190,561 results match your criteria retrospective review

Management of intractable oronasal bleeding using Sengstaken-Blakemore tubes in patients with facial trauma: a case series and technical notes.

Clin Exp Emerg Med 2021 Mar 31;8(1):65-70. Epub 2021 Mar 31.

Department of Emergency Medicine, Ajou University School of Medicine, Suwon, Korea.

Objective: Intractable massive oronasal bleeding can become a life-threatening condition. The success rate of conventional bleeding control methods other than transarterial embolization (TAE) is not expected to be high. We investigated the efficacy of Sengstaken-Blakemore tube (SBT) balloon tamponade in patients with sustained and intractable oronasal bleeding secondary to facial injury. Read More

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Efficacy of Internal Neurolysis for Trigeminal Neuralgia without Vascular Compression.

J Neurol Surg A Cent Eur Neurosurg 2021 Apr 12. Epub 2021 Apr 12.

Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medial University, Hefei, Republic of China.

Background And Objective:  Trigeminal neuralgia is a common neurologic disease that seriously impacts a patient's quality of life. We retrospectively investigated the efficacy and safety of internal neurolysis (nerve combing) for trigeminal neuralgia without vascular compression.

Patients And Methods:  This study was a retrospective review of all patients with trigeminal neuralgia who were admitted between January 2014 and February 2019. Read More

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Predictive factors for success of awake proning in hypoxemic respiratory failure secondary to COVID-19: A retrospective cohort study.

Respir Med 2021 Apr 2;181:106379. Epub 2021 Apr 2.

Department of Internal Medicine, Divisions of Critical Care, Pulmonary and Sleep Medicine, University of Texas Health Science Center at Houston, McGovern Medical School, TX, 77030, USA. Electronic address:

Background: Awake prone positioning has been recommended as an adjunctive measure in spontaneously breathing patients with hypoxemic respiratory failure during the COVID-19 pandemic. It remains uncertain as to how long this should be implemented, what variables to follow and who would be the ideal candidates for this adjunctive therapy.

Methods: A retrospective chart review of patients admitted from April to August 2020 within our institution with multifocal pneumonia and hypoxemic respiratory failure secondary to COVID-19 who underwent awake-proning for at least 3 hours was conducted. Read More

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Prophylactic Use of Negative Pressure Therapy in General Abdominal Surgery: A Systematic Review and Meta-Analysis.

Surg Infect (Larchmt) 2021 Apr 12. Epub 2021 Apr 12.

Department of General, Visceral, and Transplantation Surgery, Clinic and University Hospital Virgen de la Arrixaca, IMIB-ARRIXACA, Murcia, Spain.

Surgical site infections (SSIs) represent an economic burden to healthcare systems. The use of negative pressure wound therapy (NPWT) for SSI prophylaxis remains uncertain. A systematic literature search was conducted in Medline/PubMed, CINAHL, and Web of Science for relevant studies. Read More

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Nutritional Status at Diagnosis, During, and After Treatment in Adolescents and Young Adults with Cancer.

J Adolesc Young Adult Oncol 2021 Apr 12. Epub 2021 Apr 12.

Youth Cancer Service, Royal Adelaide Hospital, Adelaide, South Australia.

Malnutrition is commonly observed during cancer treatment, while some cancer survivors are at risk of overweight and obesity. This study investigated nutritional status during and after treatment in adolescents and young adults (AYA) with cancer. A retrospective chart review of AYA diagnosed with cancer was conducted. Read More

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Preserving NLST mortality benefits and acceptable morbidity for lung cancer surgery in a community hospital.

J Surg Oncol 2021 Apr 12. Epub 2021 Apr 12.

Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Background And Objectives: The aim of this study was to demonstrate whether academic thoracic surgeons could achieve morbidity and mortality rates in community hospitals equivalent to those seen in National Lung Screening Trial (NLST).

Methods: This was a retrospective review of community hospital lung cancer procedures for clinical Stage I-III non-small-cell lung cancers from 2007 through 2014. Variables include age, comorbidities, computed tomography (CT) characterization, and operative techniques. Read More

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[Multicenter retrospective study about the epidemiological, clinical and therapeutic aspects of Kawasaki disease in children from Panama].

