144 results match your criteria revealed intra-group

Evaluation of ICCMS versus CAMBRA Caries Risk Assessment Models Acquisition on Treatment Plan in Young Adult Population: A Randomized Clinical Trial.

Clin Cosmet Investig Dent 2021 15;13:293-304. Epub 2021 Jul 15.

Conservative Dentistry Department, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Purpose: To evaluate the difference between ICCMS and CAMBRA models on treatment plan of young adults.

Settings And Design: A total of 104 young adult patients were randomly divided into two groups, either ICCMS or CAMBRA.

Patients And Methods: Patients were examined according to the criteria of the ICDAS-II and caries risk was analyzed according to CAMBRA and divided into two equal groups according to treatment protocol. Read More

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Vitamin D supplementation reduces serum markers of bone resorption and muscle damage in female basketball players with vitamin D inadequacy.

Eur J Sport Sci 2021 Jul 9:1-20. Epub 2021 Jul 9.

Faculty of Sport and Physical Education, University of Niš, Niš, Serbia.

This study aimed to investigate the effect of vitamin D supplementation at a dose of 4,000 IU/day for 6 weeks on serum levels of: 25-hydroxyvitamin D [25(OH)D], bone turnover [osteocalcin and carboxy-terminal telopeptides of crosslinks of type I collagen (CTx-I)], and muscle damage [lactate dehydrogenase (LDH) and creatine kinase (CK)] in middle adolescent (15-18 years) and late-adolescent to early adulthood (19-30 years) female basketball players with inadequate vitamin D status. Participants (N=24) were randomly assigned in a double-blind manner into a vitamin D or placebo group. Data were analyzed using separate 2 × 2x2 mixed ANOVAs with one within-subjects factor (time) and two between-subjects factors (condition and age). Read More

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Effect of ultrasonic scaling with adjunctive photodynamic therapy on the treatment of gingival inflammation among diabetic patients undergoing fixed orthodontic treatment.

Photodiagnosis Photodyn Ther 2021 May 27;35:102360. Epub 2021 May 27.

Department of Pediatric and Orthodontic Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia.

Background: The aim of the present clinical trial was to evaluate the effect of methylene blue-mediated antimicrobial photodynamic therapy (aPDT) on the gingival and immunological parameters in diabetic adolescent patients undergoing fixed orthodontic treatment.

Methods: The selected 40 participants were randomized equally into two groups; Group I (ultrasonic scaling + oral hygiene instructions) and Group II (ultrasonic scaling/oral hygiene instructions + aPDT). Serum HbA1c levels was assessed for all the participants at chairside. Read More

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Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data.

BMC Genomics 2021 May 3;22(1):322. Epub 2021 May 3.

Molecular Research Center, Inc., Cincinnati, USA.

Background: RNA sequencing analysis focus on the detection of differential gene expression changes that meet a two-fold minimum change between groups. The variability present in RNA sequencing data may obscure the detection of valuable information when specific genes within certain samples display large expression variability. This paper develops methods that apply variance and dispersion estimates to intra-group data to identify genes with expression values that diverge from the group envelope. Read More

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Psychosocial Well-Being, Mental Health, and Available Supports in an Arab Enclave: Exploring Outcomes for Foreign-Born and U.S.-Born Adolescents.

Front Psychiatry 2021 8;12:632031. Epub 2021 Apr 8.

Brown School at Washington University in St. Louis, St. Louis, MO, United States.

Few studies have assessed the impact of displacement, resettlement, and discrimination on well-being outcomes for adolescent refugees resettled within the U.S. Conducted in three charter schools in the intergenerational Arab enclave of the Detroit Metropolitan Area, this mixed-methods study assessed the mental health and psychosocial support for both U. Read More

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Efficacy of propolis in remineralising artificially induced demineralisation of human enamel - An in-vitro study.

J Taibah Univ Med Sci 2021 Apr 14;16(2):283-287. Epub 2020 Dec 14.

Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, KSA.

Objective: In this study, we aimed to analyse the enamel-remineralisation potential of propolis.

Materials And Methods: Twenty enamel blocks (N = 20) were randomly divided into two groups (n = 10). In group 1 (control), enamel blocks were brushed with artificial saliva (AS). Read More

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[Predictive value of combination of MRI tumor regression grade and apparent diffusion coefficient for pathological complete remission after neoadjuvant treatment of locally advanced rectal cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2021 Apr;24(4):359-365

Medical Imaging Center, the First Affiliate Hospital, Kunming Medical University, Kunming 650032, China.

