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Global prevalence and associated risk factors of posttraumatic stress disorder during COVID-19 pandemic: A meta-analysis.

Int J Nurs Stud 2021 Nov 12;126:104136. Epub 2021 Nov 12.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Department of Nursing, Taipei Medical University-Shuang Ho Hospital, New Taipei, Taiwan; Center for Nursing and Healthcare Research in Clinical Practice Application, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Psychiatric Research Center, Taipei Medical University Hospital, Taipei, Taiwan. Electronic address:

Background: The COVID-19 pandemic has negatively impacted the psychological well-being of individuals and society. Previous studies conducted on coronavirus outbreaks including Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome pandemic found that posttraumatic stress disorder (PTSD), depression, and anxiety were the most common mental health problems and long-term consequences of these outbreaks. Currently, comprehensive and integrated information on the global prevalence of PTSD due to the COVID-19 pandemic is lacking. Read More

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November 2021

The potential for adverse effects in fish exposed to antidepressants in the aquatic environment.

Environ Sci Technol 2021 Dec 2. Epub 2021 Dec 2.

Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon EX4 4QD, U.K.

Antidepressants are one of the most commonly prescribed pharmaceutical classes for the treatment of psychiatric conditions. They act via modulation of brain monoaminergic signaling systems (predominantly serotonergic, adrenergic, dopaminergic) that show a high degree of structural conservation across diverse animal phyla. A reasonable assumption, therefore, is that exposed fish and other aquatic wildlife may be affected by antidepressants released into the natural environment. Read More

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December 2021

Supramolecular dynamic binary complexes with pH and salt-responsive properties for use in unconventional reservoirs.

PLoS One 2021 2;16(12):e0260786. Epub 2021 Dec 2.

Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas, United States of America.

Hydraulic fracturing of unconventional reservoirs has seen a boom in the last century, as a means to fulfill the growing energy demand in the world. The fracturing fluid used in the process plays a substantial role in determining the results. Hence, several research and development efforts have been geared towards developing more sustainable, efficient, and improved fracturing fluids. Read More

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December 2021

Comprehensive analysis of an immune infiltrate-related competitive endogenous RNA network reveals potential prognostic biomarkers for non-small cell lung cancer.

PLoS One 2021 2;16(12):e0260720. Epub 2021 Dec 2.

Department of Oncology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Globally, non-small cell lung cancer (NSCLC) is the most common malignancy and its prognosis remains poor because of the lack of reliable early diagnostic biomarkers. The competitive endogenous RNA (ceRNA) network plays an important role in the tumorigenesis and prognosis of NSCLC. Tumor immune microenvironment (TIME) is valuable for predicting the response to immunotherapy and determining the prognosis of NSCLC patients. Read More

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December 2021

How Do PROMIS Scores Correspond to Common Physical Abilities?

Clin Orthop Relat Res 2021 Nov 17. Epub 2021 Nov 17.

Department of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.

Background: The Patient-Report Outcomes Measurement Information System (PROMIS) is increasingly used as a general-purpose tool for measuring orthopaedic surgery outcomes. This set of questionnaires is efficient, precise, and correlates well with specialty-specific measures, but impactful implementation of patient-specific data, especially at the point of care, remains a challenge. Although clinicians may have substantial experience with established patient-reported outcome measures in their fields, PROMIS is relatively new, and the real-life meaning of PROMIS numerical summary scores may be unknown to many orthopaedic surgeons. Read More

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November 2021

Distribution of copy number variation in Chinese goats and its associations with milk production traits.

Anim Biotechnol 2021 Dec 2:1-6. Epub 2021 Dec 2.

College of Animal Science and Technology, Northwest A & F University, Shaanxi Key Laboratory of Molecular Biology for Agriculture, Yangling, Shaanxi, China.

Goat is an important sector for meat and dairy products. Diacylglycerol O-acyltransferase 1 (), which is a key gene in milk production, has been recently detected to overlap with a novel copy number variation (CNV) in goats. CNVs could be genetic markers providing new insights into the genetic basis of phenotypic variation. Read More

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December 2021

Decline of virtual water inequality in China's inter-provincial trade: An environmental economic trade-off analysis.

