139,133 results match your criteria review meta-analysis


Diagnostic accuracy of stroke volume variation for predicting fluid responsiveness in children undergoing cardiac surgery: a systematic review and meta-analysis.

Paediatr Anaesth 2021 Apr 21. Epub 2021 Apr 21.

Department of Intensive Care Unit, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizheng Street, Dong Lake District, Nanchang, 330000, Jiangxi Province, China.

Background: Stroke volume variation (SVV) appears to be reliable for predicting fluid responsiveness (FR) in adults and its predictive value in paediatric patients has been recently reported. However, its predictive value in children undergoing cardiac surgery is unclear.

Methods: A review and meta-analysis were performed on the diagnostic utility of SVV for predicting FR in children undergoing cardiac surgery. Read More

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[New aspects in Fournier's gangrene - a rapid review].

Aktuelle Urol 2021 Apr 21. Epub 2021 Apr 21.

Universitätsmedizin Rostock, Urologische Klinik und Poliklinik, Rostock.

Fournier's gangrene (FG) is a sporadic, life-threatening, necrotising infection affecting the perineum, perineal region and genitals. Published literature provides hints that the outcome of this disease has failed to improve in recent years. We have therefore performed a rapid evidence synthesis by searching the database MEDLINE. Read More

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Esthetic Outcomes of Implant-Supported Single Crowns Related to Abutment Type and Material: A Systematic Review.

Int J Prosthodont 2021 Mar-Apr;34(2):229-249

Purpose: To systematically review the influence of abutment material and configuration on the soft tissue esthetic outcomes of implant-supported single crowns (iSCs) after 3 years.

Materials And Methods: An electronic search on MEDLINE (PubMed) from January 2000 to July 2019 was conducted for clinical trials with no language restrictions. The focus question was: In partially edentulous patients with iSCs, does the abutment material (metal vs ceramic) or the configuration (standardized vs customized) have an effect on the soft tissue esthetic outcomes? Randomized controlled trials, controlled clinical trials, and prospective or retrospective case series with at least 10 patients and a minimum of 3 years of follow-up were included. Read More

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The psychometric properties of life-space mobility measures in community-dwelling older adults: a systematic review protocol.

JBI Evid Synth 2021 Apr 20. Epub 2021 Apr 20.

Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada.

Introduction: Mobility is one of the most important contributors to healthy aging and is traditionally measured through performance-based tests. Measuring life-space mobility is a holistic way to measure the spaces individuals visited over a period of time versus what they are physically able to do. However, before a measure of life-space mobility can be widely used in research and clinical settings it must have robust psychometric properties. Read More

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European Guidelines for Obesity Management in Adults with a Very Low-Calorie Ketogenic Diet: A Systematic Review and Meta-Analysis.

Obes Facts 2021 Apr 21:1-24. Epub 2021 Apr 21.

Dipartimento di Medicina, Università degli Studi di Padova, Padova, Italy.

Background: The very low-calorie ketogenic diet (VLCKD) has been recently proposed as an appealing nutritional strategy for obesity management. The VLCKD is characterized by a low carbohydrate content (<50 g/day), 1-1.5 g of protein/kg of ideal body weight, 15-30 g of fat/day, and a daily intake of about 500-800 calories. Read More

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Safety and Efficacy of Evacetrapib in Patients with Inadequately-controlled Hypercholesterolemia and High Cardiovascular Risk; A meta-analysis of Randomized Placebo-controlled Trials.

Prostaglandins Leukot Essent Fatty Acids 2021 Apr 12;168:102282. Epub 2021 Apr 12.

Medical Research Group of Egypt (MRGE), Cairo, Egypt; Department of Cardiology, National Heart Institute, Egypt.

Background: Low-density lipoprotein cholesterol (LDL-C) is causally related to cardiovascular disease. Inhibition of cholesteryl ester transfer protein with Evacetrapib may provide an additional treatment option for patients who do not reach their LDL-C goal with statins or patients who cannot tolerate statins. We aimed to evaluate the safety and efficacy of Evacetrapib in patients with inadequately-controlled hypercholesterolemia and high cardiovascular risk. Read More

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Radiofrequency ablation reduces pain for knee osteoarthritis: a meta-analysis of randomized controlled trials.

Int J Surg 2021 Apr 18:105951. Epub 2021 Apr 18.