Pelvic high-resolution magnetic resonance imaging (MRI) has now become a standard method for evaluating the efficacy of neoadjuvant treatment for locally advanced rectal cancer (LARC). However, this traditional morphological qualitative assessment method based on T2-weighted imaging (T2WI) is not effective in predicting pathological complete remission (pCR). The purpose of this study is to investigate whether combining the magnetic resonance tumor regression grade (mrTRG) with apparent diffusion coefficient (ADC) can improve diagnostic value for pCR after preoperative neoadjuvant chemoradiotherapy (nCRT) of LARC. Read More

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The effects of nano-curcumin supplementation on Th2/tregulatory axis in migraine patients: a randomized, double-blind, placebo-controlled trial.

Int J Neurosci 2021 Mar 16:1-7. Epub 2021 Mar 16.

Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.

Aim: In the present study we aimed to investigate the effects of nano-curcumin supplementation on gene expression and serum levels of IL-4 and TGF-β in migraine patients.

Methods: Forty participants with episodic migraine were randomly allocated to receive 80 mg nano-curcumin ( = 20) or placebo ( = 20) in a randomized double-blind clinical trial for two months. At the beginning and the end of the study, the interictal serum levels and gene expression of IL-4 and TGF-β in peripheral blood mononuclear cells (PBMCs) isolated from migraine patients were measured, using ELISA and real-time PCR methods, respectively. Read More

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Three-dimensional morphological and positional analysis of the temporomandibular joint in adults with posterior crossbite: A cross-sectional comparative study.

J Oral Rehabil 2021 Jun 2;48(6):666-677. Epub 2021 Mar 2.

Department of Orthodontics, Hubei-MOST KLOS & KLOBM, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

Objectives: The purpose of this study was to three-dimensionally (3D) evaluate the morphological and positional features of the temporomandibular joint (TMJ) in adults with unilateral and bilateral posterior crossbite compared with aligned control subjects.

Materials And Methods: This cross-sectional comparative study analysed cone beam computed tomography (CBCT) images of 90 adult subjects' divided into three equal groups: bilateral posterior crossbite (BCG), unilateral posterior crossbite (UCG) and control group (CG). 3D measurements of the TMJ included the following: (a) position, angulation and inclination of the mandibular condyles; (b) centralisation of the condyles in their respective mandibular fossae; and (c) volumetric measurements of the TMJ spaces. Read More

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Influence of Lignocaine Hydrochloride with Adrenaline on Free Active Chlorine Content of Sodium Hypochlorite Solution Admixed in Various Proportions.

Eur Endod J 2021 Apr 26;6(1):117-121. Epub 2021 Jan 26.

Department of Conservative Dentistry and Endodontics, SRM Dental College, Ramapuram, Tamil Nadu, India.

Objective: Local anaesthetic solution that is commonly employed for supplemental intrapulpal injection (IPI) may routinely come in contact with subsequently used sodium hypochlorite (NaOCl) during endodontic treatment of symptomatic irreversible pulpitis cases. This in vitro study investigated the available free active chlorine (FAC) content of 3% NaOCl after mixing with 2% lignocaine hydrochloride with adrenaline (LA) solution in three different proportions using iodometric titration analysis.

Methods: Aliquots of 3% NaOCl (control) in different measures (30 mL, 27 mL, 21 mL and 15 mL) served as the effective concentrate of various proportions of NaOCl admixed with the test solutions, i. Read More

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Effects of smoking on the gingival crevicular fluid levels of interleukin-17A, interleukin-17E, and oxidative stress following periodontal treatment process.

J Periodontal Res 2021 Apr 17;56(2):388-396. Epub 2021 Jan 17.

Department of Biochemistry, Ondokuz Mayis University Medical Faculty, Samsun, Turkey.

Objective And Background: How smoking affects periodontal inflammation and healing still needs to be revealed with all its mechanisms. In this study, the gingival crevicular fluid (GCF) levels of: (a) interleukin-17A (IL-17A) and interleukin-17E(IL-17E) with their ratios and (b) oxidative stress by means of total oxidative stress (TOS), total anti-oxidant capacity (TAOC), and their ratios as the oxidative stress index (OSI) were evaluated and compared for smoking and non-smoking periodontitis patients after a periodontitis management process including both the non-surgical and surgical treatments.