Sci Total Environ 2022 Feb 24;806(Pt 2):150524. Epub 2021 Sep 24.

School of Atmospheric Sciences, Nanjing University, Nanjing 210023, China. Electronic address:

The trade-off between economic growth and environmental conservation is a significant factor in national environmental management. Previous studies have revealed that there are substantial water resources embodied in the inter-regional trade of China, but there is a scarcity of studies analyzing the cost-benefit inequality in trade, which should be considered when developing water resource allocation and conservation policies. The aim of the present study was to fill the gap in existing research by constructing a novel virtual water inequality index based on the net transfers of virtual water and value added between trading provinces. Read More

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February 2022

Genome-wide association analysis of chickpea germplasms differing for salinity tolerance based on DArTseq markers.

PLoS One 2021 1;16(12):e0260709. Epub 2021 Dec 1.

Department of Biodiversity and Crop Improvement, International Center for Agriculture Research in the Dry Areas, Agricultural Research Centre, Giza, Egypt.

Soil salinity is significant abiotic stress that severely limits global crop production. Chickpea (Cicer arietinum L.) is an important grain legume that plays a substantial role in nutritional food security, especially in the developing world. Read More

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December 2021

Electron Delocalization in Spectroelectrochemically and Computationally Characterized [Pt{(-BrCF)NCH═C(Cl)NEt}Cl(py)] Formed by Electrochemical Oxidation of [Pt{(-BrCF)NCH═C(Cl)NEt}Cl(py)].

Inorg Chem 2021 Dec 1. Epub 2021 Dec 1.

School of Chemistry, Monash University, Clayton, VIC 3800, Australia.

[Pt{(-BrCF)NCH═C(Cl)NEt}Cl(py)] () is the product of the hydrogen peroxide oxidation of the Pt anticancer agent [Pt{(-BrCF)NCHCHNEt}Cl(py)] (). Insights into electron delocalization and bonding in [Pt{(-BrCF)NCH═C(Cl)NEt}Cl(py)] () obtained by electrochemical oxidation of have been gained by spectroscopic and computational studies. The process is chemically and electrochemically reversible on the short time scale of voltammetry in dichloromethane (0. Read More

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December 2021

Time-series transcriptomic analysis of bronchoalveolar lavage cells from virulent and low virulent PRRSV-1-infected piglets.

J Virol 2021 Dec 1:JVI0114021. Epub 2021 Dec 1.

Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, 14014, Córdoba, Spain.

Porcine reproductive and respiratory syndrome virus (PRRSV) has evolved to escape the immune surveillance for a survival advantage leading to a strong modulation of host's immune responses and favoring secondary bacterial infections. However, limited data are available on how the immunological and transcriptional responses elicited by virulent and low virulent PRRSV-1 strains are comparable and how are them conserved along the infection. To explore the kinetic transcriptional signature associated with the modulation of host immune response at lung level a time-series transcriptomic analysis was performed in bronchoalveolar lavage cells upon experimental infection with two PRRSV-1 strains of different virulence, virulent subtype 3 Lena strain or the low virulent subtype 1 3249 strain. Read More

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December 2021

The MADS-domain factor AGAMOUS-Like18 promotes somatic embryogenesis.

Plant Physiol 2021 Nov 25. Epub 2021 Nov 25.

Dept. of Plant and Soil Sciences, 1405 Veterans Dr., Plant Science Building, University of Kentucky, Lexington, KY 40546-0312 USA.

AGAMOUS-Like 18 (AGL18) is a MADS domain transcription factor that is structurally related to AGAMOUS-Like 15 (AGL15). Here we show that, like AGL15, AGL18 can promote somatic embryogenesis (SE) when ectopically expressed in Arabidopsis (Arabidopsis thaliana). Based on loss-of-function mutants, AGL15 and AGL18 have redundant functions in developmental processes such as SE. Read More

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November 2021

Hsa_circ_0007059 sponges miR-421 to repress cell growth and stemness in hepatocellular carcinoma by the PTEN-AKT/mTOR pathway.

Pathol Res Pract 2021 Nov 19;229:153692. Epub 2021 Nov 19.

Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China. Electronic address:

Background: Hepatocellular carcinoma (HCC) is a substantial health concern worldwide. Increasing studies have suggested that circle RNAs (circRNAs) function as new regulators in HCC progression. The present work explored the role of hsa_circ_0007059 (circ_0007059) in the developing process of hepatocarcinogenesis. Read More

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November 2021

Management of late adverse effects after chemoradiation for anal cancer.

Acta Oncol 2021 Nov 30:1-14. Epub 2021 Nov 30.

Danish Cancer Society, National Research Centre for Survivorship and Late Adverse Effects following Pelvic Organ Cancer, Department of Surgery, Aarhus University Hospital, Aalborg, Denmark.

Background And Purpose: Significant improvements in the treatment of anal cancer have produced a growing population of anal cancer survivors. These patients often experience late adverse effects related to their treatment. Research has revealed substantial unmet needs because of long-term symptoms and functional impairments after treatment that may negatively affect health-related quality of life. Read More

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November 2021

Policies and practices in the field of laboratory hematology in Croatia - a current overview and call for improvement.

Clin Chem Lab Med 2021 Jan 1. Epub 2021 Jan 1.

Working Group for Laboratory Hematology of the Croatian Society of Medical Biochemistry and Laboratory Medicine, Zagreb, Croatia.

Objectives: In 2019 The Croatian Working Group for Laboratory Hematology, on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine, wanted to explore the background in field of laboratory hematology routine practice among Croatian laboratories in order to develop future strategies for producing national recommendations, if needed.

Methods: During April and May 2019, a comprehensive survey covering all main parts of the total testing process within the field of laboratory hematology among Croatian medical laboratories was conducted. The survey comprised 49 inquiries. Read More

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January 2021

Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine.

J Korean Med Sci 2021 Nov 29;36(46):e311. Epub 2021 Nov 29.

Department of Pediatrics, Myongji Hospital, Goyang, Korea.

Background: ChAdOx1 and BNT162b2 vaccines are currently commonly used against coronavirus disease 2019 worldwide. Our study was designed to determine the serostatus and relative levels of anti-S and neutralizing antibodies in patients who were administered either ChAdOx1 or BNT162b2 vaccine. In addition, we investigated whether the antibody response to each vaccine differed according to sex and age. Read More

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November 2021

Recombinant Bacillus subtilis flagellin Hag is a potent immunostimulant with reduced proinflammatory properties compared to Salmonella enterica serovar Typhimurium FljB.

Vaccine 2021 Nov 26. Epub 2021 Nov 26.

Department of Biological Sciences, Université du Québec à Montréal, Montréal, Canada; The Swine and Poultry Infectious Diseases Research Centre (CRIPA), Saint-Hyacinthe, Canada. Electronic address:

Flagellin constitutes a potential adjuvant for vaccines owing to its robust immunostimulatory properties. However, clinical trials have revealed that flagellin derived from Salmonella enterica serovar Typhimurium induces high levels of proinflammatory markers and substantial adverse effects. The flagellin from Bacillus subtilis, Hag, shares high sequence homology with Salmonella FljB within the D0 and D1 domains responsible for TLR5 engagement, while the D2 and D3 domains associated with an off-target immune response are absent. Read More

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November 2021

The coronavirus disease 2019 (COVID-19) vaccination psychological antecedent assessment using the Arabic 5c validated tool: An online survey in 13 Arab countries.

PLoS One 2021 29;16(11):e0260321. Epub 2021 Nov 29.

Tropical Health Department, High Institute of Public Health, Alexandria University, Alexandria, Egypt.

Background: Following the emergency approval of the coronavirus disease 2019 (COVID-19) vaccines, research into its vaccination hesitancy saw a substantial increase. However, the psychological behaviors associated with this hesitancy are still not completely understood. This study assessed the psychological antecedents associated with COVID-19 vaccination in the Arab population. Read More

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November 2021

Characteristics of maternal depression and children's functioning: A meta-analytic review.

J Fam Psychol 2021 Nov 29. Epub 2021 Nov 29.

Department of Psychology and Human Development.

