub 2021 Sep 21.

Robert M. Berne Cardiovascular Research Center, University of Virginia-School of Medicine, Charlottesville, Virginia, USA; Department of Molecular Physiology and Biological Physics, University of Virginia-School of Medicine, Charlottesville, Virginia, USA. Electronic address:

The dynamic regulation of blood flow is essential for meeting the high metabolic demands of the brain and maintaining brain function. Cerebral blood flow is regulated primarily by 1) the intrinsic mechanisms that determine vascular contractility and 2) signals from neurons and astrocytes that alter vascular contractility. Stimuli from neurons and astrocytes can also initiate a signaling cascade in the brain capillary endothelium to increase regional blood flow. Read More

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September 2021

Correlations between bone marrow radiation dose and hematologic toxicity in locally advanced cervical cancer patients receiving chemoradiation with cisplatin: a systematic review.

Radiother Oncol 2021 Sep 21. Epub 2021 Sep 21.

Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. Electronic address:

Patients with locally advanced cervical cancer (LACC) treated with chemoradiation often experience hematologic toxicity (HT), as chemoradiation can induce bone marrow (BM) suppression. Studies on the relationship between BM dosimetric parameters and clinically significant HT might provide relevant indices for developing BM-sparing (BMS) radiotherapy techniques. This systematic review studied the relationship between bone marrow dose and HT in LACC-patients treated with primary cisplatin-based chemoradiation. Read More

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September 2021

Catheter Lock Solutions for Reducing Catheter-Related Bloodstream Infections in Pediatric Patients: a network meta-analysis.

J Hosp Infect 2021 Sep 21. Epub 2021 Sep 21.

Department of Nosocomial Infection Prevention and Control, Beijing Friendship Hospital, Capital Medical University, Beijing, China. Electronic address:

Background: Different catheter lock solutions (CLSs) are used to reduce catheter-related bloodstream infection (CRBSI) for pediatric patients with central venous catheters (CVCs). But the most effective CLS is unknown.

Aim: To compare the effectiveness of different CLSs for the prevention of CRBSI in pediatric patients. Read More

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September 2021

The impact of daytime napping on athletic performance - a narrative review.

Scand J Med Sci Sports 2021 Sep 24. Epub 2021 Sep 24.

School of Physical Education and Sports Science, National and Kapodistrian University of Athens, Athens, Greece.

Mid-day napping has been recommended as a countermeasure against sleep debt and an effective method for recovery, regardless of nocturnal sleep duration. Herein, we summarize the available evidence regarding the influence of napping on exercise and cognitive performance as well as the effects of napping on athletes' perceptual responses prior to or during exercise. The existing studies investigating the influence of napping on athletic performance have revealed equivocal results. Read More

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September 2021

T-cell subsets in the skin and their role in inflammatory skin disorders.

Allergy 2021 Sep 24. Epub 2021 Sep 24.

Vrije Universiteit Brussel (VUB), Skin Immunology & Immune Tolerance (SKIN) Research Group, Laarbeeklaan 103, 1090, Brussels, Belgium.

T lymphocytes (T-cells) are major players of the adaptive immune response. Naive T-cells are primed in the presence of cytokines, leading to polarization into distinct T-cell subsets with specific functions. These subsets are classified based on their T-cell receptor profile, expression of transcription factors, surface cytokine and chemokine receptors, and their cytokine production, which together determine their specific function. Read More

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September 2021

Histologic Findings in Surgical Pathology Specimens From Individuals Taking Masculinizing Hormone Therapy for the Purpose of Gender Transition: A Systematic Scoping Review.

Arch Pathol Lab Med 2021 Sep 27. Epub 2021 Sep 27.

Department of Pathology, University of Utah, Salt Lake City (Schmidt).

Context.—: Transgender men and transmasculine persons experience a discordance between the female sex they were assigned at birth and their gender. They may choose to take hormone therapy and/or undergo surgery to masculinize the body. Read More

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September 2021

Risk prediction models for intensive care unit-acquired weakness in intensive care unit patients: A systematic review.

PLoS One 2021 24;16(9):e0257768. Epub 2021 Sep 24.

Department of Neurosurgery Intensive Care Unit, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.

Background And Objectives: Intensive care unit-acquired weakness (ICU-AW) commonly occurs among intensive care unit (ICU) patients and seriously affects the survival rate and long-term quality of life for patients. In this systematic review, we synthesized the findings of previous studies in order to analyze predictors of ICU-AW and evaluate the discrimination and validity of ICU-AW risk prediction models for ICU patients.