Materials And Methods: Fifteen smoker and 15 non-smoker generalized periodontitis patients as 2 distinct groups participated in the study. Read More

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Hydrophilic titanium surface modulates early stages of osseointegration in osteoporosis.

J Periodontal Res 2021 Apr 26;56(2):351-362. Epub 2020 Dec 26.

Department of Biological and Material Sciences & Prosthodontics, University of Michigan School of Dentistry, Ann Arbor, MI, USA.

Objective: Using a mouse osteoporotic model, this study aimed to determine the influence of hydrophilic titanium surfaces on gene expression and bone formation during the osseointegration process.

Background: Based on the previous evidence, it is plausible to assume that osteoporotic bone has a different potential of bone healing. Therefore, implant surface modification study that aims at enhancing bone formation to further improve short- and long-term clinical outcomes in osteoporosis is necessary. Read More

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Wide distribution of Phycisphaera-like planctomycetes from WD2101 soil group in peatlands and genome analysis of the first cultivated representative.

Environ Microbiol 2021 Mar 22;23(3):1510-1526. Epub 2020 Dec 22.

Institute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia.

Phycisphaera-like WD2101 'soil group' is one of the as-yet-uncultivated phylogenetic clades within the phylum Planctomycetes. Members of this clade are commonly detected in various terrestrial habitats. This study shows that WD2101 represented one of the major planctomycete groups in 10 boreal peatlands, comprising up to 76% and 36% of all Planctomycetes-affiliated 16S rRNA gene reads in raised bogs and eutrophic fens respectively. Read More

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BDCA1 cDC2s, BDCA2 pDCs and BDCA3 cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients.

Clin Transl Immunology 2020 24;9(11):e1190. Epub 2020 Nov 24.

Institute for Advanced Biosciences, Immunobiology and Immunotherapy in Chronic Diseases Inserm U 1209 CNRS UMR 5309 Université Grenoble Alpes Grenoble 38000 France.

Objectives: Dendritic cells play a pivotal but still enigmatic role in the control of tumor development. Composed of specialised subsets (cDC1s, cDC2s, pDCs), DCs are critical in triggering and shaping antitumor immune responses. Yet, tumors exploit plasticity of DCs to subvert their functions and escape from immune control. Read More

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November 2020

Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach.

Int J Mol Sci 2020 Nov 12;21(22). Epub 2020 Nov 12.

Graduate Institute of Toxicology, National Taiwan University College of Medicine, Taipei 100233, Taiwan.

Vascular calcification (VC) is a critical contributor to the rising cardiovascular risk among at-risk populations such as those with diabetes or renal failure. The pathogenesis of VC involves an uprising of oxidative stress, for which antioxidants can be theoretically effective. However, astaxanthin, a potent antioxidant, has not been tested before for the purpose of managing VC. Read More

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November 2020

Application of conventional ultrasound coupled with virtual touch tissue imaging and quantification in the assessment of muscle strength.

Ann Palliat Med 2020 Sep;9(5):3402-3409

Department of Ultrasound, Chengdu First People's Hospital, Chengdu, China.

Background: Grip strength is the gold standard for the assessment of muscle strength. The current methods of measuring grip strength can only reflect the overall function of the muscle group, not an actual muscle lesion or the cause of the lesion. Virtual touch tissue imaging and quantification (VTIQ) technology can provide a representation of muscle properties and quantify alterations in muscle mechanics through measurements of the mean shear wave velocities of the muscle group at a designated location. Read More

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September 2020

Beneficial nonmotor effects of subthalamic and pallidal neurostimulation in Parkinson's disease.

Brain Stimul 2020 Nov - Dec;13(6):1697-1705. Epub 2020 Oct 7.

University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Neurology, Cologne, Germany; Department of Neurology, University Hospital Giessen and Marburg, Campus Marburg, Germany.

Background: Subthalamic (STN) and pallidal (GPi) deep brain stimulation (DBS) improve quality of life, motor, and nonmotor symptoms (NMS) in advanced Parkinson's disease (PD). However, few studies have compared their nonmotor effects.

Objective: To compare nonmotor effects of STN-DBS and GPi-DBS. Read More

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Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study.