Rev Chilena Infectol 2020 Dec;37(6):675-682

Centro de Ciencias Médicas, Hospital Nacional de Niños, Caja Costarricense de Seguro Social, San José, Costa Rica.

Background: Kawasaki disease (KD) is the leading cause of pediatric acquired heart disease in many countries, however, there are few published studies from Latin America (LA).

Aim: To describe the epidemiology, clinical aspects, and treatment of KD in children from Panama as part of the REKAMLATINA-2 in LA.

Methods: Retrospective descriptive review of hospitalized patients diagnosed with KD, attended at three main pediatric hospitals of Panama from January-1-2009 to December-31-2013. Read More

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December 2020

Clinical concern for necrotising fasciitis: a review of referrals to plastic surgery units at two tertiary centres.

ANZ J Surg 2021 Apr 12. Epub 2021 Apr 12.

Plastic Surgery, Peninsula Health, Melbourne, Victoria, Australia.

Objectives: To evaluate the impact of clinical suspicion on the diagnosis of necrotising fasciitis (NF) in two inpatient plastic surgery units.

Methods: A multicentre retrospective audit of all referrals of adult patients to the inpatient plastic surgery units of two Melbourne metropolitan tertiary centres from 1 February 2018 to 31 December 2018.

Results: A total of 53 patients (37 male, 16 female) were referred to evaluate for NF. Read More

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Trans-oral robotic surgery: a safe and effective tool in head and neck surgery in an Australian rural setting.

ANZ J Surg 2021 Apr 12. Epub 2021 Apr 12.

Ear, Nose and Throat Department, Toowoomba Hospital, Toowoomba, Queensland, Australia.

Background: Trans-oral robotic surgery (TORS) facilitates surgical resection of tumours as an alternative to open surgery and has demonstrated favourable oncological results. Given the novelty of TORS and the paucity of evidence on TORS-specific complications in a rural setting, we report our experience with TORS at an Australian rural head and neck centre.

Methods: A retrospective review of all robotic cases performed at a regional head and neck centre in Queensland was undertaken from 2014 to 2019. Read More

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Laparoscopic versus robotic-assisted Heller myotomy for the treatment of achalasia: A systematic review with meta-analysis.

Int J Med Robot 2021 Mar 24:e2253. Epub 2021 Mar 24.

Division of General, Minimally Invasive & Robotic Surgery, University of Illinois Hospital & Health Sciences System, Chicago, Illinois, USA.

Background: Robotic-assisted laparoscopic Heller myotomy has been proposed as an alternative minimally invasive approach to traditional laparoscopy for the treatment of achalasia. This systematic review aims to compare the safety and post-operative outcomes of the two procedures.

Methods: Systematic literature search was performed in MEDLINE through Ovid, Scopus and Cochrane to identify clinical trials and retrospective analyses. Read More

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Navigation assisted total knee arthroplasty in 54,114 patients: No increased risk in acute complications and hospital utilisation.

Int J Med Robot 2021 Apr 2:e2256. Epub 2021 Apr 2.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA.

Background: The advent of navigation in total knee arthroplasty (TKA) has generated interest in attempt to improve component positioning as desired and clinical outcomes. The aim of this study was to evaluate 90-day complication and cost of navigation-assisted TKAs (NTKA) compared to conventional TKAs (CTKA) using a national database.

Methods: A retrospective review of national database was conducted on all patients who underwent TKA from 2010 and 2017. Read More

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Evolution of surgical management for phaeochromocytoma over a 17-year period: an Australian perspective.

ANZ J Surg 2021 Apr 12. Epub 2021 Apr 12.

Department of General Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Background: Minimally invasive adrenalectomy and advances in anaesthetic techniques have transformed surgery for phaeochromocytoma. This 17-year review describes the evolution of phaeochromocytoma care in our unit.