Methods: We searched seven databases published in English and Chinese language to identify studies regarding ICU-AW risk prediction models. Read More

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September 2021

Challenges and opportunities for assisted regional ecosystem adaptation: International experience and implications for adaptation research.

PLoS One 2021 24;16(9):e0257868. Epub 2021 Sep 24.

CSIRO, Brisbane, Australia.

Maintaining the functional integrity of ecosystems as climate pressures exceed natural rates of adaptation requires new knowledge and new approaches to governance and management. However, research into management interventions to assist regional ecosystem adaptation has generated both scientific and ethical debate. This paper reviews experience to date in order to identify the challenges and opportunities for assisted regional ecosystem adaptation and reflect on the implications for ongoing adaptation research. Read More

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September 2021

Sport Participation and Academic Performance in Children and Adolescents: A Systematic Review and Meta-analysis.

Med Sci Sports Exerc 2021 Sep 17. Epub 2021 Sep 17.

SPRINTER, Prevention Research Collaboration, Charles Perkins Centre, School of Public Health, Faculty of Medicine and Health, The University of Sydney, NSW, Australia Institute for Positive Psychology and Education, Australian Catholic University, NSW, Australia.

Introduction: Physical activity can improve academic performance; however, much less is known about the specific association between sport participation and academic performance and this evidence has not been synthesised. Our aim was to systematically review and combine via meta-analyses evidence of the association between sport participation and academic performance in children and adolescents.

Methods: We conducted searches of five electronic databases using sport and academic performance related terms. Read More

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September 2021

Through the Looking Glass: Insights into Visualization Pedagogy through Sentiment Analysis of Peer Review Text.

IEEE Comput Graph Appl 2021 Sep 24;PP. Epub 2021 Sep 24.

Peer review is a widely utilized feedback mechanism for engaging students. As a pedagogical method, it has been shown to improve educational outcomes, but we have found limited empirical measurement of peer review in visualization courses. In addition to increasing engagement, peer review provides diverse feedback and reinforces recently-learned course concepts through critical evaluation of others' work. Read More

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September 2021

: A Comprehensive Review of its Botany, Phytochemistry, Pharmacology, and Clinical Applications.

Am J Chin Med 2021 Sep 23:1-46. Epub 2021 Sep 23.

School of Pharmacy, Shaanxi University of Chinese Medicine, Xian Yang, Shaanxi 712046, P. R. China.

Rehd. et Wils () is a single species of genus, family, and it is a famous medicinal herb mostly growing in southern China, China Taiwan and Vietnam. is usually used for the treatments of hepatitis, Alzheimer's disease, renal transplantation, osteoporosis, and insomnia. Read More

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September 2021

Designing and development of epitope-based vaccines against .

Crit Rev Microbiol 2021 Sep 24:1-24. Epub 2021 Sep 24.

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

infection is the principal cause of serious diseases (e.g. gastric cancer and peptic ulcers). Read More

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September 2021

Association of Sagittal Spinopelvic Realignment with Correction in Lower Lumbar Lordosis after Surgical Treatment in Degenerative Lumbar Scoliosis.

Orthop Surg 2021 Sep 24. Epub 2021 Sep 24.

The Spine Surgery, The First Medical Center of the Chinese PLA General Hospital, Beijing, China.

Objective: To assess the effect that correction of lower lumbar lordosis (3L) has on global spine realignment due to the key role of 3L for scoliosis surgery in patients with degenerative lumbar scoliosis (DLS).

Methods: This study is a retrospective review performed between June 2018 and January 2020, including consecutive patients with DLS. Only patients age ≥ 45 years who had already undergone a selective root block operation and had the procedure of long-fusion extending to pelvis and posterior lumbar interbody fusion (PLIF) at lower lumbar spine (L -S ) were retained for analysis. Read More

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September 2021

Social environmental impact of COVID-19 and erectile dysfunction: an explorative review.

J Endocrinol Invest 2021 Sep 24. Epub 2021 Sep 24.

The Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK.

Background: To date, no attempt has been made to collate literature on the relationship between the social environmental impact of COVID-19 and erectile dysfunction. The aim of this explorative review was to assess and compare the prevalence of erectile dysfunction (ED) in male healthcare workers and males during the COVID-19 pandemic.

Methods: A systematic review of major databases from inception to February 2021 was conducted. Read More

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September 2021