J Food Biochem 2020 12 6;44(12):e13507. Epub 2020 Oct 6.

Akay Natural Ingredients Pvt. Ltd., Cochin, India.

The present randomized, double-blinded, placebo-controlled study investigated the effect of a standardized fenugreek extract (FHE) on perimenopausal discomforts and its influence on hormonal balance and safety. Healthy women characterized with perimenopausal symptoms (n = 48), as assessed by MRS questionnaire, were randomized either to FHE (n = 24) or placebo (n = 24) and supplemented with 250 mg × 2/day for 42 days. Both inter and intra-group comparison revealed a significant improvement in somatic, psychological, and urogenital scores in FHE group, especially for hot flashes (25. Read More

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December 2020

Molecular characterization and systematic analysis of NtAP2/ERF in tobacco and functional determination of NtRAV-4 under drought stress.

Plant Physiol Biochem 2020 Nov 25;156:420-435. Epub 2020 Sep 25.

National Tobacco Cultivation & Physiology & Biochemistry Research Centre, College of Tobacco Science, Henan Agricultural University, Zhengzhou, 450002, China. Electronic address:

The APETALA2/ethylene response factor (AP2/ERF) transcription factor (TF) superfamily play crucial roles in plant growth and development as well as biotic and abiotic stresses response. Here, we systematically characterized 375 AP2/ERF TFs in the Nicotiana tabacum genome. Phylogenetic tree topology and conserved domain number allowed TF classifications into three families of 29 AP2, 341 ERF, and 5 RAV genes, which were unevenly distributed throughout 24 tobacco chromosomes. Read More

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November 2020

Comparison of smartphone-camera and conventional flatbed scanner images for analytical evaluation of chewing function.

J Oral Rehabil 2020 Dec 8;47(12):1496-1502. Epub 2020 Oct 8.

Clinic of General, Special Care, and Geriatric Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.

Background: The two-colour mixing test is a quick method to assess chewing function (CF). The use of smartphone cameras for acquiring images may help in further simplifying the process.

Objective: This study evaluated the reliability of smartphone-camera images of chewing gums to assess CF. Read More

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December 2020

Evaluation of titanium-prepared platelet-rich fibrin and leucocyte platelet-rich fibrin in the treatment of intra-bony defects: A randomized clinical trial.

J Dent Res Dent Clin Dent Prospects 2020 17;14(2):83-91. Epub 2020 Jun 17.

Department of Periodontology and Implantology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India.

Various treatment modalities, such as leucocyte platelet-rich fibrin (L-PRF), bone grafts, and membranes, have been used for the restoration of lost periodontal tissues. Titanium-prepared platelet-rich fibrin (T-PRF) has attracted attention for its proper haemocompatibility, thick fibrin meshwork, and long resorption time. The present study aimed to evaluate the effectiveness of T-PRF and L-PRF in the management of intra-bony defects based on clinical and radiographic criteria. Read More

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Prediction of Salmonella serovars isolated from clinical and food matrices in Lebanon and genomic-based investigation focusing on Enteritidis serovar.

Int J Food Microbiol 2020 Nov 16;333:108831. Epub 2020 Aug 16.

Paris-Est University, French Agency for Food, Environmental and Occupational Health and Safety (Anses), Laboratory for Food Safety (LSAL), Maisons-Alfort, France. Electronic address:

Salmonella enterica subsp. enterica serovars are considered major causes of food poisoning and we performed this study because Salmonella is a burden in Lebanon. The present study investigated the ability of genomic information to predict serovar using a collection of Salmonella isolates from infected humans (n = 24) and contaminated food (n = 63) in Lebanon. Read More

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November 2020

An investigation of the effects of an anger management psychoeducation programme on psychological resilience and affect of intensive care nurses.

Nazan Turan

Intensive Crit Care Nurs 2021 Feb 20;62:102915. Epub 2020 Aug 20.

Nursing Department, Ufuk University, Ankara, Turkey. Electronic address:

Background: It is known that intensive care nurses experience stressful events more frequently than nurses working in other units. Experiencing stressful events frequently may reduce the psychological resilience of intensive care nurses and cause them to express their tension and negative emotions as anger. However, nurses' failure to manage their anger may also lead to medical errors and adversely affect the quality of healthcare services. Read More

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February 2021

A comparison of application frequency of physical therapy modalities in patients with chronic mechanical low back pain.