Methods: We performed a retrospective cohort review of all patients who underwent adrenalectomy for phaeochromocytoma from 2000 to 2016. Read More

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Early planned labor induction vs expectant management in late preterm pre-labor rupture of membranes: maternal and neonatal outcomes.

Ginekol Pol 2021 Apr 12. Epub 2021 Apr 12.

The Azrieli faculty of Medicine, Bar-Ilan University, Safed, Israel.

Objectives: To compare expectant management with early planned labor induction in pregnancies complicated by late preterm pre-labor rupture of membranes (PPROM).

Material And Methods: A retrospective file review was conducted in a single tertiary center from January 2015 to Sep-tember 2019. Singleton pregnancies complicated by late PPROM at 34-36 completed weeks of gestation were enrolled. Read More

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Cytogenetic analysis of early pregnancy loss after assisted reproduction treatment using intracytoplasmic sperm injection.

Ginekol Pol 2021 Apr 12. Epub 2021 Apr 12.

Beykent University, Department of Nutrition and Dietetics, Istanbul, Turkey.

Objectives: To evaluate the incidence of numerical chromosomal abnormalities in the patients with early pregnancy loss (EPL) following in vitro fertilization, and evaluate the role of different confounders of the risk of chromosomal abnormality- related pregnancy loss.

Material And Methods: A retrospective chart review of all patients from our in vitro fertilization (IVF) center who conceived using assisted reproduction techniques between April 2017 and 2019, who experienced a subsequent early pregnancy loss, and whose abortus materials were successfully karyotyped were included.

Results: Of the 243 patients experienced an early loss, the overall rate of chromosomal abnormality was 46. Read More

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Incidence of Infections and Malignancy Among Elderly Male Patients with IBD Exposed to Vedolizumab, Prednisone, and 5-ASA Medications: A Nationwide Retrospective Cohort Study.

Adv Ther 2021 Apr 12. Epub 2021 Apr 12.

Department of Gastroenterology, Corporal Michael J Crescenz VA Medical Center, 3900 Woodland Avenue, Philadelphia, PA, 19104, USA.

Introduction: Vedolizumab (VDZ) is postulated to have a potentially safer side effect profile than other biologic medications owing to its gut-selective mechanism. However, extrapolating these safety data to older patients is challenging because of their underrepresentation in or exclusion from most clinical trials, higher rates of withdrawal, and higher rates of comorbidities. Our aim was to evaluate the absolute risk of infections and malignancies in an elderly group of patients with inflammatory bowel disease (IBD) exposed to VDZ vs. Read More

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Sinonasal mucosal melanoma: treatment strategies and survival rates for a rare disease entity : A single center experience and review of literature.

Wien Klin Wochenschr 2021 Apr 12. Epub 2021 Apr 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, Auenbruggerplatz 26, 8036, Graz, Austria.

Background: Sinonasal mucosal melanoma (SNMM) is a rare disease entity comprising 0.4-1.3% of all melanomas. Read More

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Pre-diagnosis major life stressors and breast cancer outcomes.

Breast Cancer Res Treat 2021 Apr 12. Epub 2021 Apr 12.

Department of Radiation Oncology, Jacoby Center for Breast Health, Mayo Clinic, Jacksonville, FL, USA.

Purpose: While the association between diagnosis of breast cancer and post-diagnosis psychological distress has been well documented, data regarding pre-diagnosis psychological distress in the breast cancer population are limited. Here, we assessed pre-diagnosis major life stressors and breast cancer outcomes, namely stage of disease and choice of surgery, in a single-center population.

Methods: Patients with newly diagnosed clinical stage 0-3 breast cancer seen at Mayo Clinic Florida between June 11, 2018, and October 7, 2019, were administered voluntary telephone surveys to assess major life stressors during the 24 months preceding their cancer diagnosis. Read More

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Validating Data-driven Methods to Identify Transgender Individuals in the Veterans Affairs.

Am J Epidemiol 2021 Apr 12. Epub 2021 Apr 12.

Center for Healthcare Organization and Implementation Research (CHOIR), VA Bedford Healthcare System, Bedford, Massachusetts, United States.