Maternal depression is associated with cognitive, emotional, and behavioral problems in offspring, but the substantial heterogeneity of depression precludes a full understanding of these associations. Variation in course of depression, characterized by severity or chronicity, may be related differentially to children's development. The current meta-analytic review examined the relations of these characteristics of maternal depression to children's developmental outcomes. Read More

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November 2021

Cast Away in the Adriatic: Low Degree of Parallel Genetic Differentiation in Three-Spined Sticklebacks.

Mol Ecol 2021 Nov 29. Epub 2021 Nov 29.

Ecological Genetics Research Unit, Organismal and Evolutionary Biology Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, FI-00014, Finland.

The three-spined stickleback (Gasterosteus aculeatus) has repeatedly and independently adapted to freshwater habitats from standing genetic variation (SGV) following colonisation from the sea. However, in the Mediterranean Sea G. aculeatus is believed to have gone extinct, thus the spread of locally adapted alleles between different freshwater populations via the sea since then has been highly unlikely. Read More

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November 2021

How to Get Better: Taking Notes Mediates the Effect of a Video Tutorial on Number Series.

J Intell 2021 Nov 18;9(4). Epub 2021 Nov 18.

Department of Educational Science, Saarland University, Campus A 5 4, D-66123 Saarbrücken, Germany.

In recent studies, test-score increases have been shown in rule-based intelligence test tasks, such as number series, after watching a corresponding video tutorial. An open question remains regarding the mechanisms involved. Specifically, taking notes to describe the relations between numbers might be linked to test scores, and is hypothesized to mediate the effect of a number series video tutorial on number series test scores. Read More

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November 2021

COVID-19 Lockdown-Related Changes in Mood, Health and Academic Functioning.

Eur J Investig Health Psychol Educ 2021 Nov 18;11(4):1440-1461. Epub 2021 Nov 18.

Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands.

The COVID-19 pandemic lockdowns were accompanied by an abrupt transition from face-to-face education to online education. The aim of this study was to evaluate the impact of the COVID-19 pandemic on academic functioning and mood in Dutch pharmacy students and PhD candidates. A total of = 341 participants completed an online survey including questions on mood and academic functioning, assessed retrospectively for before and during the COVID-19 pandemic. Read More

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November 2021

The Hubei Memory and Aging Cohort Study: Study Design, Baseline Characteristics, and Prevalence of Cognitive Impairments.

J Alzheimers Dis 2021 Nov 23. Epub 2021 Nov 23.

Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.

Background: Despite the improved access to health services in China, inadequate diagnosis and management of dementia are common issues, especially in rural regions.

Objective: The Hubei Memory & Aging Cohort Study was designed as a prospective study in Central China to determine the prevalence, incidence, and risk factors for dementia and mild cognitive impairment (MCI) among urban and rural older adults.

Methods: From 2018-2020, participants aged ≥65 years were screened, and data regarding their life behaviors, families, socio-economic status, physical and mental health, social and psychological factors, and cognition were collected. Read More

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November 2021

Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT.

Health Technol Assess 2021 Nov;25(69):1-62

Division of Psychiatry, University College London, London, UK.

Background: There has been a steady increase in the number of primary care patients receiving long-term maintenance antidepressant treatment, despite limited evidence of a benefit of this treatment beyond 8 months.

Objective: The ANTidepressants to prevent reLapse in dEpRession (ANTLER) trial investigated the clinical effectiveness and cost-effectiveness of antidepressant medication in preventing relapse in UK primary care.

Design: This was a Phase IV, double-blind, pragmatic, multisite, individually randomised parallel-group controlled trial, with follow-up at 6, 12, 26, 39 and 52 weeks. Read More

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November 2021

Capacity of nurses working in long-term care: A systematic review qualitative synthesis.

J Clin Nurs 2021 Nov 28. Epub 2021 Nov 28.

School of Nursing, Midwifery & Paramedicine, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.