Turk J Phys Med Rehabil 2020 Jun 18;66(2):201-209. Epub 2020 May 18.

Department of Physical Medicine and Rehabilitation, Istanbul Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey.

Objectives: This study aims to evaluate the effects of physical therapy modalities five days a week versus twice a week with a three-day interval on pain, depression, and functional disability in patients with chronic mechanical low back pain.

Patients And Methods: Between June 2018 and November 2018, a total of 60 patients (39 females, 21 males; mean age 41.0±6. Read More

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F-NaF PET uptake characteristics of coronary artery culprit lesions in a cohort of patients of acute coronary syndrome with ST-elevation myocardial infarction and chronic stable angina: A hybrid fluoride PET/CTCA study.

J Nucl Cardiol 2020 Jul 27. Epub 2020 Jul 27.

Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: F-NaF PET/CT identifies high-risk plaques due to active calcification in coronary arteries with potential to characterize plaques in ST-elevation myocardial infarction (MI) and chronic stable angina (CSA) patients.

Methods: Twenty-four MI and 17 CSA patients were evaluated with F-NaF PET/CTCA for SUV and TBR values of culprit and non-culprit plaques in both groups (inter-group and intra-group comparison), and pre- and post-interventional MI plaques sub-analysis.

Results: Culprit plaques in MI patients had significantly higher SUV (1. Read More

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Label-Free Infrared Spectral Histology of Skin Tissue Part I: Impact of Lumican on Extracellular Matrix Integrity.

Front Cell Dev Biol 2020 12;8:320. Epub 2020 May 12.

Université de Reims Champagne-Ardenne, Laboratoire de Biochimie Médicale et Biologie Moléculaire, Reims, France.

Proteoglycans (PG) play an important role in maintaining the extracellular matrix (ECM) integrity. Lumican, a small leucine rich PG, is one such actor capable of regulating such properties. In this study, the integrity of the dermis of lumican-deleted vs. Read More

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Influence of different photosensitizers on push-out bond strength of fiber post to radicular dentin.

Photodiagnosis Photodyn Ther 2020 Sep 11;31:101805. Epub 2020 May 11.

Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia; Research Chair for Biological Research in Dental Health , King Saud University, Riyadh, Saudi Arabia. Electronic address:

Background: To evaluate the effect of different photosensitizer on extrusion bond strength of glass fiber post to radicular dentin.

Material And Methods: Forty maxillary and mandibular central incisors were disinfected and decoronated. Mechanical instrumentation of canal was performed using protaper NiTi. Read More

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September 2020

Erosive Potential of 1% Phytic Acid on Radicular Dentine at Different Time Intervals.

Eur Endod J 2020 17;5(1):28-34. Epub 2020 Mar 17.

Department of Operative Dentistry, Dr. Ishrat ul Ibad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan.

Objective: The objective of this in-vitro study was to compare the erosive potential and smear layer removal ability of 1% Phytic acid (IP6) and 17% Ethylenediaminetetaacetic acid (EDTA).

Methods: Canal preparation of 225 single rooted extracted human teeth was performed with Protaper NiTi rotary instruments. Teeth were divided into three groups according to the final irrigation protocol. Read More

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Prefrontal functional connectivity analysis of cognitive decline for early diagnosis of mild cognitive impairment: a functional near-infrared spectroscopy study.

Biomed Opt Express 2020 Apr 2;11(4):1725-1741. Epub 2020 Mar 2.

Department of Information and Communication Engineering, DGIST, Daegu 42988, South Korea.

Cognitive decline (CD) is a major symptom of mild cognitive impairment (MCI). Patients with MCI have an increased likelihood of developing Alzheimer's disease (AD). Although a cure for AD is currently lacking, medication therapies and/or daily training in the early stage can alleviate disease progression and improve patients' quality of life. Read More

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Effect of pre-cesarean foot reflexology massage on anxiety of primiparous women.

J Complement Integr Med 2020 Sep 23;17(3). Epub 2020 Sep 23.

Pregnancy Health Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Introduction Anxiety is a common feeling in cesarean section and lack of attention to it is associated with negative consequences for health of mother and child. Reflexology is a way to reduce anxiety. So far, the effect of reflexology on pre-cesarean anxiety has not been evaluated. Read More

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September 2020