We sought to operationalize and validate data-driven approaches to identify transgender individuals in the U.S. Department of Veteran Affairs (VA) health care system through a retrospective analysis using VA administrative data from 2006 to 2018. Read More

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Hip Morphology in Early-stage LCPD: Is There an Argument for Anatomic-specific Containment?

J Pediatr Orthop 2021 Apr 12. Epub 2021 Apr 12.

Children's Hospital of Colorado, Aurora, CO Division of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA Children's Orthopedic Center Children's Hospital Los Angeles, Los Angeles, CA Children's Healthcare of Atlanta, Atlanta, GA Gillette Children's Specialty Healthcare, St. Paul Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN Texas Scottish Rite Hospital for Children Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

Background: Early containment surgery has become increasingly popular in Legg-Calvé-Perthes Disease (LCPD), especially for older children. These procedures treat the proximal femur, the acetabulum, or both, and most surgeons endorse the same surgical option regardless of an individual patient's anatomy. This "one-surgery-fits-all" approach fails to consider potential variations in baseline anatomy that may make one option more sensible than another. Read More

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A fully automated inpatient transport system.

Technol Health Care 2021 Apr 2. Epub 2021 Apr 2.

Department of Internal Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.

Background: The transport of the inpatients to and from locations inside the hospital can vary in complexity depending on the patient location, status, and logistical needs. Most transport systems have not developed at the same speed as other medically related technologies. We conducted a pilot study of a new automated transport system for patients within the hospital. Read More

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Cumulative diagnostic imaging radiation exposure in premature neonates.

J Neonatal Perinatal Med 2021 Apr 7. Epub 2021 Apr 7.

Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA.

Background: To date, there has been limited work evaluating the total cumulative effective radiation dose received by infants in the neonatal intensive care unit. Most previous publications report that the total radiation dose received falls within the safe limits but does not include all types of ionizing radiation studies typically performed on this vulnerable patient population. We aimed to provide an estimate of the cumulative effective ionizing radiation dose (cED) in microSieverts (μSv) received by premature infants ≤32 weeks from diagnostic studies performed throughout their NICU stay, and predictors of exposures. Read More

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Impact of opioid maintenance treatment during pregnancy on neonatal birth weight and head circumference.

J Neonatal Perinatal Med 2021 Apr 7. Epub 2021 Apr 7.

Division of Neonatology, Hurley Medical Center, Flint, MI, USA.

Background: Pregnant mothers with opioid dependency commonly receive maintenance treatment of opioid (OMT), either as buprenorphine (BMT) or methadone maintenance treatment (MMT). We investigated, whether OMT adversely affects standardized neonatal anthropometric outcomes and whether BMT is potentially safer than MMT in this regard.

Methods: Retrospective chart review of mother infant dyad, with and without OMT. Read More

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Sustained long-term benefits of patient support program participation in immune-mediated diseases: improved medication-taking behavior and lower risk of a hospital visit.

J Manag Care Spec Pharm 2021 Apr 12:1-11. Epub 2021 Apr 12.

AbbVie Inc., North Chicago, IL.

Patient support programs (PSPs) improve medication-taking behavior in the first 12 months of treatment for patients with immune-mediated diseases, but it is unknown if these benefits are sustained. As immune-mediated diseases continue to increase in prevalence and economic burden, understanding the potential value of PSPs in helping patients adhere to their long-term treatment plan and avoid costly hospital visits is crucial. Launched nationally in 2015, HUMIRA Complete (a PSP for adalimumab patients) provides an opportunity to study long-term effects of PSP participation, including the impact on medication-taking behavior and hospital visits. Read More

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High risk of relapse with intermediate dose cytarabine for consolidation in young favourable-risk acute myeloid leukaemia patients following induction with 7+3: a retrospective multicentre analysis and critical review of the literature.

Br J Haematol 2021 Apr 11. Epub 2021 Apr 11.

Division of Hematology, Oncology, Blood and Marrow Transplantation, University of Minnesota, Minneapolis, USA.