Department of Trauma center, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, 225000, China. Electronic address:

Background: Currently, there is poor evidence on the effect of radiofrequency ablation (RFA) on pain and knee function in patients with knee osteoarthritis (OA). We performed a meta-analysis on randomized controlled trials (RCTs) to determine the effectiveness and safety of RFA on pain and knee function in individuals with knee OA.

Methods: PubMed, EMBASE, Web of Science, Cochrane, Ovid and MEDLINE were systematically searched (up to March 20, 2021) to obtain literature focusing on the impact of RFA on knee OA, using the following keywords and their synonyms: "radiofrequency ablation", "neurotomy", "knee" and "osteoarthritis". Read More

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Donor-specific elispot assay for predicting acute rejection and allograft function after kidney transplantation: a systematic review and meta-analysis.

Clin Biochem 2021 Apr 18. Epub 2021 Apr 18.

Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Erasmus MC Transplantation Institute, Rotterdam, the Netherlands. Electronic address:

Acute rejection remains an important problem after kidney transplantation. Enzyme-linked immunosorbent spot (ELISPOT) assay has been investigated extensively and has shown promising results as a predictor of allograft rejection. The objective of this study was to systematically review and analyze the predictive value of the donor-specific ELISPOT assay to identify recipients at risk for acute rejection. Read More

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Long-term Clinical Performance of Composite Resin or Ceramic Inlays, Onlays, and Overlays: A Systematic Review and Meta-analysis.

Oper Dent 2021 Jan;46(1):25-44

Clinical Relevance: Composite resin or ceramic inlays, onlays, and overlays can achieve high long-term survival and success rates.

Summary: Read More

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January 2021

Obesity management in primary care: systematic review exploring the influence of therapeutic alliance.

Fam Pract 2021 Apr 21. Epub 2021 Apr 21.

Vice President Research and Innovation office, University of Alberta, Edmonton, Canada.

Purpose: To identify the influence of the therapeutic alliance on the effectiveness of obesity interventions delivered in primary care.

Method: Systematic review of randomized controlled trials of primary care interventions for adult patients living with obesity. Comprehensive search strategy using the terms 'obesity', 'primary care' and 'intervention' of seven databases from 1 January 1998 to March 2018. Read More

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Efficacy of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) in late adolescents and adults: a systematic review and meta-analysis.

Eur J Orthod 2021 Apr 21. Epub 2021 Apr 21.

Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Oral and Maxillofacial Surgery, Nijmegen, The Netherlands.

Background: Miniscrew-Assisted Rapid Palatal Expansion (MARPE) is a non-surgical treatment for transverse maxillary deficiency. However, there is limited evidence concerning its efficacy.

Objectives: This systematic review aims to evaluate the efficacy of MARPE in late adolescents and adults by assessing success rate and skeletal and dental transverse maxillary expansion, as well as treatment duration, dental and periodontal side effects and soft tissue effects. Read More

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What proportion of people have a follow-up biopsy in randomized trials of treatments for non-alcoholic steatohepatitis?: A systematic review and meta-analysis.

PLoS One 2021 21;16(4):e0250385. Epub 2021 Apr 21.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.

Background And Aim: Trials of treatments for non-alcoholic steatohepatitis require endpoint assessment with liver biopsies. Previous large-scale trials have calculated their sample size expecting high retention but on average did not achieve this. We aimed to quantify the proportion of participants with a valid follow-up biopsy. Read More

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The proportion and effect of corticosteroid therapy in patients with COVID-19 infection: A systematic review and meta-analysis.

PLoS One 2021 21;16(4):e0249481. Epub 2021 Apr 21.

Department of Orthopedics, Honghui Hospital, Xi'anJiaotong University, Xi'an, PR China.

Objectives: Coronavirus disease 2019 (COVID-19) remains a global challenge. Corticosteroids constitute a group of anti-inflammatory and immunosuppressive drugs that are widely used in the treatment of COVID-19. Comprehensive reviews investigating the comparative proportion and efficacy of corticosteroid use are scarce. Read More

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The risk of mortality in patients with COVID-19 with pre-diagnosis use of NSAIDs: a meta-analysis.

Inflammopharmacology 2021 Apr 21. Epub 2021 Apr 21.

School of Applied Sciences, University of Huddersfield, Huddersfield, UK.

The notion that the use of non-steroidal anti-inflammatory drugs (NSAIDs) may lead to adverse outcomes upon acquisition of coronavirus disease 2019 (COVID-19) should be discredited with a review of the real-life evidence. We aimed to perform a meta-analysis to summarize the risk of mortality with the preadmission/pre-diagnosis use of NSAIDs in patients with COVID-19. A systematic literature search was performed to identify eligible studies in electronic databases. Read More

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Robotic bariatric surgery for the obesity: a systematic review and meta-analysis.