Background: The United Nations calculates there were 703 million adults 65 years and older globally as of 2019 with this number projected to double by 2050. A significant number of older adults live with comorbid health conditions, making the role of a nurse in long-term care (LTC) complex. Our objective was to identify the challenges, facilitators, workload, professional development and clinical environment issues that influence nurses and nursing students to seek work and continue to work in LTC settings. Read More

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November 2021

Long-term effects of early antiretroviral initiation on HIV reservoir markers: a longitudinal analysis of the MERLIN clinical study.

Lancet Microbe 2021 May 23;2(5):e198-e209. Epub 2021 Mar 23.

(M Massanella PhD, N Chomont PhD); (M Massanella, A Pagliuzza MSc, N Chomont); (R A Bender Ignacio MD, S Dasgupta PhD, D Pinto-Santini PhD, T Gilada MD, Prof A Duerr MD); (R A B Ignacio, Prof A Duerr); (J R Lama MD, R Alfaro MS, J Rios MS, C Ganoza MD).

Background: Early antiretroviral therapy (ART) initiation (ie, within 3 months of infection) limits establishment of the HIV reservoir. However, the effect of early ART initiation on the long-term dynamics of the pool of infected cells remains unclear.

Methods: In this longitudinal analysis, we included cisgender men who have sex with men (MSM) and transgender women (aged 18-54 years) at high risk for HIV infection, enrolled in the ongoing longitudinal MERLIN study in Peru between Oct 28, 2014, and Nov 8, 2018. Read More

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Pain, numbness, or both? Distinguishing the longitudinal course and predictors of positive, painful neuropathic features vs numbness after breast cancer surgery.

Pain Rep 2021 Nov-Dec;6(4):e976. Epub 2021 Nov 22.

Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

Introduction: Both positive (burning, stabbing, and allodynia) and negative (numbness) neuropathic symptoms may arise after surgery but likely contribute differently to patients' postoperative pain experience. Numbness has been identified as divergent from positive neuropathic symptoms and therefore excluded from some neuropathic assessment tools (Neuropathic Pain Scale for PostSurgical patients [NeuPPS]).

Objectives: In this prospective longitudinal study of patients undergoing breast surgery, we aimed to delineate the time course of numbness and its coincidence with NeuPPS and to contrast the association of surgical, psychosocial, and psychophysical predictors with the development of negative vs positive neuropathic symptoms. Read More

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November 2021

How do patients with chronic illnesses respond to a public health crisis? Evidence from diabetic patients in Japan during the COVID-19 pandemic.

SSM Popul Health 2021 Dec 15;16:100961. Epub 2021 Nov 15.

Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

How do people change their healthcare behavior when a public health crisis occurs? Within a year of its emergence, coronavirus disease 2019 (COVID-19) has gradually infiltrated our lives and altered our lifestyles, including our healthcare behaviors. In Japan, which faces China across the East China Sea and accepted 924,800 Chinese tourists in January 2020, the emergence and spread of COVID-19 provides a unique opportunity to study people's reactions and adaptations to a pandemic. Patients with chronic illnesses who require regular doctor visits are particularly affected by such crises. Read More

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December 2021

Loeffler's syndrome in a child: A rare radiological and histopathological diagnosis.

Radiol Case Rep 2022 Jan 18;17(1):245-249. Epub 2021 Nov 18.

Department of Histology, Embryology, Pathology and Forensic Medicine, University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen street, Hue city, 530000, Viet Nam.

Loffler syndrome is an uncommon, self-limited, benign pulmonary eosinophilia that usually lasts less than a month. Abnormal chest radiography occurs in 95% of patients; however, computed tomography findings are not well described. We present clinical features, radiological, and pathological findings of Loeffler's syndrome with secondary bacterial pneumonia in a child. Read More

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January 2022

Insight into the thermal kinetics and thermodynamics of sulfuric acid plant sludge for efficient recovery of sulfur.

Waste Manag 2021 Nov 25. Epub 2021 Nov 25.

Department of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India. Electronic address:

The disposal and management of sulfur-rich sludges (SRS) are challenging issues for the industries due to their adverse environmental impact. The present study reports the detailed characterizations and assessment of the thermo-kinetics of sludge generated from the sulfuric acid plant. In addition, the sulfur was retrieved with the help of the evaporation-condensation method. Read More

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November 2021