Following the 2017 European LeukemiaNet (ELN) guidelines, we changed our practice from using high-dose cytarabine (HIDAC-3 g/m q12h-D1,3,5) to intermediate-dose cytarabine (IDAC-1·5 g/m q12h-D1,3,5/D1-3) for consolidation in young(<60 years) favourable-risk acute myeloid leukaemia (AML) patients. We assessed the clinical impact of this practice change. Of 80 patients, 51 received HIDAC prior to the protocol change, and subsequently, 29 received IDAC. Read More

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Safety of video-based telemedicine compared to in-person triage in emergency ophthalmology during COVID-19.

EClinicalMedicine 2021 Apr 5:100818. Epub 2021 Apr 5.

Department of Digital Medicine, Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, United Kingdom.

Background: the need for social distancing midst the COVID-19 pandemic has forced ophthalmologists to innovate with telemedicine. The novel process of triaging emergency ophthalmology patients via videoconsultations should reduce hospital attendances. However, the safety profile of such services were unknown. Read More

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Bevacizumab Treatment of Radiation-Induced Brain Necrosis: A Systematic Review.

Front Oncol 2021 25;11:593449. Epub 2021 Mar 25.

Department of Radiation Oncology, Shenzhen People's Hospital, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.

Background: Radiation brain necrosis (RBN) is a serious complication in patients receiving radiotherapy for intracranial disease. Many studies have investigated the efficacy and safety of bevacizumab in patients with RBN. In the present study, we systematically reviewed the medical literature for studies reporting the efficacy and safety of bevacizumab, as well as for studies comparing bevacizumab with corticosteroids. Read More

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Lateral approach improves surgical access to the superior pole in giant endemic goiters.

Gland Surg 2021 Mar;10(3):973-979

Department of Otolaryngology Head and Neck Surgery, Tufts University Medical Center, Boston, Massachusetts, USA.

Background: Surgical management of mega-goiters in endemic areas with extreme iodine deficiency presents unique challenges. Based on our initial 5-year experience (2007 to 2011) operating on mega-goiters in Gitwe, Rwanda, Africa, we modified our technique to a lateral approach which affords better exposure of the superior pole vessels and other vital neurovascular structures, thereby improving safety. We describe this lateral approach technique and review outcomes compared to the standard technique. Read More

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Usefulness of the Wisconsin and CaPTHUS indices for predicting multiglandular disease in patients with primary hyperparathyroidism in a southern European population.

Gland Surg 2021 Mar;10(3):861-869

Department of Surgery, Virgen de las Nieves University Hospital, Granada, Spain.

Background: Focused parathyroidectomy is a safe technique for the treatment of primary hyperparathyroidism. The CaPTHUS score and the Wisconsin index are preoperative diagnostic tools designed to distinguish between single- and multigland disease. The aim of the study is to evaluate the usefulness of these models for predicting multiglandular disease in a European population. Read More

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Narrative Review of Clinical Productivity and Teaching in Emergency Medicine.

Cureus 2021 Apr 5;13(4):e14309. Epub 2021 Apr 5.

Department of Emergency Medicine, The Ohio State University, Columbus, USA.

Emergency medicine educators are subject to external pressures to increase clinical productivity while maintaining quality teaching. Strategies to mitigate this perceived conflict include alterations in staffing and incentive compensation with educational value units. There is a paucity of information describing the effect of clinical demands on teaching metrics in emergency medicine. Read More

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Improving Incident Reporting in a Hospital-Based Radiation Oncology Department: The Impact of a Customized Crew Resource Training and Event Reporting Intervention.

Cureus 2021 Apr 5;13(4):e14298. Epub 2021 Apr 5.

Curriculum and Accreditation, Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, USA.

Background Radiation oncology (RO) is a high-risk environment with an increased potential for error due to the complex automated and manual interactions between heterogeneous teams and advanced technologies. Errors involving procedural deviations-- can adversely impact patient morbidity and mortality. Under-reporting of errors is common in healthcare for reasons such as fear of retribution, liability, embarrassment, etc. Read More

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