Surg Endosc 2021 Apr 21. Epub 2021 Apr 21.

Department of General Surgery, Lanzhou University Second Hospital, Lanzhou, 730000, China.

Objective: The aim of this meta-analysis is to evaluate the safety and efficacy of bariatric surgery (BS) in patients with obesity by robotic bariatric surgery (RBS) compared with laparoscopic bariatric surgery (LBS).

Methods: The study was performed through searching in Pubmed, Web of Science, Embase database and Cochrane Library until March 31, 2020 comparing RBS with LBS. Data were calculated on the following endpoints: operative time, length of hospital stay, reoperation within 30 days, overall complications, leak, stricture, pulmonary embolisms, estimated blood loss and mortality. Read More

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Axillary Pathologic Complete Response After Neoadjuvant Systemic Therapy by Breast Cancer Subtype in Patients With Initially Clinically Node-Positive Disease: A Systematic Review and Meta-analysis.

JAMA Surg 2021 Apr 21:e210891. Epub 2021 Apr 21.

Department of Surgery, Maastricht University Medical Center, Maastricht, the Netherlands.

Importance: An overview of rates of axillary pathologic complete response (pCR) for all breast cancer subtypes, both for patients with and without pathologically proven clinically node-positive disease, is lacking.

Objective: To provide pooled data of all studies in the neoadjuvant setting on axillary pCR rates for different breast cancer subtypes in patients with initially clinically node-positive disease.

Data Sources: The electronic databases Embase and PubMed were used to conduct a systematic literature search on July 16, 2020. Read More

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Effects of daily sedation interruption in intensive care unit patients undergoing mechanical ventilation: A meta-analysis of randomized controlled trials.

Int J Nurs Pract 2021 Apr 21:e12948. Epub 2021 Apr 21.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.

Aim: This study aimed to assess the effects of daily sedation interruption on the mechanical ventilation duration and relevant outcomes in mechanically ventilated patients in the intensive care unit (ICU).

Background: Previously, three meta-analyses on the association of daily sedation interruption with the mechanical ventilation duration have reported conflicting findings, and these did not support current guideline recommendations that daily sedation interruption can be routinely used in mechanically ventilated adult ICU patients.

Design: This was a systematic review and meta-analysis of randomized controlled studies. Read More

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The Prevalence of Incidental Mastoid Opacification and the Need for Intervention: A Meta-Analysis.

Laryngoscope 2021 Apr 21. Epub 2021 Apr 21.

Department of ENT, Gloucestershire Royal Hospital, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK.

Objectives/hypothesis: The increasing use of cross-sectional imaging has led to the predicament of incidental mastoid opacification (IMO). We investigated the prevalence of IMO and the clinical need for ENT assessment or intervention when identified.

Study Design: Systematic review and meta-analysis. Read More

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Paper Patching Versus Watchful Waiting of Traumatic Tympanic Membrane Perforations: A Meta-Analysis.

Laryngoscope 2021 Apr 21. Epub 2021 Apr 21.

Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Objectives/hypothesis: The aim of the study was to investigate the healing rates, the restoration of hearing, and the time for complete healing of paper patching versus watchful waiting for traumatic tympanic membrane perforations (TTMPs).

Study Design: Systematic review with meta analysis.

Methods: Publications were selected by a search on "PubMed," "Embase," and "Web of Science. Read More

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Erratum to: Response to Dr Shikata's letter: 'Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies'.

Jpn J Clin Oncol 2021 Apr 21. Epub 2021 Apr 21.

Division of Cancer Statistics Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.

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Effect of music therapy on improving sleep quality in older adults: A systematic review and meta-analysis.

J Am Geriatr Soc 2021 Apr 20. Epub 2021 Apr 20.

Department of Nursing, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Objectives: Poor sleep quality is a common issue among older adults; it can lead to a poor quality of life and impairments in cognitive function and physical health. This study aimed to conduct a systematic review and meta-analysis of the effect of listening to music on sleep quality in older adults.

Design: Systematic review and meta-analyses. Read More

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The effect of resistance training programs on lean body mass in postmenopausal and elderly women: a meta-analysis of observational studies.

Aging Clin Exp Res 2021 Apr 20. Epub 2021 Apr 20.

Sport and Exercise Sciences Research Unit, University of Palermo, Via Giovanni Pascoli 6, 90144, Palermo, Italy.

Aging and menopause are associated with morphological and functional changes which may lead to loss of muscle mass and therefore quality of life. Resistance training (RT) is an effective training mode to increase muscle mass. We reviewed the existing literature to identify studies implementing RT protocols and evaluating muscle hypertrophy exclusively in healthy, postmenopausal and elderly women. Read More

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Diverticular per oral endoscopic myotomy (DPOEM) for esophageal diverticular disease: a systematic review and meta-analysis.

Esophagus 2021 Apr 20. Epub 2021 Apr 20.

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

The traditional way to tackle Zenker's diverticulum (ZD) has been flexible endoscopic septum division (FESD). Recently, the concept of per oral endoscopic myotomy has been found useful for managing diverticular diseases of the esophagus and has been termed DPOEM. We performed a systematic review and meta-analysis to evaluate the efficacy and safety of D-POEM in diverticular disease of the esophagus and to compare it with FESD. Read More

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Reply to the letter to the editor regarding "Duration and choices of prophylactic anticonvulsants in subarachnoid hemorrhage: a systematic review and meta-analysis".

Authors:
Yuqi Chen Xin Hu

Neurosurg Rev 2021 Apr 21. Epub 2021 Apr 21.

Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu, Sichuan, 610041, People's Republic of China.

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The Effect of Antibiotic Restriction Programs on Prevalence of Antimicrobial Resistance: A Systematic Review and Meta-Analysis.

Open Forum Infect Dis 2021 Apr 13;8(4):ofab070. Epub 2021 Feb 13.

Department of Internal Medicine, Division of Infectious Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Background: In hospital settings, restriction of selected classes of antibiotics is usually believed to contribute to containment of resistance development. We performed a systematic review and meta-analysis to assess the effect of restricting the use of specific antibiotic classes on the prevalence of resistant bacterial pathogens.

Methods: We conducted a systematic literature search in Embase and PubMed/OVID MEDLINE. Read More

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Meta-Analysis of Correlations between Altmetric Attention Score and Citations in Health Sciences.

Biomed Res Int 2021 7;2021:6680764. Epub 2021 Apr 7.

Department of Endodontics, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Introduction: In recent years, several controversial reports of the correlation between altmetric score and citations have been published (range: -0.2 to 0.8). Read More

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The Association of Acute Kidney Injury With Disease Severity and Mortality in COVID-19: A Systematic Review and Meta-Analysis.

Cureus 2021 Mar 15;13(3):e13894. Epub 2021 Mar 15.

Internal Medicine, King Edward Medical University, Mayo Hospital, Lahore, PAK.

Background and objective The coronavirus disease 2019 (COVID-19) pandemic has become a global healthcare emergency. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, has a wide range of clinical manifestations ranging from subclinical infection to multi-organ failure. In addition to the respiratory system, COVID-19 also adversely affects the kidneys. Read More

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The global prevalence of essential tremor, with emphasis on age and sex: A meta-analysis.

J Glob Health 2021 Apr 10;11:04028. Epub 2021 Apr 10.

Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.

Background: Essential tremor (ET) is one of the most common neurological disorders that impairs quality of life and leads to disability and social handicap. It was estimated that approximate 0.9% of people worldwide were affected by ET. Read More

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Clinical Effects of Baduanjin Qigong Exercise on Cancer Patients: A Systematic Review and Meta-Analysis on Randomized Controlled Trials.

Evid Based Complement Alternat Med 2021 8;2021:6651238. Epub 2021 Apr 8.

Evidence-Based Medicine Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.

Objective: Baduanjin is a traditional Chinese Qigong exercise for health improvement. However, a few studies were examining the association between Baduanjin Qigong exercise and cancer patients. This study is conducted to explore the clinical effects of the Baduanjin Qigong exercise among cancer patients. Read More

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Xueshuantong Injection in Treating Deep Venous Thrombosis: A Systematic Review and Trial Sequential Analysis.

Evid Based Complement Alternat Med 2021 7;2021:6622925. Epub 2021 Apr 7.

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Aims: In recent years, the incidence of deep venous thrombosis (DVT) presents an increasing trend year by year. The current evidence regarding the efficacy and safety of Xueshuantong injection for DVT is controversial. This systematic review (SR) aimed to assess the efficacy and safety of Xueshuantong injection in the treatment of DVT systematically and provide an evidence-based reference for clinical treatment. Read More

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